Exposure to Cold Temperatures Can Change Our Gene Expression

[Deleted member 1973]

Exposure to Cold Temperatures Can Change Our Gene Expression and Fat Cells | What is Epigenetics?

Long-term exposure to cold temperatures could actually affect our gene expression and influence our fat cells, a recent study suggests. Research published in Nature Communications offers more evidence on how lifestyle choices and exposure to our environment can dictate the way our genes express...

www.whatisepigenetics.com

An organism’s sympathetic nervous system responds when it’s cold for a long time by releasing adrenaline, eventually reaching white fat if the cold persists. First, the cell begins to change an amino acid in a protein called JMJD1A, which is a histone H3 lysine 9 (H3K9) demethylase. The altered JMJD1A (also known as JHDM2A or KDM3A) then recruits other proteins.

Afterward, the JMJD1A protein complex is recruited to genes that begin thermogenesis. JMJD1A adjusts the epigenetic pattern to turn genes on, making them active. These particular epigenetic alterations transform white fat cells into beige fat cells, which, like brown fat cells, can carry out thermogenesis.

 

[Deleted member 12218]

Should one still expose themselves to cold if they’re trying to adapt to a hot living environment? Such as taking ice baths when you’re trying to get used to Death Valley or just San Diego weather

 

[AsGoodAsItGets]

Should one still expose themselves to cold if they’re trying to adapt to a hot living environment? Such as taking ice baths when you’re trying to get used to Death Valley or just San Diego weather

@Rob Paul'sHeight please answer. Used to take cold showers when I was in EU. Living in India atm, need to pack ice bags to take cold showers jfl