GHK-CU , The Facade And How its Affecting Gains

What Is GHK-Cu

GHK-Cu is a complex consisting of the tripeptide GHK (glycyl-histidyl-lysine) and copper (Cu)

GHK WAS originally described, specifically, as a liver cell growth factor. However, as research continued, experts found that GHK could modulate a number of different cells besides those in the liver.

GHK is naturally found in human saliva, plasma, and urine, but its standard levels are reduced by over half once you reach age 60.

According to experts, GHK has a “strong affinity for copper” and “readily” links up with it to form GHK-Cu. In this form, the peptide complex appears to have strong protective and regenerative properties, leading to its widespread use in cosmetics.s standard levels are reduced by over half once you reach age 60.



What Is GHK-CU "Used For" ?

Most often, you’ll find GHK-Cu copper peptides (usually listed in ingredient lists under the name Copper Tripeptide-1) in various cosmetics, with skin care products being some of the most popular use cases.

GHK-Cu Can...​
  1. Tighten loose skin​
  2. Reverse age-related skin thinning​
  3. Repair the skin’s protective barrier proteins​
  4. Improve skin firmness and elasticity​
  5. Reduce the appearance of fine lines and wrinkles​
  6. Smooth rough skin​
  7. Stimulate wound healing​
  8. Lessen the appearance of photodamage (sun damage), hyperpigmentation, skin spots, lesions.​
  9. Reduce inflammation and damage from free radicals​
  10. Increase hair growth and thickness​


The False Hope



Heres What is shown when you search results



( it has a picture of a before and after )





But Its Really The Results of Plastic Surgery.





Why would they fake results on the internet If its such a PERFECT peptide?




The Hidden Downsides




The Zinc-Copper Relationship.

Copper and zinc share a complex relationship because they compete for absorption in the small intestine; high intake of one can reduce the absorption of the other.
  • Competition: While GHK has a strong affinity for copper and helps regulate its transport, it also interacts with zinc ions. GHK can bind to zinc in an extracellular context and mitigate its toxicity, but the primary way GHK-Cu might indirectly affect zinc levels is through this general absorption competition, if a person had excessive levels of one mineral



Zinc is an essential micronutrient that plays a critical role in the regulation of both testosterone and insulin-like growth factor 1 (IGF-1), with zinc deficiency being linked with both hormones.



Zinc and Testosterone
Zinc is vital for normal male reproductive function and hormone balance.
  • Deficiency reduces testosterone: Studies in both humans and rodents have consistently shown that low zinc levels lead to decreased serum testosterone concentrations.
  • Supplementation can improve levels: For individuals who are zinc-deficient, supplementation has been shown to increase testosterone levels. One study found that men who received 30 mg of zinc per day saw increased free testosterone levels.
  • Mechanism of action: Zinc is necessary for the activity of 5-alpha reductase, an enzyme that converts testosterone into its more potent form, dihydrotestosterone. Zinc deficiency may also impair testosterone synthesis in the Leydig cells and reduce male hormone receptor activity.
  • Baseline levels matter: Zinc supplementation does not appear to raise testosterone levels in men who already have adequate zinc levels




Zinc and IGF-1

Zinc is a key factor in the growth hormone (GH) - IGF-1 axis, which primarily regulates somatic growth and development.

  • Deficiency lowers IGF-1: Zinc deficiency consistently results in lower circulating IGF-1 concentrations, even when caloric intake is adequate.
  • Supplementation increases IGF-1: A systematic review and meta-analysis confirmed that zinc supplementation can elicit significant increases in IGF-1 levels in humans, particularly in children or those with a pre-existing deficiency.
  • Multiple mechanisms: Zinc acts at multiple points in the GH-IGF-1 system:
    • It promotes physiological GH secretion.
    • It is essential for the expression of GH receptor and IGF-1 genes in the liver.
    • It appears to be necessary for the post-receptor signaling pathway of IGF-1, modulating the phosphorylation of the IGF-1 receptor, which is critical for cell division and growth.
  • Age and dosage dependence: The effect of zinc on IGF-1 depends on age, with a more significant impact observed in growing children and preterm infants than in adults. Also, greater increases were seen with dosages of 10 mg/day or less compared to higher doses, suggesting an optimal range.

In summary, maintaining adequate zinc status is crucial for the proper function of the hormonal pathways involving both testosterone and IGF-1.


The primary concern is the zinc/copper balance.
  • Zinc deficiency is associated with impaired testicular function and can affect androgen and GH-IGF-1 metabolism.​
  • Taking GHK-Cu increases copper levels, necessitating a balanced zinc intake to prevent this competition and potential functional zinc deficiency.​
To ensure hormonal balance, it is recommended to take a zinc supplement (e.g. ZInc Glycinate ) then using GHK-Cu, in a dosage that balances the increased copper availability




Hair growth


If your genuinely taking this for the hair side effects , its over, im not explaining enough said.


