intro
hello guys and welcome to my first guide, my ultimate anti hair loss guide. I am not a medical expert but like to research a lot. There are also a lot of scam products on the market that I want to point out. My main knowledge comes from Derek (YouTube More plates more dates) and Kevin (Kevin mann on YouTube). 2 of the most knowledge guys on YouTube that I know. Check them out. The missing info in this guide and explanation is searched on hair loss forums. Also fighting hair loss can be one of the most complex problems. There are people using trenbelone and still having perfect NW 0 hair and people crashing their DHT and T to almost female levels and still having massive hair loss.
table of content
- The 4 stages of hair growth
- Why do we get bald?
- How to know if you are balding?
- What hormones play a role in the development of hair and hair loss?
- What products that work are available?
- What scam / cope products are available?
- Plan to fight balding
The 4 stages of hair growth
To explain why hair loss occurs the 4 different cycles need to be explained.
The growth phase, or anagen phase, lasts an average of 3-5 years — so a full-length hair averages 18 to 30 inches
At the end of the anagen phase, your hair enters the catagen phase. This short transitional phase lasts approximately 10 days.
The telogen phase is a resting period of around 3 months, when strands remain in their follicles but are not actively growing.
Finally, strands are released from their follicles and fall out. Now the whole process can begin again!
Each hair follicle is independent and goes through the growth cycle at different times — otherwise all your hair would fall out at once! Instead, you only shed a certain number of hairs a day – 80 to 100 hairs on a healthy head of hair.
View attachment 719467
Why do we get bald?
The vast majority of men go bald because of a hereditary condition called androgenic alopecia. Depending on the sensitivity of male hormones in the hair-follicles. The Anagen phase get shorter and shorter till a permanent state of anagen phase is present and the hair follicle is deactivated. The strongest hormone that shorten the Anagen phase is DHT (dihydrotestosteron) and testosterone. Some woman are so sensitive to DHT and testosterone that the small amount they products is sufficient to cause massive hair loss and some male are genetically blessed that they can use superficial amounts of testosterone and still got perfect hair. in a later chapter i will go in depth on the different hormones that play a role in hair loss and hair growth.
Stress is a serious health problem that may cause hair loss. stress may cause shortage of the hair cycle, increased inflammation in the body, that causes the immune system to attack the hair follicle and destroy it. stress can also cause excessive hair pulling resulting in damage of the hair follicle. Since this form of hair loss is not genetic and is more formed by lifestyle and environment this guide wont cover stress related hair loss. Hair loss from stress generally is not permanent when stress is lessened.
if you are not genetically predisposed to hair loss by hormone sensitivity or overly stressed but still got receding hairline or thinning hair, your diet could be the cause. Since you need a really bad diet to get vitamins deficient when perfectly healthy and you shouldn't have an excuse to eat healthy i will give a summary of vitamins and minerals needed for healthy hair.
The following vitamins and minerals play an role in hair loss:
- Vitamin D
- Iron
- Biotin (B3)
- omega 3-6 ratio (1-3 ratio or lower causes lower inflammation in the body)
The following minerals need more research:
- Zinc
- Riboflavin (B2)
- B12
- Folic acid (B9)
By using an app like chronometer your macros (fat, protein and carbs) and micros (vitamins and minerals) can be seen. Important note, because an app says you have eaten certain vitamins and minerals it doesn't mean everything is absorbed, so deficient can still occur. Blood work is needed to analyse if certain deficiencies are present.
While most over the counter drugs are unlikely to cause hair loss, many prescription drugs can have a negative effect on hair. The following common drugs can cause hair loss:
- Oral retinoids like Accutane
- Antidepressant
- Thyroid medications
- Steroids (especially the DHT derivatives and some SARMS, RAD 140 is one of the strongest SARMS causing hair loss)
Bad lifestyle can also play a role. Lack of sleep causes lack of essential hormones needed for healthy hair. Smoking ca also be bad and high amount of uv-light also. This guide wont cover the lifestyle part.
Excessive hairstyles that pull the hair tight such as pigtails, cornrows or a tight cap can cause hair loss. Try to be as gently at the hair as possible. This guide wont go more in depth about this topic.
Another cause of hair loss is toxicity of certain metals like, thallium, mercury, selenium and colchicine. These kind of toxicity mainly occur when the liver isn't working properly, genetic defect that causes accumulation of these toxins or eating an high amount of these toxins. And dermatologist got a device to read the toxicity of the hair. This hair wont go more in depth about this topic.
The last reason hair loss can occur is a fungal infection also known as ringworm. Circles with bumps is being formed where hair is lost. In the picture below ringworm is shown. Antibiotics are needed to fight this disease. This guide wont cover ringworm since its rare to occur.
View attachment 717816
How to know if you are balding?
The human head contains around 100.000 and is the thickest and most dense at around 16. After that point the hair is slowly losing density and receding depending at the hair lost each day. Every day around 50-100 hairs enter the anagen phase and regrows, so its important to lose less hair then that to at least keep your currently density. Also hair can stay in telegon phase. That way the hairline is slowly receding. Most normies are noticing they are losing density when they got around 30.000 hair left.
Hair loss for males is measured in the Norwood scale. In the picture below the Norwood scale is measured. Hair loss can start from the crown, temples or general thinning called defuse thinning. The most common is a receding hairline at younger age while thinning. Later the temples start thinning heavenly. Till NW 1.5 is perfect without (small) PSL lose. After that its a PSL lose. Especially younger people think they are receding when they are like 17, but its more likely they got a big forehead so its looks like its receding.
View attachment 719465
An easy way to check if you are balding is to buy a hair catcher. That is a type of bath tube drain that is used to catch hairs while showering. Since you lose the most hair when you are showering or bathing it's the most accurate way to know your hair loss. When you lose below 40/70 hairs you're hairline and density should be maintained or improved. Above is worsening of the hair. You can also use a hair catcher to notice your hair loss treatment is working or not.
An professional way of measuring hair loss is the use of a device called a trichometer. This device measures in an area its cross-sectional area. The device is not abla to measure a receding hairline, but can measure loss of density. The device can also have a microscope to analyze the hair further. The device can also have a microscope to examine the hair further.
Another way used by dermatologist to measure if you are thinning is the hair loss test. Around 40 hairs is pulled at different spots. When 6 or more hairs are lost you got active hair loss. Normal values for the hair pull test should be reduced to 2 hairs or fewer (97.2% of participants). https://www.sciencedirect.com/science/article/pii/S0190962216308921
When 6 or more hairs are lost you should hop on treatment asap or do nothing and fall into just shave it bro meme.
