“Life Extension Mix” Shortens Lifespan In Mice

[Youㅤ]

Oh, the irony. A supplement marketed to be anti-aging and extend lifespan… shortens lifespan.

https://www.lifeextension.com/vitamins-supplements/item02354/life-extension-mix-capsules

Control group: Black, Life Extension Mix group: White

The Life Extension Mix decreased median survival by 10.3% in a mouse model.

The Life Extension Stack:

Vitamin A, 467 IU
Vitamin C, 187 mg
Cholecalciferol, 75 IU;
Vitamin E (as d-α-tocopheryl succinate), 37.4 IU
Thiamine (vitamin B1) (as thiamine HCl), 11.7 mg
Riboflavin (vitamin B2), 237 μg
Niacin (vitamin B3) (as 53 % niacinamide, 38 % niacin, 9 % niacinamide ascorbate), 17.8 mg
Vitamin B6 (as pyridoxine HCI and pyridoxal 5′ phosphate coenzyme), 9.4 mg
Folic acid, 75 μg
Vitamin B12 (as 42 % cyanocobalamin, 42 % hydroxylcobalamin, 16 % ion exchange resin), 56 μg
Biotin, 280 μg
Pantothenic acid (as d-calcium pantothenate with pantethine), 56 mg
Calcium (as calcium carbonate, calcium ascorbate, d-calcium pantothenate, Calcium d-Glucarate), 20.4 mg
Iodine (as potassium iodide), 7.0 μg
Magnesium (as magnesium oxide, citrate, glycinate, taurinate, arginate, ascorbate), 37.4 mg
Zinc [as methionate (OptiZinc®3), zinc succinate], 33 mg
Selenium (as 50 % se-methylselenocysteine, 25 % l-selenomethionine (yeast free) (SelenoPure®4), and 25 % sodium selenate), 18.7 μg
Copper (as copper bisglycinate chelate), 93 μg
Manganese (as manganese gluconate), 93 μg
Chromium (as Chromium 454™5 bio-organic yeast extract matrix), 47 μg
Molybdenum (as sodium molybdate), 11.7 μg
Potassium (as potassium chloride), 3.5 mg
N-Acetyl- l-cysteine (NAC), 56.1 mg
Taurine, 200 mg; Inositol, 23.4 mg
Phosphatidylcholine (from soy), 14 mg
Choline (as choline bitartrate), 11.2 mg
Boron (as boron citrate/aspartate/glycinate complex), 280 μg
Ascorbyl palmitate (fat soluble vitamin C), 23.4 mg
para-Aminobenzoic acid (PABA), 18.7 mg
Trimethylglycine (TMG; as betaine anhydrous) (from sugar beets), 9.4 mg
α-Carotene 9.4 IU
Citrus bioflavonoid complex [50 % total bioflavonoids; Typical profile: (to equal 50 % total bioflavonoids) Flavanone (Hesperidin) 35 %, Flavonones (Naringin, Naringenin 7-B-Rutinoside and others) 14 %, Flavonols, Flavones and related phenolic compounds 1 %], 18.7 mg
Broccoli sprout concentrate (a proprietary blend of broccoli sprout concentrates and Calcium d-Glucarate providing sulforaphane, glucosinolates, D-3 T, and PEITC), 49 mg
Calcium d-Glucarate, 18.7 mg
Decaffeinated Green tea (Camellia sinensis) extract (leaf) [std. to 98 % polyphenols and 45 % Epigallocatechin gallate], 30.4 mg
Acerola juice powder extract 1:4 (Malpighia punicifolia fruit), 28.0 mg
Ginger root extract (Zingiber officinale root) [standardized for 5 % gingerols], 18.7 mg
HiActives 100 % fruit/berry complex (a proprietary blend of concentrated blackberry, blueberry, cranberry, elderberry, persimmon, plum, and cherry powders), 18.7 mg
VitaBlue®6 Wild Blueberry [(Vaccinium angustifolium) 130:1 extract (fruit) standardized to 14 % Total Phenolics, 4.9 % Total Anthocyanins, 660 ppm Pterostilbene], 14 mg
CocoaGold™ Cocoa bean extract (Theobroma cacao L.) [std. to 45 % polyphenols], 6.3 mg
Milk thistle extract (Silybum marianus) (seeds) [standardized for 85 % silymarin (85 mg)], 9.4 mg
Pomegranate (Punica granatum) extract (fruit) [standardized to 30 % Punicalagins], 7.9 mg
Bilberry extract (Vaccinium myrtillus) (berry) [standardized for 25 % anthocyanidins], 2.8 mg
Leucoselect®7 grapeseed extract (Vitis vinifera seeds) (std. for 95 % proanthocyanidins), 2.34 mg
BioVin®8 grape extract (Vitis vinifera, whole grapes) [std. for minimum 95 % proanthocyanidins, minimum 75 % total polyphenols as gallic acid monohydrate, minimum 200 ppm trans-resveratrol], 2.34 mg
Bromelain (from pineapple) (2,400 gelatin digestive units per gram), 1.4 mg
Lutein (purified concentrate from marigold flowers) (Tagetes erecta), 1.4 mg
Olive juice extract (fresh fruit) (std. to 50 % polyphenols, 6 % hydroxytyrosol), 1.17 mg
Sesame (Sesamum indicum) lignan extract, 930 μg
Luteolin [from perilla leaf extract (Perilla frutescens)], 748 μg
Lycopene (from natural tomato extract) (Lyc-O-Mato®9), 280 μg

