Hair Thinning!!

[fake.molecule96]

Hey guys, I’m 18 and recently noticed some hair thinning, especially around the Hairline/temple and sides area. My hairline has always been a bit high, so I’m not sure if it’s normal maturation or actual thinning. I also notice some hair fall while applying oil or shampooing. I'm using minoxidil 5% from one week and sometimes rosemary oil too (ts from 2 months ig), what else can i do? And also from a recent blood work i got to know that I'm low on vitamin B12
The levels are:
Vitamin B12- 258 pg/ml (took supplements for 2 months
Vitamin D- 34 ng/dl (i took supplements for 5 months, earlier it was 12 ng/dl)
Ferritin- 48.4 ng/ml
(My father side hairs are good but my mother side uncles went bald in their early 30s)

 

[Pay]

minox from one week? what do you mean-

 

[monk321]

over buddy boyo , consider dut oral min topical dut fin min latanoprost , Exosome Prp therapy , microneedling daily 1.5mm , ketaconozol shampoo , tb bpc ghkcu ahkcu kpv ditrectly injected in ur scalp , if not enough you can always cut your balls before you become a completely balding subhuman

 

[fake.molecule96]

minox from one week? what do you mean-

Yea I've been using topical minoxidil to treat my hair thinning from past one week, before that i was only using rosemary essential oil + coconut oil, I've been noticing thinning frm 5-6 months and i have always procrastinated ... I've seen lot of people in youtube comment section talking about that minoxidil doesn't work, have side effects this n that and that makes me question about the treatment

 

[fake.molecule96]

over buddy boyo , consider dut oral min topical dut fin min latanoprost , Exosome Prp therapy , microneedling daily 1.5mm , ketaconozol shampoo , tb bpc ghkcu ahkcu kpv ditrectly injected in ur scalp , if not enough you can always cut your balls before you become a completely balding subhuman

Tf bro jss gave all the hairloss drugs, but alr lemme see how minoxidil works at first

 

[monk321]

Tf bro jss gave all the hairloss drugs, but alr lemme see how minoxidil works at first

norwood reaper jfling at you with only minox

 

[AstroSky]

If you wait just a little bit, I’ll be coming out with a liposomal RU58841, dutasteride, and latanoprost hair-loss gel/solution that, based on my research, may outperform most other methods of application.

The key here is the liposomal delivery. The goal is to help RU58841 and dutasteride stay more localized to the scalp and sebaceous/follicle area instead of going systemic like harsh ethanol/PG-based solutions can. I’ve been working on this for a while and have also been looking for proper suppliers for latanoprost, which I think is a highly underrated prostaglandin analogue. It has evidence for hair growth and may work through a different pathway than minoxidil, without the same “minoxidil dependency” issue people worry about. The only problem is that latanoprost is straight-up expensive to source. Not enough products on the market contain it, and when you do find it, it’s usually only through compounding pharmacies.

Once I get the liposome system properly made and dialed in, I’ll have more info. It takes its own set of equipment and testing to do correctly. Ethanol-based solutions and PG-heavy solutions can cause too much systemic absorption for what I’m trying to create. My goal is to make a product that minimizes side effects as much as possible while tackling at least four different vectors of the hair-loss process.

Too many products only focus on one pathway. DHT is the main driver for male-pattern hair loss, but it’s not the only reason hair weakens and falls out. Inflammation, follicle weakening, poor scalp environment, and mitochondrial dysfunction can all play a role too. That’s why I’m also looking at adding CoQ10 and melatonin to support those angles, since both have research behind them for oxidative stress, mitochondrial support, and hair-related pathways.

I can’t fully target stem-cell stimulation yet ....that would be better suited for something like PP405. buit theres not enough data on that yet and its hard to actually get. but for the DHT/androgen side of hair loss and actually helping stop the hair from falling out, I truly believe liposome-based hair-loss topicals are the direction the industry needs to go.