What hormones play a role in the development of hair and hair loss?
This paragraph is added to get more in depth about hormones. Hormones play in important role in hair loss and some treatment result in a change of the hormone profile which can cause massive problems in some unlucky individuals. Also the reason why certain medicines work is better explained.
DHT
The biggest cause of hair loss and the strongest androgenic hormone is DHT.
Dihydrotestosterone (DHT) is an androgen hormone, a type of male sex hormone found in both men and women. Androgen's are responsible for biological male characteristics like body hair, increased muscle mass, and a deeper voice. How exactly DHT hair loss occurs isn’t fully understood, but it’s thought that DHT attaches to androgen receptors on the hair follicles. Then DHT causes the hair follicles to shrink. As a result, the anagen, or growing, phase of the hair growth cycle decreases in length, while the telogen, or resting, phase of the hair cycle is extended.
5ar is directly happening near the hair follicle causing DHT buildup. DHT is +- 5 times as strong against hair loss as testosterone.
Some important genetic traits that causes DHT related hair loss.
View attachment 719605
Testosterone
Testosterone causes hair loss just as DHT. DHT is just 5 times as powerful so reducing DHT is usually enough to stop hair loss.
Cortisol
Cortisol is the stress hormone that causes the body to get in the fight or flight mode by directing as much as energy to vital organs. By extended time of the fight of flight mode the body gets depleted and inflammation occurs and causes degradation of cells. Since hair isn't vital its one of the first places where cell degradation occurs with hair loss as consequence. Hyaluronan and proteoglycans are important to skin elements that are responsible for hair growth. High cortisol levels reduce the synthesis and accelerate the degradation of these two skin elements almost by 40 percent, say researchers
Estradiol
Estradiol is a female hormone in the estrogen group. The hormone causes the hair to stay longer in the anagen phase. An increase in this hormone in males causes longer hair, but also less body hair. When Testosterone increases Estradiol also increases. Too much Estradiol may cause man-boobs.
Progesterone
Progesterone is another female hormone in the estrogen group. When Estradiol and progesterone ratio of off the hair gets thinner. Progesterone competes with 5ar to form DHT. when you get older less progesterone is formed so more DHT is formed resulting in hair loss.
Prolactin
Another female hormone. High amounts can cause hair loss. It's really rare for males and more common for females.
Thyroid hormones
Stem cells located at the bulges of the hair follicles are responsible for hair cycling and contribute to the regeneration of the new epidermis after wounding.
Thyroid hormone signaling is an important determinant of the mobilization of stem cells out of their niche in the hair bulge. Problems with thyroid hormones therefore
DHEA (Dehydro-epiandrosteron)
DHEA is a precursor to testosterone and estrogen. A low amount can cause hair loss, but it's really rare in males.
SHBG (sex-hormone-binding-glublin)
SHBG is a molecule that is comprised of carbohydrate and protein. The protein it contains is produced in the liver. Three different sex hormones bind to it. Estrogen, dihydrotestosterone (DHT), and testosterone are the hormones that bind with it. SHBG’s main job is to transport these hormones to various organs of the body. As SHBG has a stronger affinity for DHT and testosterone, it plays a crucial role in the maintenance of testosterone-estrogen balance in the female body. Problems with SHBG is rare.
PGD2
Another important Phospholipid is the PGD2. It works like a hormone on the body, but it isn't a hormone since it's a fat lipid and not a protein-like hormone. PGD2 is elevated in the scalp of bald people. PGD2 inhibits hair growth.
Some other functions PGD2 causes:
photo of PGD2 and other lipids. duo max size of images i it didnt fit in.
PG e2
A lipid that helps hair growth and maintains certain PGD2 and PGF2a levels. It also promotes the relaxation of tissue.
PGF2a
A lipid that helps hair growth and maintains certain PGD2 and PGF2a levels. It works against anti-inflammation.
What products that work is available?
In this paragraph, we explain what products are available, how good they work, and how they work.
Finasteride
finasteride is a FDA-approved drugs for hair loss that works by inhibiting 5ar and lowering DHT (strongest hormone that causes hair loss) levels in the body. Finasteride drops DHT by around 50-70%. By inhibiting DHT testosterone raises and so does estrogen. Topical finasteride drops DHT more in the hair and less in the body causing fewer side effects. ED problems occurred in less than 2% of the males so do not get afraid of the sides and do some bloodwork beforehand. Finasteride is one of the most used and most researched anti-hair loss medicine. Finasteride stops hair loss but doesn't cause a lot of regrowth (reversal on the Norwood scale). Using Finasteride should cause an initial shed for a few months.
Dutasteride
Dutasteride is an FDA-approved drugs (not for hair loss) that lowers DHT by around 90% it works just like Finasteride by blocking 5ar conversion of testosterone. it is only used for severe cases of MPB due to the strong drop of DHT. It's also possible to use a topical Dutesteride solution. This drops all the DHT almost completely in the scalp and should stop MPBin most cases. Dutasteride is way stronger than Finasteride and causes more side effects. Wherever the chance of ED in Finasteride is around 2% it's 5% for Dutasteride.
Azelaic acid
Azelaic acid is a weak 5ar inhibitor. Some studies claim it is stronger than Dutesteride, however anecdotal a lot of people claim it doesn't work. Its also never used as a stand-alone product, so it may work in conjunction with other products.
Alfratradiol
Alfratradiol is a weak estrogen, but weak enough that it doesn't cause feminization at higher doses. It works like Finasteride by stopping the 5ar conversion of testosterone to DHT.
It's weaker than Minoxidil as a regrowth but also is a light anti-androgen, so it increases density and stops hair loss moderately in a more natural way. Alfratradiol mixes well with RU58441. It can be used in conjunction with Finasteride or Dutasteride.
Minoxidil
Minoxidil is the strongest hair builder currently available on the market. It promotes the Anagen phase of the hair cell by opening the calcium channels in the hair follicle causing more nutrients to go to the hair. Possible by interfering with the PGD2/ PG 2e and PGF2a levels, but the exact way Minoxidil works is unknown. A lot of users notice the loss of collagen when using Minoxidil. It´s however not clinically proven so it may be fear-mongering.
