pomyioan
Bronze
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- Oct 20, 2025
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Semax and Selank are widely used by people in the biohacking community and by those who want to improve learning ability and productivity.
But there’s a huge catch:
With intranasal administration, only up to 1.69% of Semax and 1.04% of Selank actually reach the bloodstream.
And even less reaches the brain - only up to 0.13% of Semax and 0.16% of Selank.
Why does this happen?
Here’s the explanation:
- Enzymes in nasal mucus destroy about 96% of the compounds.
- Then brain microsomes break down another ~91% of what remains.
Conclusion for Semax and Selank:
To achieve the claimed effects, the required doses would need to be 100–500 times higher than the standard retail doses, or you would need to use a form that is protected from enzymatic degradation.
For example: N-acetyl-Semax.
But there’s a huge catch:
With intranasal administration, only up to 1.69% of Semax and 1.04% of Selank actually reach the bloodstream.
And even less reaches the brain - only up to 0.13% of Semax and 0.16% of Selank.
Why does this happen?
Here’s the explanation:
- Enzymes in nasal mucus destroy about 96% of the compounds.
- Then brain microsomes break down another ~91% of what remains.
Conclusion for Semax and Selank:
To achieve the claimed effects, the required doses would need to be 100–500 times higher than the standard retail doses, or you would need to use a form that is protected from enzymatic degradation.
For example: N-acetyl-Semax.
