ANTI ANDROGENS
BY ASKINOV,
非物质的、无情的、超凡脱俗的伊玛·阿斯基诺夫
༺☣༺꧁SO LETS BEGIN꧂༻☣༻
WHAT IS ANTI ANDROGENS
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from their biological effects in the body.
They act by blocking the androgen receptor (AR) and/or inhibiting or suppressing androgen production.They can be thought of as the functional opposites of AR agonists, for instance androgens and anabolic steroids (AAS) like testosterone, DHT, and nandrolone and selective androgen receptor modulators (SARMs) like enobosarm. Antiandrogens are one of three types of sex hormone antagonists, the others being antiestrogens and antiprogestogens.
hope you get this
there are many types of anti androgen
1.Androgen receptor blocker.
2.5α - reductase inhibitors
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from their biological effects in the body.
They act by blocking the androgen receptor (AR) and/or inhibiting or suppressing androgen production.They can be thought of as the functional opposites of AR agonists, for instance androgens and anabolic steroids (AAS) like testosterone, DHT, and nandrolone and selective androgen receptor modulators (SARMs) like enobosarm. Antiandrogens are one of three types of sex hormone antagonists, the others being antiestrogens and antiprogestogens.
hope you get this
there are many types of anti androgen
1.Androgen receptor blocker.
2.5α - reductase inhibitors
ANDROGEN RECEPTOR BLOCKER
Mainly used for prostate cancer . Androgen receptor blockers (ARBs), also known as antiandrogens, are medications that prevent male hormones (androgens) from binding to androgen receptors. By blocking this interaction, these drugs stop androgens from fueling the growth of tissues and prostate cancer cells.
NCI Dictionary of Cancer Terms
NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.
these are not very very looksmaxx at looksmaxx at same time as they come with their side effects and is used in to treat cancer and hormonal acne these come in two types steroidal and nonsteroidal.
A steroidal antiandrogen (SAA) : is an antiandrogen with a steroidal chemical structure They are typically antagonists of the androgen receptor (AR) and act both by blocking the effects of androgens like testosterone and dihydrotestosterone (DHT) and by suppressing gonadal androgen production. SAAs lower concentrations of testosterone through simulation of the negative feedback inhibition of the hypothalamus SAAs are used in the treatment of androgen-dependent conditions in men and women, and are also used in veterinary medicine for the same purpose.They are the converse of nonsteroidal antiandrogens (NSAAs), which are antiandrogens that are not steroids and are structurally unrelated to testosterone.
USAGES
Prostate cancer in men
Benign prostatic hyperplasia in men
Benign prostatic hyperplasia (BPH) - Symptoms and causes
www.mayoclinic.org
other shit are done in women and fags ill link the wiki
Steroidal antiandrogen - Wikipedia
Cyproterone acetate (Androcur): A combined AR antagonist and progestogen/antigonadotropin. Also has weak glucocorticoid activity. Previously used widely in the treatment of prostate cancer, but since largely replaced by NSAAs. Also used for androgen-dependent indications in women and transgender women, precocious puberty in boys, and as a means of chemical castration for sexual deviation in men. Widely used in oral contraceptives as well (with ethinylestradiol under the brand names Diane and Diane-35). Not available in the United States. Uniquely among most SAAs, has a high risk of liver changes and hepatotoxicity. Also has a high incidence of psychiatric side effects such as depression, anxiety, and fatigue
this is also good at reducing sebum and hair growth
Spironolactone (Aldactone): An antimineralocorticoid (aldosterone antagonist) with additional/coincidental antiandrogen activity. Specifically acts as an AR antagonist, weak antigonadotropin, and weak steroidogenesis inhibitor. Used for androgen-dependent indications in women and transgender women, particularly in the United States where cyproterone acetate is unavailable. Studied in the treatment of benign prostatic hyperplasia but was found to be ineffective. Contraindicated in prostate cancer due to weak androgenic activity and stimulation of tumor growth. Most commonly used as a diuretic and antihypertensive for cardiovascular disease. Commonly associated with gynecomastia (breast development)
if you have hormonal acne you can go with spironolactone 500 to 200 mg daily
other drug ill link the wiki they have weak anti androgenic activity with weak glucocorticoid activity
Steroidal antiandrogen - Wikipedia
7 Common Antiandrogen Drugs: Uses, Names, and Testosterone Blockers - Liv Hospital
Explore antiandrogen drugs, their uses, names, and testosterone-blocking effects.
int.livhospital.com
Using potent systemic anti-androgens can drastically reduce testosterone levels, which can lead to feminizing side effects, erectile dysfunction, loss of libido, and reduced muscle mass.
A nonsteroidal antiandrogen (NSAA) is an antiandrogen with a nonsteroidal chemical structure. They are typically selective and full or silent antagonists of the androgen receptor (AR) and act by directly blocking the effects of androgens like testosterone and dihydrotestosterone (DHT). NSAAs are used in the treatment of androgen-dependent conditions in men and women They are the converse of steroidal antiandrogens (SAAs), which are antiandrogens that are steroids and are structurally related to testosterone
usages is same as steroidal
Flutamide (Eulexin): Marketed for the treatment of prostate cancer and also used in the treatment of acne, hirsutism, and hyperandrogenism in women. It has also been studied in the treatment of benign prostatic hyperplasia Now little-used due to high incidence of elevated liver enzymes and hepatotoxicity and the availability of safer agents.
RU-58841 (PSK-3841, HMR-3841): A first-generation NSAA related to nilutamide. It was under development as a topical medication for the treatment of acne and pattern hair loss but its development was discontinued during phase I clinical trials. its just block dht directly
here is the wiki if you know more
Nonsteroidal antiandrogen - Wikipedia
5α REDUCATSE INHIBTORS
Common one . 5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for transgender women.
These agents inhibit the enzyme 5α-reductase, which is involved in the metabolic transformations of a variety of endogenous steroids. 5-ARIs are most known for preventing conversion of testosterone, the major androgen sex hormone, to the more potent androgen dihydrotestosterone (DHT), in certain androgen-associated disorders
5-ARIs are clinically used in the treatment of conditions that are exacerbated by DHT
Mild-to-moderate benign prostatic hyperplasia and lower urinary tract symptoms
Pattern hair loss in both men and women
The usefulness of 5-ARIs for the potential treatment of acne is uncertain. 5-ARIs are sometimes used as antiandrogens in feminizing hormone therapy for transgender women to help reduce body hair growth and scalp hair loss.
yeah these are used for fags too lets get to some drugs and these drugs are mostly used to treat hair loss
5-ARIs are generally well tolerated in both men and women and produce few side effects. However, they have been found to have some risks in studies with men, including slightly increased risks of decreased libido, erectile dysfunction, ejaculatory dysfunction, infertility, breast tenderness, gynecomastia, depression, anxiety, self-harm, and dementia yeah all that shit
https://pubmed.ncbi.nlm.nih.gov/27784557/
the common drugs are finasteride and dutasteride are talked here a lot so these are in topical and oral form
sorry i wont be on org for some time so i will upload like this and this will be deleted from draft thats why im uploading so i can copy and more stuff to it when i come next time
@Sycophant @Menas @Navity @Sayori @buccalfatremoval
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