ParanoidHungLatino
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"In the largest and longest US study to date, Mauras et al randomized 52 adolescent males with GH deficiency to treatment with GH and either daily co-treatment with anastrozole or placebo for up to 36 months (21). Of the original cohort, 50 subjects completed 12 months, 41 completed 24 months, and 28 completed 36 months. At study completion, linear growth was comparable between both groups; however, after 2 years, there was a significantly slower mean increase in BA advancement from baseline in the anastrozole vs the placebo group (+1.8 vs +2.78 years, p<0.0001) and after 3 years (+2.58 vs +4.18 years, p<0.0001). This difference resulted in a net increase in mean predicted adult height of 4.5 cm in the anastrozole group at 24 months and 6.8 cm at 36 months compared with a 1-cm gain at both time points in placebo group. During the course of the study, all boys on AIs had a normal tempo of pubertal virilization and, as expected, E2 and E1 concentrations increased less in the anastrozole vs the placebo group."
Note that if used at peak growth age(14-15), it will give you about 4.5-5cm height increase per 2 years. Notice people have proven on this forum already there is no estrogen rebound and that the theory estrogen affect the brain is stupid, since its only true in extreme cases. One will never "nuke" estrogen levels when taking AIs, they will only get 50-70% lower. So the idea that they affect brain is also completely false. Considering most research use 4-6 years of AIs, the kids get about 10-15cm height gain over predicted adult height. This would mean that any average couple who get access to AIs can make their male children tall, and any above average couple can make their child a future NBA prospect, all of this with no damage.
Average shortish couple would have a predict height for male sons of 170cm (5'7). Adding 15cm (6 inches), the kid would then be about 185(6'1). If the couple already have an average predicted height for their sons, say 177 (5'10), adding 15cm (6inches) will give their sons 192 (6'4) height, which is enough to try basketball pro leagues. So it is actually pretty simple to "produce" future tall kids. HGH is much less relevant than AIs unless the kid is HGH deficient.
Note that if used at peak growth age(14-15), it will give you about 4.5-5cm height increase per 2 years. Notice people have proven on this forum already there is no estrogen rebound and that the theory estrogen affect the brain is stupid, since its only true in extreme cases. One will never "nuke" estrogen levels when taking AIs, they will only get 50-70% lower. So the idea that they affect brain is also completely false. Considering most research use 4-6 years of AIs, the kids get about 10-15cm height gain over predicted adult height. This would mean that any average couple who get access to AIs can make their male children tall, and any above average couple can make their child a future NBA prospect, all of this with no damage.
Average shortish couple would have a predict height for male sons of 170cm (5'7). Adding 15cm (6 inches), the kid would then be about 185(6'1). If the couple already have an average predicted height for their sons, say 177 (5'10), adding 15cm (6inches) will give their sons 192 (6'4) height, which is enough to try basketball pro leagues. So it is actually pretty simple to "produce" future tall kids. HGH is much less relevant than AIs unless the kid is HGH deficient.
