I researched for 1h 30min about mt2 and autism

Linus1888

Linus1888

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Im analyzing this study: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210389&type=printable

Its the only study about melanotan 2 and autism, its extremly hard to tell what the conclusion is as the mice get the mt2 injected trough an ICV Device which allows it to basically go trough the brain and skip the BBB.


Short: We have to inject atleast 470mg a day SubQ or Intranasaly for 14 days to get the same results as the mice in the study if were lucky. The dosage could also be 4700mg or higher as we dont know how much of the Peptide goes trough the BBB and thus ofcourse into the brain.

https://doi.org/10.1016/S0196-9781(98)00018-7 this is a comparison to insulin and amylin which go trough there better than mt2 does and its extremly low.

I will make a follow up thread on this.

@Jatt @chadisbeingmade @Stacyslayerᛉ @Hernan @theübermenschboy
 
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Im analyzing this study: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210389&type=printable

Its the only study about melanotan 2 and autism, its extremly hard to tell what the conclusion is as the mice get the mt2 injected trough an ICV Device which allows it to basically go trough the brain and skip the BBB.


Short: We have to inject atleast 470mg a day SubQ or Intranasaly for 14 days to get the same results as the mice in the study if were lucky. The dosage could also be 4700mg or higher as we dont know how much of the Peptide goes trough the BBB and thus ofcourse into the brain.

https://doi.org/10.1016/S0196-9781(98)00018-7 this is a comparison to insulin and amylin which go trough there better than mt2 does and its extremly low.

I will make a follow up thread on this.

@Jatt @chadisbeingmade @Stacyslayerᛉ @Hernan @theübermenschboy
Wait are you saying mt2 causes or cures autism?

I’m already perma tanned I shouldn’t use it
 
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Wait are you saying mt2 causes or cures autism?

I’m already perma tanned I shouldn’t use it
Mt2 can lower the bad of effects of autism trough oxytocin.

In the study there was a group of mice with ASD (Autism spectrum disorder), the goal of the study was to use melanotan2 to amplify oxytocin in the mice as it controls several neurochemical systems: „
serotonin, glutamate, dopamine, and
GABA neurotransmitters in the hypothalamus, amygdala, and hippocampus“


This study shows mt2 as a god sent autism “curer”, but the means of injection are IMPOSSIBLE for us. The best way of injection would be into the spine and near the brain in a fluid filled chamber. That is actually the easiest of the “effective injections”.

Our best option would be Intranasaly imo as it skips some steps in the Blood-brain-barrier.

I’m tweaking so much, it’s so much info and I’m so tired.
These are so many massive jnfos
 
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Mt2 can lower the bad of effects of autism trough oxytocin.

In the study there was a group of mice with ASD (Autism spectrum disorder), the goal of the study was to use melanotan2 to amplify oxytocin in the mice as it controls several neurochemical systems: „
serotonin, glutamate, dopamine, and
GABA neurotransmitters in the hypothalamus, amygdala, and hippocampus“


This study shows mt2 as a god sent autism “curer”, but the means of injection are IMPOSSIBLE for us. The best way of injection would be into the spine and near the brain in a fluid filled chamber. That is actually the easiest of the “effective injections”.

Our best option would be Intranasaly imo as it skips some steps in the Blood-brain-barrier.

I’m tweaking so much, it’s so much info and I’m so tired.
These are so many massive jnfos
Bro my brother had autism should I inject him

Don Ramon Agree GIF by Grupo Chespirito
 
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Wait are you saying mt2 causes or cures autism?

I’m already perma tanned I shouldn’t use it
Us this winter to cure our autism:

Image
327483 1 De 4 Fig7 HTML
IMG 5358
 
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research injectable oxytocin
 
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Bro my brother had autism should I inject him

Don Ramon Agree GIF by Grupo Chespirito
One vial per day and he could theoretically actually see great results at the 14 day mark
 
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Mt2 can lower the bad of effects of autism trough oxytocin.

In the study there was a group of mice with ASD (Autism spectrum disorder), the goal of the study was to use melanotan2 to amplify oxytocin in the mice as it controls several neurochemical systems: „
serotonin, glutamate, dopamine, and
GABA neurotransmitters in the hypothalamus, amygdala, and hippocampus“


This study shows mt2 as a god sent autism “curer”, but the means of injection are IMPOSSIBLE for us. The best way of injection would be into the spine and near the brain in a fluid filled chamber. That is actually the easiest of the “effective injections”.