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039264/

 

[Deleted member 23558]

choline, vitamin a, and the alpha tocopherol are responsible for the premature death. MAYBE Molybdenum and Chromium

 

[incel194012940]

its stupid to have a life extension mix with 1000000+ ingredients because its 100x easier to suicide through a pill than get a 10% increase in something, you're asking for it lmao

 

[Deleted member 23558]

Methionine, cysteine , omega 6 ( especially arachidonic acid) , linoleic acid , polyamine , ,COX 2, iron and tryptophan ( restriction of all these groups that is) is ALL YOU NEED

 

[IAMNOTANINCEL]

This is what a real life extension mix looks like

 

[Youㅤ]

Methionine, cysteine , omega 6 ( especially arachidonic acid) , linoleic acid , polyamine and tryptophan restriction is ALL YOU NEED

omega 3 should be restricted as well

I will be keeping my supplement stack to a minimum

 

[Deleted member 23558]

omega 3 should be restricted as well

I will be keeping my supplement stack to a minimum

Except DHA possibly. Doing research rn. Omega 6 is a much bigger causative in early mortality and omega 3 has its place when omega 6 consumption is higher.

 

[autistic_tendencies]

Humans are more advanced than mice
Stupid study

 

[autistic_tendencies]

omega 3 should be restricted as well

I will be keeping my supplement stack to a minimum

Good channel

 

[Deleted member 23558]

Good channel

Omega 3 especially EPA works by displacing arachidonic acid and decreasing prostagladin induced inflammation. Omega 3 is inevitable in the diet if youre actually eating anti aging foods. The ones to avoid are alpha linoleic acid. Omega 6 is much more dangerous. Although ideally you want almost 0 levels of both except DHA.

 

[autistic_tendencies]

Omega 3 especially EPA works by displacing arachidonic acid and decreasing prostagladin induced inflammation. Omega 3 is inevitable in the diet if youre actually eating anti aging foods. The ones to avoid are alpha linoleic acid. Omega 6 is much more dangerous. Although ideally you want almost 0 levels of both except DHA.

Is things like sardines salmon harmful ?

 

[Deleted member 23558]

Is things like sardines salmon harmful ?

Mercury , BPA. Probably depends on where they were grown.

 

[DR. NICKGA]

Oh, the irony. A supplement marketed to be anti-aging and extend lifespan… shortens lifespan.

https://www.lifeextension.com/vitamins-supplements/item02354/life-extension-mix-capsules

Control group: Black, Life Extension Mix group: White
View attachment 2611398

The Life Extension Mix decreased median survival by 10.3% in a mouse model.

The Life Extension Stack:

