HOW ERDA DELAYS GROWTH PLATE CLOSURE+WIDENS IT + HOW ITS ONE OF THE HIGHEST ROI HEIGHT COMPOUNDS [HIGH IQ]

[claygo]

Hello, uh, I’ll be honest: I just joined this forum. I know a lot about pharma, so I figured I’d spoon feed y’all from now on, I guess...

Disclaimer: this shit is probably water for high iq people(i doubt there are any on this forum though lmao), but for the average pharma dude, it isn’t.

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So, you may have seen some erdafitinib edits on TikTok showing studies where erdafitinib delays growth plate closure and also widens them.
So the pharma retards think this is from inhibition of fgfr3, but it’s not.
You will only see this effect on erda and not other "better" fgfr inhibitors such as tyra. Why?
Well, this growth plate effect of erda comes from potent inhibition of fgfr1-2, which alters the FGFR1/2–MAPK/ERK signaling axis in hypertrophic chondrocytes, increasing the COL10A1 (type X collagen)-positive hypertrophic zone and disrupting the normal transition from proliferating → hypertrophic chondrocytes → endochondral ossification, thereby expanding/widening the growth plate
(holy spoon feed)

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Conclusion​

Erda is probably the highest ROI height compound in com because it’s cheap as fuck, has lots of studies, and yeah lmao.

Bye.

Note: If I get a lot of reps on this post, I’ll start posting high effort shit with good formatting and more information/studies included, etc.

(Trust me, I know stuff you guys have never heard of.)

 

[Niebvll]

Yeah bro whatever just completely leave out that FGFR3 inhibition influences the same pathways and even telomerase activity
Saar me high iq you retard gtfo dont ever make a shitty guide like this again

 

[claygo]

Yeah bro whatever just completely leave out that FGFR3 inhibition influences the same pathways and even telomerase activity
Saar me high iq you retard gtfo dont ever make a shitty guide like this again

no xD fgfr3 inhibition does not increase collagen x which is the factor for the gp effect

 

[claygo]

Yeah bro whatever just completely leave out that FGFR3 inhibition influences the same pathways and even telomerase activity
Saar me high iq you retard gtfo dont ever make a shitty guide like this again

i love how your bio says hgh is cope

 

[Niebvll]

no xD fgfr3 inhibition does not increase collagen x which is the factor for the gp effect

Not even my point
It affects the same pathways

collagen is only a marker of hypertrophy, it doesnt even influence cell behavior

Youre also completely unaware of the telomerase effects but whatever LOL

i love how your bio says hgh is cope

Its a title and ofc its cope LOL
You claim high iq and cant even figure out that GH is velocity only

 

[ZyzzReincarnate]

 

[Niebvll]

@Paul.jnxy W high iq larps?

 

[claygo]

Not even my point
It affects the same pathways

collagen is only a marker of hypertrophy, it doesnt even influence cell behavior

Youre also completely unaware of the telomerase effects but whatever LOL

Its a title and ofc its cope LOL
You claim high iq and cant even figure out that GH is velocity only

first take: im not even answering this bro
second take: gh isn't velocity only. yes on studies it might look like it ages gps however if you actually look at it long term people who take gh grow for LONGER periods of time. so it does the opp lol./

 

[claygo]

@Paul.jnxy W high iq larps?

so now we are mentioning others?

 

[Niebvll]

first take: im not even answering this bro

Because you have no answer.
Conceded your point nice.

second take: gh isn't velocity only. yes on studies it might look like it ages gps however if you actually look at it long term people who take gh grow for LONGER periods of time. so it does the opp lol.

How fucking retarded are you
They dont grow for longer periods lol? The opposite is the case. You grow faster but for a shorter amount of time, thus equaling out the fah. And this isnt even the reason why GH doesnt work.
All studies you have been looking at are ISS or GHD so not even possible to use these as base to support GH working for normal teens.

so now we are mentioning others?

Yeah because he's a friend and will share my laughter at your retardation

 

[claygo]

Because you have no answer.
Conceded your point nice.

How fucking retarded are you
They dont grow for longer periods lol? The opposite is the case. You grow faster but for a shorter amount of time, thus equaling out the fah. And this isnt even the reason why GH doesnt work.
All studies you have been looking at are ISS or GHD so not even possible to use these as base to support GH working for normal teens.

Yeah because he's a friend and will share my laughter at your retardation

whats wrong with looking at iss studies? also no they literally grow for longer periods of time. we have proof that gh doesnt have a limit and that we can use as much as we want. and if you look at the studies, the more gh they use the more they grow. rothenbuler used 0.07mg/kg and got i think like 8.5cm in 11 months?

 

[Niebvll]

whats wrong with looking at iss studies?

Are you seriously asking this?
Maybe take a fucking look at polygenetic exclusivity

also no they literally grow for longer periods of time. we have proof that gh doesnt have a limit and that we can use as much as we want. and if you look at the studies, the more gh they use the more they grow. rothenbuler used 0.07mg/kg and got i think like 8.5cm in 11 months?

Are you retarded
More gain in height does not equal more time of growth.

 

[claygo]

Are you seriously asking this?
Maybe take a fucking look at polygenetic exclusivity

Are you retarded
More gain in height does not equal more time of growth.

again, if you look at long term studies people who use gh actually grow for longer periods of time. a small bone age advancement calculated via hand xray is not always accurate

 

[Niebvll]

again, if you look at long term studies people who use gh actually grow for longer periods of time.
a small bone age advancement calculated via hand xray is not always accurate

Yeah whatever bro
0 evidence for what you claim
Consistent >50% maturation velocity increase is totally "xray estimation errors"
Retard