daudthe1_
Medical Man
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- Mar 27, 2026
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SOURCE: https://pmc.ncbi.nlm.nih.gov/articles/PMC8235140/
MECHANISM OF ACTION:
Strontium attaches to CaSR receptors, meaning it can interact with calcium negatively, resulting in neither of them attaching to the receptors at all.
Another thing is that it increases the expression of RUNX2 and ALP, directly enhancing periosteal bone formation IF your growth plates are NOT closed
While it induces osteoblast activity, it also REDUCES osteoclast activity, functioning as a dual mechanism.
DOSAGE:
1.8G OF STRONTIUM RANELATE EVERY OTHER DAY FLUCTUATING WITH CALCIUM INTAKE TO AVOID INHIBITION AS MUCH AS POSSIBLE
MECHANISM OF ACTION:
Strontium attaches to CaSR receptors, meaning it can interact with calcium negatively, resulting in neither of them attaching to the receptors at all.
Another thing is that it increases the expression of RUNX2 and ALP, directly enhancing periosteal bone formation IF your growth plates are NOT closed
While it induces osteoblast activity, it also REDUCES osteoclast activity, functioning as a dual mechanism.
DOSAGE:
1.8G OF STRONTIUM RANELATE EVERY OTHER DAY FLUCTUATING WITH CALCIUM INTAKE TO AVOID INHIBITION AS MUCH AS POSSIBLE
