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Macropenis may result from complications from adrenal or pituitary disorders disorders[1],
or recurrent episodes of priapism which lead to excessive growth of the penile tissues[2]
Macropenis in children can derive from multiple causes, including an unusual rise in testosterone production, testicles with interstitial cell tumors, hyperplasia, an adrenal cortex with a tumor, precocious puberty and associated hypothalamic tumors or as a byproduct of other congenital anomalies. It can also occur due to a chromosomal disorder, such as inversion of chromosome 15 or deletion of chromosomal region 13q21q31.[3]
Some men have acquired the penis size above the median range through deliberate enhancement methods, through the usage of a specific device, a medicinal substance or through manual manipulation such as jelqing.[4]
or recurrent episodes of priapism which lead to excessive growth of the penile tissues[2]
Macropenis in children can derive from multiple causes, including an unusual rise in testosterone production, testicles with interstitial cell tumors, hyperplasia, an adrenal cortex with a tumor, precocious puberty and associated hypothalamic tumors or as a byproduct of other congenital anomalies. It can also occur due to a chromosomal disorder, such as inversion of chromosome 15 or deletion of chromosomal region 13q21q31.[3]
Some men have acquired the penis size above the median range through deliberate enhancement methods, through the usage of a specific device, a medicinal substance or through manual manipulation such as jelqing.[4]