SERM & AI discussion

[Sachlichkeit]

inject testosterone >>> T converts to E >> E give you man tits.

People run aromatase inhibitors to block the conversion of testosterone into estrogen during cycle to "normalize" their estrogen levels while keeping testosterone at steroid tier

AI's are also used to prevent growth plates from closing we already know this

estrogen is NECESSARY for normal function in like 10 separate significant ways we can't eradicate it from our body completely.

The selective estrogen receptor modulator RALOXIFENE is a drug intended for post menopausal women (I think) and has some unique properties.

First of all, in animal studies administration of raloxifene retarded longitudinal growth in animals with open growth plates. This is bad, but compared to estrogen which completely signals the ending of longitudinal growth its actually better than estrogen. I would go as far to say as its effects on plates are negligible when compared to estrogen

Low estrogen = cardiovascular risk
Low estrogen = Neurocognitive issues
Low estrogen = poor bone & joint health

Raloxifene acts on all these pathways. Is weaker than estrogen, but preferable if you plan on having very low E2 as a form of "synthetic estrogen," as it competes for estrogen receptors in breast tissue making it an anti-gynecomastia drug while simultaneously providing estrogenic benefits in the areas we want

 

[looksmaxxer29]

High iq

 

[Stacyslayerᛉ]

So you could nuke your E2 and take low dose tamoxifen, to mitigate low e2 side effects (myth jfl).

Mirin thread.

 

[Sachlichkeit]

So you could nuke your E2 and take low dose tamoxifen, to mitigate low e2 side effects (myth jfl).

Mirin thread.

Game is to reduce ERA

Sub 25e2 is preferable then raloxifene to lessen ERA effect in growth plates

Could theoretically nuke to near zero with letro, and supplement with the fetal HRT (weaker) estretrol, as well but theres lot of information to crunch for synthetic estrogen protocol.

Ya if u wanna be taller during puberty estrogen is important lever to spend time researching because it is the only trigger to close growth plates.

 

[Stacyslayerᛉ]

Game is to reduce ERA

Sub 25e2 is preferable then raloxifene to lessen ERA effect in growth plates

Could theoretically nuke to near zero with letro, and supplement with the fetal HRT (weaker) estretrol, as well but theres lot of information to crunch for synthetic estrogen protocol.

Ya if u wanna be taller during puberty estrogen is important lever to spend time researching because it is the only trigger to close growth plates.

Alright, mirin your posts, truly thankful there’s info like yours out here.

Quick question: you think low dose Tren (50mg) is ok, or should I use something like nandrolone? Also what protocol would you recommend for Epithalon?

Btw I’m 16, bone age ~14.5-14.75, and am nuking my e2 since before I turned 16.

Thanks

 

[BR32]

Made a whole thread on this today

Managing Estrogen on Cycle and Proper AI Use (High IQ ROIDERS GTFIH)

Basic Pharmacology Testosterone regardless of whether it is exogenous or endogenous gets converted into estradiol by the aromatase enzyme. This is natural and beneficial-moderate E2 levels are essential for Muscle growth Joint lubrication LIbido and erectile function Mood stability...

looksmax.org

 

[BR32]

Alright, mirin your posts, truly thankful there’s info like yours out here.

Quick question: you think low dose Tren (50mg) is ok, or should I use something like nandrolone? Also what protocol would you recommend for Epithalon?

Btw I’m 16, bone age ~14.5-14.75, and am nuking my e2 since before I turned 16.

Thanks

Tren doesn’t aromatize so you’re good on that front. I’d start out w 25-35mg for a couple weeks to see how it feels.

If you’re gonna run eptialon I would do 20 day cycles every 6 months or so at 1mg daily.

TBH tho there’s very minimal research on eptialon other than old Soviet studies.

 

[Sachlichkeit]

Tren doesn’t aromatize so you’re good on that front. I’d start out w 25-35mg for a couple weeks to see how it feels.

If you’re gonna run eptialon I would do 20 day cycles every 6 months or so at 1mg daily.

TBH tho there’s very minimal research on eptialon other than old Soviet studies.

pretty much I wouldn't even bother with epitalon if I was 16

Just GH AI + androgens and ancillaries, (Telmisartan, HCG, blablablah.) keep it simple, consistent, and educated (in minecraft)

@Stacyslayerᛉ​

 

[BR32]

Mirin post brah it makes me really happy to see people talking about proper E2 management.

Stg half of org probably has 0 estradiol

 

[BR32]

pretty much I wouldn't even bother with epitalon if I was 16

Just GH AI + androgens and ancillaries, (Telmisartan, HCG, blablablah.) keep it simple, consistent, and educated (in minecraft)

I agree only possible immediate benefit I could think of is normalizing circadian rhythm but there’s so much other stuff you can do instead for that.

