Zagro
Roids over Foids
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- Aug 19, 2024
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Its literally linked to isotretinoin usage how do you not know that especially in higher doses such as you’re using atmi haven't ever heard of Accutane causing bone loss or plate closure unless used at insane doses, can you link me a study sar?
Any retinoic acid is capable of being detrimental to your bones (1).
I’m talking to the other cocky guy not you don’t worry, and not really it isn’t irreversible as long as you stop using such high doses and lower it you can avoid tipping into net bone resorption/lossno zagro blud, I'm not as sufficient in the osteoblast bone growth subject as you are sar, but I've been using 40mg isotretinoin for like 15 days, 60mg for 5 days and 80mg for 2 days and 100mg for one day, would that have caused severe damage already or nah?
Okay so it doesn’t specify that osteoclasts are cells that break down trabecular bone does itOsteoclasts are cells that break down bone.
Regarding the studies; please link it, I dont understand why isotretinoin would be resulting in 3cms of height loss. Maybe there is another pathway but Osteoclasts are surely not capable of compromising height that too at such an extent.
High doses, pre-/mid-puberty patients and long-term, but this isn’t even needed i would say that after like 20mg it will start becoming detrimental as time moves on
Check above for the study and this one (2) “(−0.67 cm; CI: −2.21 to 0.87)” although you could argue that they were below 15 it doesn’t mean that isotretinoin doesn’t have the properties to stunt growth