Quick heads-up for anyone thinking about self-administering pan-FGFR inhibitors

Zagro

Zagro

Roids over Foids
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The day you start taking this shit you will feel like shit overall, here are a few things ive noticed so far on erdafitinib at doses 5-10mg~:

Appetite: My appetite has been fucked comparable to my 5-8mg weekly retatrutide doses maybe even worse as eating large meals basically becomes a challenge itself but smaller meals split throughout the day is somewhat easier, but it still doesn't ensure you hit your needed caloric intake in a surplus as i have to force-feed myself for 2.000Kcals and above (this goes for whole foods, you could easily eat slop and make your experience a lot more miserable if you'd want to).

My tips and fix for this is just administering my growth hormone secretagogues (CJC no DAC, Ipamorelin and MK677) and recombinant growth hormone itself can help overall, androgens and thyroid hormones themselves also help the appetite noticeably.

Fatigue: The fatigue is the worst ive experienced. Would rather LDAR all day in my bed rather than going outside to take a walk, hang out with friends, hit the gym or just do simple tasks but still able to do all of this if i force myself to but with reduced performance in e.g. the gym.

Stimulants can help here but anything that will cause a crash will most likely rape any energy you have left, my personal fixes here are ECGC (not directly for erdafitinib), caffeine (maybe prolonged-release ones would benefit you more), concerta (long-acting stimulant not OTC) or like SSRIs even.

Dryness: My skin is peeling for some reason not anything significant but it's also not something ive noticed off things such as isotretinoin or topicals such as tretinoin and tazarotene. My mouth becomes the Sahara desert every few hours if i don't keep myself hydrated, but i just stuff myself up with water and zero sugar drinks so doesn't bother me.

Just hydrate yourself, moisturize your skin tbh.

Nails: Another weird thing is that since i have began with self-administering erdafitinib i have lost 1 toenail fully and have broken 3 other toenails, never ever had this much bleeding and broken nails from my usual long walks with 10-40k steps, came home and noticed i was leaving behind a trail of blood from my feet.

Everything else is alright so far. Heart feels a bit janky but this is because of my high dosed and prolonged blasts i did and it seems to improve so erda isn't the sole reason here. No retinopathy or anything with my eyes yet eventhough i don't use any eyedrops, but i seem to blink a lot more and my eyes get red/bloody quicker than normal.
 
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Is this the shit you said youd drop or is more coming
 
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Out of curiosity but why would you go for something that makes you so prone to shitty side effects while having minimal growth factor?
 
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Out of curiosity but why would you go for something that makes you so prone to shitty side effects while having minimal growth factor?
miniman growth factor????? are you high
 
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Is this the shit you said youd drop or is more coming
No this is just my experience

Out of curiosity but why would you go for something that makes you so prone to shitty side effects while having minimal growth factor?
I've used grams of gear i don't care about sides and it does not have "minimal" growth factor
 
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miniman growth factor????? are you high
Didn't research properly just asked out of knowledge from the first link I visited. Keep that attitude shoved up your rectum you silly gore watching larper
 
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No this is just my experience


I've used grams of gear i don't care about sides and it does not have "minimal" growth factor
How old are you?
 
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Fatigue: The fatigue is the worst ive experienced. Would rather LDAR all day in my bed rather than going outside to take a walk, hang out with friends, hit the gym or just do simple tasks but still able to do all of this if i force myself to but with reduced performance in e.g. the gym.
u sure this isnt the letro?

also why tf 10mg bro? dont u worry abt scoliosis on such a dose
 
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Reactions: Qeiea, 2s2f and Zagro
Do you have other update posts like this
Not really as i didn't experience much sides, only have one up with tren about the respiratory issues ive experienced on high dosages

How old are you?
16

u sure this isnt the letro?

also why tf 10mg bro? dont u worry abt scoliosis on such a dose
Can be honestly but i was on letrozole+tamoxifen before the erdafitinib and it got insane when both were introduced i cant even bother opening up my book to study for my last exams that could save my education or go outside but i can force myself
 
