Good supplements for puberty 14yo?

probablydeadby21

probablydeadby21

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title explains
 
HGH
 
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  • Ugh..
  • JFL
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why will you probably be dead by 21
 
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probablydeadby21 said:
title explains
Click to expand...
  • Estrogen signaling (ERα)
  • FGFR3 signaling (brake on proliferation + maturation control)
  • Wnt/β-catenin (ossification / bone replacement)
  • BMP signaling (hypertrophy + bone formation)
  • Notch (timing of maturation)
 
  • Love it
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itsoverformr said:
  • Estrogen signaling (ERα)
  • FGFR3 signaling (brake on proliferation + maturation control)
  • Wnt/β-catenin (ossification / bone replacement)
  • BMP signaling (hypertrophy + bone formation)
  • Notch (timing of maturation)
Click to expand...
Inhibit theese mb
 
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probablydeadby21 said:
why? what he said is useless or what?
Click to expand...
Yes hes retarded as i said if you want to pubertmax do atleast 100mg test aromatase inhibtor and inhibit theese for height growth
  • Estrogen signaling (ERα)
  • FGFR3 signaling (brake on proliferation + maturation control)
  • Wnt/β-catenin (ossification / bone replacement)
  • BMP signaling (hypertrophy + bone formation)
  • Notch (timing of maturation)

Activate
  • GH–IGF-1
  • CNP–NPR2


FInd a way to inhibit somatostatin
 
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what are
probablydeadby21 said:
why? what he said is useless or what?
Click to expand...
its just ppl who believe peptides and all that shit is their fucking god, my comment isnt exactly informational but do your research. zinc for example supports healthy testosterone production, not to the extent where injecting will make u massive in the gym, but to the extent you're happy and confident in life and feel good about your health
 
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noahhokkk said:
vit d3 and k2
zinc
vitamin c (regulating cortisol)
askwaganda (prevents cortisol spikes)
cholesterol from diet (eggs)
Click to expand...
Magnesium, creatine, vitamin b-12 , and omega-3 too.
 
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hihelp said:
Magnesium, creatine, vitamin b-12 , and omega-3 too.
Click to expand...
yes bro, theres quite a few i missed out, just cant be bothered to deal with ppl with no common sense into what ppl r asking and just saying ur a retard because u didnt suggest a fucking chinese chemical, appreciate the reply bro
 
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noahhokkk said:
yes bro, theres quite a few i missed out, just cant be bothered to deal with ppl with no common sense into what ppl r asking and just saying ur a retard because u didnt suggest a fucking chinese chemical, appreciate the reply bro
Click to expand...
Yes but we all start somewhere
 
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HGH, if you truly understood how brutal the heightpill is, you'll find a way to get your hands on it
 
7empest said:
HGH, if you truly understood how brutal the heightpill is, you'll find a way to get your hands on it
Click to expand...
Fucking idiot hgh doesnt make you taller :forcedsmile:
 
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inject pee
 
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  • Woah
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GoyLite said:
alr read, debunked
Click to expand...
How, show, you have studies showing HGH improved final adult height on people with no growth hormone deficency or ISS?
 
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terlound said:
How, show, you have studies showing HGH improved final adult height on people with no growth hormone deficency or ISS?
Click to expand...
yup heres some:

https://pubmed.ncbi.nlm.nih.gov/15240584/
pubmed.ncbi.nlm.nih.gov

Growth hormone (GH) treatment to final height in children with idiopathic short stature: evidence for a dose effect - PubMed

GH treatment dose-dependently increases height velocity and final height in children with idiopathic short stature.
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov

Effect of growth hormone therapy on height in children with idiopathic short stature: a meta-analysis - PubMed

Treatment with GH results in short-term increases in growth for children with idiopathic short stature, and long-term GH can increase adult height. These results are fundamental to decisions about GH use and raise questions about the goals of treatment. Use of GH for idiopathic short stature in...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

if thats not enough, lmk i can send more.
 
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GoyLite said:
yup heres some:

https://pubmed.ncbi.nlm.nih.gov/15240584/
pubmed.ncbi.nlm.nih.gov

Growth hormone (GH) treatment to final height in children with idiopathic short stature: evidence for a dose effect - PubMed

GH treatment dose-dependently increases height velocity and final height in children with idiopathic short stature.
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov

Disintermediating your friends: How online dating in the United States displaces other ways of meeting - PubMed

We present data from a nationally representative 2017 survey of American adults. For heterosexual couples in the United States, meeting online has become the most popular way couples meet, eclipsing meeting through friends for the first time around 2013. Moreover, among the couples who meet...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov

Effect of growth hormone therapy on height in children with idiopathic short stature: a meta-analysis - PubMed

Treatment with GH results in short-term increases in growth for children with idiopathic short stature, and long-term GH can increase adult height. These results are fundamental to decisions about GH use and raise questions about the goals of treatment. Use of GH for idiopathic short stature in...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

if thats not enough, lmk i can send more.
Click to expand...
oh my god they all have ISS bro im asking for healthy people mate :forcedsmile::forcedsmile::forcedsmile:
 
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terlound said:
oh my god they all have ISS bro im asking for healthy people mate :forcedsmile::forcedsmile::forcedsmile:
Click to expand...
oh shoot mb i didnt see that you said iss i had some saved, i prob have a few without gimme a moment.

rep me if were gonna keep back and forthing.
 
