oral and topical minox?

[zachh]

want to grow goatee to make up for unideal chin projection and want to have mogger lashes and brows, rn using ordinary lash serum and topical minox on brows while dermastamping and wondering if i use topical and oral minox, will it give faster and/or better results?

 

[imontheloose]

No!

 

[zachh]

No!

y not

 

[Stranger to myself]

want to grow goatee to make up for unideal chin projection and want to have mogger lashes and brows, rn using ordinary lash serum and topical minox on brows while dermastamping and wondering if i use topical and oral minox, will it give faster and/or better results?

Both give the same results, its the matter if you have minoxidil sulphate on the area of application for topical. If you dont see results within a month, its time to switch to oral.

 

[imontheloose]

y not

I’ll explain. Both routes whether you consume it orally or apply it topically will end up targeting the same dermal papilla compartment. Once the local conc. is high enough to saturate the next step (the enzyme), any extra just diffuses away or might get just sent away in the blood. Once SULT1A1 is saturated, more substrate ≠ more sulfate!

If anything, all you’re doing is compounding irritation and side effects. 2.5mg oral will raise plasma levels to the point where SULT1A1 in most follicles is like maybe at the bare minimum, 95% saturated.

Going 5% topical + 2.5mg oral (bare in mind, 5% topical is roughly the same efficacy as 2.5mg oral it seems from the data) is just gonna barely nudge the plasma levels up but your systemic AUC is now doubled. You’ll just see even worse sides!

 

[zachh]

I’ll explain. Both routes whether you consume it orally or apply it topically will end up targeting the same dermal papilla compartment. Once the local conc. is high enough to saturate the next step (the enzyme), any extra just diffuses away or might get just sent away in the blood. Once SULT1A1 is saturated, more substrate ≠ more sulfate!

If anything, all you’re doing is compounding irritation and side effects. 2.5mg oral will raise plasma levels to the point where SULT1A1 in most follicles is like maybe at the bare minimum, 95% saturated.

Going 5% topical + 2.5mg oral (bare in mind, 5% topical is roughly the same efficacy as 2.5mg oral it seems from the data) is just gonna barely nudge the plasma levels up but your systemic AUC is now doubled. You’ll just see even worse sides!

gotcha ty