L-Carnitine Effects on Androgen Receptor Sensitivity

[deltoidd]

If your androgen receptor density and sensitivity are low, you're missing out on gains as testosterone can't even bind to the androgen receptor inside of the muscle cell properly and trigger MPS. What is the most effective way to improve AR density and sensitivity? Any key things to avoid? I have seen plenty of videos on how injecting L-carnitine will improve your AR sensitivity, is there any literature that supports this claim or is it likely just a cope?

 

[radiaz]

Androgenic responses to resistance exercise: effects of feeding and L-carnitine

This is an article I've read before as I was also starting to wonder if I should supplement L-carnitine, so there is good evidence to say it could have a positive impact on your AR

 

[Histism]

If your androgen receptor density and sensitivity are low, you're missing out on gains as testosterone can't even bind to the androgen receptor inside of the muscle cell properly and trigger MPS. What is the most effective way to improve AR density and sensitivity? Any key things to avoid? I have seen plenty of videos on how injecting L-carnitine will improve your AR sensitivity, is there any literature that supports this claim or is it likely just a cope?

yes , it increases androgen receptor (AR) density and sensitivity

some articles which says it is real

The protective effect of L-carnitine on testosterone synthesis pathway, and spermatogenesis in monosodium glutamate-induced rats - PMC

Monosodium glutamate (MSG) is a food ingredient that is increasingly used commercially. MSG leads to oxidative stress, consequently suppressing steroid hormone production that causes defects in male reproductive system. This study aimed to evaluate ...

pmc.ncbi.nlm.nih.gov

Androgenic responses to resistance exercise: effects of feeding and L-carnitine - PubMed

In summary, these data demonstrated that: 1) feeding after RE increased AR content, which may result in increased testosterone uptake, and thus enhanced luteinizing hormone secretion via feedback mechanisms; and 2) LCLT supplementation upregulated AR content, which may promote recovery from RE.

pubmed.ncbi.nlm.nih.gov

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[deltoidd]

yes , it increases androgen receptor (AR) density and sensitivity

some articles which says it is real

The protective effect of L-carnitine on testosterone synthesis pathway, and spermatogenesis in monosodium glutamate-induced rats - PMC

Monosodium glutamate (MSG) is a food ingredient that is increasingly used commercially. MSG leads to oxidative stress, consequently suppressing steroid hormone production that causes defects in male reproductive system. This study aimed to evaluate ...

pmc.ncbi.nlm.nih.gov

Androgenic responses to resistance exercise: effects of feeding and L-carnitine - PubMed

In summary, these data demonstrated that: 1) feeding after RE increased AR content, which may result in increased testosterone uptake, and thus enhanced luteinizing hormone secretion via feedback mechanisms; and 2) LCLT supplementation upregulated AR content, which may promote recovery from RE.

pubmed.ncbi.nlm.nih.gov

---

If this reply helped you , please mark it as a solution through ✓ button.​

My only issue with it is that I feel it won't make much of difference, leading to money wasted for negligible gains. Do you think it is worth it to take?

 

[Histism]

My only issue with it is that I feel it won't make much of difference, leading to money wasted for negligible gains. Do you think it is worth it to take?

As long as you are growing , anything can help even if it gives small effects