Yes you only read the abstract and nothing else that’s the problem you dumb faggot you have no attention span and you find studies with ai on top of that
nigga i had those in my backpocket i save those studies as pdfs because im a neurodivergent nigga whos arguing at 2am about growth plates in an estonian gay fashion forum do you really think i dont actually read the methodology too? "muh read brooo" wont change consistent findings across groups and the actual machanics of serms acting as agonists to bone.
"Dudeee I'm so ND jfl jfl clavicular I've been on the forums before i had ass hair dnr jfl ahah boyo"
Would 17 be all right to take test?1. Intracrine Aromatization (Local Estrogen)
When you take testosterone durig puberty your blood levels of testosterone will be highly supraphysiological Even if you take a high dose of an AI (like Arimidex or Letrozole , aromasin) to keep your e2 LOW youre aromtise enzym still exist directly inside your bone tissue and growth plates and theres no fucking ai or any other shit to counter that its going to fuse ur shit
when Test goes through tissues and converts to estrogen locally and theres nothing u can do to stop that and
Your blood work might show low estrogen (e2) but the local concentration inside your growth plates will still be happning and make ur plates prematruerly close.
theres also a study that shows kids that were used a tiny bit of test during puberty like 16mg a week 45% of them ended up with deformed spines
u gotta be retarded to do that
theres also other stuff like direct androgenic fusion but i dont have any energy to explain that but idk do wtv u want niggas
“also” im just a sadist, masochism of any form is gay
asin is a sui inhibitor
yes best age
i mean the masochism only theres this dommy mommy it isnt like harcore masochism just degrading and maybe pegging
shes a dommy mommy u would want to bedegraded to fucking nigger we are both switchs ah idk i might be gay for heroh yea ture
do u have any proofs
how can i bellive u
oh sweet how good
My dad is 6'6 and i am predicted to be anywhere between 197-203cm fully grown.
i do horrible things to bitches i fuck even when im trying not to do so nigga, dont involve me with your gay kinks
yeah thats what im planning to do. Halo + test
Thanks1. Intracrine Aromatization (Local Estrogen)
When you take testosterone durig puberty your blood levels of testosterone will be highly supraphysiological Even if you take a high dose of an AI (like Arimidex or Letrozole , aromasin) to keep your e2 LOW youre aromtise enzym still exist directly inside your bone tissue and growth plates and theres no fucking ai or any other shit to counter that its going to fuse ur shit
when Test goes through tissues and converts to estrogen locally and theres nothing u can do to stop that and
Your blood work might show low estrogen (e2) but the local concentration inside your growth plates will still be happning and make ur plates prematruerly close.
theres also a study that shows kids that were used a tiny bit of test during puberty like 16mg a week 45% of them ended up with deformed spines
u gotta be retarded to do that
theres also other stuff like direct androgenic fusion but i dont have any energy to explain that but idk do wtv u want niggas
No shut low iq nigger everyone blasts during puberty
Really good
lol @ it im diagnosed. show me them studies and ill read, niggah.
Nigga tagged all the sub 30 iqs
bro never pulled up the studies @darodiddler ur a retard
he did nigga check it the second section he did show studies
i talking bout you
@peterk1287 1287literally just google it https://pubmed.ncbi.nlm.nih.gov/28679145/
Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival - PMC
Breakdown or absence of vascular oxygen delivery is a hallmark of many common human diseases, including cancer, myocardial infarction, and stroke. The chief mediator of hypoxic response in mammalian tissues is the transcription factor ...pmc.ncbi.nlm.nih.gov
A double-blind, placebo-controlled comparison of letrozole to oxandrolone effects upon growth and puberty of children with constitutional delay of puberty and idiopathic short stature - PubMed
This first randomized controlled clinical trial in CDGD teenage boys with predicted short stature shows that letrozole increases PAH more than oxandrolone and advances pubertal stage and bone mineralization less.pubmed.ncbi.nlm.nih.gov
i knew nigga was gonna send some straight bull shit1. Intracrine Aromatization (Local Estrogen)
When you take testosterone durig puberty your blood levels of testosterone will be highly supraphysiological Even if you take a high dose of an AI (like Arimidex or Letrozole , aromasin) to keep your e2 LOW youre aromtise enzym still exist directly inside your bone tissue and growth plates and theres no fucking ai or any other shit to counter that its going to fuse ur shit
when Test goes through tissues and converts to estrogen locally and theres nothing u can do to stop that and
Your blood work might show low estrogen (e2) but the local concentration inside your growth plates will still be happning and make ur plates prematruerly close.
