Why fearmongering about AI doses is idiotic (TL;DR, don't worry about low estrogen)

[Deleted member 23391]

Because in someone without a suppressed HPTA (normal, functioning testicles) the testicles will continue to produce estrogen from intratesticular testosterone. This can NOT be stopped by aromatase inhibitors because aromatase is expressed in the leydig cells where testosterone is produced, so even if the AI crosses the blood-testis barrier it won't do much since the enzyme is converting testosterone to estrogen locally in the same cell (paracrine effect). The ONLY time you have to worry about severely crashed estrogen levels to the point where it would be a problem is when you have a shutdown HPTA, usually from taking exogenous sex steroids (less likely: long-term opiate abuse, etc). Then the testicles are not producing adequate testosterone, and hence estrogen.

All this theoryceling about low estrogen, brain damage, being unable to get an erection, etc from aromatase inhibitors is fucking retarded and based on theories and anecdotes from roid forums full of idiots that refuse to use hCG to preserve the function of their testicles. So to the heightmaxxers, no, you are not going to die from taking 0.5mg of arimidex/12.5mg of aromasin a day.

 

[Maxxwell]

I thought you were talking about AI technology at first jfl

 

[Deleted member 23391]

The point is that as a normal male that either

A) doesn't take steroids
B) does take steroids, but uses hCG, as EVERY MAN ON STEROIDS SHOULD

you will always have a baseline level of estradiol produced by your testicles uninhibited by AI usage that will prevent it from being so low to the point where it would be genuinely detrimental to your health

 

[bishōnenmaxxer]

I thought you were talking about AI technology at first jfl

 

[chadcel;]

Tfw AI not only takes your job but your estrogen too

 

[adungonu55]

Because in someone without a suppressed HPTA (normal, functioning testicles) the testicles will continue to produce estrogen from intratesticular testosterone. This can NOT be stopped by aromatase inhibitors because aromatase is expressed in the leydig cells where testosterone is produced, so even if the AI crosses the blood-testis barrier it won't do much since the enzyme is converting testosterone to estrogen locally in the same cell (paracrine effect). The ONLY time you have to worry about severely crashed estrogen levels to the point where it would be a problem is when you have a shutdown HPTA, usually from taking exogenous sex steroids (less likely: long-term opiate abuse, etc). Then the testicles are not producing adequate testosterone, and hence estrogen.

All this theoryceling about low estrogen, brain damage, being unable to get an erection, etc from aromatase inhibitors is fucking retarded and based on theories and anecdotes from roid forums full of idiots that refuse to use hCG to preserve the function of their testicles. So to the heightmaxxers, no, you are not going to die from taking 0.5mg of arimidex/12.5mg of aromasin a day.

agree but also dont overdo it
i went fucking schizo on letrozole

 

[Deleted member 23391]

agree but also dont overdo it
i went fucking schizo on letrozole

it probably fucked your HDL too

 

[adungonu55]

it probably fucked your HDL too

Nah i took blood tests, only thing that was off was platelet count

 

[Deleted member 23391]

You have stupid roiders blasting neurotoxins like deca and tren at 500mg+/wk and raping their livers with superdrol who are scared to take half an arimidex pill now because they think it will give them brain damage from watching More Plates More Dates, LOL. Let's stop with the foolishness please.

 

[ricetard]

agree but also dont overdo it
i went fucking schizo on letrozole

How often were you taking this shit lol

 

[adungonu55]

How often were you taking this shit lol

1mg EOD

 

[ricetard]

1mg EOD

pretty normal then I think

someone on this site started taking 75-100mg weekly and closed their growth plates within weeks

 

[adungonu55]

pretty normal then I think

someone on this site started taking 75-100mg weekly and closed their growth plates within weeks

that much letrozole would kill you bruh

 

[ricetard]

It was aromasin but the same thing probs would’ve happened

that much letrozole would kill you bruh

they’re 5’4 so they’re probably going to kill themselves one way or another