D
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Nicotine can increase the rate of which testosterone gets converted into DHT, dihydrotestosterone which is the stuff that causes your hair to fall out if you're prone to male pattern baldness.
If you think you might have the male pattern baldness gene, stop smoking/vaping and hop on finasteride and minoxidil ASAP. There have been many successful people who managed to save their hairline by taking immediate action to prevent it