I'll be trying aromatase inhibitors for height maxxing.

C

chopped_guy

Iron
Joined
Jul 20, 2025
Posts
68
Reputation
31
Idc anymore if aromatase inhibitors are cope or not. To convince myself they're not I gathered a few studies on idiopathic short stature; they were closest to a normal healthy human being like myself.

Yackobovitch-Gavan et al. 2025 (Israel) - POSITIVE RESULTS​

"AI treatment extends the growth period, resulting in an AHt surpassing initial predictions. Our findings underscore the potential of AI treatment in midpubertal boys with a short PAHt due to advanced BA and in those treated with GH for ISS."
This was with anastrozole though.

Mauras N, Ross JL, Gagliardi P, Yu YM, Hossain J, Permuy J, Damaso L, Merinbaum D, Singh RJ, Gaete X, Mericq V. Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature. J Clin Endocrinol Metab. 2016 Dec;101(12):4984-4993. doi: 10.1210/jc.2016-2891. Epub 2016 Oct 6. PMID: 27710241; PMCID: PMC5155684.
"
Combination therapy with AI/GH increases height potential in pubertal boys with ISS more than GH and AI alone treated for 24–36 months with a strong safety profile."

"Height gain [mean (SE)] at 24 months was: AI, +14.0 (0.8) cm; GH, +17.1 (0.9) cm; AI/GH, +18.9 (0.8) cm (P < .0006, analysis of covariance). Height SDS was: AI, −1.73 (0.12); GH, −1.43 (0.14); AI/GH, −1.25 (0.12) (P < .0012). Those treated through 36 months grew more. Regardless of treatment duration, height SDS at near-final height [n = 71; age, 17.4 (0.2) years; bone age, 15.3 (0.1) years; height achieved, ∼97.6%] was: AI, −1.4 (0.1); GH, −1.4 (0.2); AI/GH, −1.0 (0.1) (P = .06). Absolute height change was: AI, +18.2 (1.6) cm; GH, +20.6 (1.5) cm; AI/GH, +22.5 (1.4) cm (P = .01) (expected height gain at −2.0 height SDS, +13.0 cm)."

Did not have a control group but appears to work.

There are two studies that show negative result, I'll pretend they don't exist.

ppl here preach exemestane even though it's the drug least studied, I didn't find a single RCT on it.

So I'm going to use letrozole, it's the strongest on paper.


The following are my current stats:
15yo
170cm (around 5'7")
49.5kg rn (i know this is bad)
grew 5cm in 8 months
5'8" Dad and 5' mom

Current PAH is 175cm (5'9")


I'm trying to gain 3-4 more inches in total height that would put me 5'10-5'11 Which is realistic.

My full stack what ill be doing:
2.5mg of letrozole ED, i know you ppl with say this will crash my E2 hard but this is the dose actually studied.
Mirtazapine 15mg ED; antidepressant most likely to cause significant weight gain, which is desired.
Melatonin 3mg ED; actually good sleep is kinda hard ngl.
60k IU of vitamin D every 15 days; why not? half the world is deficient anyway.
[Please don't ask where i get these from]

Anything i'm doing wrong?
 
  • JFL
Reactions: Zagro and Deleted member 157297
Idc anymore if aromatase inhibitors are cope or not. To convince myself they're not I gathered a few studies on idiopathic short stature; they were closest to a normal healthy human being like myself.

Yackobovitch-Gavan et al. 2025 (Israel) - POSITIVE RESULTS​

"AI treatment extends the growth period, resulting in an AHt surpassing initial predictions. Our findings underscore the potential of AI treatment in midpubertal boys with a short PAHt due to advanced BA and in those treated with GH for ISS."
This was with anastrozole though.

Mauras N, Ross JL, Gagliardi P, Yu YM, Hossain J, Permuy J, Damaso L, Merinbaum D, Singh RJ, Gaete X, Mericq V. Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature. J Clin Endocrinol Metab. 2016 Dec;101(12):4984-4993. doi: 10.1210/jc.2016-2891. Epub 2016 Oct 6. PMID: 27710241; PMCID: PMC5155684.

"Combination therapy with AI/GH increases height potential in pubertal boys with ISS more than GH and AI alone treated for 24–36 months with a strong safety profile."