Minoxidil may not work for everyone since Minoxidil needs to be converted to Minoxidil sulfate on the scalp and some people are unable to do. Around 40% got enough sulfotransferase enzymes to make Minoxidil work, unfortunately. Minoxidil may cause a shed for a certain amount of months, so I would advise using it for some months before saying if it works or not works. Minoxidil can be used orally or topical. Orally improves hair in the entire body, like the beard, eyebrows, and eyelashes. The side effects are worse tough. Any gains gotten with Minoxidil will be lost when stopped Minoxidil. Minoxidil doesn't stop the root of hair loss, the hormones, so it shouldn't use as the first product.
Nanoxidil
Nanoxidil is a hair grower just like Minoxidil. Its molecule almost identical to Minoxidil so the same result should be expected. There is no research proving that Minoxidil is better than Nanoxidil, so it's just a exspensive Minoxidil.
Stemoxydine
Stemoxydine is some kind of stemcells used to decrease the catagen phase so it's less long inactive. The exact reason for its work is unknown. It's way weaker than Minoxidil but barely got any side effects, but it isn't researched that much. When sopping Stemoxydine the hair isn't going to fall out, however, its advised to keep continuing Stemoxydine. Because it works differently then Minoxidil they can be stacked. Its weaker then 2% minoxidil and doesn't cause an initial shed. Stemoxydine is a great product to add to increase the hair density.
Stemoxydine is great stackable with RU58441.
CB-03-01 (Breezula)
Breezula is an anti androgen that works differently then Finasteride en Dutesteride. CB-03-01 competes with testosterone and DHT in the hair follicle, so less androgenic hormones gets absorbed. CB-03-01 recently got FDA approved. Breezula barely goes systemic and doesn't cause a (massive) shedding. The success stories depends per person of anti anti androgen's. There are people with really bad hair loss, who claim 0 effect and people with massive shedding who are on Dutesteride who got rid of the male pattern baldness (possible because testosterone was the last source of baldness). Not many side effects should occur. On high doses 2 times a day 7.5% Breezula should be better then Finasteride.
RU58441
RU58441 is the stronger and non approved version of CB-03-01. RU58441 should work really well against hair loss. The side effects of RU58441 is kinda tricky. Derek from more plates more dates says its probably not RU58441 and Kevin Mann thinks its because of low test. On hair loss forums there are multiple people claiming Heart palpitations, bad sleep etc. from RU58441. Allot use high doses tough. The exact long side effects are unknown. Research about Anti androgenic and certain medicines says they only occur when the testosterone is low, and RU58441 shouldn't go systemic enough to lose androgenic hormones in the body. Research shows that RU58441 works better against hair loss then Finasteride.
Fluridil
Fluridil is an anti androgen like Breezula and RU58441. It doesn't go systemic and study's shows that its a strong anti androgen, perhaps stronger then RU58441. It also shouldn't go systemic since its a hydrofoob and it shouldn't get absorbed in blood. Fluridil is expensive. Fluridil isn't use allot. of people on hair loss forums claims it isn't working, but they also claim RU58441 or Finasteride isn't working with them so take that with a grain of salt.
Spironolactone
Spironolactone is a strong anti androgen used against hair loss. Its mainly used by females because it blocks testosterone production and its used by males at high dosses who are transitioning to female. Males at hair loss forums are using it and some are claiming great success, but it comes with high risk so i don't recommend using it.
Ketoconazol
Ketoconazol is anti inflammatory product and a small DHT blocker used to threat hair loss, anti inflammatory and fungal problems. It helps a little bit against hair loss, but isn't as strong as AR5 inhibitors or anti androgen's, but its almost side effect free. Because of the weakness allot of people claim it isn't working. Derek from More plates more Dates advice to use it as first product, but Kevinn man says it doesn't work, even tough there are some anecdotal evidences he knows.
MK677 / HGH
Mk677 / HGH increases IGF-1 levels that increases cellular regeneration. The lower the IGF-1 levels the higher the resting phase of the hair follicles, the lower the hair density. IGF-1 is needed for hair growth and when this level is too low even without testosterone and DHT you will still be shedding. When IGF-1 levels are sufficient using MK677 or HGH doesn't change any hair density or stop MPB. Derek from More plates More dates says that MK677 works to increase hair density, but its more anecdotally.
Dermarolling / dermastamping
Whend dermarolling or dermastamping small needles are inserted into the scalp. Stand alone it doesn't increase density or help against male pattern baldness, but in conjunction with Minoxidil or topical Finesteride it increases the absorption or other products. 1.5 mm should be used 1 time a week.
Oral castor oil
Oral castor oil is a growth promoter weaker then Minoxidil or Stemoxydine, but way cheaper. It works by raising PGE2 levels in the body. Its a cheap almost side effect free way (except perhaps some stomach issues) to increase hair density. 1ml a day is enough, but up to 2ml is possible without diminishing returns. Its also combined with 5ar inhibitors and anti androgens for better results.
Lactobacillus ATCC PTA6475
An experiment medicine used to treat baldness. Clinical trials shows it works wonderful on mice. its hard to get it and Derek from more plates more dates didnt see any difference. It may work, but more research and testing is needed.
Latanoprost
Latanoprost is used to treat high pressure inside the eye due to glaucoma, but research on monkeys showed it was the best density builder available, better then Minoxidil and RU58441. It works as a PGE2 raiser. its however hella expensive and the people who experimented with it, barely claimed good results. Its also hard to find it on the black market so they may be scammed. It isn't a good stand alone treatment but can be used in conjunction with other products. It got the same working as Minoxidil, but it doesn't work good.
Travoprost
Works the same as Latanoprost.
Bimatoprost
Works the same as Latanoprost. Its slightly more researched and used. Its almost as good as Minoxidil, some people claim better results then Minoxidil. It raises PG e2 levels, losing scalp tension and increasing hair density.
Corticosteroids
Corticosteroids are topical steroids used for anti inflammatory and immune disorders. It shouldn't be used to treat MPB.
Cetirizine
Cetirizine inhibits PGD2 increasing hair density. It also reduces inflammations and irritations on the scalp. Its currently being researched in Germany. It should cause allot of density increase like Minoxidil. Not more is known and its only being tested at this moment.
Adenosine
This medicine is used for people with bad cardiovascular disease and got many side effects. A side effect is increasing hair density. It increases the dermal papal cell in the hair follicle creating healthier and more hair. Its very expensive and its weaker then Minoxidil.