  • +1
Reactions: Qeiea, 2s2f and Niebvll
The day you start taking this shit you will feel like shit overall, here are a few things ive noticed so far on erdafitinib at doses 5-10mg~:

Appetite: My appetite has been fucked comparable to my 5-8mg weekly retatrutide doses maybe even worse as eating large meals basically becomes a challenge itself but smaller meals split throughout the day is somewhat easier, but it still doesn't ensure you hit your needed caloric intake in a surplus as i have to force-feed myself for 2.000Kcals and above (this goes for whole foods, you could easily eat slop and make your experience a lot more miserable if you'd want to).

My tips and fix for this is just administering my growth hormone secretagogues (CJC no DAC, Ipamorelin and MK677) and recombinant growth hormone itself can help overall, androgens and thyroid hormones themselves also help the appetite noticeably.

Fatigue: The fatigue is the worst ive experienced. Would rather LDAR all day in my bed rather than going outside to take a walk, hang out with friends, hit the gym or just do simple tasks but still able to do all of this if i force myself to but with reduced performance in e.g. the gym.

Stimulants can help here but anything that will cause a crash will most likely rape any energy you have left, my personal fixes here are ECGC (not directly for erdafitinib), caffeine (maybe prolonged-release ones would benefit you more), concerta (long-acting stimulant not OTC) or like SSRIs even.

Dryness: My skin is peeling for some reason not anything significant but it's also not something ive noticed off things such as isotretinoin or topicals such as tretinoin and tazarotene. My mouth becomes the Sahara desert every few hours if i don't keep myself hydrated, but i just stuff myself up with water and zero sugar drinks so doesn't bother me.

Just hydrate yourself, moisturize your skin tbh.

Nails: Another weird thing is that since i have began with self-administering erdafitinib i have lost 1 toenail fully and have broken 3 other toenails, never ever had this much bleeding and broken nails from my usual long walks with 10-40k steps, came home and noticed i was leaving behind a trail of blood from my feet.

Everything else is alright so far. Heart feels a bit janky but this is because of my high dosed and prolonged blasts i did and it seems to improve so erda isn't the sole reason here. No retinopathy or anything with my eyes yet eventhough i don't use any eyedrops, but i seem to blink a lot more and my eyes get red/bloody quicker than normal.
those things do shrink sebaceous glands so it makes sense on the skin side
 
  • +1
Reactions: Qeiea and 2s2f
The day you start taking this shit you will feel like shit overall, here are a few things ive noticed so far on erdafitinib at doses 5-10mg~:

Appetite: My appetite has been fucked comparable to my 5-8mg weekly retatrutide doses maybe even worse as eating large meals basically becomes a challenge itself but smaller meals split throughout the day is somewhat easier, but it still doesn't ensure you hit your needed caloric intake in a surplus as i have to force-feed myself for 2.000Kcals and above (this goes for whole foods, you could easily eat slop and make your experience a lot more miserable if you'd want to).

My tips and fix for this is just administering my growth hormone secretagogues (CJC no DAC, Ipamorelin and MK677) and recombinant growth hormone itself can help overall, androgens and thyroid hormones themselves also help the appetite noticeably.

Fatigue: The fatigue is the worst ive experienced. Would rather LDAR all day in my bed rather than going outside to take a walk, hang out with friends, hit the gym or just do simple tasks but still able to do all of this if i force myself to but with reduced performance in e.g. the gym.

Stimulants can help here but anything that will cause a crash will most likely rape any energy you have left, my personal fixes here are ECGC (not directly for erdafitinib), caffeine (maybe prolonged-release ones would benefit you more), concerta (long-acting stimulant not OTC) or like SSRIs even.

Dryness: My skin is peeling for some reason not anything significant but it's also not something ive noticed off things such as isotretinoin or topicals such as tretinoin and tazarotene. My mouth becomes the Sahara desert every few hours if i don't keep myself hydrated, but i just stuff myself up with water and zero sugar drinks so doesn't bother me.