Overall Opinion

GHK-Cu is a waste of time , a tiktok agenda made it seem like theres 0 downsides and only upwards , it wont fix your brutal ipd , recession or shit hairstyle. Also its really not needed , and by that i mean for the audience what are buying it ( topical or not )

it should be used for healing and tissue , it can help with anti aging to an extent but it wont fix your subhuman acne riddled face when you eat like shit , dont wash your face or your bedding lol. no matter what acne you have it can be fixed , your just not trying hard enough. everyones fixed theirs without trying tiktok shortcuts, your not different.

even so half of you are probably getting it fake jfl


AND EVEN WORSE , half of the ghkcu abusers zinc levels are cooked
so they think their looksmaxxing but their doing the opposite :ROFLMAO:




 
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Reactions: Kazey, Nardicus101, qxdr and 2 others
nah trust bro it'll grow bonemass gandy himself told me that
 
What Is GHK-Cu

GHK-Cu is a complex consisting of the tripeptide GHK (glycyl-histidyl-lysine) and copper (Cu)

GHK WAS originally described, specifically, as a liver cell growth factor. However, as research continued, experts found that GHK could modulate a number of different cells besides those in the liver.

GHK is naturally found in human saliva, plasma, and urine, but its standard levels are reduced by over half once you reach age 60.

According to experts, GHK has a “strong affinity for copper” and “readily” links up with it to form GHK-Cu. In this form, the peptide complex appears to have strong protective and regenerative properties, leading to its widespread use in cosmetics.s standard levels are reduced by over half once you reach age 60.




What Is GHK-CU "Used For" ?

Most often, you’ll find GHK-Cu copper peptides (usually listed in ingredient lists under the name Copper Tripeptide-1) in various cosmetics, with skin care products being some of the most popular use cases.

GHK-Cu Can...​
  1. Tighten loose skin​
  2. Reverse age-related skin thinning​
  3. Repair the skin’s protective barrier proteins​
  4. Improve skin firmness and elasticity​
  5. Reduce the appearance of fine lines and wrinkles​
  6. Smooth rough skin​
  7. Stimulate wound healing​
  8. Lessen the appearance of photodamage (sun damage), hyperpigmentation, skin spots, lesions.​
  9. Reduce inflammation and damage from free radicals​
  10. Increase hair growth and thickness​


The False Hope




Heres What is shown when you search results



( it has a picture of a before and after )







But Its Really The Results of Plastic Surgery.





Why would they fake results on the internet If its such a PERFECT peptide?




The Hidden Downsides




The Zinc-Copper Relationship.

Copper and zinc share a complex relationship because they compete for absorption in the small intestine; high intake of one can reduce the absorption of the other.
  • Competition: While GHK has a strong affinity for copper and helps regulate its transport, it also interacts with zinc ions. GHK can bind to zinc in an extracellular context and mitigate its toxicity, but the primary way GHK-Cu might indirectly affect zinc levels is through this general absorption competition, if a person had excessive levels of one mineral



Zinc is an essential micronutrient that plays a critical role in the regulation of both testosterone and insulin-like growth factor 1 (IGF-1), with zinc deficiency being linked with both hormones.



Zinc and Testosterone
Zinc is vital for normal male reproductive function and hormone balance.
  • Deficiency reduces testosterone: Studies in both humans and rodents have consistently shown that low zinc levels lead to decreased serum testosterone concentrations.
  • Supplementation can improve levels: For individuals who are zinc-deficient, supplementation has been shown to increase testosterone levels. One study found that men who received 30 mg of zinc per day saw increased free testosterone levels.
  • Mechanism of action: Zinc is necessary for the activity of 5-alpha reductase, an enzyme that converts testosterone into its more potent form, dihydrotestosterone. Zinc deficiency may also impair testosterone synthesis in the Leydig cells and reduce male hormone receptor activity.
  • Baseline levels matter: Zinc supplementation does not appear to raise testosterone levels in men who already have adequate zinc levels




Zinc and IGF-1

Zinc is a key factor in the growth hormone (GH) - IGF-1 axis, which primarily regulates somatic growth and development.