Redensyl
Topical Redensyl is a density builder and helps to increase the dermal papilla cells health of the hair (bottom of the hair root) and works good against inflammation. So the hair survival rate increases 12-24% research shows. Research at cellular level shows its way better as hair density builder then Minoxidil. It isn't researched enough to conclude how good it works. People on hair loss forums noticed that Redensyl increased the hair density, but not as good as Minoxidil. It doesn't contain any side effects so i guess its a good hair product stackable with other products. I don't see enough info to confirm is this product isn't snake oil. Also this products can be sold commercially so the dosage and ingredients may differ per product.
Retinoids
Retinoids helps absorption of topical solutions like Finasteride or Minoxidil by exfoliating the upper scalp layer. Retinoids can be put into topical solutions easily by dropping a little bit in the solution.
Topical PGE2
Very expensive and impractical way to increase hair density, that barely works. In the future there may be a better, cheaper and more absorpele version.
What scam / cope products are available?
Head message
Improving blood flow causes helps against hair loss bullshit. Otherwise medicine that improves blood flow like heart medicine should work better. Bald people got just as much blood flowing through their scalp as non bald people. Otherwise the scalp of bald people would bleed less then non bald people, that isn't the case.
Red light cap
The studies are too low quality to prove red light works against hair loss and no visual evidence. Also not enough anecdotal evidence. Seems like snake oil to me.
pubmed.ncbi.nlm.nih.gov
Caffeine
The studies are industry funded. The head author is the same guy who is in the Alcapin comercials.
The only comparison didnt had an control group and didnt use a trichometer. Also concluded that it almost as strong as Minoxidil even anecdotally its proven otherwise.
It was industry funded and not reviewed by the industry.
www.ncbi.nlm.nih.gov
PRP
Blood is taken en in a centrifuge split. Some growth stimulants is added.
The blood is injected in the scalp again.
Only 1 study and the follow up study concluded the research didn't show any evidence like photos Not proven en not enough anecdotal evidence suggesting it works, especially at that price comparing to like Finasteride and Minoxidil.
www.painscience.com
Saw palmetto
There are some clinically studies proving the work of Saw palmetto. However the follow up study proves the study wasn't traceable enough and an comparison study noticed at was as effective as the placebo for prostate problems. DHT causes prostate problems so less problems should be noticed by using saw palmetto.
https://jamanetwork.com/journals/jama/fullarticle/1104439
Nutrafol
Overhyped scam product.
Peppermind oil
May work, but very minimal. Can cause irritation.
www.ncbi.nlm.nih.gov
Plan to fight hair loss
In this paragraph, i am going to discuss different forms of hair loss treatment plans. It's written in different levels of hardcoreness.
level 1 (not a lot of side effects extra note: all the options can be combined in 1 since they are stand alone)
Option A:
1-2ml castor oil daily
Pros: cheap while building density
Con: stomach issues may occur. Not the best density builder. Won't stop the cause of hair loss. Is tasting terrible.
Option B:
Ketoconazol shampoo 10 min once every other day
Pros: side effect free, helps against inflammation and dandruff
Con: depending on the quality the hair may feel to dry (regenpure is high quality, i use like 1 bottle for a few months), may not work well and be cope ;/. Doesn't stop the cause of balding. Takes 10 min every other day to use.
Option C:
Stemoxydine once a day (Stemoxydine Neogenic Garnier Fructis is cheap, but haven't tested it myself if its good)
Pros: side effect free and almost as strong as Minoxidil 2% in good trials
Con: Don't stop balding cause no DHT/ test blocker
Option D:
Redensyl (i don't know the dose and price, couldn't find a lot of info about it)
Pros: side effect free, could be decent density builder
Con: Not allot of info founded about it cause its kinda unknown (at-least for me)
Level 2 side effects may occur, but it should be enough for most people to stop hair loss.
Option A: Finasteride 0.5-1 mg daily (topical or oral, topical is expensive or takes more time to make, but slightly better)
Pros: stops the cause of hair loss, should work for most people. Isn't that expensive, FDA approved and good researched
Con: Permanent some side effect may occur (2% chance). Dropping DHT levels in the entire body, causes initial shedding. doesn't build density
Note: this option can be combined with all the products in level 1
Option B: RU58441 50/80 mg daily (1 ml 5% or 1 ml 8&)
Pros: should stop hair loss entirely, works at the cause, doesn't build (a lot of) density
Con: Kinda expensive, not FDA approved. There are some fear mongering side effects on forums, but my sources claims it safe. Takes some time to absorb
Note: Can be combined with all the products in level 1 and all in level 2 except CB-03-01. Alfratradiol can be added to further enhance the gainz.
Option C: CB-03-01 ( i don't know the dose, but clinically trials shows 2 times a day 7.5% is optimal)
Pros: FDA approved for hair loss, should stop the cause of hair loss
Con: expensive, long term side effects unknown, take some time to absorb.
Note: this option can be combined with all the products in level 1,and all products in level 2, but not with RU58441. Alfratradiol can be added to further enhance the gainz.
Option D: Minoxidil 1 ml a day
Pros: the best density builder out there, FDA approved and well researched
Con: greasy hair, only works for 40% of the people, need to used all life long the keep the hair gainz, collagen loss may occur and water retention
Note: this option can be combined with all the products in level 1 and 2. Dermastamping and retin A can be used for better results.
Level 3: To stop hardcore hair loss
Option A: 1 ml 8% RU58441, 0.5mg Dutasteride daily, 15% 1 ml Minoxidil with retin A
Pros: should stop DHT conversion and testosterone absorption while increasing density:
Con: many side effects may occur and costly
Option B: 1 ml 8% RU58441, 0.5mg Dutasteride 8% 1 ml Minoxidil with retin A, 25 mg Spironolactone
Pros: should stop hair loss 100%
Con: Price, Side effects like gyno, ed and brain from may occur.
Note: i will proof read everything later and perhaps do some edits and check grammar. If anyone sees something to change or see some mistakes message me and i will update the guide.
some tags:
@balding17yomanletcel
@Papabakvet
hello guys and welcome to my first guide, my ultimate anti hair loss guide. I am not a medical expert but like to research a lot. There are also a lot of scam products on the market that I want to point out. My main knowledge comes from Derek (YouTube More plates more dates) and Kevin (Kevin mann on YouTube). 2 of the most knowledge guys on YouTube that I know. Check them out. The missing info in this guide and explanation is searched on hair loss forums. Also fighting hair loss can be one of the most complex problems. There are people using trenbelone and still having perfect NW 0 hair and people crashing their DHT and T to almost female levels and still having massive hair loss.
table of content
- The 4 stages of hair growth
- Why do we get bald?
- How to know if you are balding?
- What hormones play a role in the development of hair and hair loss?