 

[AstroSky]

Hey guys, I’m 18 and recently noticed some hair thinning, especially around the Hairline/temple and sides area. My hairline has always been a bit high, so I’m not sure if it’s normal maturation or actual thinning. I also notice some hair fall while applying oil or shampooing. I'm using minoxidil 5% from one week and sometimes rosemary oil too (ts from 2 months ig), what else can i do? And also from a recent blood work i got to know that I'm low on vitamin B12
The levels are:
Vitamin B12- 258 pg/ml (took supplements for 2 months
Vitamin D- 34 ng/dl (i took supplements for 5 months, earlier it was 12 ng/dl)
Ferritin- 48.4 ng/ml

One thing people need to understand is that minoxidil does not actually fix the root cause of male-pattern hair loss. It can help keep hair in the anagen/growth phase longer and improve growth, but if scalp DHT and androgen signaling are still active, the follicles can continue to miniaturize over time....so whatever your doing right now will not fix your hairloss if you are indeed losing hair.

Personally, I do not believe in crushing systemic DHT unless absolutely necessary. If you’re going to target the DHT pathway, I think it makes more sense to focus on a topical/local approach. DHT is important for neurosteroid production, mood, libido, mental health, and other pathways, so completely driving it into the ground can potentially cause issues.

That’s why I’m more interested in targeted scalp solutions...controlling the androgen/DHT pressure where it matters, without trying to wipe it out throughout the entire body.

 

[fake.molecule96]

bro got the norwood reaper spectating my scalp in 4k

norwood reaper jfling at you with only minox

 

[AstroSky]

Hey guys, I’m 18 and recently noticed some hair thinning, especially around the Hairline/temple and sides area. My hairline has always been a bit high, so I’m not sure if it’s normal maturation or actual thinning. I also notice some hair fall while applying oil or shampooing. I'm using minoxidil 5% from one week and sometimes rosemary oil too (ts from 2 months ig), what else can i do? And also from a recent blood work i got to know that I'm low on vitamin B12
The levels are:
Vitamin B12- 258 pg/ml (took supplements for 2 months
Vitamin D- 34 ng/dl (i took supplements for 5 months, earlier it was 12 ng/dl)
Ferritin- 48.4 ng/ml
(My father side hairs are good but my mother side uncles went bald in their early 30s)

based on what im seeing your hair looks very healthy right now and your top crown is strong, i have no clue about your frontal area and if you just have a larger than avg forhead or not, but from your top crown you are not currently norwooding at all. your hair is thick and has good quality to it. you are def within early early early stages of whatever hairloss could be going on. dont worry so hard right now but do keep an eye out. stressing is one way to make it worse

 

[ascensionissoon]

One thing people need to understand is that minoxidil does not actually fix the root cause of male-pattern hair loss. It can help keep hair in the anagen/growth phase longer and improve growth, but if scalp DHT and androgen signaling are still active, the follicles can continue to miniaturize over time....so whatever your doing right now will not fix your hairloss if you are indeed losing hair.

Personally, I do not believe in crushing systemic DHT unless absolutely necessary. If you’re going to target the DHT pathway, I think it makes more sense to focus on a topical/local approach. DHT is important for neurosteroid production, mood, libido, mental health, and other pathways, so completely driving it into the ground can potentially cause issues.

That’s why I’m more interested in targeted scalp solutions...controlling the androgen/DHT pressure where it matters, without trying to wipe it out throughout the entire body.

Excited for this thread

 

[bratex2213]

Hey guys, I’m 18 and recently noticed some hair thinning, especially around the Hairline/temple and sides area. My hairline has always been a bit high, so I’m not sure if it’s normal maturation or actual thinning. I also notice some hair fall while applying oil or shampooing. I'm using minoxidil 5% from one week and sometimes rosemary oil too (ts from 2 months ig), what else can i do? And also from a recent blood work i got to know that I'm low on vitamin B12
The levels are:
Vitamin B12- 258 pg/ml (took supplements for 2 months
Vitamin D- 34 ng/dl (i took supplements for 5 months, earlier it was 12 ng/dl)
Ferritin- 48.4 ng/ml
(My father side hairs are good but my mother side uncles went bald in their early 30s)

listen bro, minoxidil alone is not enough, my hair was worse than u and now I hair mog most my class thats the protocol : duasteride 2,5mg a day, minoxidil twice a day, ru58841 at night , and if u can find spironolactone cream use it too .

 

[fake.molecule96]

If you wait just a little bit, I’ll be coming out with a liposomal RU58841, dutasteride, and latanoprost hair-loss gel/solution that, based on my research, may outperform most other methods of application.

