vinn98
The Apex Predator
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Strontium has a two-way effect on bone tissue. On the one hand, this element promotes formation of new bone tissue. By affecting osteoblasts, it increases their proliferation and differentiation. This is indicated by an increase in the expression of osteogenic genes such as Runx, ALP, BSP, and BGP [8].
New vertebral fractures occurred in fewer patients in the strontium ranelate group than in the placebo group, with a risk reduction of 49 percent in the first year of treatment and 41 percent during the three-year study period (relative risk, 0.59; 95 percent confidence interval, 0.48 to 0.73). Strontium ranelate increased bone mineral density at month 36 by 14.4 percent at the lumbar spine and 8.3 percent at the femoral neck (P<0.001 for both comparisons). There were no significant differences between the groups in the incidence of serious adverse events.
The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis - PubMed
Treatment of postmenopausal osteoporosis with strontium ranelate leads to early and sustained reductions in the risk of vertebral fractures.
pubmed.ncbi.nlm.nih.gov
You can buy it without prescription as strontium citrate.
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