Kojo
18yo | 120mg Accutane | 2.5 Minox
- Joined
- Feb 7, 2026
- Posts
- 3,467
- Reputation
- 2,280
I just never understood why people are willfully ignorant knowing in their head they haven't done research or put effort into reading things they say??
This forum is genuinely so shit and is starting to piss me off every day. I come on here to help you ugly manlet incels as much as I can but everyone wants to act high iq as if they're einstein. If you're gonna do that at least have the knowledge to back it??
Even knowledge alone isn't enough, you need actual intelligence. Most retards with "knowledge" can't even interpret and deduct data properly without being fallacious or just have shit comprehension. So fucking annoying. People also think things are so black and white in such a complex niche like pharmacology/biology
ANOTHER THING/EXAMPLE:
Do people just not get the concept of receptors as a whole????
This shit is LITERALLY biology/pharmacology 101. I HATE people that think everything is just linearly efficacious. And people that harp on about levels so much.
"I don't have high test bro I'm not gonna be dimorphic" Whole time I was like almost hypogonadic in puberty yet I have projection in every facial bone. Whilst high T mfers still get no dimo gains but a pedo stache



Guys, molecules bind to receptors to activate them. Without receptors all of these ligands are effectively useless. Receptors ALSO have their own sensitivity levels that are genetically set (Can slightly be augmented environmentally).
This very simple concept can literally get so much of you so far with understanding shit and preventing useless arguments that help no one. You think someone like tyler maher or oliver oconnor are only like that because "muh high test" or was it there genetic predisposition to have really sensitive receptors in bones to sex steroids.
The second screenshot was me explaining why retinoid concentration doesn't matter that much and doesn't always yield more results. Potentially just ridding you with irritation for zero reason.
This SAME concept applies to my recent minoxidil threads.
This forum is genuinely so shit and is starting to piss me off every day. I come on here to help you ugly manlet incels as much as I can but everyone wants to act high iq as if they're einstein. If you're gonna do that at least have the knowledge to back it??
Even knowledge alone isn't enough, you need actual intelligence. Most retards with "knowledge" can't even interpret and deduct data properly without being fallacious or just have shit comprehension. So fucking annoying. People also think things are so black and white in such a complex niche like pharmacology/biology
ANOTHER THING/EXAMPLE:
Do people just not get the concept of receptors as a whole????
This shit is LITERALLY biology/pharmacology 101. I HATE people that think everything is just linearly efficacious. And people that harp on about levels so much.
"I don't have high test bro I'm not gonna be dimorphic" Whole time I was like almost hypogonadic in puberty yet I have projection in every facial bone. Whilst high T mfers still get no dimo gains but a pedo stache
Guys, molecules bind to receptors to activate them. Without receptors all of these ligands are effectively useless. Receptors ALSO have their own sensitivity levels that are genetically set (Can slightly be augmented environmentally).
This very simple concept can literally get so much of you so far with understanding shit and preventing useless arguments that help no one. You think someone like tyler maher or oliver oconnor are only like that because "muh high test" or was it there genetic predisposition to have really sensitive receptors in bones to sex steroids.
The second screenshot was me explaining why retinoid concentration doesn't matter that much and doesn't always yield more results. Potentially just ridding you with irritation for zero reason.
This SAME concept applies to my recent minoxidil threads.
@nwed @appealisLAW @avgsub5human @Paul.jnxy
