Is Derma rolling cope?

[Deleted member 439]

https://www.oumere.com/blogs/news/h...breakdown-premature-aging-and-possibly-cancer
read this guys

However this study proves the opposite:

Overall 36 out of the total of 37 patients completed the treatment schedule and were evaluated for its efficacy. Out of these 36 patients, 34 achieved a reduction in the severity of their scarring by one or two grades. More than 80% of patients assessed their treatment as ‘excellent’ on a 10-point scale. No significant adverse effects were noted in any patient. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840919/

Be warned that this was done on scars not active acne
okay the more i search it seems legit (for hairgrowth also)
If anyone actually cares i can try to expand a bit and find some more indo

 

[fobos]

It is not cope. Every dermatologist offers this treatment, so it's obviously not bro science unlike her article.

 

[Extra Chromosome]

no

 

[You]

I have dermarolling scars due to it.

 

[Soulsmaxx]

https://www.oumere.com/blogs/news/h...breakdown-premature-aging-and-possibly-cancer
read this guys

However this study proves the opposite:

Overall 36 out of the total of 37 patients completed the treatment schedule and were evaluated for its efficacy. Out of these 36 patients, 34 achieved a reduction in the severity of their scarring by one or two grades. More than 80% of patients assessed their treatment as ‘excellent’ on a 10-point scale. No significant adverse effects were noted in any patient. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840919/

View attachment 49701Be warned that this was done on scars not active acne
okay the more i search it seems legit (for hairgrowth also)
If anyone actually cares i can try to expand a bit and find some more indo

I mean, I love mine. The lower grades have less risks, so .5mm once a week is cool for me.

 

[TBOLT]

not one word

 

[MadMong]

https://www.oumere.com/blogs/news/h...breakdown-premature-aging-and-possibly-cancer
read this guys

However this study proves the opposite:

Overall 36 out of the total of 37 patients completed the treatment schedule and were evaluated for its efficacy. Out of these 36 patients, 34 achieved a reduction in the severity of their scarring by one or two grades. More than 80% of patients assessed their treatment as ‘excellent’ on a 10-point scale. No significant adverse effects were noted in any patient. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840919/

This is the first I've ever heard of dermarolling causing short term benefits at the expense of reducing the lifespan of your skin's collagen production ability. Super interesting but also terrifying as it's one of the most effective ways to treat wrinkles, acne scarring and general signs of skin aging.

The study you linked does NOT prove the opposite. The author of the first link states that there are indeed short term benefits but every time you dermaroll and the skin is forced to create new collagen, you are decreasing the total amount of times the skin can create collagen. Meaning you could have fantastic skin until 45 and then suddenly your skin turns to complete shit and is unable to repair itself anymore.

Hoping that this isn't true. Reminds me of tanning.. look good short term but permanently ages your skin.


Found a rebuttal:

I am assuming you are referring to telomere shortening, causing aging due to the postulated Hayflick limit (theory).

It is fibroblasts and especially myofibroblasts that produce collagen. Since collagen production does not involve cell division and therefore telomere shortening (incidentally, not even sun damage causes telomere shortening) and collagen synthesis does not significantly wear out fibroblasts (which would eventually force them to divide, causing telomere shortening), we can assume that there is no risk of premature skin aging associated with microneedling.

Even if it were the case that collagen synthesis would cause telomere shortening, experts still believe that this will not result in premature aging:

Skin biologist Dr. Pickart investigated the Hayflick Limit (max. cell division limit due to telomere shortening) in his 1973 Ph.D. thesis and took the position that the Hayflick theory is at least partially incorrect. He argued that the theory of cells only being able to regenerate up to a certain generation or limit is unfounded. Dr. Pickart states that skin stem cells are plentiful in the skin, so that cells could continually be generated and remodeling can continue to occur. In the year 2000, it was discovered that the skin has a constant source of new stem cells that arise from vellus hair follicles. This work has been confirmed in many laboratories.

As for limits on cell replication, most researchers in the area of cell culture doubt the Hayflick Limit (postulated about 1968) actually exists. If various growth factors are added to cultured cells, they seem to grow forever (for about 200 generations at least) without becoming mutated or cancerous. Such experiments are stopped not because the cells die, but because such long term experiments are expensive. Skin transplants from rat to rat to rat have been healthy for more than twice the lifespan of any rat.

"Stem cells by definition, have not yet been fully differentiated, and therefore many of these cells may continue to regenerate new cells for the entire lifespan of the organism, without limit, thus constituting a notable exception to the Hayflick limit in humans and other organisms. While the manifestations of the constant regenerative effects of stem cells is most easily seen in tissues which must constantly produce replacements for existing cells, such as skin and blood cells, stem cells of one form or another are found in every tissue of the human body, even if only as dormant stem cells known as "spore-like cells"."

http://www.molecularstation.com/wiki/Hayflick_limit

Cancer cells possess an enzyme called telomerase which is able to restore telomere length.

We conclude that there is no reason to believe that collagen production leads to telomere shortening, and that it even is controversial that telomere shortening causes premature skin aging.

In fact:

http://en.wikipedia.org/wiki/Telomere



In vitro studies (von Zglinicki et al. 1995, 2000) have shown that telomeres are highly susceptible to oxidative stress. Telomere shortening due to free radicals explains the difference between the estimated loss per division because of the end-replication problem (ca. 20 bp) and actual telomere shortening rates (50-100 bp), and has a greater absolute impact on telomere length than shortening caused by the end-replication problem.



From that follows that skin ages mainly due to oxidative stress (and, even more so, sun exposure). Microneedling involves the pre- and post-application of fat-soluble (vit. A) and water-soluble (vit. C) vitamins, and because those powerful antioxidants they are applied to "open" skin, the powerful anti-oxidative effect of these vitamins brought deep into the skin counteract one of the most powerful causes of skin aging - oxidative stress.

So far, medium-term studies show significant improvement of microneedled skin that is sustained over the years that follow.

 

[Wannabe6ft2]

I've been doing it for more than a year. Fuck all results tbh

 

[Limerencel]

The study you linked is pubished in an Indian journal.
You should only rely on credible journals, preferably from the west.