Do Androgen Receptors upregulate and build a tolerance to AAS?

[Deleted member 2268]

If someone were to run 500 test once and then run it a second time would they see less gains? Or would the same dose have the same impact every time?

 

[VladimirtheGreat]

If someone were to run 500 test once and then run it a second time would they see less gains? Or would the same dose have the same impact every time?

Watch for your strenght and weight...if it doesnt rise,than up the dose from previous time..i did first and second 500, than third 750

 

[BrownBoy]

becomes harder as you go past your genetic potential, but not because of the downregulation of receptors

 

[Deleted member 2268]

becomes harder as you go past your genetic potential, but not because of the downregulation of receptors

So you think for a second cycle it’s worth adding orals or other shit?

 

[Deleted member 2268]

Watch for your strenght and weight...if it doesnt rise,than up the dose from previous time..i did first and second 500, than third 750

This is based on calories too. They say first up your calories and if you don’t see results then up the dose.

 

[Deleted member 2268]

Watch for your strenght and weight...if it doesnt rise,than up the dose from previous time..i did first and second 500, than third 750

How was 750 compared to 500?

 

[VladimirtheGreat]

This is based on calories too. They say first up your calories and if you don’t see results then up the dose.

Yes,

 

[VladimirtheGreat]

How was 750 compared to 500?

I didnt do test solo,i did 750 test,400 tren a,and 400 masteron...it was bomb...the pumps and veins were all over...but its not that difference between 500 and 750 test

 

[Deleted member 2268]

I didnt do test solo,i did 750 test,400 tren a,and 400 masteron...it was bomb...the pumps and veins were all over...but its not that difference between 500 and 750 test

No hair loss or other sides from tren and mast?

 

[Deleted member 20652]

If someone were to run 500 test once and then run it a second time would they see less gains? Or would the same dose have the same impact every time?

NO

Complete opposite effect. Androgen receptors don't work the same as neurotransmitter receptors

Injecting Testosterone actually increase your androgen receptors

The higher dosage Testosterone you inject and the more FREQUENT your Testosterone injections are the more androgen receptors your body will start building

High dosage Testosterone + Frequent injections (like a week dose divided by 2 or 3 times a week instead of once a week , or every other day injections) will increase your androgen receptors even more

I recommend listening to the Steroid Podcast on spotify by Dan the bodybuilder in thailand. He talks a lot about this topic.

//Thomas DOM

 

[Deleted member 2268]

NO

Complete opposite effect. Androgen receptors don't work the same as neurotransmitter receptors

The higher dosage Testosterone you inject and the more FREQUENT your Testosterone injections are the more androgen receptors your body will start building

High dosage Testosterone + Frequent injections (like a week dose divided by 2 or 3 times a week instead of once a week , or every other day injections) will increase your androgen receptors even more

I recommend listening to the Steroid Podcast on spotify by Dan the bodybuilder in thailand. He talks a lot about this topic.

//Thomas DOM

So how does this impact gains? Your saying injecting more frequently is better? I thought it only helps with maintaining stable levels and less fluctuations in estro.

 

[Deleted member 20652]

So how does this impact gains? Your saying injecting more frequently is better? I thought it only helps with maintaining stable levels and less fluctuations in estro.

Frequent injections gives you best gains cause more androgen receptors

Everytime you inject your body builds up more androgen receptors

How's your current regime?

I do 125 mg every 3.5 days (a total 250 per week divided by 2)

Every other day frequency is even better If you wanna do that

 

[Deleted member 2268]

Frequent injections gives you best gains cause more androgen receptors

Everytime you inject your body builds up more androgen receptors

How's your current regime?

I do 125 mg every 3.5 days (a total 250 per week divided by 2)

Every other day frequency is even better If you wanna do that

I do 62.5 mg cyp every 3.5 days. I have been cruising for a long time now on this dose. You’re cruising on 250 mg?

 

[Deleted member 20652]

I do 62.5 mg cyp every 3.5 days. I have been cruising for a long time now on this dose. You’re cruising on 250 mg?

Yeah I'm cruising now cause too busy with work to get into bodybuilding

If I have time for lifting I might increase the dose a bit

 

[Deleted member 2268]

Yeah I'm cruising now cause too busy with work to get into bodybuilding

Why are you cruising on 250 mg? I feel that’s borderline blast cycle. Don’t you want to let your lipids recover so you can blast? I’m sure you can maintain your physique on 125 mg without impacting your health.

 

[Deleted member 20652]

How long you been using testosterone

Do you use pharmaceutical or underground lab product?

 

[Deleted member 20652]

Why are you cruising on 250 mg? I feel that’s borderline blast cycle. Don’t you want to let your lipids recover so you can blast? I’m sure you can maintain your physique on 125 mg without impacting your health.

