Petition to ban all future height threads.

topology

topology

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People post literal GPT slop for reps and everyone eats it up.

For example: https://looksmax.org/threads/why-hgh-is-cope-and-will-not-work-for-you-hgh-users-gtfih.1887337/

He made many contradictions, stated incorrect facts in EVERY single one of his rebuttals, etc.

Not even a minor thing either, he stated that E2 should not be lowered because it messes with Collagen X, RUNX2, and SOX9 when that's the goal..? He made it seem like it was a bad thing. Clearly GPT slop. No one here knows anything. EVERYTHING is based upon the PTHrP loop, stop studying things such as the wnt/b-catenin pathways when you don't know the prerequisites.

Bud was talking about wnt/b-catenin causing the cells to go from proliferative -> pre hypertrophic regardless of estrogen levels when SOX9 doesn't allow for that to happen (SOX9 is higher with lower E2 if you couldn't tell). The argument has 0 merit since he claims lowering E2 is irrelevant for height. :forcedsmile::lul:

@Jason Voorhees @sergdying @Fridx @Scandicel @StyIix Sign the petition by repping this post.
 
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Shut the fuck up, fucking retarded nigger.
 
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i agree because im a manlet and I'm tired of seeing these threads mocking me every day.
 
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People post literal GPT slop for reps and everyone eats it up.

For example: https://looksmax.org/threads/why-hgh-is-cope-and-will-not-work-for-you-hgh-users-gtfih.1887337/

He made many contradictions, stated incorrect facts in EVERY single one of his rebuttals, etc.

Not even a minor thing either, he stated that E2 should not be lowered because it messes with Collagen X, RUNX2, and SOX9 when that's the goal..? He made it seem like it was a bad thing. Clearly GPT slop. No one here knows anything. EVERYTHING is based upon the PTHrP loop, stop studying things such as the wnt/b-catenin pathways when you don't know the prerequisites.

Bud was talking about wnt/b-catenin causing the cells to go from proliferative -> pre hypertrophic regardless of estrogen levels when SOX9 doesn't allow for that to happen (SOX9 is higher with lower E2 if you couldn't tell). The argument has 0 merit since he claims lowering E2 is irrelevant for height. :forcedsmile::lul:

@Jason Voorhees @sergdying @Fridx @Scandicel @StyIix Sign the petition by repping this post.
do u actually know topology or are u a larper
 
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do u actually know topology or are u a larper
You're aware this is irrelevant to the thread, right..? You can post such questions in PMs or my profile.

Also, not exactly sure what I could be "larping." I've made 0 statements about it and topology isn't something that I would "larp."
 
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i agree because im a manlet and I'm tired of seeing these threads mocking me every day.
Its honestly so fucking bad all these “heightmaxing” threads are just slop at the end of the day it will forever be genetics no amount of copeslop will make me a 6’5 terra chad, i expected i will be a turbo manlet and thats fine.:feelswhy:
 
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Its honestly so fucking bad all these “heightmaxing” threads are just slop at the end of the day it will forever be genetics no amount of copeslop will make me a 6’5 terra chad, i expected i will be a turbo manlet and thats fine.:feelswhy:
i love you bhai, dont you forget it :peepoLove:
 
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Its honestly so fucking bad all these “heightmaxing” threads are just slop at the end of the day it will forever be genetics no amount of copeslop will make me a 6’5 terra chad, i expected i will be a turbo manlet and thats fine.:feelswhy:
At what age did your growth plates close?
 
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i love you bhai, dont you forget it :peepoLove:
Thanks bhai:feelsgood:
IMG 3299
 
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At what age did your growth plates close?
They didn’t close yet im 5’4 at 16 i could potentially grow but honestly i gave up on the hopes of getting past 5’8
 
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Mirin knowledge.

You should make a height thread.

What works and what doesn't, debunk what doesn't with low iq vocab so the normies understand.
 
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Mirin knowledge.

You should make a height thread.

What works and what doesn't, debunk what doesn't with low iq vocab so the normies understand.
I made this which explains the PTHrP pathway & growth plate structure a lot.


What would work is upping the PTHrP levels which in turn ups SOX9 levels. This makes the cells move down the growth plate slower while also replicating more. Chondrocytes primarily end due to low PTHrP levels which is due to going further down in the growth plate as the PTHrP levels are a gradient

1774491950435


Imagine the pinker it is, the higher the PTHrP levels. The closer you get to the left side (the bone), the lower the levels are.

SOX9 is the main controller of cells going from the proliferative phase -> pre hypertrophic, the wnt/b-catenin pathways are lower in power. It directly stops other pathways from interfering if they try assuming the SOX9 levels are high enough.

So, what's the solution..? Waiting for AI chips to send signals to the pituitary gland to secrete GH will likely be done before all this.. It would be very difficult to get studies done on this anyways due to the risks.
 
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Have already seen this and repped.
What would work is upping the PTHrP levels which in turn ups SOX9 levels. This makes the cells move down the growth plate slower while also replicating more. Chondrocytes primarily end due to low PTHrP levels which is due to going further down in the growth plate as the PTHrP levels are a gradient

View attachment 4817456

Imagine the pinker it is, the higher the PTHrP levels. The closer you get to the left side (the bone), the lower the levels are.

SOX9 is the main controller of cells going from the proliferative phase -> pre hypertrophic, the wnt/b-catenin pathways are lower in power. It directly stops other pathways from interfering if they try assuming the SOX9 levels are high enough.

So, what's the solution..? Waiting for AI chips to send signals to the pituitary gland to secrete GH will likely be done before all this.. It would be very difficult to get studies done on this anyways due to the risks.
Correct.

Just unachievable:feelswhy:
 
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Just unachievable:feelswhy:
Locally injecting PTHrP can somewhat help if done properly as it could get into the growth plate but it's not reliable. There probably are some pathways that you could manipulate but it's going to get really twisted.
 
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Locally injecting PTHrP can somewhat help if done properly as it could get into the growth plate but it's not reliable.
Yeah that's what I was saying
 
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People post literal GPT slop for reps and everyone eats it up.

For example: https://looksmax.org/threads/why-hgh-is-cope-and-will-not-work-for-you-hgh-users-gtfih.1887337/

He made many contradictions, stated incorrect facts in EVERY single one of his rebuttals, etc.

Not even a minor thing either, he stated that E2 should not be lowered because it messes with Collagen X, RUNX2, and SOX9 when that's the goal..? He made it seem like it was a bad thing. Clearly GPT slop. No one here knows anything. EVERYTHING is based upon the PTHrP loop, stop studying things such as the wnt/b-catenin pathways when you don't know the prerequisites.

Bud was talking about wnt/b-catenin causing the cells to go from proliferative -> pre hypertrophic regardless of estrogen levels when SOX9 doesn't allow for that to happen (SOX9 is higher with lower E2 if you couldn't tell). The argument has 0 merit since he claims lowering E2 is irrelevant for height. :forcedsmile::lul:

@Jason Voorhees @sergdying @Fridx @Scandicel @StyIix Sign the petition by repping this post.
Bump
 
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