- What products that work are available?
- What scam / cope products are available?
- Plan to fight balding
The 4 stages of hair growth
To explain why hair loss occurs the 4 different cycles need to be explained.
The growth phase, or anagen phase, lasts an average of 3-5 years — so a full-length hair averages 18 to 30 inches
At the end of the anagen phase, your hair enters the catagen phase. This short transitional phase lasts approximately 10 days.
The telogen phase is a resting period of around 3 months, when strands remain in their follicles but are not actively growing.
Finally, strands are released from their follicles and fall out. Now the whole process can begin again!
Each hair follicle is independent and goes through the growth cycle at different times — otherwise all your hair would fall out at once! Instead, you only shed a certain number of hairs a day – 80 to 100 hairs on a healthy head of hair.
View attachment 719467
Why do we get bald?
The vast majority of men go bald because of a hereditary condition called androgenic alopecia. Depending on the sensitivity of male hormones in the hair-follicles. The Anagen phase get shorter and shorter till a permanent state of anagen phase is present and the hair follicle is deactivated. The strongest hormone that shorten the Anagen phase is DHT (dihydrotestosteron) and testosterone. Some woman are so sensitive to DHT and testosterone that the small amount they products is sufficient to cause massive hair loss and some male are genetically blessed that they can use superficial amounts of testosterone and still got perfect hair. in a later chapter i will go in depth on the different hormones that play a role in hair loss and hair growth.
Stress is a serious health problem that may cause hair loss. stress may cause shortage of the hair cycle, increased inflammation in the body, that causes the immune system to attack the hair follicle and destroy it. stress can also cause excessive hair pulling resulting in damage of the hair follicle. Since this form of hair loss is not genetic and is more formed by lifestyle and environment this guide wont cover stress related hair loss. Hair loss from stress generally is not permanent when stress is lessened.
if you are not genetically predisposed to hair loss by hormone sensitivity or overly stressed but still got receding hairline or thinning hair, your diet could be the cause. Since you need a really bad diet to get vitamins deficient when perfectly healthy and you shouldn't have an excuse to eat healthy i will give a summary of vitamins and minerals needed for healthy hair.
The following vitamins and minerals play an role in hair loss:
- Vitamin D
- Iron
- Biotin (B3)
- omega 3-6 ratio (1-3 ratio or lower causes lower inflammation in the body)
The following minerals need more research:
- Zinc
- Riboflavin (B2)
- B12
- Folic acid (B9)
By using an app like chronometer your macros (fat, protein and carbs) and micros (vitamins and minerals) can be seen. Important note, because an app says you have eaten certain vitamins and minerals it doesn't mean everything is absorbed, so deficient can still occur. Blood work is needed to analyse if certain deficiencies are present.
While most over the counter drugs are unlikely to cause hair loss, many prescription drugs can have a negative effect on hair. The following common drugs can cause hair loss:
- Oral retinoids like Accutane
- Antidepressant
- Thyroid medications
- Steroids (especially the DHT derivatives and some SARMS, RAD 140 is one of the strongest SARMS causing hair loss)
Bad lifestyle can also play a role. Lack of sleep causes lack of essential hormones needed for healthy hair. Smoking ca also be bad and high amount of uv-light also. This guide wont cover the lifestyle part.
Excessive hairstyles that pull the hair tight such as pigtails, cornrows or a tight cap can cause hair loss. Try to be as gently at the hair as possible. This guide wont go more in depth about this topic.
Another cause of hair loss is toxicity of certain metals like, thallium, mercury, selenium and colchicine. These kind of toxicity mainly occur when the liver isn't working properly, genetic defect that causes accumulation of these toxins or eating an high amount of these toxins. And dermatologist got a device to read the toxicity of the hair. This hair wont go more in depth about this topic.
The last reason hair loss can occur is a fungal infection also known as ringworm. Circles with bumps is being formed where hair is lost. In the picture below ringworm is shown. Antibiotics are needed to fight this disease. This guide wont cover ringworm since its rare to occur.
View attachment 717816
How to know if you are balding?
The human head contains around 100.000 and is the thickest and most dense at around 16. After that point the hair is slowly losing density and receding depending at the hair lost each day. Every day around 50-100 hairs enter the anagen phase and regrows, so its important to lose less hair then that to at least keep your currently density. Also hair can stay in telegon phase. That way the hairline is slowly receding. Most normies are noticing they are losing density when they got around 30.000 hair left.
Hair loss for males is measured in the Norwood scale. In the picture below the Norwood scale is measured. Hair loss can start from the crown, temples or general thinning called defuse thinning. The most common is a receding hairline at younger age while thinning. Later the temples start thinning heavenly. Till NW 1.5 is perfect without (small) PSL lose. After that its a PSL lose. Especially younger people think they are receding when they are like 17, but its more likely they got a big forehead so its looks like its receding.
View attachment 719465
An easy way to check if you are balding is to buy a hair catcher. That is a type of bath tube drain that is used to catch hairs while showering. Since you lose the most hair when you are showering or bathing it's the most accurate way to know your hair loss. When you lose below 40/70 hairs you're hairline and density should be maintained or improved. Above is worsening of the hair. You can also use a hair catcher to notice your hair loss treatment is working or not.
An professional way of measuring hair loss is the use of a device called a trichometer. This device measures in an area its cross-sectional area. The device is not abla to measure a receding hairline, but can measure loss of density. The device can also have a microscope to analyze the hair further. The device can also have a microscope to examine the hair further.
Another way used by dermatologist to measure if you are thinning is the hair loss test. Around 40 hairs is pulled at different spots. When 6 or more hairs are lost you got active hair loss. Normal values for the hair pull test should be reduced to 2 hairs or fewer (97.2% of participants). https://www.sciencedirect.com/science/article/pii/S0190962216308921
When 6 or more hairs are lost you should hop on treatment asap or do nothing and fall into just shave it bro meme.
What hormones play a role in the development of hair and hair loss?
This paragraph is added to get more in depth about hormones. Hormones play in important role in hair loss and some treatment result in a change of the hormone profile which can cause massive problems in some unlucky individuals. Also the reason why certain medicines work is better explained.
DHT
The biggest cause of hair loss and the strongest androgenic hormone is DHT.
Dihydrotestosterone (DHT) is an androgen hormone, a type of male sex hormone found in both men and women. Androgen's are responsible for biological male characteristics like body hair, increased muscle mass, and a deeper voice. How exactly DHT hair loss occurs isn’t fully understood, but it’s thought that DHT attaches to androgen receptors on the hair follicles. Then DHT causes the hair follicles to shrink. As a result, the anagen, or growing, phase of the hair growth cycle decreases in length, while the telogen, or resting, phase of the hair cycle is extended.
