Does Enclomiphene agonize ERα in any growth plate cartilage?

[PSLgodBlackPerson]

Researching for hours, closest studies which cover this would be studies on clomiphene (mix of enclomiphene and zuclomiphene). None truly studying growth retardation unless they're popular and known compounds like temox and other serms. Enclomiphene from what I read is largely antagonistic on most tissues, however seems to be positive on bone density, which can possibly infer some agonism to ERα in growth plate cartilage although many factors can contribute to this, and this can be a stretch. Downside to the previous assumption about its possible agonism to ERα within growth plate cartilage is that the studies were using clomiphene where Zuclomiphene can act largely as very bone protective since it generally agonizes in most tissues including bone. So im confused...

 

[exsttttt]

Researching for hours, closest studies which cover this would be studies on clomiphene (mix of enclomiphene and zuclomiphene). None truly studying growth retardation unless they're popular and known compounds like temox and other serms. Enclomiphene from what I read is largely antagonistic on most tissues, however seems to be positive on bone density, which can possibly infer some agonism to ERα in growth plate cartilage although many factors can contribute to this, and this can be a stretch. Downside to the previous assumption about its possible agonism to ERα within growth plate cartilage is that the studies were using clomiphene where Zuclomiphene can act largely as very bone protective since it generally agonizes in most tissues including bone. So im confused...

most serms appear to agonize er alpha in bone BUT that doesnt mean it will or will not do that in the growth plate, enclo is a trash compound anyway outside of pct

 

[PSLgodBlackPerson]

Researching for hours, closest studies which cover this would be studies on clomiphene (mix of enclomiphene and zuclomiphene). None truly studying growth retardation unless they're popular and known compounds like temox and other serms. Enclomiphene from what I read is largely antagonistic on most tissues, however seems to be positive on bone density, which can possibly infer some agonism to ERα in growth plate cartilage although many factors can contribute to this, and this can be a stretch. Downside to the previous assumption about its possible agonism to ERα within growth plate cartilage is that the studies were using clomiphene where Zuclomiphene can act largely as very bone protective since it generally agonizes in most tissues including bone. So im confused...

bump

 

[PSLgodBlackPerson]

Researching for hours, closest studies which cover this would be studies on clomiphene (mix of enclomiphene and zuclomiphene). None truly studying growth retardation unless they're popular and known compounds like temox and other serms. Enclomiphene from what I read is largely antagonistic on most tissues, however seems to be positive on bone density, which can possibly infer some agonism to ERα in growth plate cartilage although many factors can contribute to this, and this can be a stretch. Downside to the previous assumption about its possible agonism to ERα within growth plate cartilage is that the studies were using clomiphene where Zuclomiphene can act largely as very bone protective since it generally agonizes in most tissues including bone. So im confused...

bumpp

 

[PSLgodBlackPerson]

Researching for hours, closest studies which cover this would be studies on clomiphene (mix of enclomiphene and zuclomiphene). None truly studying growth retardation unless they're popular and known compounds like temox and other serms. Enclomiphene from what I read is largely antagonistic on most tissues, however seems to be positive on bone density, which can possibly infer some agonism to ERα in growth plate cartilage although many factors can contribute to this, and this can be a stretch. Downside to the previous assumption about its possible agonism to ERα within growth plate cartilage is that the studies were using clomiphene where Zuclomiphene can act largely as very bone protective since it generally agonizes in most tissues including bone. So im confused...

bump

 

[lmnopq]

Probly but not as much as zuclomifine. The only serm that can function as an automatic inhibitor is nolvadex