Newday*V3
Iron
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- Jan 13, 2024
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Someone explain pls, i tried to jump on the hype train ages ago taking 3g a day of aspirin and I have no idea why. Wtf does it do outside of being a painkiller
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let natural selection do its coursei tried to jump on the hype train ages ago taking 3g a day of aspirin
JoinedJan 13, 2024
and I have no idea why.
you have autism
Wtf does the “V3” mean in my name retard take a guessi tried to jump on the hype train ages ago taking 3g a day of aspirin
JoinedJan 13, 2024
and I have no idea why.
you have autism
Still waiting on full text link to the study this excerpt is from.“Non-selective COX inhibitors including aspirin, ibuprofen and flurbiprofen accelerated the senescence.”
So aspirin is just lowers inflammation?Idk but here’s my notes on aspirin
Why Do Some People Bleed From Aspirin Even When Taking Vit. K? The Vascular And Vitamin C Connection | Ray Peat Forum
The Effect of Low‐Dose Daily Aspirin Intake on Survival in the Finnish Centenarians Cohort - Agüero‐Torres - 2001 - Journal of the American Geriatrics Society
Why Aspirin Goes Best With Bicarbonate and Glycine | Chris Masterjohn Lite #99
COX is an enzyme which promotes the activation of inflammatory processes, but also the resolution of those processes. COX inhibitors reduce the magnitude of the peak of the inflammatory process but also inhibit the resolution, and are thereby able to promote chronic low-grade inflammation.
Aspirin (specifically the acetyl group) modifies COX so that the increase in inflammation by COX is bypassed and while the resolution of the inflammatory process occurs. After the acetyl does this work, the salicylate remains. Salicylate, however, is not a COX modifier but a COX inhibitor. Glycine can neutralize salicylate, and because of this salicylate depletes glycine. Higher urine pH promotes excretion of salicylate via the urinary route.
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner - ScienceDirect
“Non-selective COX inhibitors including aspirin, ibuprofen and flurbiprofen accelerated the senescence.”
“As for the cellular senescence, aspirin inhibited senescence of human endothelial cells, whereas indomethacin accelerated it. In this case the inhibitors were found to regulate senescence via modulation of nitric oxide and ROS generation and not via inhibition of COX catalytic activity (Bode-Böger et al., 2005).”
Not that simple watch the Chris masterjohn video in my notesSo aspirin is just lowers inflammation?
enhancementAspirin doesnt occur in nature so why would you even eat it
what enchancement niggaenhancement
I have no idea that y i am askingwhat enchancement nigga
Only low quality studies show Fish oil or omega 3 being good. Fish oil will age you.Aspirin has benefits, but their short-lived and long-term said benefits will basically reverse, giving the opposite effect.
And why is raypeat so heavy in these forums?
Someone just said omega-3s are bad JFL.
All the studies point to the opposite.
And it’s all thrown into the trash because a dude named Raypeat said so.View attachment 2685225
Salicylates do, aspirin is acetylsalicylate, and the acetyl group actually has the benefit of modifying COX enzyme as to reduce inflammationAspirin doesnt occur in nature so why would you even eat it
Only low quality studies show Fish oil or omega 3 being good. Fish oil will age you.
Salicylates do, aspirin is acetylsalicylate, and the acetyl group actually has the benefit of modifying COX enzyme as to reduce inflammation
They are low quality because they imply omega 3 is good. I haven’t read ‘em.How are you so confident to say these studies are low quality? Can you explain I am confused
so no omega 3s from iherb thenThey are low quality because they imply omega 3 is good. I haven’t read ‘em.
Read this, very great article you’ll understand.