5ar is directly happening near the hair follicle causing DHT buildup. DHT is +- 5 times as strong against hair loss as testosterone.
Some important genetic traits that causes DHT related hair loss.
- More androgen receptors on the hair follicles
- Increased DHT levels in the body
- Higher sensitivity to androgens
View attachment 719605
Testosterone
Testosterone causes hair loss just as DHT. DHT is just 5 times as powerful so reducing DHT is usually enough to stop hair loss.
Cortisol
Cortisol is the stress hormone that causes the body to get in the fight or flight mode by directing as much as energy to vital organs. By extended time of the fight of flight mode the body gets depleted and inflammation occurs and causes degradation of cells. Since hair isn't vital its one of the first places where cell degradation occurs with hair loss as consequence. Hyaluronan and proteoglycans are important to skin elements that are responsible for hair growth. High cortisol levels reduce the synthesis and accelerate the degradation of these two skin elements almost by 40 percent, say researchers
Estradiol
Estradiol is a female hormone in the estrogen group. The hormone causes the hair to stay longer in the anagen phase. An increase in this hormone in males causes longer hair, but also less body hair. When Testosterone increases Estradiol also increases. Too much Estradiol may cause man-boobs.
Progesterone
Progesterone is another female hormone in the estrogen group. When Estradiol and progesterone ratio of off the hair gets thinner. Progesterone competes with 5ar to form DHT. when you get older less progesterone is formed so more DHT is formed resulting in hair loss.
Prolactin
Another female hormone. High amounts can cause hair loss. It's really rare for males and more common for females.
Thyroid hormones
Stem cells located at the bulges of the hair follicles are responsible for hair cycling and contribute to the regeneration of the new epidermis after wounding.
Thyroid hormone signaling is an important determinant of the mobilization of stem cells out of their niche in the hair bulge. Problems with thyroid hormones therefore
DHEA (Dehydro-epiandrosteron)
DHEA is a precursor to testosterone and estrogen. A low amount can cause hair loss, but it's really rare in males.
SHBG (sex-hormone-binding-glublin)
SHBG is a molecule that is comprised of carbohydrate and protein. The protein it contains is produced in the liver. Three different sex hormones bind to it. Estrogen, dihydrotestosterone (DHT), and testosterone are the hormones that bind with it. SHBG’s main job is to transport these hormones to various organs of the body. As SHBG has a stronger affinity for DHT and testosterone, it plays a crucial role in the maintenance of testosterone-estrogen balance in the female body. Problems with SHBG is rare.
PGD2
Another important Phospholipid is the PGD2. It works like a hormone on the body, but it isn't a hormone since it's a fat lipid and not a protein-like hormone. PGD2 is elevated in the scalp of bald people. PGD2 inhibits hair growth.
Some other functions PGD2 causes:
- Cause bronchial constriction during asthma attacks
- Increase drowsiness far more than any other internally created molecule
- Plays an integral role in allergic reactions such as eczema
- Increase inflammation
- Inhibit hair growth, especially in relation to male pattern baldness
photo of PGD2 and other lipids. duo max size of images i it didnt fit in.
PG e2
A lipid that helps hair growth and maintains certain PGD2 and PGF2a levels. It also promotes the relaxation of tissue.
PGF2a
A lipid that helps hair growth and maintains certain PGD2 and PGF2a levels. It works against anti-inflammation.
What products that work is available?
In this paragraph, we explain what products are available, how good they work, and how they work.
Finasteride
finasteride is a FDA-approved drugs for hair loss that works by inhibiting 5ar and lowering DHT (strongest hormone that causes hair loss) levels in the body. Finasteride drops DHT by around 50-70%. By inhibiting DHT testosterone raises and so does estrogen. Topical finasteride drops DHT more in the hair and less in the body causing fewer side effects. ED problems occurred in less than 2% of the males so do not get afraid of the sides and do some bloodwork beforehand. Finasteride is one of the most used and most researched anti-hair loss medicine. Finasteride stops hair loss but doesn't cause a lot of regrowth (reversal on the Norwood scale). Using Finasteride should cause an initial shed for a few months.
Dutasteride
Dutasteride is an FDA-approved drugs (not for hair loss) that lowers DHT by around 90% it works just like Finasteride by blocking 5ar conversion of testosterone. it is only used for severe cases of MPB due to the strong drop of DHT. It's also possible to use a topical Dutesteride solution. This drops all the DHT almost completely in the scalp and should stop MPBin most cases. Dutasteride is way stronger than Finasteride and causes more side effects. Wherever the chance of ED in Finasteride is around 2% it's 5% for Dutasteride.
Azelaic acid
Azelaic acid is a weak 5ar inhibitor. Some studies claim it is stronger than Dutesteride, however anecdotal a lot of people claim it doesn't work. Its also never used as a stand-alone product, so it may work in conjunction with other products.
Alfratradiol
Alfratradiol is a weak estrogen, but weak enough that it doesn't cause feminization at higher doses. It works like Finasteride by stopping the 5ar conversion of testosterone to DHT.
It's weaker than Minoxidil as a regrowth but also is a light anti-androgen, so it increases density and stops hair loss moderately in a more natural way. Alfratradiol mixes well with RU58441. It can be used in conjunction with Finasteride or Dutasteride.
Minoxidil
Minoxidil is the strongest hair builder currently available on the market. It promotes the Anagen phase of the hair cell by opening the calcium channels in the hair follicle causing more nutrients to go to the hair. Possible by interfering with the PGD2/ PG 2e and PGF2a levels, but the exact way Minoxidil works is unknown. A lot of users notice the loss of collagen when using Minoxidil. It´s however not clinically proven so it may be fear-mongering.
Minoxidil may not work for everyone since Minoxidil needs to be converted to Minoxidil sulfate on the scalp and some people are unable to do. Around 40% got enough sulfotransferase enzymes to make Minoxidil work, unfortunately. Minoxidil may cause a shed for a certain amount of months, so I would advise using it for some months before saying if it works or not works. Minoxidil can be used orally or topical. Orally improves hair in the entire body, like the beard, eyebrows, and eyelashes. The side effects are worse tough. Any gains gotten with Minoxidil will be lost when stopped Minoxidil. Minoxidil doesn't stop the root of hair loss, the hormones, so it shouldn't use as the first product.