Our best option would be Intranasaly imo as it skips some steps in the Blood-brain-barrier.

I’m tweaking so much, it’s so much info and I’m so tired.
These are so many massive jnfos
Another case of animal data saying one thing

ZERO human studies btw 😭😭
 
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One vial per day and he could theoretically actually see great results at the 14 day mark
He’s non verbal

I wish to hear him speak one day in my life time if there is a autism cure in my life time I don’t think so but still


chavo del 8 GIF by Grupo Chespirito
 
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research injectable oxytocin
Not good, it barely gets into the parenchyma trough the BBB and gets wrecked in the blood stream.

We would need these effects for a very long continuous time. Could again go intranasaly but then it’s the same shit again, just like with Mt2
 
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Another case of animal data saying one thing

ZERO human studies btw 😭😭
I was in clavs livestream when he made the claim “MELANOTAN 2 is the best preventative measure for autism” CRAZY INSANE Claim as there’s only one study.


It’s a promising study, if there was just a way for us to get it trough the BBB and into the brain at home
 
I remember seeing this too but bro 470mgs to fix autism at the cost of becoming black :forcedsmile::forcedsmile:
It’s winter soon, if you smear yourself completely full with spf 100 that fully blocks UVA and UVB it won’t be bad I’m sure.

500mg is a high dosage but it’s nothing unheard of, very quick tan though if you’re not careful. Your right
 
It’s winter soon, if you smear yourself completely full with spf 100 that fully blocks UVA and UVB it won’t be bad I’m sure.

500mg is a high dosage but it’s nothing unheard of, very quick tan though if you’re not careful. Your right
I remember I turned darker the same day with like 250mcg despite not going outside at all I don’t think you realize how much 500mgs of MELANOTAN2 really is
 
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Not good, it barely gets into the parenchyma trough the BBB and gets wrecked in the blood stream.

We would need these effects for a very long continuous time. Could again go intranasaly but then it’s the same shit again, just like with Mt2
so its same as melanotan, but can be used at higher dosages without tanning side effects
 
I remember I turned darker the same day with like 250mcg despite not going outside at all I don’t think you realize how much 500mgs of MELANOTAN2 really is
I’ve only ever been on 175 I believe and wasn’t a really high responder at all. Afterall 500mcg is almost 3x my highest dosage.

Depends on the person, I could raw dawg is with moles and freckles prolly
 
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I’ve only ever been on 175 I believe and wasn’t a really high responder at all. Afterall 500mcg is almost 3x my highest dosage.

Depends on the person, I could raw dawg is with moles and freckles prolly
You could still imagine what 500mgs would be like
 
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so its same as melanotan, but can be used at higher dosages without tanning side effects
It’s actually horrible, looked into it a bit more;

S.c/i.v. Injection: 3-6 minutes half time in the plasma and “Systemically administered oxytocin reaches the CSF but with poor BBB penetrance, i.e., on the order of 0.001% CSF recovery of the delivered dose”

That’s insanely shit, absolutely not worth looking further into this when having autism in mind
 
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Mt2 can lower the bad of effects of autism trough oxytocin.

In the study there was a group of mice with ASD (Autism spectrum disorder), the goal of the study was to use melanotan2 to amplify oxytocin in the mice as it controls several neurochemical systems: „
serotonin, glutamate, dopamine, and
GABA neurotransmitters in the hypothalamus, amygdala, and hippocampus“


This study shows mt2 as a god sent autism “curer”, but the means of injection are IMPOSSIBLE for us. The best way of injection would be into the spine and near the brain in a fluid filled chamber. That is actually the easiest of the “effective injections”.

Our best option would be Intranasaly imo as it skips some steps in the Blood-brain-barrier.

I’m tweaking so much, it’s so much info and I’m so tired.
These are so many massive jnfos
dude why dont you just use oxytocin, you know you can do that right?
 
holy shit, that's some intense research for mt2 and autism dude. crazy to think they had to inject so much just to get results from the mice
 
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Good thread. :feelsokman:
 
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holy shit, that's some intense research for mt2 and autism dude. crazy to think they had to inject so much just to get results from the mice
Thanks for the credits lol, I will maybe make a more detailed thread about it.
Again the dosages I mentioned are very speculative but if you were able to do an ICV injection in a human that weighs 70kg you would only need 0,47–0,57 mg/day. The span is because the mouse weighs 25-30gramms
 

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