  • Deficiency lowers IGF-1: Zinc deficiency consistently results in lower circulating IGF-1 concentrations, even when caloric intake is adequate.
  • Supplementation increases IGF-1: A systematic review and meta-analysis confirmed that zinc supplementation can elicit significant increases in IGF-1 levels in humans, particularly in children or those with a pre-existing deficiency.
  • Multiple mechanisms: Zinc acts at multiple points in the GH-IGF-1 system:
    • It promotes physiological GH secretion.
    • It is essential for the expression of GH receptor and IGF-1 genes in the liver.
    • It appears to be necessary for the post-receptor signaling pathway of IGF-1, modulating the phosphorylation of the IGF-1 receptor, which is critical for cell division and growth.
  • Age and dosage dependence: The effect of zinc on IGF-1 depends on age, with a more significant impact observed in growing children and preterm infants than in adults. Also, greater increases were seen with dosages of 10 mg/day or less compared to higher doses, suggesting an optimal range.

In summary, maintaining adequate zinc status is crucial for the proper function of the hormonal pathways involving both testosterone and IGF-1.


The primary concern is the zinc/copper balance.
  • Zinc deficiency is associated with impaired testicular function and can affect androgen and GH-IGF-1 metabolism.​
  • Taking GHK-Cu increases copper levels, necessitating a balanced zinc intake to prevent this competition and potential functional zinc deficiency.​
To ensure hormonal balance, it is recommended to take a zinc supplement (e.g. ZInc Glycinate ) then using GHK-Cu, in a dosage that balances the increased copper availability




Hair growth


If your genuinely taking this for the hair side effects , its over, im not explaining enough said.


Overall Opinion

GHK-Cu is a waste of time , a tiktok agenda made it seem like theres 0 downsides and only upwards , it wont fix your brutal ipd , recession or shit hairstyle. Also its really not needed , and by that i mean for the audience what are buying it ( topical or not )

it should be used for healing and tissue , it can help with anti aging to an extent but it wont fix your subhuman acne riddled face when you eat like shit , dont wash your face or your bedding lol. no matter what acne you have it can be fixed , your just not trying hard enough. everyones fixed theirs without trying tiktok shortcuts, your not different.

even so half of you are probably getting it fake jfl


AND EVEN WORSE , half of the ghkcu abusers zinc levels are cooked
so they think their looksmaxxing but their doing the opposite :ROFLMAO:




It’s even worse cuz most reconstitute it with BAC instead of PBS water
 
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It’s even worse cuz most reconstitute it with BAC instead of PBS water
facts , without even researching both theyll just go for whatever a tiktok recommended
 
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Fun fact: Zinc capsules are insanely cheap.
 
  • JFL
  • +1
Reactions: Nardicus101 and mcmentalonthemic
I think you're misunderstanding why people are taking GHK CU
it wont fix your brutal ipd , recession or shit hairstyle. Also its really not needed , and by that i mean for the audience what are buying it ( topical or not )
Nobody is taking it for IPD, or Recession, they are taking it, and only taking it, for better MISC
Better health indicators in the skin and hair, for anti aging, for clear skin, for a high collagen prettyboy look

Zinc is necessary for the activity of 5-alpha reductase, an enzyme that converts testosterone into its more potent form, dihydrotestosterone.
Bad point since there is alot of people in this forum who literally take FInasteride and Dutasteride, DiHydroTestosterone inhibitors
It's literally forum consensus that DHT is bad
Also, all of these downsides, can't they just be.. overriden by supplementing zinc?

Here you admit everything GHK-CU can do..



GHK-Cu Can...​
  1. Tighten loose skin​
  2. Reverse age-related skin thinning​
  3. Repair the skin’s protective barrier proteins​
  4. Improve skin firmness and elasticity​
  5. Reduce the appearance of fine lines and wrinkles​
  6. Smooth rough skin​
  7. Stimulate wound healing​
  8. Lessen the appearance of photodamage (sun damage), hyperpigmentation, skin spots, lesions.​
  9. Reduce inflammation and damage from free radicals​
  10. Increase hair growth and thickness​
Then you list a bunch of muh downsides that you admit can be overriden with Zinc supplementation

I was a bit worried ,I was going to hop on GHK CU and thought it was going to be a high Knowledge thread showcasing reasons why you shouldn't take it but all it seems is this

- Don't take GHK CU unless you're supplementing Zinc

Also...


The False Hope

Heres What is shown when you search results


( it has a picture of a before and after )


But Its Really The Results of Plastic Surgery.


Why would they fake results on the internet If its such a PERFECT peptide?

Second link:
1763943469864

It literally shows Injection surgery as one of the options, this before and after could be showcasing Dr. Ali Soueid's injection surgery results, lol.



TLDR: THE ONLY THING THIS THREAD PROVES IS TO TAKE GHK CU WITH ZINC, LOL.
 
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There is more nuance to this with some stuff you should of included:

I agree heavy with the zinc part

1. you should factored in the time it takes to see results
2. you also should of factored in the difference when PBS in reconstituted with it due to PH level
3. How the topical solutions dont work because most people are using a topical solution that is either too weak in terms of concentration
4. and also in terms of penetrating the skin which could be where micro needling and a stonger solution paired with it works.

