Neko arc 14's
I have finished all my homework 😼[:v ou yia]
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More generally, the more amino acids there are in a peptide, the more susceptible they are to degradation. The fact that a peptide of 527 amino acids accompanied by peptides of almost all categories of chemical composition remained well stable in bacteriostatic water after 7 days is quite favorable to a peptide of 6 amino acids which hardly deserves further comment. In the above experiment the temperature was room temperature. Moreover, the benzyl alcohol in the water continued to keep bacteria at bay for at least 28 days.
-The general rule for peptides is that the less bacteriostatic water used for reconstitution, the greater the stability of the reconstituted solution. For example, in the case of the GHRP-2 5mg vial, 0.5ml of bacteriostatic water is sufficient and determines that the solution is stable for an extended period of time.
● In summary:
Use as little bacteriostatic water as possible in the reconstitution of the peptides.
- GHRPs are very stable.
- MOD GRF (1-29) is less stable.
If left reconstituted at room temperature for 7 days, they should remain effective. To minimize degradation of reconstituted peptides, it is recommended that reconstituted vials be refrigerated.
● Refrigeration greatly reduces degradation, 30 days for MOD GRF (1-29) and 60 days for GHRP should result in minimal degradation in bacteriostatic water.
● Reconstituting a vial removed from the freezer requires the vial to be at room temperature to warm its environment. Failure to do so may result in condensation/moisture in the vial, which may be detrimental to the peptide.
The peptide should dissolve on contact with the bacteriostatic water or it will soon have a clear appearance. Ideally, the reconstituted peptide should sit for a couple of hours to 24 hours to allow the benzyl alcohol to be in the bacteriostatic water and thus stop the multiplication of bacteria and make most of the bacteria present but inactive. The vial head should always be wiped with a cotton gauze with alcohol.
The insulin needle should be inserted into the top of the vial and some air expelled. The vial is turned upside down and the plunger backwards to draw several ui (the desired dose). The needle is removed from the vial and a fatty part (usually the middle section, well away from the umbilicus) is pinched.
The needle is inserted into the pinched and cleaned fat and the plunger is pushed all the way in. The needle is withdrawn. The vast majority of the time there is zero pain and no blood. If there is pain it goes away immediately. If there is blood just wipe gently with a tissue.
-The general rule for peptides is that the less bacteriostatic water used for reconstitution, the greater the stability of the reconstituted solution. For example, in the case of the GHRP-2 5mg vial, 0.5ml of bacteriostatic water is sufficient and determines that the solution is stable for an extended period of time.
● In summary:
Use as little bacteriostatic water as possible in the reconstitution of the peptides.
- GHRPs are very stable.
- MOD GRF (1-29) is less stable.
If left reconstituted at room temperature for 7 days, they should remain effective. To minimize degradation of reconstituted peptides, it is recommended that reconstituted vials be refrigerated.
● Refrigeration greatly reduces degradation, 30 days for MOD GRF (1-29) and 60 days for GHRP should result in minimal degradation in bacteriostatic water.
● Reconstituting a vial removed from the freezer requires the vial to be at room temperature to warm its environment. Failure to do so may result in condensation/moisture in the vial, which may be detrimental to the peptide.
The peptide should dissolve on contact with the bacteriostatic water or it will soon have a clear appearance. Ideally, the reconstituted peptide should sit for a couple of hours to 24 hours to allow the benzyl alcohol to be in the bacteriostatic water and thus stop the multiplication of bacteria and make most of the bacteria present but inactive. The vial head should always be wiped with a cotton gauze with alcohol.
The insulin needle should be inserted into the top of the vial and some air expelled. The vial is turned upside down and the plunger backwards to draw several ui (the desired dose). The needle is removed from the vial and a fatty part (usually the middle section, well away from the umbilicus) is pinched.
The needle is inserted into the pinched and cleaned fat and the plunger is pushed all the way in. The needle is withdrawn. The vast majority of the time there is zero pain and no blood. If there is pain it goes away immediately. If there is blood just wipe gently with a tissue.
