eyearea75
never enough
- Joined
- Apr 9, 2026
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For example Topical tretinoin mainly speeds up skin cell turnover and helps prevent clogged pores. Oral isotretinoin does so much more: it dramatically suppresses sebum production (often by ~80–90%), shrinks sebaceous gland activity, reduces C. acnes, and lowers inflammation, all at the same time. You just take the pill to your meal everyday and stick with it.
Source 1
This is also why isotretinoin can produce long-term remissions. Studies have shown that sebum production can remain significantly reduced for months and in some patients well over a year—after treatment ends, helping explain its lasting effects.
Source 2
If your dermatologist has already decided you’re a acne candidate, I don’t see the point of obsessing over “cope creams,” with cope methods and trying to perfect a routine. I’d rather focus on finding the perfect isotretinoin dose, than spend years chasing incremental improvements from topicals.
Stop overcomplicating acne treatment. Keep it simple and stick with it.
Source 1
This is also why isotretinoin can produce long-term remissions. Studies have shown that sebum production can remain significantly reduced for months and in some patients well over a year—after treatment ends, helping explain its lasting effects.
Source 2
If your dermatologist has already decided you’re a acne candidate, I don’t see the point of obsessing over “cope creams,” with cope methods and trying to perfect a routine. I’d rather focus on finding the perfect isotretinoin dose, than spend years chasing incremental improvements from topicals.
Stop overcomplicating acne treatment. Keep it simple and stick with it.