The key here is the liposomal delivery. The goal is to help RU58841 and dutasteride stay more localized to the scalp and sebaceous/follicle area instead of going systemic like harsh ethanol/PG-based solutions can. I’ve been working on this for a while and have also been looking for proper suppliers for latanoprost, which I think is a highly underrated prostaglandin analogue. It has evidence for hair growth and may work through a different pathway than minoxidil, without the same “minoxidil dependency” issue people worry about. The only problem is that latanoprost is straight-up expensive to source. Not enough products on the market contain it, and when you do find it, it’s usually only through compounding pharmacies.

Once I get the liposome system properly made and dialed in, I’ll have more info. It takes its own set of equipment and testing to do correctly. Ethanol-based solutions and PG-heavy solutions can cause too much systemic absorption for what I’m trying to create. My goal is to make a product that minimizes side effects as much as possible while tackling at least four different vectors of the hair-loss process.

Too many products only focus on one pathway. DHT is the main driver for male-pattern hair loss, but it’s not the only reason hair weakens and falls out. Inflammation, follicle weakening, poor scalp environment, and mitochondrial dysfunction can all play a role too. That’s why I’m also looking at adding CoQ10 and melatonin to support those angles, since both have research behind them for oxidative stress, mitochondrial support, and hair-related pathways.

I can’t fully target stem-cell stimulation yet ....that would be better suited for something like PP405. buit theres not enough data on that yet and its hard to actually get. but for the DHT/androgen side of hair loss and actually helping stop the hair from falling out, I truly believe liposome-based hair-loss topicals are the direction the industry needs to go.

respect the knowledge dump bro i’m just a bit hesitant to go too crazy with treatments rn since i’m still 18, my doc told me that its very early to take duastride and finastride, and you are talking bout sum powerful anti-androgens

 

[Prøphet]

If you wait just a little bit, I’ll be coming out with a liposomal RU58841, dutasteride, and latanoprost hair-loss gel/solution that, based on my research, may outperform most other methods of application.

The key here is the liposomal delivery. The goal is to help RU58841 and dutasteride stay more localized to the scalp and sebaceous/follicle area instead of going systemic like harsh ethanol/PG-based solutions can. I’ve been working on this for a while and have also been looking for proper suppliers for latanoprost, which I think is a highly underrated prostaglandin analogue. It has evidence for hair growth and may work through a different pathway than minoxidil, without the same “minoxidil dependency” issue people worry about. The only problem is that latanoprost is straight-up expensive to source. Not enough products on the market contain it, and when you do find it, it’s usually only through compounding pharmacies.

Once I get the liposome system properly made and dialed in, I’ll have more info. It takes its own set of equipment and testing to do correctly. Ethanol-based solutions and PG-heavy solutions can cause too much systemic absorption for what I’m trying to create. My goal is to make a product that minimizes side effects as much as possible while tackling at least four different vectors of the hair-loss process.

Too many products only focus on one pathway. DHT is the main driver for male-pattern hair loss, but it’s not the only reason hair weakens and falls out. Inflammation, follicle weakening, poor scalp environment, and mitochondrial dysfunction can all play a role too. That’s why I’m also looking at adding CoQ10 and melatonin to support those angles, since both have research behind them for oxidative stress, mitochondrial support, and hair-related pathways.

I can’t fully target stem-cell stimulation yet ....that would be better suited for something like PP405. buit theres not enough data on that yet and its hard to actually get. but for the DHT/androgen side of hair loss and actually helping stop the hair from falling out, I truly believe liposome-based hair-loss topicals are the direction the industry needs to go.

Lifefuel man I cannot tolerate oral 5ari or even ethanol topical for shit so I would definitely buy that

Out of curiosity what do you think of cb 03 01 breezula? It looks promising to me tbh hopefully they release it soon

 

[AstroSky]

respect the knowledge dump bro i’m just a bit hesitant to go too crazy with treatments rn since i’m still 18, my doc told me that its very early to take duastride and finastride, and you are talking bout sum powerful anti-androgens

i would be hesitant too. your 18, so it would not be wise to drop the kitchen sink on your self right now. but if it does get worse try hard not to just pop fin and dut pills as most recommend. focus on topical

 

[Finncelchud]

Apply topical minoxidil and ru58841 daily start using ketoconazole shampoo 3x times a week, micro needle you scalp 1x every week.