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GoyLite said:
oh shoot mb i didnt see that you said iss i had some saved, i prob have a few without gimme a moment.

rep me if were gonna keep back and forthing.
Click to expand...
i have been
 
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GoyLite said:
yup heres some:

https://pubmed.ncbi.nlm.nih.gov/15240584/
pubmed.ncbi.nlm.nih.gov

Growth hormone (GH) treatment to final height in children with idiopathic short stature: evidence for a dose effect - PubMed

GH treatment dose-dependently increases height velocity and final height in children with idiopathic short stature.
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov

Effect of growth hormone therapy on height in children with idiopathic short stature: a meta-analysis - PubMed

Treatment with GH results in short-term increases in growth for children with idiopathic short stature, and long-term GH can increase adult height. These results are fundamental to decisions about GH use and raise questions about the goals of treatment. Use of GH for idiopathic short stature in...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

if thats not enough, lmk i can send more.
Click to expand...
Shhh no point into arguing with niggas like that, they will learn the hard way, when it’s too late to learn:feelsuhh:
 
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AtrophicPyra said:
Shhh no point into arguing with niggas like that, they will learn the hard way, when it’s too late to learn:feelsuhh:
Click to expand...
agreed but im still gonna make my point
 
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terlound said:
How, show, you have studies showing HGH improved final adult height on people with no growth hormone deficency or ISS?
Click to expand...
https://pubmed.ncbi.nlm.nih.gov/8691923/
pubmed.ncbi.nlm.nih.gov

Randomised trial of growth hormone in short normal girls - PubMed

Growth-hormone therapy effectively increased height SD score among short normal girls started on treatment in early to mid childhood, with no untoward effect on pubertal progression.
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov

Effectiveness of growth hormone (GH) therapy in GH-deficient children and non-GH-deficient short children - PubMed

The growth response during short-term growth hormone (GH) treatment was evaluated in eight prepubertal non-GH-deficient (non-GHD) children and compared with six prepubertal GH-deficient (GHD) patients. Standard doses of GH can improve growth rate in GHD and in some non-GHD patients. In neither...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Growth hormone therapy isn't a new or experimental concept its FDA-approved for decades with a ton of research behind it in GHD and ISS populations, and the mechanisms are well understood. What's less documented is its use in children without those diagnoses, and that's not because it doesn't work in them. It's because ethics boards are hesitant to approve hormonal interventions in healthy kids and pharmaceutical companies have no incentive to fund research outside of approved indications. The studies that do exist still show real measurable increases in final adult height even in children with confirmed normal GH levels. The biology supports this too since GH signaling at the growth plate is dose responsive, not a switch that only flips on in the presence of a deficiency. The effect is probably smaller when starting from a normal baseline, but its not gpnna just disappear because someone lacks a diagnosis.

@Sycophant what you think?
also tag anyone
 
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GoyLite said:
https://pubmed.ncbi.nlm.nih.gov/8691923/
pubmed.ncbi.nlm.nih.gov

Randomised trial of growth hormone in short normal girls - PubMed

Growth-hormone therapy effectively increased height SD score among short normal girls started on treatment in early to mid childhood, with no untoward effect on pubertal progression.
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov

Effectiveness of growth hormone (GH) therapy in GH-deficient children and non-GH-deficient short children - PubMed

The growth response during short-term growth hormone (GH) treatment was evaluated in eight prepubertal non-GH-deficient (non-GHD) children and compared with six prepubertal GH-deficient (GHD) patients. Standard doses of GH can improve growth rate in GHD and in some non-GHD patients. In neither...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Growth hormone therapy isn't a new or experimental concept its FDA-approved for decades with a ton of research behind it in GHD and ISS populations, and the mechanisms are well understood. What's less documented is its use in children without those diagnoses, and that's not because it doesn't work in them. It's because ethics boards are hesitant to approve hormonal interventions in healthy kids and pharmaceutical companies have no incentive to fund research outside of approved indications. The studies that do exist still show real measurable increases in final adult height even in children with confirmed normal GH levels. The biology supports this too since GH signaling at the growth plate is dose responsive, not a switch that only flips on in the presence of a deficiency. The effect is probably smaller when starting from a normal baseline, but its not gpnna just disappear because someone lacks a diagnosis.
Click to expand...
1781236983447

1781237024130

this refers to ISS btw :forcedsmile:
 
GoyLite said:
not true, short doesn't mean iss, just like how a guy that is 5'5 isnt ghd or having iss hes just short.
Click to expand...
ill give you the benefit of the doubt, sure okay

but the sample size for both is 8 people. and the control group was 6 are we serious bro :forcedsmile:

this is not conclusive at all
 
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terlound said:
ill give you the benefit of the doubt, sure okay

but the sample size for both is 8 people. and the control group was 6 are we serious bro :forcedsmile:

this is not conclusive at all
Click to expand...
again, It's because ethics boards are hesitant to approve hormonal interventions in healthy kids and pharmaceutical companies have no incentive to fund research outside of approved indications.
 
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GoyLite said:
if you would direct your eyes just below both of them they say "short-normal" meaning without a disorder, iss or any sort of deficiency
Click to expand...
most scientific literature requires a sample size of 30-50, however I understand how it's very difficult to get these numbers due to the controversial nature of these treatments on otherwise healthy people.
 
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GoyLite said:
again, It's because ethics boards are hesitant to approve hormonal interventions in healthy kids and pharmaceutical companies have no incentive to fund research outside of approved indications.
Click to expand...
Well there are studies done like that

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed

both of these are flawed though, but generally they arent "too" bad
 
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GoyLite said:
Isn’t this proving my point further?
Click to expand...
All those studies conclude that HGH on people with non GH deficiencies, final adult height slightly decreases or stays the same
 
terlound said:
All those studies conclude that HGH on people with non GH deficiencies, final adult height slightly decreases or stays the same
Click to expand...
Sorry for late response I’m on vacation but they literally all say that it’s >2cm taller
 
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