High dose vitamin C potentially anti anabolic?

[positiveloop]

Office of Dietary Supplements - Dietary Supplements for Exercise and Athletic Performance

Overview for health professionals of dietary supplements for exercise and athletic performance. Research safety, health effects, and use here.

ods.od.nih.gov

"randomly assigned 54 healthy Norwegian men and women aged 20–30 years, most of whom were recreational exercisers, to receive 1,000 mg vitamin C and 235 mg (about 520 IU) vitamin E as DL-alpha-tocopherol or a placebo daily for 11 weeks while engaging in an endurance training program consisting mostly of running. Compared with placebo, the supplements had no effect on maximal oxygen consumption (VO2max, a measure of aerobic fitness and endurance capacity) or running performance. However, they significantly lowered levels of biochemical markers related to mitochondrial creation and exercise-induced cell signaling, thereby diminishing the desirable training-induced adaptations within skeletal muscle [20]."

Thoughts?

 

[lyricism]

Not surprised, DL-alpha-tocopherol is synthetic Vit E, not natural

The natural Vit E, found in foods like nuts, seeds, and vegetable oils, are a mix of different compounds called tocopherols and tocotrienols

DL-alpha-tocopherol is only used in supplements because its more stable and has a longer life than natural Vit E

PS: your title is misleading because the trial assess Vit C and DL-alpha-tocopherol as Vit E, not only Vit C

 

[positiveloop]

Not surprised, DL-alpha-tocopherol is synthetic Vit E, not natural

The natural Vit E, found in foods like nuts, seeds, and vegetable oils, are a mix of different compounds called tocopherols and tocotrienols

DL-alpha-tocopherol is only used in supplements because its more stable and has a longer life than natural Vit E

PS: your title is misleading because the trial assess Vit C and DL-alpha-tocopherol as Vit E, not only Vit C

Thank you, ive noticed but i thiight the levels were negligble, turns out its like 16× the RDA
So you think the vitamin E is to blame? smh i dont understand why they didnt just give them vit C alone.
Thinking of megadosing it for cortisol managment and protecitng from oxidative stress