topology
igf 1 signaller/sugarmaxxer
- Joined
- May 24, 2025
- Posts
- 5,731
- Reputation
- 8,886
People post literal GPT slop for reps and everyone eats it up.
For example: https://looksmax.org/threads/why-hgh-is-cope-and-will-not-work-for-you-hgh-users-gtfih.1887337/
He made many contradictions, stated incorrect facts in EVERY single one of his rebuttals, etc.
Not even a minor thing either, he stated that E2 should not be lowered because it messes with Collagen X, RUNX2, and SOX9 when that's the goal..? He made it seem like it was a bad thing. Clearly GPT slop. No one here knows anything. EVERYTHING is based upon the PTHrP loop, stop studying things such as the wnt/b-catenin pathways when you don't know the prerequisites.
Bud was talking about wnt/b-catenin causing the cells to go from proliferative -> pre hypertrophic regardless of estrogen levels when SOX9 doesn't allow for that to happen (SOX9 is higher with lower E2 if you couldn't tell). The argument has 0 merit since he claims lowering E2 is irrelevant for height.

@Jason Voorhees @sergdying @Fridx @Scandicel @StyIix Sign the petition by repping this post.
For example: https://looksmax.org/threads/why-hgh-is-cope-and-will-not-work-for-you-hgh-users-gtfih.1887337/
He made many contradictions, stated incorrect facts in EVERY single one of his rebuttals, etc.
Not even a minor thing either, he stated that E2 should not be lowered because it messes with Collagen X, RUNX2, and SOX9 when that's the goal..? He made it seem like it was a bad thing. Clearly GPT slop. No one here knows anything. EVERYTHING is based upon the PTHrP loop, stop studying things such as the wnt/b-catenin pathways when you don't know the prerequisites.
Bud was talking about wnt/b-catenin causing the cells to go from proliferative -> pre hypertrophic regardless of estrogen levels when SOX9 doesn't allow for that to happen (SOX9 is higher with lower E2 if you couldn't tell). The argument has 0 merit since he claims lowering E2 is irrelevant for height.
@Jason Voorhees @sergdying @Fridx @Scandicel @StyIix Sign the petition by repping this post.