If this doesen't work start using dutasteride or finasteride every day

 

[Finncelchud]

over buddy boyo , consider dut oral min topical dut fin min latanoprost , Exosome Prp therapy , microneedling daily 1.5mm , ketaconozol shampoo , tb bpc ghkcu ahkcu kpv ditrectly injected in ur scalp , if not enough you can always cut your balls before you become a completely balding subhuman

microneedling daily will do more harm than good

 

[monk321]

microneedling daily will do more harm than good

was trolling about that should be weekly but i stopped doing it , 0 difference even after a year

 

[AstroSky]

Lifefuel man I cannot tolerate oral 5ari or even ethanol topical for shit so I would definitely buy that

Out of curiosity what do you think of cb 03 01 breezula? It looks promising to me tbh hopefully they release it soon

Most of these products all basically do similar things in the end. RU58841 has some of the strongest androgen receptor blocking potential by far. The only problem is there are basically no proper human trials, and a lot of people believe it could cause internal issues long-term if too much goes systemic.

I believe CB-03-01 could be good, and I do think it has its place, but I also think RU58841 and its ability to directly block the androgen signal is much stronger in theory. So if I want to help people use it in the smartest way possible, making it as non-systemic and scalp-localized as possible is the best way to approach it.

In the name of research, there was once an esterified version of RU58841 called RU58841 Myristate, also known as RUM. In theory, this was probably one of the closest things to a “holy grail” topical anti-androgen concept, but it never really took off.

Finding raw RUM is almost impossible. There is basically one guy who sells it, and it is insanely expensive. But if I can get my hands on a larger supply, I would seriously consider switching to that or eventually making a version with it, because it fits the exact direction I’m trying to go with liposomal/topical delivery.

RUM is different from normal RU58841 because it has a fatty-acid chain attached to it. That fatty chain makes it more lipid-loving, meaning it should bind better into the oil/lipid parts of the scalp, sebaceous glands, and follicle area.

That matters because the goal is not to just dump RU onto the scalp and hope for the best. The goal is to make the RU stay where it is actually needed.

Regular RU58841 is already strong, but the issue is delivery. If you use a harsh ethanol/PG solution, you may get more systemic absorption than you want. That is where people start worrying about side effects.

RUM was designed more like a slow-release prodrug. It sits in the lipid environment better, then skin enzymes can slowly convert it back into active RU58841 locally. So instead of getting a fast spike, the idea is more local residence, slower release, and more targeted scalp activity. ....but finding the raws is impossible for this one. must be a one off lab project someone did and now he just sells whats left from 2005.

 

[Finncelchud]

Most of these products all basically do similar things in the end. RU58841 has some of the strongest androgen receptor blocking potential by far. The only problem is there are basically no proper human trials, and a lot of people believe it could cause internal issues long-term if too much goes systemic.

I believe CB-03-01 could be good, and I do think it has its place, but I also think RU58841 and its ability to directly block the androgen signal is much stronger in theory. So if I want to help people use it in the smartest way possible, making it as non-systemic and scalp-localized as possible is the best way to approach it.

In the name of research, there was once an esterified version of RU58841 called RU58841 Myristate, also known as RUM. In theory, this was probably one of the closest things to a “holy grail” topical anti-androgen concept, but it never really took off.

Finding raw RUM is almost impossible. There is basically one guy who sells it, and it is insanely expensive. But if I can get my hands on a larger supply, I would seriously consider switching to that or eventually making a version with it, because it fits the exact direction I’m trying to go with liposomal/topical delivery.

RUM is different from normal RU58841 because it has a fatty-acid chain attached to it. That fatty chain makes it more lipid-loving, meaning it should bind better into the oil/lipid parts of the scalp, sebaceous glands, and follicle area.

That matters because the goal is not to just dump RU onto the scalp and hope for the best. The goal is to make the RU stay where it is actually needed.

Regular RU58841 is already strong, but the issue is delivery. If you use a harsh ethanol/PG solution, you may get more systemic absorption than you want. That is where people start worrying about side effects.

RUM was designed more like a slow-release prodrug. It sits in the lipid environment better, then skin enzymes can slowly convert it back into active RU58841 locally. So instead of getting a fast spike, the idea is more local residence, slower release, and more targeted scalp activity. ....but finding the raws is impossible for this one. must be a one off lab project someone did and now he just sells whats left from 2005.

What are the systemic effects of ru58841?