 

[Stacyslayerᛉ]

pretty much I wouldn't even bother with epitalon if I was 16

Just GH AI + androgens and ancillaries, (Telmisartan, HCG, blablablah.) keep it simple, consistent, and educated (in minecraft)

@Stacyslayerᛉ​

Also would you say 25mg Meclizine is good, or should I do more or less?

Also is vorinostat from indiamart good, and will it be seized?

 

[Sachlichkeit]

Also would you say 25mg Meclizine is good, or should I do more or less?

Also is vorinostat from indiamart good, and will it be seized?

LGD-4033 during puberty worth it?

stats 16 still growing/ htn /5'10-11/ 55kg planning 2 consistent weeks of training pre cycle and currently on a clean bulk the plan is 8 weeks of LGD 5-7.5 mg a day overtime with 15mg MK677 (for max hunger/bulk and good sleep) with 4 weeks of enclo as PCT and maybe enclo during (week 2 to 4) to...

looksmax.org

read this thread starting with this post

AAS is a longterm commitment. Ancillaries vorinostat, meclizine, etc won't do anything compared to standard org HGH, AI, AAS.

Last time I checked theres no vorinostat in india as the generic isn't available, so any listings are a scam.
Go-to has been sourcing raw powder and self compounding it. though availability varies and is only something like 10%. if you do 25mg of self compounded SAHA (vstat) you can realistically expect 2.5mg to be absorbed minimum. the zolinza formulation has an availability of 43%.

whether something is seized depends on where you live

If I could go back, I would just sit and learn about X & Y for 2-3 months, compose a simple stack, start small & ramp up. Start crunching numbers as to how much its going to cost, how long you want to run, what to expect, where to source it all, etc.

16, you have time. in minecraft.

 

[Stacyslayerᛉ]

LGD-4033 during puberty worth it?

stats 16 still growing/ htn /5'10-11/ 55kg planning 2 consistent weeks of training pre cycle and currently on a clean bulk the plan is 8 weeks of LGD 5-7.5 mg a day overtime with 15mg MK677 (for max hunger/bulk and good sleep) with 4 weeks of enclo as PCT and maybe enclo during (week 2 to 4) to...

looksmax.org

read this thread starting with this post

AAS is a longterm commitment. Ancillaries vorinostat, meclizine, etc won't do anything compared to standard org HGH, AI, AAS.

Last time I checked theres no vorinostat in india as the generic isn't available, so any listings are a scam.
Go-to has been sourcing raw powder and self compounding it. though availability varies and is only something like 10%. if you do 25mg of self compounded SAHA (vstat) you can realistically expect 2.5mg to be absorbed minimum. the zolinza formulation has an availability of 43%.

whether something is seized depends on where you live

If I could go back, I would just sit and learn about X & Y for 2-3 months, compose a simple stack, start small & ramp up. Start crunching numbers as to how much its going to cost, how long you want to run, what to expect, where to source it all, etc.

16, you have time. in minecraft.

Tho boneage never comes back

And I’m mostly doing it for Height.

 

[Stacyslayerᛉ]

LGD-4033 during puberty worth it?

stats 16 still growing/ htn /5'10-11/ 55kg planning 2 consistent weeks of training pre cycle and currently on a clean bulk the plan is 8 weeks of LGD 5-7.5 mg a day overtime with 15mg MK677 (for max hunger/bulk and good sleep) with 4 weeks of enclo as PCT and maybe enclo during (week 2 to 4) to...

looksmax.org

read this thread starting with this post

AAS is a longterm commitment. Ancillaries vorinostat, meclizine, etc won't do anything compared to standard org HGH, AI, AAS.

Last time I checked theres no vorinostat in india as the generic isn't available, so any listings are a scam.
Go-to has been sourcing raw powder and self compounding it. though availability varies and is only something like 10%. if you do 25mg of self compounded SAHA (vstat) you can realistically expect 2.5mg to be absorbed minimum. the zolinza formulation has an availability of 43%.

whether something is seized depends on where you live

If I could go back, I would just sit and learn about X & Y for 2-3 months, compose a simple stack, start small & ramp up. Start crunching numbers as to how much its going to cost, how long you want to run, what to expect, where to source it all, etc.

16, you have time. in minecraft.

Alright, thanks so much for the response

Here my protocol and anything regarding my stack:

Heightmaxxing Update V - Keeping up the Progress + new Compound. (3 months in/93 Days)

HEIGHTMAXXING CYCLE UPDATE – 1.5 MONTHS LATER Hey guys, its been 1 and a half months again, so yeah heres an updated cycle update, what happened and my Height progress. Current Protocol: From the last update on i have had no breaks or interruptions, so heres my Daily protocol. 1mg...

looksmax.org

Just a quick question, do you know the source of the video I’ve always wondered where this vid came from.

