If i take aromatase inhibitors (AI) during puberty to slow down growth plate fuson will I have less bone density?

[TNTD1209]

title

 

[ACNECell7]

no you faggot just make sure you the right ones so when you hop off you dont get estrogen rebound

 

[Navity]

Right on the money.

 

[anondude]

U Probaly won’t get any taller than u would without one tbh

 

[TNTD1209]

U Probaly won’t get any taller than u would without one tbh

why dy think that?

 

[anondude]

why dy think that?

Well people without gh deficiency’s don’t grow much taller on gh so why would just a ai work

 

[Ahmed88]

You won't grow a single mm, ais don't work, even if they did you you would need to nuke levels to 0 to even consider delaying growth plates by a single second, since even the littlest of estrogen will still close your plates in a normal rate


And yes you will loose bone density, libido destroy your brain health, and even height



Mark as solution

 

[فاشل]

You won't grow a single mm, ais don't work,

Didn't @Zagro already debunk ur ass?

And yes you will loose bone density,

Cope.

Sci-Hub. Effects of Suppression of Estrogen Action by the P450 Aromatase Inhibitor Letrozole on Bone Mineral Density and Bone Turnover in Pubertal Boys / The Journal of Clinical Endocrinology & Metabolism, 2003

ibido destroy.

That's a good thing, I jerk off way too much.

brain health

Cope.

Sci-Hub. Cognitive effects of aromatase inhibitor therapy in peripubertal boys / European Journal of Endocrinology, 2010

and even height

This kinda true ngl, not many people know this, you prob gonna need something to inhibit local e2, not that AIs don't do that already, but they aren't enough. I think letrozole already inhibits intracellular aromatisation to a significant degree, but u probs gonna need to use something like a serd, but that comes with its own problems.

even if they did you you would need to nuke levels to 0 to even consider delaying growth plates by a single second, since even the littlest of estrogen will still close your plates in a normal rate

 

[Ahmed88]

idn't @

@Zagro already debunk ur ass?

No? Read my the whole argument first

Cope.

Sci-Hub. Effects of Suppression of Estrogen Action by the P450 Aromatase Inhibitor Letrozole on Bone Mineral Density and Bone Turnover in Pubertal Boys / The Journal of Clinical Endocrinology & Metabolism, 2003

Lit says delayed puberty

The efficacy and safety of rhGH treatment combined with letrozole/GnRHa in adolescent boys - PMC

In boys during puberty who were undergoing recombinant human growth hormone (rhGH) treatment, we compared the therapeutic efficacy on growth, and any adverse reactions, of co-therapy with either letrozole or gonadotropin-releasing hormone analog ...

pmc.ncbi.nlm.nih.gov

Cope.

Sci-Hub. Cognitive effects of aromatase inhibitor therapy in peripubertal boys / European Journal of Endocrinology, 2010

There is still a theoretical concern