 

[fake.molecule96]

based on what im seeing your hair looks very healthy right now and your top crown is strong, i have no clue about your frontal area and if you just have a larger than avg forhead or not, but from your top crown you are not currently norwooding at all. your hair is thick and has good quality to it. you are def within early early early stages of whatever hairloss could be going on. dont worry so hard right now but do keep an eye out. stressing is one way to make it worse

appreciate the detailed response bro that genuinely made me less stressed about it after knowing that I'm in early stages and dass what my doc also said. imma keep an eye on it and try my best, wtv i can do, wtv the doc suggests

 

[Finncelchud]

appreciate the detailed response bro that genuinely made me less stressed about it after knowing that I'm in early stages and dass what my doc also said. imma keep an eye on it and try my best, wtv i can do, wtv the doc suggests

Yeah, I didin't notice any hairloss on your head, but it is still good to do preventitive mesures, even if you dont have any hairloss yet

 

[fake.molecule96]

Apply topical minoxidil and ru58841 daily start using ketoconazole shampoo 3x times a week, micro needle you scalp 1x every week.

If this doesen't work start using dutasteride or finasteride every day

Yea I'm applying minoxidil 1ml twice a day, i read about ru58841, its like not really clinically proven but okay I'll look for it if i get some more information... I am thinking of derma rolling, dass fine weekly.. True datt if all this doesn't work and worsen the situation, imma hop on fin later

 

[fake.molecule96]

Yeah, I didin't notice any hairloss on your head, but it is still good to do preventitive mesures, even if you dont have any hairloss yet

Yea prevention is better than cure

 

[AstroSky]

What are the systemic effects of ru58841?

Honestly, it’s hard to say with RU ....

A lot of guys who use RU are already super paranoid about hair loss, hormones, side effects, and anything they put on their body. So when people on forums say RU is “poison” or “dangerous,” I’d take it with a grain of salt. and they often seem to be a bit mentally ill too,


From what we actually know, RU doesn’t really have solid long-term human trials. That’s the main issue. But there also isn’t strong proof that it’s harmed people long-term either. Most of what you hear is anecdotal ...people saying they felt weird, had chest tightness, heart sensations, anxiety, or just “felt off.” And that’s hard to judge because those symptoms can come from a million different things, especially when people are already anxious about what they’re taking.

I personally use RU and get zero side effects, but that doesn’t mean everyone will respond the same.

 

[Finncelchud]

Honestly, it’s hard to say with RU ....

A lot of guys who use RU are already super paranoid about hair loss, hormones, side effects, and anything they put on their body. So when people on forums say RU is “poison” or “dangerous,” I’d take it with a grain of salt. and they often seem to be a bit mentally ill too,


From what we actually know, RU doesn’t really have solid long-term human trials. That’s the main issue. But there also isn’t strong proof that it’s harmed people long-term either. Most of what you hear is anecdotal ...people saying they felt weird, had chest tightness, heart sensations, anxiety, or just “felt off.” And that’s hard to judge because those symptoms can come from a million different things, especially when people are already anxious about what they’re taking.

I personally use RU and get zero side effects, but that doesn’t mean everyone will respond the same.

I see, I use ru58841 too and haven't noticed any side effects either, albeit I started it only a month ago

 

[ICL]

Hey guys, I’m 18 and recently noticed some hair thinning, especially around the Hairline/temple and sides area. My hairline has always been a bit high, so I’m not sure if it’s normal maturation or actual thinning. I also notice some hair fall while applying oil or shampooing. I'm using minoxidil 5% from one week and sometimes rosemary oil too (ts from 2 months ig), what else can i do? And also from a recent blood work i got to know that I'm low on vitamin B12
The levels are:
Vitamin B12- 258 pg/ml (took supplements for 2 months
Vitamin D- 34 ng/dl (i took supplements for 5 months, earlier it was 12 ng/dl)
Ferritin- 48.4 ng/ml
(My father side hairs are good but my mother side uncles went bald in their early 30s)

Just get scalp advancement and a hair transplant bro tf is that upper third... brutal

 

[AstroSky]

I see, I use ru58841 too and haven't noticed any side effects either, albeit I started it only a month ago

if you can throw in some redlight therapy to your scalp 3 x a week or 4 for like 10 mins a day. works very well for hair thickness. but gotta do it often just dont OVER do it.

 

[ZyzzReincarnate]

if you can throw in some redlight therapy to your scalp 3 x a week or 4 for like 10 mins a day. works very well for hair thickness. but gotta do it often just dont OVER do it.

holy shit this nigga is back XD