injecting hgh before bed makes no sense if you don't megadose

[tempelcat4]

Natural gh secretion is in the deep sleep phase of your sleep, as more hours of deep sleep you have as more gh will be secreted.


For example: The same person A sleeps two nights, in both person A has the same stress levels, same sport, diet, etc. The only difference is that the person had in Night 1, 1 hour and 30 minutes of deep sleep, and in Night 2, 3 hours of deep sleep.

This means that person A secreted more gh in Night 2 because there was simply more time to secrete gh.
But there's a catch - gh secretion isn't linear, we can surely say person A secured more gh in Night 2, and that is true. But if we add another Night (Night 3), in which person A slept even 8 hours in deep sleep, this doesn't mean that gh is even higher. Because the body will stop production gh at some baseline.

For further understanding: Injecting 4 IU hgh before sleeping will hinder natural gh production.
This is referred to as a negative feedback loop. If you inject synthetic HGH (for example, 4 IU) before sleep, it could lead the body to think that there is enough GH present, and it may downregulate the endogenous production.

In comparison to natural GH production in one night, 4 IU can be considered a moderate to moderate-high dose. If injecting before sleep, a higher dose may be required to surpass or replace natural production.

Some professionals recommend injecting GH in the morning as this may coincide with the natural pattern of GH release during sleep. Especially if your not megadosing.

 

[tempelcat4]

Spoiler: bump

@Ascend ㅤ @Osie

 

[Deleted member 29747]

Natural gh secretion is in the deep sleep phase of your sleep, as more hours of deep sleep you have as more gh will be secreted.


For example: The same person A sleeps two nights, in both person A has the same stress levels, same sport, diet, etc. The only difference is that the person had in Night 1, 1 hour and 30 minutes of deep sleep, and in Night 2, 3 hours of deep sleep.

This means that person A secreted more gh in Night 2 because there was simply more time to secrete gh.
But there's a catch - gh secretion isn't linear, we can surely say person A secured more gh in Night 2, and that is true. But if we add another Night (Night 3), in which person A slept even 8 hours in deep sleep, this doesn't mean that gh is even higher. Because the body will stop production gh at some baseline.

For further understanding: Injecting 4 IU hgh before sleeping will hinder natural gh production.
This is referred to as a negative feedback loop. If you inject synthetic HGH (for example, 4 IU) before sleep, it could lead the body to think that there is enough GH present, and it may downregulate the endogenous production.

In comparison to natural GH production in one night, 4 IU can be considered a moderate to moderate-high dose. If injecting before sleep, a higher dose may be required to surpass or replace natural production.

Some professionals recommend injecting GH in the morning as this may coincide with the natural pattern of GH release during sleep. Especially if your not megadosing.

This is theory or do you have any medical literature saying that this true? and the reason why your gh won’t go higher is because of somastatin so just use a somastatin inhibitor, I think you also forget that while taking 2ius+ your natural growth hormone will stop producing so actually it would make sense to inject at night, since your natural gh wont be there.

 

[tempelcat4]

This is theory or do you have any medical literature saying that this true? and the reason why your gh won’t go higher is because of somastatin so just use a somastatin inhibitor, I think you also forget that while taking 2ius+ your natural growth hormone will stop producing so actually it would make sense to inject at night, since your natural gh wont be there.

does that mean that through somatostatin inhibitor there would be no baseline anymore?

 

[HGHmaxxed]

Negative feedback loops are long term in nature, your production declines evenly for the whole day if you are pinning 4 iu. It will not matter if you take before bedtime or after.

Every major pharmacy recommends taking before bedtime.

 

[Dystopian]

The body produces a lot less than the equivalent of 4iu everyday

 

[HGHmaxxed]

Suppression and recovery of GH secretion after GH injection in non-GH deficient short children - PubMed

After 6 months of a thrice weekly GH treatment regimen in non-GH deficient short children, endogenous GH secretion was reduced from 24 to 36 h after injection compared to placebo and returned to control levels by 48 to 60 h after injection.

pubmed.ncbi.nlm.nih.gov

To support my statement, GH is only suppressed after 24h. Its beneficial to pin it before bedtime only, because that's where your cortisol levels are at the lowest, and hence GH will have more efficacy.

 

[SADA]

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