Nanoxidil
Nanoxidil is a hair grower just like Minoxidil. Its molecule almost identical to Minoxidil so the same result should be expected. There is no research proving that Minoxidil is better than Nanoxidil, so it's just a exspensive Minoxidil.
Stemoxydine
Stemoxydine is some kind of stemcells used to decrease the catagen phase so it's less long inactive. The exact reason for its work is unknown. It's way weaker than Minoxidil but barely got any side effects, but it isn't researched that much. When sopping Stemoxydine the hair isn't going to fall out, however, its advised to keep continuing Stemoxydine. Because it works differently then Minoxidil they can be stacked. Its weaker then 2% minoxidil and doesn't cause an initial shed. Stemoxydine is a great product to add to increase the hair density.
Stemoxydine is great stackable with RU58441.
CB-03-01 (Breezula)
Breezula is an anti androgen that works differently then Finasteride en Dutesteride. CB-03-01 competes with testosterone and DHT in the hair follicle, so less androgenic hormones gets absorbed. CB-03-01 recently got FDA approved. Breezula barely goes systemic and doesn't cause a (massive) shedding. The success stories depends per person of anti anti androgen's. There are people with really bad hair loss, who claim 0 effect and people with massive shedding who are on Dutesteride who got rid of the male pattern baldness (possible because testosterone was the last source of baldness). Not many side effects should occur. On high doses 2 times a day 7.5% Breezula should be better then Finasteride.
RU58441
RU58441 is the stronger and non approved version of CB-03-01. RU58441 should work really well against hair loss. The side effects of RU58441 is kinda tricky. Derek from more plates more dates says its probably not RU58441 and Kevin Mann thinks its because of low test. On hair loss forums there are multiple people claiming Heart palpitations, bad sleep etc. from RU58441. Allot use high doses tough. The exact long side effects are unknown. Research about Anti androgenic and certain medicines says they only occur when the testosterone is low, and RU58441 shouldn't go systemic enough to lose androgenic hormones in the body. Research shows that RU58441 works better against hair loss then Finasteride.
Fluridil
Fluridil is an anti androgen like Breezula and RU58441. It doesn't go systemic and study's shows that its a strong anti androgen, perhaps stronger then RU58441. It also shouldn't go systemic since its a hydrofoob and it shouldn't get absorbed in blood. Fluridil is expensive. Fluridil isn't use allot. of people on hair loss forums claims it isn't working, but they also claim RU58441 or Finasteride isn't working with them so take that with a grain of salt.
Spironolactone
Spironolactone is a strong anti androgen used against hair loss. Its mainly used by females because it blocks testosterone production and its used by males at high dosses who are transitioning to female. Males at hair loss forums are using it and some are claiming great success, but it comes with high risk so i don't recommend using it.
Ketoconazol
Ketoconazol is anti inflammatory product and a small DHT blocker used to threat hair loss, anti inflammatory and fungal problems. It helps a little bit against hair loss, but isn't as strong as AR5 inhibitors or anti androgen's, but its almost side effect free. Because of the weakness allot of people claim it isn't working. Derek from More plates more Dates advice to use it as first product, but Kevinn man says it doesn't work, even tough there are some anecdotal evidences he knows.
MK677 / HGH
Mk677 / HGH increases IGF-1 levels that increases cellular regeneration. The lower the IGF-1 levels the higher the resting phase of the hair follicles, the lower the hair density. IGF-1 is needed for hair growth and when this level is too low even without testosterone and DHT you will still be shedding. When IGF-1 levels are sufficient using MK677 or HGH doesn't change any hair density or stop MPB. Derek from More plates More dates says that MK677 works to increase hair density, but its more anecdotally.
Dermarolling / dermastamping
Whend dermarolling or dermastamping small needles are inserted into the scalp. Stand alone it doesn't increase density or help against male pattern baldness, but in conjunction with Minoxidil or topical Finesteride it increases the absorption or other products. 1.5 mm should be used 1 time a week.
Oral castor oil
Oral castor oil is a growth promoter weaker then Minoxidil or Stemoxydine, but way cheaper. It works by raising PGE2 levels in the body. Its a cheap almost side effect free way (except perhaps some stomach issues) to increase hair density. 1ml a day is enough, but up to 2ml is possible without diminishing returns. Its also combined with 5ar inhibitors and anti androgens for better results.
Lactobacillus ATCC PTA6475
An experiment medicine used to treat baldness. Clinical trials shows it works wonderful on mice. its hard to get it and Derek from more plates more dates didnt see any difference. It may work, but more research and testing is needed.
Latanoprost
Latanoprost is used to treat high pressure inside the eye due to glaucoma, but research on monkeys showed it was the best density builder available, better then Minoxidil and RU58441. It works as a PGE2 raiser. its however hella expensive and the people who experimented with it, barely claimed good results. Its also hard to find it on the black market so they may be scammed. It isn't a good stand alone treatment but can be used in conjunction with other products. It got the same working as Minoxidil, but it doesn't work good.
Travoprost
Works the same as Latanoprost.
Bimatoprost
Works the same as Latanoprost. Its slightly more researched and used. Its almost as good as Minoxidil, some people claim better results then Minoxidil. It raises PG e2 levels, losing scalp tension and increasing hair density.
Corticosteroids
Corticosteroids are topical steroids used for anti inflammatory and immune disorders. It shouldn't be used to treat MPB.
Cetirizine
Cetirizine inhibits PGD2 increasing hair density. It also reduces inflammations and irritations on the scalp. Its currently being researched in Germany. It should cause allot of density increase like Minoxidil. Not more is known and its only being tested at this moment.
Adenosine
This medicine is used for people with bad cardiovascular disease and got many side effects. A side effect is increasing hair density. It increases the dermal papal cell in the hair follicle creating healthier and more hair. Its very expensive and its weaker then Minoxidil.
Redensyl
Topical Redensyl is a density builder and helps to increase the dermal papilla cells health of the hair (bottom of the hair root) and works good against inflammation. So the hair survival rate increases 12-24% research shows. Research at cellular level shows its way better as hair density builder then Minoxidil. It isn't researched enough to conclude how good it works. People on hair loss forums noticed that Redensyl increased the hair density, but not as good as Minoxidil. It doesn't contain any side effects so i guess its a good hair product stackable with other products. I don't see enough info to confirm is this product isn't snake oil. Also this products can be sold commercially so the dosage and ingredients may differ per product.
