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Iron
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There is a gene linked to high self esteem and optimism that reaches its peak frequency in black Africa.
pubmed.ncbi.nlm.nih.gov

Oxytocin receptor gene (OXTR) is related to psychological resources - PubMed
Psychological resources--optimism, mastery, and self-esteem--buffer the deleterious effects of stress and are predictors of neurophysiological and psychological health-related outcomes. These resources have been shown to be highly heritable, yet the genetic basis for this heritability remains...

Here, we report a link between the oxytocin receptor (OXTR) SNP rs53576 and psychological resources, such that carriers of the "A" allele have lower levels of optimism, mastery, and self-esteem, relative to G/G homozygotes.