Also, fish oil shorted mouse lifespan. (Makes sense once you understand how PUFAs are highly prone to lipid peroxidation and are the precursors to prostaglandins)
Fight Aging By Replacing PUFAs With SFAs And MUFAs (Study Analysis)
High PUFA fat sources decrease lifespan compared to lard (high MUFA and high SFA) in mice on a calorie restricted diet “Life span was also increased (p < .05) in the CR lard mice compared to animals consuming either the CR fish or soybean oil diets. These results indicate that dietary lipid...looksmax.org
I’ve taken fish oil in the past after hearing Jew propaganda, probably aged me a ton. At least now I hopefully learned to actually look into and think about things before supplementing, I greatly regret takeing the cod liver oil.so no omega 3s from iherb then
Did you stick your finger up your butt while taking that aspirin? Even just a little bit?Someone explain pls, i tried to jump on the hype train ages ago taking 3g a day of aspirin and I have no idea why. Wtf does it do outside of being a painkiller
huh?Did you stick your finger up your butt while taking that aspirin? Even just a little bit?
Animal studies are great - but this is not one of them.Also, fish oil shorted mouse lifespan. (Makes sense once you understand how PUFAs are highly prone to lipid peroxidation and are the precursors to prostaglandins)
What is the significance of the article you linked?Animal studies are great - but this is not one of them.
Mice did not evolve on fish.
and with regards to the peroxidation note:
Age-dependent changes in lipid peroxide levels in peripheral organs, but not in brain, in senescence-accelerated mice - PubMed
The tissue concentration of lipid peroxides was determined in the brain, heart, liver, lung and kidney of accelerated senescence-prone (SAMP-8) and -resistant (SAMR-1) mice at 3, 6 and 9 months of age by a method involving chemical derivatization and high performance liquid chromatography. The...pubmed.ncbi.nlm.nih.gov
Read this, very great article you’ll understand.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527634/
so much high Iq shit about omega 3 i cant comprehendWhat is the significance of the article you linked?
its not hard to comprehend you just have to read. Do you even know what omega 3 is?so much high Iq shit about omega 3 i cant comprehend
fatty acid that is abundant in fish and sum nuts. thats all i know…its not hard to comprehend you just have to read. Do you even know what omega 3 is?
It’s a PUFA. PUFA bad.fatty acid that is abundant in fish and sum nuts. thats all i know…
White willow bark you numbnuts idiot. its nearly the exact same as aspirinAspirin doesnt occur in nature so why would you even eat it
suck my ugly indian cock faggotWhite willow bark you numbnuts idiot. its nearly the exact same as aspirin
White willow bark you numbnuts idiot. its nearly the exact same as aspirin
where do you think the SALICYLIC ACID comes from you poojeet currry
JflAspirin doesnt occur in nature so why would you even eat it
and with regards to the peroxidation note:
Age-dependent changes in lipid peroxide levels in peripheral organs, but not in brain, in senescence-accelerated mice - PubMed
The tissue concentration of lipid peroxides was determined in the brain, heart, liver, lung and kidney of accelerated senescence-prone (SAMP-8) and -resistant (SAMR-1) mice at 3, 6 and 9 months of age by a method involving chemical derivatization and high performance liquid chromatography. The...pubmed.ncbi.nlm.nih.gov
Animal studies are great - but this is not one of them.
Mice did not evolve on fish.
and with regards to the peroxidation note:
Age-dependent changes in lipid peroxide levels in peripheral organs, but not in brain, in senescence-accelerated mice - PubMed
The tissue concentration of lipid peroxides was determined in the brain, heart, liver, lung and kidney of accelerated senescence-prone (SAMP-8) and -resistant (SAMR-1) mice at 3, 6 and 9 months of age by a method involving chemical derivatization and high performance liquid chromatography. The...pubmed.ncbi.nlm.nih.gov
But this all-or-nothing Ray Peat mindset is stupid considering the dude broke his own rules.
i tried to jump on the hype train ages ago taking 3g a day of aspirin and I have no idea why
I done it because i thought it will change my eye colour jfl even worsepeatmaxxed incels at it again jfl
they never learn
why not take it for 4-5 days and make a break for a week and repeat?Aspirin has benefits, but their short-lived and long-term said benefits will basically reverse, giving the opposite effect.
And why is raypeat so heavy in these forums?
Someone just said omega-3s are bad JFL.
All the studies point to the opposite.
And it’s all thrown into the trash because a dude named Raypeat said so.View attachment 2685225