Just hydrate yourself, moisturize your skin tbh.

Nails: Another weird thing is that since i have began with self-administering erdafitinib i have lost 1 toenail fully and have broken 3 other toenails, never ever had this much bleeding and broken nails from my usual long walks with 10-40k steps, came home and noticed i was leaving behind a trail of blood from my feet.

Everything else is alright so far. Heart feels a bit janky but this is because of my high dosed and prolonged blasts i did and it seems to improve so erda isn't the sole reason here. No retinopathy or anything with my eyes yet eventhough i don't use any eyedrops, but i seem to blink a lot more and my eyes get red/bloody quicker than normal.
Zagro why r we doing this to ourselves after blasting grams:feelsuhh:

Do u rlly think ur gp r still open after blasting grams of wtv the hell u were on:forcedsmile:
 
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Reactions: Qeiea and 2s2f
What's the best fgfr inhibitor to use in your opinion? I'm 18 and plates are in the process of fusing. Currently running HGH and anastrozole
 
Not really as i didn't experience much sides, only have one up with tren about the respiratory issues ive experienced on high dosages


16


Can be honestly but i was on letrozole+tamoxifen before the erdafitinib and it got insane when both were introduced i cant even bother opening up my book to study for my last exams that could save my education or go outside but i can force myself
The day you start taking this shit you will feel like shit overall, here are a few things ive noticed so far on erdafitinib at doses 5-10mg~:

Appetite: My appetite has been fucked comparable to my 5-8mg weekly retatrutide doses maybe even worse as eating large meals basically becomes a challenge itself but smaller meals split throughout the day is somewhat easier, but it still doesn't ensure you hit your needed caloric intake in a surplus as i have to force-feed myself for 2.000Kcals and above (this goes for whole foods, you could easily eat slop and make your experience a lot more miserable if you'd want to).

My tips and fix for this is just administering my growth hormone secretagogues (CJC no DAC, Ipamorelin and MK677) and recombinant growth hormone itself can help overall, androgens and thyroid hormones themselves also help the appetite noticeably.

Fatigue: The fatigue is the worst ive experienced. Would rather LDAR all day in my bed rather than going outside to take a walk, hang out with friends, hit the gym or just do simple tasks but still able to do all of this if i force myself to but with reduced performance in e.g. the gym.

Stimulants can help here but anything that will cause a crash will most likely rape any energy you have left, my personal fixes here are ECGC (not directly for erdafitinib), caffeine (maybe prolonged-release ones would benefit you more), concerta (long-acting stimulant not OTC) or like SSRIs even.

Dryness: My skin is peeling for some reason not anything significant but it's also not something ive noticed off things such as isotretinoin or topicals such as tretinoin and tazarotene. My mouth becomes the Sahara desert every few hours if i don't keep myself hydrated, but i just stuff myself up with water and zero sugar drinks so doesn't bother me.

Just hydrate yourself, moisturize your skin tbh.

Nails: Another weird thing is that since i have began with self-administering erdafitinib i have lost 1 toenail fully and have broken 3 other toenails, never ever had this much bleeding and broken nails from my usual long walks with 10-40k steps, came home and noticed i was leaving behind a trail of blood from my feet.

Everything else is alright so far. Heart feels a bit janky but this is because of my high dosed and prolonged blasts i did and it seems to improve so erda isn't the sole reason here. No retinopathy or anything with my eyes yet eventhough i don't use any eyedrops, but i seem to blink a lot more and my eyes get red/bloody quicker than normal.
Did you experience any sides on just 2.5 Letroze?
 
Can be honestly but i was on letrozole+tamoxifen before the erdafitinib and it got insane when both were introduced i cant even bother opening up my book to study for my last exams that could save my education or go outside but i can force myself
letro sides kick u later like 1-4 weeks. i took my first pill 4 days ago im chilling like absolutely 0 sides rn. as for motivation and focus maybe amphetamines? or some other stimulants. i do methylphenidate rn
 

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