Mixing Dutasteride Powder with castor oil for solubility (30mg/ml)

[axon]

So i found this study which shows the solubility of Dutasteride in different oils.
A lot of users, including myself use MCT Oil to dissolve the DUT and the solution often becomes oversaturated.

I usually found out: I need at least 1ml MCT for 2-3mg of DUT. I take 20mg so its a lot of oil to consume and this is not really backed up by studies.

Regarding that study we can use up to 30mg of DUT and just one 1ml of castor oil.
Tbh too good to be true so i may forgetting sth.

Not sure about the absorption part so MCT might still be better.
Or combine both oils? MCT for absorption and Castor oil for dissolving?

Preparation, Characterization and Stability Study of Dutasteride Loaded Nanoemulsion for Treatment of Benign Prostatic Hypertrophy - PMC

Benign prostatic hyperplasia (BPH)is the most common condition in aging men, associated with lower urinary tract symptoms. It is caused due to the augmented levels of the androgen dihydrotestosterone. Dutasteride, a 5α-Reductase inhibitor has been ...

www.ncbi.nlm.nih.gov

Tagging people that could be interested in that: @imontheloose @optimisticzoomer @chadisbeingmade

 

[optimisticzoomer]

I just use 1 mg/ml

 

[AlexRz]

I just use 1 mg/ml

Does that actually dissolve into a homogenous solution or is it a suspension solution that you need to shake before every use?

 

[optimisticzoomer]

Does that actually dissolve into a homogenous solution or is it a suspension solution that you need to shake before every use?

Seems pretty dissolved
I slightly shake it tho
I usually heat it to around 50°C for a bit when making it

 

[AlexRz]

Seems pretty dissolved
I slightly shake it tho
I usually heat it to around 50°C for a bit when making it

How do you heat it up and how do you know it’s at 50C? I got a magnetic stirrer but it doesn’t have a heating feature

 

[optimisticzoomer]

How do you heat it up and how do you know it’s at 50C? I got a magnetic stirrer but it doesn’t have a heating feature

Glass bottle in water on the stove
Thermometer

 

[AlexRz]

Glass bottle in water on the stove
Thermometer

How much have you managed to dissolve per ml with that method where it also stays stable and homogeneous at room temperature?

 

[optimisticzoomer]

How much have you managed to dissolve per ml with that method where it also stays stable and homogeneous at room temperature?

1 mg/ml

 

[stigmaboy]

u acting like 30mg/ml dutastride is gon do much anyway

heating it up tho kinda sus might degrade it tbh

 

[AlexRz]

1 mg/ml

Do you store it in the fridge after or do you just keep it room temp?

 

[stigmaboy]

@AlexRz lol @ 30mg/ml that's prolly just a suspension you gotta shake. 1mg/ml might actually dissolve but that's still high. you aiming for some mtn hairline shit?

 

[optimisticzoomer]

Do you store it in the fridge after or do you just keep it room temp?

Room temp

 

[AlexRz]

@AlexRz lol @ 30mg/ml that's prolly just a suspension you gotta shake. 1mg/ml might actually dissolve but that's still high. you aiming for some mtn hairline shit?

If it’s a suspension I think the bioavailability isn’t that good. I’m guessing 0.1-0.2mg/ml would dissolve. At least I hope so.

Taking 0.1mg daily has been proven throughout multiple studies to be as effective or even slightly more effective as 5mg fin faily so I don’t think it’s some just some mtn results tbh.