Progression in genetic HEIGHT research (10-40% explained)

[Seth Walsh]

A large study by the GIANT consortium identified over 12,000 genetic variants influencing height, explaining 10-40% of height variation depending on ancestry. These discoveries, made by analyzing the DNA of 5.4 million people, highlight the impact of increasing sample sizes on understanding traits controlled by multiple genes.

Scientists Uncover Nearly All Genetic Variants Linked to Height

Largest genome-wide association study achieves ‘the impossible’

hms.harvard.edu

 

[Deleted member 23558]

in 40 years they will increase average height by one inch with genome sequencing, meanwhile if you take progesterone and thyroid before giving birth itll prolly make them 120 iq minimum and 6'0 minimum

 

[Seth Walsh]

The study uncovered rare variants affecting skeletal growth. New genes like SUSD5, GLT8D2, LOXL4, FIBIN, and SFRP4 were identified, and particularly, variations in STC2 significantly affected height. The STC2 protein acts as a brake on height, presenting a potential target for treating short stature

Tall Order

Study uncovers 83 new DNA changes that affect human height

hms.harvard.edu

 

[Seth Walsh]

in 40 years they will increase average height by one inch with genome sequencing, meanwhile if you take progesterone and thyroid before giving birth itll prolly make them 120 iq minimum and 6'0 minimum

Probs a lot more than a 1 inch increase on average lmao. 40 years from now is a long long time away. A lot will happen and I think geneticists will be focused on increasing mental capacity and eliminating diseases.

In real life being 6'0 compared to 6'4 isn't a huge deal like people online are tricked into believing. Sure being shorter is definitely a huge disadvantage but the whole 6'4+ thing is a meme.

What I worry about is what happens when "designer babies" become a thing we see more "Chad & Stacy faces". The world as a whole will have A LOT to answer for then.

 

[Deleted member 23558]

Probs a lot more than a 1 inch increase on average lmao. 40 years from now is a long long time away. A lot will happen and I think geneticists will be focused on increasing mental capacity and eliminating diseases.

In real life being 6'0 compared to 6'4 isn't a huge deal like people online are tricked into believing. Sure being shorter is definitely a huge disadvantage but the whole 6'4+ thing is a meme.

What I worry about is what happens when "designer babies" become a thing we see more "Chad & Stacy faces". The world as a whole will have A LOT to answer for then.

Genome sequencing has done nothing of worth since its inception.

 

[Seth Walsh]

Genome sequencing has done nothing of worth since its inception.

You might be thinking of gene editing with CRISPR and you're right; nothing has come out of that, I don't even think static gene editing could alter epigenetic expression to any great extent.

Inducing embryonic stem cells into a pluripotent state where they can differentiate into any three of the germ layers and from there, theoretically become any cell besides the cells of the placenta, can essentially aid in preventing diseases and more. iPSC has already been demonstrated in vitro using Yamanaka Factors and since the embryonic stage is prenatal.

 

[Deleted member 23558]

You might be thinking of gene editing with CRISPR and you're right; nothing has come out of that, I don't even think static gene editing could alter epigenetic expression to any great extent.

The Human Genome Project

The Human Genome Project was an inward voyage of discovery led by an international team of researchers looking to sequence and map all the genes of our species.

www.genome.gov

Altering a gene is risky and can lead to phenotypical mutations that can't be foreseen. Using genetics to create identical cells is impressive but it's not what the genome project was about.

 

[MTMM]

designer babies

only for ultra rich people and this will end the fucking human race,imagine youre a 5 ft 5 indian in 40 years and u see a fucking 7 ft guy that can throw you around like in cyberpunk