250 mg is not bad for lipids

 

[Deleted member 2268]

250 mg is not bad for lipids

Is it better than 125 mg in terms of gains? I am considering just running 250 mg for long periods of tkme instead of blasting and cruising. I don’t think bloodwork is the only issue here, what about cardiac hypertrophy? In general they say cruise on the lowest dose you can get away with and only blast for short periods of time.

 

[Deleted member 20652]

Is it better than 125 mg in terms of gains? I am considering just running 250 mg for long periods of tkme instead of blasting and cruising. I don’t think bloodwork is the only issue here, what about cardiac hypertrophy? In general they say cruise on the lowest dose you can get away with and only blast for short periods of time.

250 mg is better

No don't worry about side effects like that , those side effects is for high dosage Testosterone (500 mg - 1 gram) only

 

[Deleted member 2268]

250 mg is better

No don't worry about side effects like that , those side effects is for high dosage Testosterone (500 mg - 1 gram) only

If I up my cruise dose to 250 mg and keep it at that level year round is there even a point in blasting? I’m sure I could make above natty gains with good diet and avoid the sides of higher blast cycles? Would also be helpful for recomping during cutting. How is your bloodwork on 250 mg?

 

[Deleted member 20652]

Do you fornicate with women?

 

[Deleted member 20652]

If I up my cruise dose to 250 mg and keep it at that level year round is there even a point in blasting? I’m sure I could make above natty gains with good diet and avoid the sides of higher blast cycles? Would also be helpful for recomping during cutting. How is your bloodwork on 250 mg?

I dont do bloodwork

 

[Deleted member 2268]

I dont do bloodwork

Lmao what

 

[Deleted member 20652]

Up the dosage to 250 mg

125 mg is not even too far from natty levels

Peak natty T production is 70 mg a week. Average natty T production is 49 mg a week

125 mg is not that far from it

You gotta up to 250 if you want superior testosterone levels

 

[Deleted member 20652]

Lmao what

No blood work

 

[Deleted member 2268]

Do you fornicate with women?

Yes

 

[Deleted member 20652]

Yes

How? Online dating or what?

 

[Deleted member 2268]

Up the dosage to 250 mg

125 mg is not even too far from natty levels

Peak natty T production is 70 mg a week. Average natty T production is 49 mg a week

125 mg is not that far from it

You gotta up to 250 if you want superior testosterone levels

How much above the normal range would 250 mg put me? On one hand you are saying it’s safe to run this dose but you don’t even bloodwork? Are you not concerned about the impact on lipids wtf

 

[Deleted member 2268]

How? Online dating or what?

Yes I’m over 100 lay count. I used to go out to bars but now just online dating

 

[ItsOverCel]

no
it's just harder to build muscle if you already have high muscle mass and strength

 

[BrownBoy]

How much above the normal range would 250 mg put me? On one hand you are saying it’s safe to run this dose but you don’t even bloodwork? Are you not concerned about the impact on lipids wtf

It's 800-1000 ng/dl MAX lmao. 500>>250

 

[BrownBoy]

Lmao what

I wouldn't take advice from a redneck who doesn't even do bloodwork once in a while

 

[BrownBoy]

So you think for a second cycle it’s worth adding orals or other shit?

if you wanna speed it up, yeah

 

[VladimirtheGreat]

No hair loss or other sides from tren and mast?

No,but i used monoksidil

 

[kalefartbomb]

Yes you won't see cumulative gains if you keep running the same cycle, that's not how it works. Your body composition and nutrient partitioning (assuming equal training and diet) is more or less a direct reflection of your hormone profile whether natty or enhanced. In order to progress you have to continually push your hormone profile which means both adding more compounds and increasing dosages (bodybuilding wisdom is that adding compounds yields better gains than merely increasing dosages since there are fewer diminishing returns on receptors).

 

[Deleted member 17429]

Frequent injections gives you best gains cause more androgen receptors

Everytime you inject your body builds up more androgen receptors

How's your current regime?

I do 125 mg every 3.5 days (a total 250 per week divided by 2)

Every other day frequency is even better If you wanna do that

Wait what? Will I keep the androgen receptors if I inject, and come off?

 

[Deleted member 2268]

Yes you won't see cumulative gains if you keep running the same cycle, that's not how it works. Your body composition (assuming equal training and diet) is more or less a direct reflection of your hormone profile whether natty or enhanced. In order to progress you have to continually push your hormone profile which means both adding more compounds and increasing dosages (bodybuilding wisdom is that adding compounds yields better gains than merely increasing dosages since there are fewer diminishing returns on receptors).

That makes zero sense. There are guys with high natural test that look DYEL. JFL at this