Peptide pouches cope

[gyno]

Seeing more people talk about "peptide pouches" like this jester ​

​

It won't work like it does with nicotine at all, here's why​

Spoiler: nicotine pouches

nicotine is the perfect molecule for buccal absorption​

it's a very small molecule that is lipophilic enough to cross membranes, meaning they're fat soluble and the membrane is mostly made out of fatty/oily barriers so it is basically needed to get absorbed, nicotine also stays stable in saliva and is highly potent.​

Nicotine passes through oral mucosa via passive diffusion​

most nicotine pouches are alkalanized(=higher pH) aswell, making the nicotine become more unionized= makes it cross lipid membranes easier​

So nicotine pouches are chemically optimized with a molecule that already wants to cross membranes and that's how they directly enter your bloodstream​

Spoiler: peptide pouches

Peptides basically aren't like nicotine at all
Peptides such as gluthatione or NAD are at least 2/3x bigger than nicotine molecules causing them to get blocked from the oral mucosa (without enhancers)

Most peptides are way above nicotine in size and complexity.

Now as i've said already, membranes are lipid(fat) based

peptides are hydrophilic or in other words "water-loving" and peps are not lipid-soluble

So peptides simply don't want to cross the fat barriers, nicotine does

Your saliva partially degrades peptides before absorption even becomes a question, this is because our saliva contains enzymes like proteases and peptidases

Alkalanization won't fix or help peptide absorption because of the reasons i just mentioned

To summarize, in simple words: nicotine slips through membranes into our bloodstream and peptides slam into our membranes and partially break before even getting to the membrane

Thanks for reading and don't buy this cope​

 

[Joeseminate]

Tf is this even going to do doesnt even say what is in them just 'peptides'

 

[xenovia]

This shits retarded. Can't even absorb or work in the mouth. Period.

 

[zenixx]

ngas be calling peptides anything

 

[gymcelld]

Snus is so shit

 

[sherry12]

​

Seeing more people talk about "peptide pouches" like this jester ​

​

​

It won't work like it does with nicotine at all, here's why​

​

Spoiler: nicotine pouches

nicotine is the perfect molecule for buccal absorption​

​

it's a very small molecule that is lipophilic enough to cross membranes, meaning they're fat soluble and the membrane is mostly made out of fatty/oily barriers so it is basically needed to get absorbed, nicotine also stays stable in saliva and is highly potent.​

​

Nicotine passes through oral mucosa via passive diffusion​

​

most nicotine pouches are alkalanized(=higher pH) aswell, making the nicotine become more unionized= makes it cross lipid membranes easier​

​

So nicotine pouches are chemically optimized with a molecule that already wants to cross membranes and that's how they directly enter your bloodstream​

​

Spoiler: peptide pouches

Peptides basically aren't like nicotine at all
Peptides such as gluthatione or NAD are at least 2/3x bigger than nicotine molecules causing them to get blocked from the oral mucosa (without enhancers)

Most peptides are way above nicotine in size and complexity.

Now as i've said already, membranes are lipid(fat) based

peptides are hydrophilic or in other words "water-loving" and peps are not lipid-soluble

So peptides simply don't want to cross the fat barriers, nicotine does

Your saliva partially degrades peptides before absorption even becomes a question, this is because our saliva contains enzymes like proteases and peptidases

Alkalanization won't fix or help peptide absorption because of the reasons i just mentioned

To summarize, in simple words: nicotine slips through membranes into our bloodstream and peptides slam into our membranes and partially break before even getting to the membrane

Thanks for reading and don't buy this cope​

greatest marking scheme of our generation these things are gonna do fucking numbers in the summer