Vitamin A, 467 IU
Vitamin C, 187 mg
Cholecalciferol, 75 IU;
Vitamin E (as d-α-tocopheryl succinate), 37.4 IU
Thiamine (vitamin B1) (as thiamine HCl), 11.7 mg
Riboflavin (vitamin B2), 237 μg
Niacin (vitamin B3) (as 53 % niacinamide, 38 % niacin, 9 % niacinamide ascorbate), 17.8 mg
Vitamin B6 (as pyridoxine HCI and pyridoxal 5′ phosphate coenzyme), 9.4 mg
Folic acid, 75 μg
Vitamin B12 (as 42 % cyanocobalamin, 42 % hydroxylcobalamin, 16 % ion exchange resin), 56 μg
Biotin, 280 μg
Pantothenic acid (as d-calcium pantothenate with pantethine), 56 mg
Calcium (as calcium carbonate, calcium ascorbate, d-calcium pantothenate, Calcium d-Glucarate), 20.4 mg
Iodine (as potassium iodide), 7.0 μg
Magnesium (as magnesium oxide, citrate, glycinate, taurinate, arginate, ascorbate), 37.4 mg
Zinc [as methionate (OptiZinc®3), zinc succinate], 33 mg
Selenium (as 50 % se-methylselenocysteine, 25 % l-selenomethionine (yeast free) (SelenoPure®4), and 25 % sodium selenate), 18.7 μg
Copper (as copper bisglycinate chelate), 93 μg
Manganese (as manganese gluconate), 93 μg
Chromium (as Chromium 454™5 bio-organic yeast extract matrix), 47 μg
Molybdenum (as sodium molybdate), 11.7 μg
Potassium (as potassium chloride), 3.5 mg
N-Acetyl- l-cysteine (NAC), 56.1 mg
Taurine, 200 mg; Inositol, 23.4 mg
Phosphatidylcholine (from soy), 14 mg
Choline (as choline bitartrate), 11.2 mg
Boron (as boron citrate/aspartate/glycinate complex), 280 μg
Ascorbyl palmitate (fat soluble vitamin C), 23.4 mg
para-Aminobenzoic acid (PABA), 18.7 mg
Trimethylglycine (TMG; as betaine anhydrous) (from sugar beets), 9.4 mg
α-Carotene 9.4 IU
Citrus bioflavonoid complex [50 % total bioflavonoids; Typical profile: (to equal 50 % total bioflavonoids) Flavanone (Hesperidin) 35 %, Flavonones (Naringin, Naringenin 7-B-Rutinoside and others) 14 %, Flavonols, Flavones and related phenolic compounds 1 %], 18.7 mg
Broccoli sprout concentrate (a proprietary blend of broccoli sprout concentrates and Calcium d-Glucarate providing sulforaphane, glucosinolates, D-3 T, and PEITC), 49 mg
Calcium d-Glucarate, 18.7 mg
Decaffeinated Green tea (Camellia sinensis) extract (leaf) [std. to 98 % polyphenols and 45 % Epigallocatechin gallate], 30.4 mg
Acerola juice powder extract 1:4 (Malpighia punicifolia fruit), 28.0 mg
Ginger root extract (Zingiber officinale root) [standardized for 5 % gingerols], 18.7 mg
HiActives 100 % fruit/berry complex (a proprietary blend of concentrated blackberry, blueberry, cranberry, elderberry, persimmon, plum, and cherry powders), 18.7 mg
VitaBlue®6 Wild Blueberry [(Vaccinium angustifolium) 130:1 extract (fruit) standardized to 14 % Total Phenolics, 4.9 % Total Anthocyanins, 660 ppm Pterostilbene], 14 mg
CocoaGold™ Cocoa bean extract (Theobroma cacao L.) [std. to 45 % polyphenols], 6.3 mg
Milk thistle extract (Silybum marianus) (seeds) [standardized for 85 % silymarin (85 mg)], 9.4 mg
Pomegranate (Punica granatum) extract (fruit) [standardized to 30 % Punicalagins], 7.9 mg
Bilberry extract (Vaccinium myrtillus) (berry) [standardized for 25 % anthocyanidins], 2.8 mg
Leucoselect®7 grapeseed extract (Vitis vinifera seeds) (std. for 95 % proanthocyanidins), 2.34 mg
BioVin®8 grape extract (Vitis vinifera, whole grapes) [std. for minimum 95 % proanthocyanidins, minimum 75 % total polyphenols as gallic acid monohydrate, minimum 200 ppm trans-resveratrol], 2.34 mg
Bromelain (from pineapple) (2,400 gelatin digestive units per gram), 1.4 mg
Lutein (purified concentrate from marigold flowers) (Tagetes erecta), 1.4 mg
Olive juice extract (fresh fruit) (std. to 50 % polyphenols, 6 % hydroxytyrosol), 1.17 mg
Sesame (Sesamum indicum) lignan extract, 930 μg
Luteolin [from perilla leaf extract (Perilla frutescens)], 748 μg
Lycopene (from natural tomato extract) (Lyc-O-Mato®9), 280 μg

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039264/

Ah yes injecting 100 non absorbable suplements will surely extend you lifespand and not damage the liver and brain severly

 

[DR. NICKGA]

the thing to beat against the age clock is gene editing

editing all gene (that maybe got activated due to .. baby get exposed to 1000 metals (thats rlly a thing) -> certian gene get activated -> bad...) that cause the human body to age

also eating a good diet

 

[autistic_tendencies]

the thing to beat against the age clock is gene editing

editing all gene (that maybe got activated due to .. baby get exposed to 1000 metals (thats rlly a thing) -> certian gene get activated -> bad...) that cause the human body to age

also eating a good diet

Yeah some people are just programmed to age faster than others . The elite are working to alter the gene which triggers aging

 

[Deleted member 23558]

the gene which triggers aging

lol

 

[DR. NICKGA]

lol

If you don"t believe it then counter attack it with a argument and not "lol"

 

[Deleted member 23558]

If you don"t believe it then counter attack it with a argument not "lol"

Theres nothing to counter attack.

 

[Youㅤ]

Ah yes injecting 100 non absorbable suplements will surely extend you lifespand and not damage the liver and brain severly

It was taken with the chow