I talk about the concentration % strength more on here when debating which one you should go with:
I also have this added in routine which gave me good results that I will be posting soon:


Overall decent thread tho there are some threads that talk more about why people think its useless like this one here:



Most people are not seeing result cause there either not using It right, or they are not using a strong enough solution.
 
Last edited:
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Reactions: replentrrr and mcmentalonthemic
I think you're misunderstanding why people are taking GHK CU

Nobody is taking it for IPD, or Recession, they are taking it, and only taking it, for better MISC
Better health indicators in the skin and hair, for anti aging, for clear skin, for a high collagen prettyboy look

Bad point since there is alot of people in this forum who literally take FInasteride and Dutasteride, DiHydroTestosterone inhibitors
It's literally forum consensus that DHT is bad
Also, all of these downsides, can't they just be.. overriden by supplementing zinc?

Here you admit everything GHK-CU can do..

Then you list a bunch of muh downsides that you admit can be overriden with Zinc supplementation

I was a bit worried ,I was going to hop on GHK CU and thought it was going to be a high Knowledge thread showcasing reasons why you shouldn't take it but all it seems is this

- Don't take GHK CU unless you're supplementing Zinc

Also...

Second link:
View attachment 4357520
It literally shows Injection surgery as one of the options, this before and after could be showcasing Dr. Ali Soueid's injection surgery results, lol.



TLDR: THE ONLY THING THIS THREAD PROVES IS TO TAKE GHK CU WITH ZINC, LOL.
Literally he's a grey so he has a lot to learn
 
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Reactions: mcmentalonthemic
Holy cope. Ifu are deficient in zinc as a LOOKSMAXER you need to cut off your penis and shoot yourself. As a looksmaxer, zinc should be the easiest nutrient to get because of red meat and protein sources. If you are eating a clean diet and therefore getting ur nutrients then ur chill. U are retarded. U can also supplement
 
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Reactions: Nardicus101
There is more nuance to this with some stuff you should of included:

I agree heavy with the zinc part

1. you should factored in the time it takes to see results
2. you also should of factored in the difference when PBS in reconstituted with it due to PH level
3. How the topical solutions dont work because most people are using a topical solution that is either too weak in terms of concentration
4. and also in terms of penetrating the skin which could be where micro needling and a stonger solution paired with it works.

I talk about the concentration % strength more on here when debating which one you should go with:
I also have this added in routine which gave me good results that I will be posting soon:


Overall decent thread tho there are some threads that talk more about why people think its useless like this one here:



Most people are not seeing result cause there either not using It right, or they are not using a strong enough solution.
Do you know any reliable ones that aren’t too expensive that are around 3%. 30% seems way to high.
 
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Do you know any reliable ones that aren’t too expensive that are around 3%. 30% seems way to high.
Yes it is high and than is a good thing

Thats why you buy A hyaluronic acid and use that to dilute it so you get to pick your concentration
 
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Do you know any reliable ones that aren’t too expensive that are around 3%. 30% seems way to high.
if your using the GHK-CU serum that is 30% make sure you dilute it with hyaluronic acid as 30% is super fucking strong but when diluted you basically get to pick your strength that you want which is way better than buying these water products.
 
I think you're misunderstanding why people are taking GHK CU

Nobody is taking it for IPD, or Recession, they are taking it, and only taking it, for better MISC
Better health indicators in the skin and hair, for anti aging, for clear skin, for a high collagen prettyboy look

Bad point since there is alot of people in this forum who literally take FInasteride and Dutasteride, DiHydroTestosterone inhibitors
It's literally forum consensus that DHT is bad
Also, all of these downsides, can't they just be.. overriden by supplementing zinc?

Here you admit everything GHK-CU can do..

Then you list a bunch of muh downsides that you admit can be overriden with Zinc supplementation

I was a bit worried ,I was going to hop on GHK CU and thought it was going to be a high Knowledge thread showcasing reasons why you shouldn't take it but all it seems is this

- Don't take GHK CU unless you're supplementing Zinc

Also...

Second link:
View attachment 4357520
It literally shows Injection surgery as one of the options, this before and after could be showcasing Dr. Ali Soueid's injection surgery results, lol.



TLDR: THE ONLY THING THIS THREAD PROVES IS TO TAKE GHK CU WITH ZINC, LOL.
The ipd and recession was a joke ngl , and we know the benefits of ghkcu , but the point of the thread is no one is using it correctly or for the right reasons.

and yes all of this can be fixed with balancing zinc , but are people actually doing this?
 

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