Retinoids
Retinoids helps absorption of topical solutions like Finasteride or Minoxidil by exfoliating the upper scalp layer. Retinoids can be put into topical solutions easily by dropping a little bit in the solution.
Topical PGE2
Very expensive and impractical way to increase hair density, that barely works. In the future there may be a better, cheaper and more absorpele version.
What scam / cope products are available?
Head message
Improving blood flow causes helps against hair loss bullshit. Otherwise medicine that improves blood flow like heart medicine should work better. Bald people got just as much blood flowing through their scalp as non bald people. Otherwise the scalp of bald people would bleed less then non bald people, that isn't the case.
Red light cap
The studies are too low quality to prove red light works against hair loss and no visual evidence. Also not enough anecdotal evidence. Seems like snake oil to me.
A Critical Assessment of the Evidence for Low-Level Laser Therapy in the Treatment of Hair Loss - PubMed
There are a number of unanswered questions about the optimum treatment regimen, including maintenance treatment and the long-term consequences of LLLT use. Moving forward, protocols should be standardized across trials. Moreover, it is recommended that future trials include visual evidence and...
pubmed.ncbi.nlm.nih.gov
Caffeine
The studies are industry funded. The head author is the same guy who is in the Alcapin comercials.
The only comparison didnt had an control group and didnt use a trichometer. Also concluded that it almost as strong as Minoxidil even anecdotally its proven otherwise.
It was industry funded and not reviewed by the industry.
An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% versus Minoxidil 5% Solution in Male Androgenetic Alopecia
Androgenetic alopecia is a condition with a high prevalence worldwide and affects both males and females. Currently, only 2 approved treatments exist: finasteride (males only) and minoxidil 2 or 5% solution (males and females).We conducted a randomized, ...
www.ncbi.nlm.nih.gov
PRP
Blood is taken en in a centrifuge split. Some growth stimulants is added.
The blood is injected in the scalp again.
Only 1 study and the follow up study concluded the research didn't show any evidence like photos Not proven en not enough anecdotal evidence suggesting it works, especially at that price comparing to like Finasteride and Minoxidil.
Platelet-Rich Plasma: Does It Work?
PRP is an interesting idea, but it has thumbs down from three major scientific reviews and counting.
www.painscience.com
Saw palmetto
There are some clinically studies proving the work of Saw palmetto. However the follow up study proves the study wasn't traceable enough and an comparison study noticed at was as effective as the placebo for prostate problems. DHT causes prostate problems so less problems should be noticed by using saw palmetto.
https://jamanetwork.com/journals/jama/fullarticle/1104439
Nutrafol
Overhyped scam product.
Peppermind oil
May work, but very minimal. Can cause irritation.
Peppermint Oil Promotes Hair Growth without Toxic Signs
Peppermint (Mentha piperita) is a plant native to Europe and has been widely used as a carminative and gastric stimulant worldwide. This plant also has been used in cosmetic formulations as a fragrance component and skin conditioning agent. This study ...
www.ncbi.nlm.nih.gov
In this paragraph, i am going to discuss different forms of hair loss treatment plans. It's written in different levels of hardcoreness.
level 1 (not a lot of side effects extra note: all the options can be combined in 1 since they are stand alone)
Option A:
1-2ml castor oil daily
Pros: cheap while building density
Con: stomach issues may occur. Not the best density builder. Won't stop the cause of hair loss. Is tasting terrible.
Option B:
Ketoconazol shampoo 10 min once every other day
Pros: side effect free, helps against inflammation and dandruff
Con: depending on the quality the hair may feel to dry (regenpure is high quality, i use like 1 bottle for a few months), may not work well and be cope ;/. Doesn't stop the cause of balding. Takes 10 min every other day to use.
Option C:
Stemoxydine once a day (Stemoxydine Neogenic Garnier Fructis is cheap, but haven't tested it myself if its good)
Pros: side effect free and almost as strong as Minoxidil 2% in good trials
Con: Don't stop balding cause no DHT/ test blocker
Option D:
Redensyl (i don't know the dose and price, couldn't find a lot of info about it)
Pros: side effect free, could be decent density builder
Con: Not allot of info founded about it cause its kinda unknown (at-least for me)
Level 2 side effects may occur, but it should be enough for most people to stop hair loss.
Option A: Finasteride 0.5-1 mg daily (topical or oral, topical is expensive or takes more time to make, but slightly better)
Pros: stops the cause of hair loss, should work for most people. Isn't that expensive, FDA approved and good researched
Con: Permanent some side effect may occur (2% chance). Dropping DHT levels in the entire body, causes initial shedding. doesn't build density
Note: this option can be combined with all the products in level 1
Option B: RU58441 50/80 mg daily (1 ml 5% or 1 ml 8&)
Pros: should stop hair loss entirely, works at the cause, doesn't build (a lot of) density
Con: Kinda expensive, not FDA approved. There are some fear mongering side effects on forums, but my sources claims it safe. Takes some time to absorb
Note: Can be combined with all the products in level 1 and all in level 2 except CB-03-01. Alfratradiol can be added to further enhance the gainz.
Option C: CB-03-01 ( i don't know the dose, but clinically trials shows 2 times a day 7.5% is optimal)
Pros: FDA approved for hair loss, should stop the cause of hair loss
Con: expensive, long term side effects unknown, take some time to absorb.
Note: this option can be combined with all the products in level 1,and all products in level 2, but not with RU58441. Alfratradiol can be added to further enhance the gainz.
Option D: Minoxidil 1 ml a day
Pros: the best density builder out there, FDA approved and well researched
Con: greasy hair, only works for 40% of the people, need to used all life long the keep the hair gainz, collagen loss may occur and water retention
Note: this option can be combined with all the products in level 1 and 2. Dermastamping and retin A can be used for better results.
Level 3: To stop hardcore hair loss
Option A: 1 ml 8% RU58441, 0.5mg Dutasteride daily, 15% 1 ml Minoxidil with retin A
Pros: should stop DHT conversion and testosterone absorption while increasing density:
Con: many side effects may occur and costly
Option B: 1 ml 8% RU58441, 0.5mg Dutasteride 8% 1 ml Minoxidil with retin A, 25 mg Spironolactone
Pros: should stop hair loss 100%
Con: Price, Side effects like gyno, ed and brain from may occur.
Note: i will proof read everything later and perhaps do some edits and check grammar. If anyone sees something to change or see some mistakes message me and i will update the guide.
some tags:
@balding17yomanletcel
@Papabakvet
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). I was already getting fed up with them posting "2 month mewing progress!! 