theres also a study that shows kids that were used a tiny bit of test during puberty like 16mg a week 45% of them ended up with deformed spines
u gotta be retarded to do that
theres also other stuff like direct androgenic fusion but i dont have any energy to explain that but idk do wtv u want niggas
what how is it bs? explain
yo i acc did that the other day recording beating my meat
this right heretheres also a study that shows kids that were used a tiny bit of test during puberty like 16mg a week 45% of them ended up with deformed spines
ohh ur talking abt that study i alreday said it was an outliner read the first section they got deformed because of the ai not the test i forgot to edit the post i couldnt do it after 30 mins ik that
only estrogen fuses the growth plates what do you mean direct androgenic fusion?? + if you are referring to exhaustion of the growth plate scientifically that would not occur in a zero e2 environment. letrozole blocks aromatase in all parts of the body, thats why it has a higher risk on the brain e2 (although the brain development will fully recover within 12 months after use is stopped in males) , this is also why it can practically kill any gyno and has been shown to prevent and severely delay plate fusion even in a high testosterone environment.
yes the bone makes its own estrogen we spoke about that earlier but ais easily cross into bone tissue and destroy the enzyme right at the source the AI absolutely works locally inside the growth plate the only way you fuse while taking an ai is if you blast such an astronomically high dose of Testosterone that you mathematically overpower the drug.@polarpop
polarpop
SO like 100 mgs of test wouldnt fuse me? is it risky tbh idk how would i know its not supressing the drug? am i taking a gamble
60 bro
Fulvestrant is an option, I'm currently looking into it
agreed best test doses is 40-70 or none at all1. Intracrine Aromatization (Local Estrogen)
When you take testosterone durig puberty your blood levels of testosterone will be highly supraphysiological Even if you take a high dose of an AI (like Arimidex or Letrozole , aromasin) to keep your e2 LOW youre aromtise enzym still exist directly inside your bone tissue and growth plates and theres no fucking ai or any other shit to counter that its going to fuse ur shit
when Test goes through tissues and converts to estrogen locally and theres nothing u can do to stop that and
Your blood work might show low estrogen (e2) but the local concentration inside your growth plates will still be happning and make ur plates prematruerly close.
theres also a study that shows kids that were used a tiny bit of test during puberty like 16mg a week 45% of them ended up with deformed spines
u gotta be retarded to do that
theres also other stuff like direct androgenic fusion but i dont have any energy to explain that but idk do wtv u want niggas
DHT-derivatives are not the same as DHT you moron, you don’t have oxandrolone (anavar) and drostanolone (masteron) circulating in your bloodstream
DHT is inactivated by 3a-HSD in muscle tissue very quickly, that’s why DHT-derivatives are preferred as they are modified to resist the 3a-HSD enzyme to actually have an effect in muscle tissue.
“Heavy supera T” if we neglect the absolute dyslexic grammar, as I’ve said, aromatase inhibitors also put your testosterone levels at supraphysiological concentrations.
Don’t debate me please i don’t want to refute ChatGPT for hours straight, if you reply back with AI, i will put you on ignore instantly, so don’t be surprised when i don’t reply back, thinking you cracked the code.
AR activation in chondrocytes doesn’t stunt growth or cause senescence, you don’t know what senescence means, it’s the exhaustion of your growth plate’s proliferative capacity, your plates will already fuse normally through aging before you even reach a state like that through AR activation. This can occur if you’re aromatase deficient and use non-aromatising androgens in like 5-10 years i guess
Androgens don’t deplete the resting zone, estrogen does by aromatising from androstenedione/testosterone you moron.
I already put you on ignore as it’s obvious you wont be able to reply without the use of AI.
im learning alot from you both thank you
i was wrong about the "direct androgenic "fusion hes right
thanks for telling becuz i am way too uninformed to construct my own opinion
so taking a dht derivative is the best way to lower estrogen?1. Intracrine Aromatization (Local Estrogen)
When you take testosterone durig puberty your blood levels of testosterone will be highly supraphysiological Even if you take a high dose of an AI (like Arimidex or Letrozole , aromasin) to keep your e2 LOW youre aromtise enzym still exist directly inside your bone tissue and growth plates and theres no fucking ai or any other shit to counter that its going to fuse ur shit
when Test goes through tissues and converts to estrogen locally and theres nothing u can do to stop that and
Your blood work might show low estrogen (e2) but the local concentration inside your growth plates will still be happning and make ur plates prematruerly close.
theres also a study that shows kids that were used a tiny bit of test during puberty like 16mg a week 45% of them ended up with deformed spines
u gotta be retarded to do that
theres also other stuff like direct androgenic fusion but i dont have any energy to explain that but idk do wtv u want niggas
Read the shit you provide nigger