"Height gain [mean (SE)] at 24 months was: AI, +14.0 (0.8) cm; GH, +17.1 (0.9) cm; AI/GH, +18.9 (0.8) cm (P < .0006, analysis of covariance). Height SDS was: AI, −1.73 (0.12); GH, −1.43 (0.14); AI/GH, −1.25 (0.12) (P < .0012). Those treated through 36 months grew more. Regardless of treatment duration, height SDS at near-final height [n = 71; age, 17.4 (0.2) years; bone age, 15.3 (0.1) years; height achieved, ∼97.6%] was: AI, −1.4 (0.1); GH, −1.4 (0.2); AI/GH, −1.0 (0.1) (P = .06). Absolute height change was: AI, +18.2 (1.6) cm; GH, +20.6 (1.5) cm; AI/GH, +22.5 (1.4) cm (P = .01) (expected height gain at −2.0 height SDS, +13.0 cm)."

Did not have a control group but appears to work.

There are two studies that show negative result, I'll pretend they don't exist.

ppl here preach exemestane even though it's the drug least studied, I didn't find a single RCT on it.

So I'm going to use letrozole, it's the strongest on paper.


The following are my current stats:​

15yo

170cm (around 5'7")

49.5kg rn (i know this is bad)

grew 5cm in 8 months

5'8" Dad and 5' mom

Current PAH is 175cm (5'9")

I'm trying to gain 3-4 more inches in total height that would put me 5'10-5'11 Which is realistic.

My full stack what ill be doing:​

2.5mg of letrozole ED, i know you ppl with say this will crash my E2 hard but this is the dose actually studied.

Mirtazapine 15mg ED; antidepressant most likely to cause significant weight gain, which is desired.

Melatonin 3mg ED; actually good sleep is kinda hard ngl.

60k IU of vitamin D every 15 days; why not? half the world is deficient anyway.

[Please don't ask where i get these from]

Anything i'm doing wrong?
go out in the sun for vitamin d instead of microdosing rat poison. this is stupid as fuck since estrogen is needed for bone growth
 
  • JFL
Reactions: chopped_guy
I wanna give some input here. Ive also read through alot of these studies and most of the time the kids e2 arent crashed, the e2 levels will be lower, but stay in the safe range. This is because its much harder to crash your e2 when your not taking exogenous testosterone. To put it in the simplest words, the brain detects that e2 is low, so it makes more test, so that the aromatase that cant be blocked can have more test to aromatize. Usually in the studies it will be like a 30%-60% increase in test and like a 40%ish drop in e2.

Since this thread is kinda old idek if your gonna respond to this, but did you ever take the letrozole? Im in a very similar position to you, 5'7 been 15 for about a month and a bit. I'm gonna take 1mg ed once i get my source figured out (The payment methods are all shit for every lab.) Maybe u wanna tell me your letro source :forcedsmile::forcedsmile::forcedsmile:
Do you think taking Aromasin would have the same or worse results
 
I think the reason most studies such a decrease in e2 levels, is because they are almost all using 2.5mg ed. Since i already have letrozole on the way, i'm gonna try taking it at a pretty low dose, like 0.5mg ed and then work up from there. I also want to take it for the really significant increases in DHT and test that are in a lot of studies. I think ill go up to 1mg ed and stay at that for 8 weeks and then come off of it and asses any changes (Height, weight, bf%, muscle mass, body hair, voice.) If i feel like shit after like 2 weeks, i'm just gonna come off of it and order anastrozole, the worst that happens is i have low e2 for like 4 weeks, as i just taper off of it i'm chilling.)

I feel like taking Letrozole towards the end of puberty like mid 16 or 17, to keep growth plates open for longer since its decreases e2 so much at those doses, would be a better use for it.
Yeah im bouta turn 16 in 2 months tryna max out my growth with 1.25 mg letrozole and 6 ius Hgh daily. Ive only grown an inch in the past year might be fried 🙏
 

Similar threads

xvdwbfa
Replies
5
Views
62
Adyta69
Adyta69
L
Replies
7
Views
78
nwed
nwed
O
Replies
6
Views
32
Michael854
Michael854
O
Replies
3
Views
51
overforme3
O

Users who are viewing this thread

Back
Top