O
Osie
Diamond
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Introduction:
There are many different factors that we’ve come to understand affect our IGF-1 levels. For example, eating in a caloric deficit. However, one thing that’s rarely discussed is liver function and how integral it is to the production of high IGF-1 levels. Today, that is exactly the thing we’ll be discussing!Why is optimal liver function important for IGF-1?:
Optimal liver function is vital for high IGF-1 levels because IGF-1 is primarily produced in the liver. Around 75% of our circulating levels of IGF-1 derive from our liver, which is a very significant amount. The liver also keeps homeostasis within the GH/IGF-1 axis, the hormonal axis that decides the vast majority of our height growth. Essentially, the liver controls the two biggest factors of growth, meaning that its health is very important.
What happens when liver function is suboptimal?
In any disease or scenario where liver dysfunction occurs, IGF-1 levels diminish very quickly. Liver dysfunction diseases like diabetes, hepatitis C, Alcoholic Liver Disease, and many others have all been proven to drastically lower people’s IGF-1 levels, presumably as a result of severe liver inflammation, damage, and scarring. Any form of liver dysfunction will negate potential IGF-1 production and GH/IGF-1 axis regulation, so if your blood test markers show that your liver isn’t running as well as it can, consider getting help.
How to optimize liver function?:
If you notice after a blood test that some of your liver markers (Albumin, Bilirubin, Prothrombin Time) and enzymes (ALT and AST) are out of wack and or are at unhealty places, I recommend supplmementing with these compounds:- Milk Thistle (300MG 3x a day)
- NAC (600MG)
- TUDCA (250 3x a day)
- Vitamin E (800IU)
- Selenium (200mcg)
Conclusion:
If you’ve noticed that your IGF-1 levels aren’t as high as you expect them to be despite supplementation or age, it could possibly be caused by subpar liver function. Invest in your liver health today if you care about increasing your IGF-1 levels!