 

[Sachlichkeit]

Alright, thanks so much for the response

Here my protocol and anything regarding my stack:

Heightmaxxing Update V - Keeping up the Progress + new Compound. (3 months in/93 Days)

HEIGHTMAXXING CYCLE UPDATE – 1.5 MONTHS LATER Hey guys, its been 1 and a half months again, so yeah heres an updated cycle update, what happened and my Height progress. Current Protocol: From the last update on i have had no breaks or interruptions, so heres my Daily protocol. 1mg...

looksmax.org

Just a quick question, do you know the source of the video I’ve always wondered where this vid came from.

brooo 5'6 I had no idea man im sorry 10iuhgh and an AI sounds good look into abaloparatide 1k test natural is great congrats

lol

 

[Stacyslayerᛉ]

brooo 5'6 I had no idea man im sorry 10iuhgh and an AI sounds good look into abaloparatide 1k test natural is great congrats

lol

Im almost 5ft8 now

And yeah why not Teri?

So here’s what imma add: 350 Test P, 50 Tren E, (Epithalon 10MG for 10Days), 25mg Meclizine, and yeah that’s it for now.
I’ll stay consistent with my stack and hope for the best.

Also you think nandrolone is superior to tren?

 

[Sachlichkeit]

brooo 5'6 I had no idea man im sorry 10iuhgh and an AI sounds good look into abaloparatide 1k test natural is great congrats

lol

Abaloparatide, SERM (Raloxifene) 10iu HGH & AI
I would say lean more on experimental minecraft estrogen replacement protocol but im not going to tell somebody to do something I haven't done myself in minecraft

 

[Sachlichkeit]

Im almost 5ft8 now

And yeah why not Teri?

So here’s what imma add: 350 Test P, 50 Tren E, (Epithalon 10MG for 10Days), 25mg Meclizine, and yeah that’s it for now.
I’ll stay consistent with my stack and hope for the best.

Also you think nandrolone is superior to tren?

scratch mec will probably nuke appetite, Abaloparatide is more selective and effective than teri, for osteoporosis nandrolone was the go-to before androgens were phased out for non androgenic solutions

Tren nand and test are 3 different androgens with 3 different purposes I might not even cycle if I just wanted to be taller

 

[Stacyslayerᛉ]

scratch mec will probably nuke appetite, Abaloparatide is more selective and effective than teri, for osteoporosis nandrolone was the go-to before androgens were phased out for non androgenic solutions

Tren nand and test are 3 different androgens with 3 different purposes I might not even cycle if I just wanted to be taller

So just run all 3 at once?

 

[lookingbad]

Abaloparatide, SERM (Raloxifene) 10iu HGH & AI
I would say lean more on experimental minecraft estrogen replacement protocol but im not going to tell somebody to do something I haven't done myself in minecraft

man what would u say is the best dosage for abaloparatide and raloxifene??

 

[Sachlichkeit]

man what would u say is the best dosage for abaloparatide and raloxifene??

standard pharma doses ive messed up my abaloparatide 2x this week and it makes u near debilitatingly nauseous

also ralox has cardiovascular risks because estrogen

 

[lookingbad]

standard pharma doses ive messed up my abaloparatide 2x this week and it makes u near debilitatingly nauseous

also ralox has cardiovascular risks because estrogen

right man..

what do u think about local estrogen conversion and growth plates closure??

 

[profilz]

standard pharma doses ive messed up my abaloparatide 2x this week and it makes u near debilitatingly nauseous

also ralox has cardiovascular risks because estrogen

What’s your dosing and source for abaloparatide?

 

[Genio]

inject testosterone >>> T converts to E >> E give you man tits.

People run aromatase inhibitors to block the conversion of testosterone into estrogen during cycle to "normalize" their estrogen levels while keeping testosterone at steroid tier

AI's are also used to prevent growth plates from closing we already know this

estrogen is NECESSARY for normal function in like 10 separate significant ways we can't eradicate it from our body completely.

The selective estrogen receptor modulator RALOXIFENE is a drug intended for post menopausal women (I think) and has some unique properties.

First of all, in animal studies administration of raloxifene retarded longitudinal growth in animals with open growth plates. This is bad, but compared to estrogen which completely signals the ending of longitudinal growth its actually better than estrogen. I would go as far to say as its effects on plates are negligible when compared to estrogen

Low estrogen = cardiovascular risk
Low estrogen = Neurocognitive issues
Low estrogen = poor bone & joint health

Raloxifene acts on all these pathways. Is weaker than estrogen, but preferable if you plan on having very low E2 as a form of "synthetic estrogen," as it competes for estrogen receptors in breast tissue making it an anti-gynecomastia drug while simultaneously providing estrogenic benefits in the areas we want

Good thread, I never recommend AI's unless the person is willing to get E2 Tests, especially since the margin from <5 and 15 ng/ml is really small to navigate in.