Could You Be On Mk-677 Year Round?

[EvropaCel]

Since it's not a SARM or a steroid and it's not suppressive could you theoretically take Mk-677 365 days a year? Or would you still need to cycle for whatever reason?

 

[Gosick]

lt bloats your face, makes you hungry, and makes you tired all the tlme

lts good for rottlng, so go for lt

 

[Deleted member 2756]

Insulin and GH are somewhat reciprocal due to the fact that your liver will produce IGF-1 when both are in your body in ample amounts. MK677 being a GHRH which is a Ghrelin receptor agonist as well as a GH secretagogue, will mean you'd be forcing your pancreas to secrete Insulin even when GH is being secreted by the pituitary. That's dangerous because it's abnormal.

Heightened Ghrelin = Hunger. Eating makes your pancreas secrete Insulin which is supposed to lower blood sugar by transporting glucose out of the blood. But the GH itself is already working at keeping your blood glucose low.

So when Insulin is sent to do it's job to lower the glucose levels in your blood, but it finds that your levels are already low; it still transports more glucose to cells that need it, from your blood; creating a hypoglycemic scenario.

If the Ghrelin wasn't around to trick your body into thinking you need energy and calories (because you're hungry), the Insulin wouldn't lower your already low blood glucose levels.

The pancreas is also tricked into producing too much Insulin, which can't do it's job properly due to other complications; and that's essentially what Insulin Resistance is.

When you're highly Insulin sensitive; your pancreas only creates insulin when you are in an energy abundance; which makes sense since calories and amino acids cause insulin secretion. On the other hand, when your body is in an energy deficit, your pancreas doesn't need to secrete Insulin, because there's no purpose to do that. Your pancreas gets a break whilst your cells and tissues sensitize and get a break from inbound glucose being transported from the blood.

When the cells have too much glucose, and the blood has too little; and your body is recruiting Insulin rather than Glucagon; you're fucking yourself up.

- @Seth Walsh

thought he summed it up pretty well, TLDR: don't take it at all, will directly cause insulin resistance.

 

[OCDMaxxing]

bloats you, avoid, looksmin

 

[EvropaCel]

Insulin and GH are somewhat reciprocal due to the fact that your liver will produce IGF-1 when both are in your body in ample amounts. MK677 being a GHRH which is a Ghrelin receptor agonist as well as a GH secretagogue, will mean you'd be forcing your pancreas to secrete Insulin even when GH is being secreted by the pituitary. That's dangerous because it's abnormal.

Heightened Ghrelin = Hunger. Eating makes your pancreas secrete Insulin which is supposed to lower blood sugar by transporting glucose out of the blood. But the GH itself is already working at keeping your blood glucose low.

So when Insulin is sent to do it's job to lower the glucose levels in your blood, but it finds that your levels are already low; it still transports more glucose to cells that need it, from your blood; creating a hypoglycemic scenario.

If the Ghrelin wasn't around to trick your body into thinking you need energy and calories (because you're hungry), the Insulin wouldn't lower your already low blood glucose levels.

The pancreas is also tricked into producing too much Insulin, which can't do it's job properly due to other complications; and that's essentially what Insulin Resistance is.

When you're highly Insulin sensitive; your pancreas only creates insulin when you are in an energy abundance; which makes sense since calories and amino acids cause insulin secretion. On the other hand, when your body is in an energy deficit, your pancreas doesn't need to secrete Insulin, because there's no purpose to do that. Your pancreas gets a break whilst your cells and tissues sensitize and get a break from inbound glucose being transported from the blood.

When the cells have too much glucose, and the blood has too little; and your body is recruiting Insulin rather than Glucagon; you're fucking yourself up.

- @Seth Walsh

thought he summed it up pretty well, TLDR: don't take it at all, will directly cause insulin resistance.

da faq, well I have like 40 ml left so I'm gonna atleast finish that shit and hope I don't die or whatever. Been eating a fuck ton tho which is good cause I'm tryna gain. What thread is that from?