Why HGH is cope and will NOT work for you!!!! (HGH USERS GTFIH!!!)

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

 

[domdadon]

Genes determine the number of chondrocytes in the growth plates, how fast they divide, how long plates stay open, sensitivity to gh, and timing of puberty. So that means a maximum height is genetically limited.
You can still absolutely optimize conditions so those condrocytes divide longer, more efficiently, and delay exhaustion and growth plate closure. Things that affect these condrocytes are gh and igf-1 levels, estrogen exposure, nutrition,sleep and overall health.
When people talk about growing taller with hgh here some retards think blastin that shit while being like 5’6 at 16 will magically growth them to 6ft, which is not what happens. The studies you cited weren’t even using enough gh and likely wasn’t implementing aromaste inhibitors which is needed to keep the growth plates open while you actually grow faster. Reasonably there’s a bone age limit where no sort of peptide will seriously help with height but it’s not impossible to say with a good hgh+ai cycle you can’t squeeze in some extra cm. Like let’s say you start gh at 15 sharp and you’re 5’7, you’ll probably be 5’9-5’11 no intervention but gh can realistically push that up to 5’10-6’1. Of course this is assuming optimal conditions and blood tests. Most dumbasses here won’t reap any benefit from pinning hgh. A real cycle that would help would be very expensive for the avg highschooler

Mirin thread tho

What do you consider a "real cycle" when money isnt a problem

 

[Ahmed88]

What do you consider a "real cycle" when money isnt a problem

How about 4 cycles of osteotomies in both tibia 5cm each and both femurs 7 cm each NIGGA

 

[domdadon]

How about 4 cycles of osteotomies in both tibia 5cm each and both femurs 7 cm each NIGGA

No correlation how do you go from peps to surgeries

 

[Ahmed88]

No correlation how do you go from peps to surgeries

It was a joke, nigger

No ,,pep" or any compound for that matter is increasing your height

If money is not a problem, LL would do the trick

 

[Spanish_slayer]

If HGH does not have any real effect based on these evidences, are peptides and other compounds that in theory make the pituitary gland excrete gh ( CJC, ipa and more) useless or do they produce an overall greater gh amount compared to what a teen would naturally excrete?

 

[Ahmed88]

If HGH does not have any real effect based on these evidences, are peptides and other compounds that in theory make the pituitary gland excrete gh ( CJC, ipa and more) useless or do they produce an overall greater gh amount compared to what a teen would naturally excrete?

Also cope

Rep me

 

[Spanish_slayer]

Also cope

And what is not cope, apart from surgical intervention?

 

[Ahmed88]

And what is not cope, apart from surgical intervention?

For bone growth and height? Nothing
For physique? Roids

Rep me nigger

 

[LGG]

shit thread explain giganticism then nigga

 

[Ahmed88]

shit thread explain giganticism then nigga

I explained this multiple times in this thread, Its a fucking Tumor nigga, use ur fucking brain, we haven't even studied the tumor fully for fucks sake

 

[LGG]

I explained this multiple times in this thread, Its a fucking Tumor nigga, use ur fucking brain, we haven't even studied the tumor fully for fucks sake

tumour which makes you produce more hgh... nigga...

 

[Ahmed88]

tumour which makes you produce more hgh... nigga...

A unstudied tumor which produces continuous amounts of hgh 24/7 that lead to acromegaly

Ur argument is basically saying
,,Give urself gigantism to get taller"

Retarded faggot

 

[LGG]

A unstudied tumor which produces continuous amounts of hgh 24/7 that lead to acromegaly

Ur argument is basically saying
,,Give urself gigantism to get taller"

Retarded faggot

its known u can hypothetically give yourself "acromegaly-like effects" when you abuse high doses or gh for years so i dont see why you couldnt give urself "giganticism-like effects" if done during puberty , listen while sure they havent done studies on normal people taking hgh to grow taller for obvious reasons, i think its pretty silly to think it wont increase your height, its well studied and been around for ages, countless anecdotes etc, also essentially all the tumour gives is a supraphysiological amount of igf 1 even if more sustained whatver, its still a similar state with exogenous use

 

[Ahmed88]

its known u can hypothetically give yourself "acromegaly-like effects" when you abuse high doses or gh for years so i dont see why you couldnt give urself "giganticism-like effects" if done during puberty , listen while sure they havent done studies on normal people taking hgh to grow taller for obvious reasons, i think its pretty silly to think it wont increase your height, its well studied and been around for ages, countless anecdotes etc, also essentially all the tumour gives is a supraphysiological amount of igf 1 even if more sustained whatver, its still a similar state with exogenous use

Did you even realize the point of my argument?

I never said its impossible to give urself ,,acromegaly or gigantism like effects"

You're dodging my arguments and just attacking with different arguments which have nothing to do with the previous points

You're basically saying ,,give urself gigantism and bypass your body's restrictions, so you get taller"

Even if it was theoretically possible to give urself gigantism from exogenous HGH, the ROI would be negative

Not only do you get multiple side effects (like facial deformities, and unaesthetic appearances) but you essentially die sooner

 

[LGG]

Did you even realize the point of my argument?

I never said its impossible to give urself ,,acromegaly or gigantism like effects"

You're dodging my arguments and just attacking with different arguments which have nothing to do with the previous points

You're basically saying ,,give urself gigantism and bypass your body's restrictions, so you get taller"

Even if it was theoretically possible to give urself gigantism from exogenous HGH, the ROI would be negative

Not only do you get multiple side effects (like facial deformities, and unaesthetic appearances) but you essentially die sooner

so your arguments are what? that we dont know how the tumour works? i dont understand i think we can draw the conclusions that tumour overproduces hgh -> supraphysiological igf 1 -> taller stature. also sure you can't give urself acromegaly or giganticism realistically, cause thats gonna be 24/7 production whereas with exogenous is just gonna be an injection with the spike for a few hours whatever and also the unaesthetic appearance is more with acromegaly, but my point is you are technically bypassing your bodys restrictions let alone with exogenous gh not neccessarily giganticism because you are giving urself more hgh than u naturally could produce, which is the same as in those conditions as giganticism to some extent

 

[Ahmed88]

so your arguments are what? that we dont know how the tumour works? i dont understand i think we can draw the conclusions that tumour overproduces hgh -> supraphysiological igf 1 -> taller stature. also sure you can't give urself acromegaly or giganticism realistically, cause thats gonna be 24/7 production whereas with exogenous is just gonna be an injection with the spike for a few hours whatever and also the unaesthetic appearance is more with acromegaly, but my point is you are technically bypassing your bodys restrictions let alone with exogenous gh not neccessarily giganticism because you are giving urself more hgh than u naturally could produce, which is the same as in those conditions as giganticism to some extent

Yes my arguments are that we don't know how the tumor (a medical disease) works, it is medically unjustified to assume injecting exogenous HGH is the same as a tumor, secreting GH 24/7, ignoring ur bodys mechanisms and keeping levels chronically high

gigantism and acromegaly are practically the same

Height sets the limit, you can NOT pass genetic limits

 

[LGG]

Yes my arguments are that we don't know how the tumor (a medical disease) works, it is medically unjustified to assume injecting exogenous HGH is the same as a tumor, secreting GH 24/7, ignoring ur bodys mechanisms and keeping levels chronically high

gigantism and acromegaly are practically the same

Height sets the limit, you can NOT pass genetic limits

well u can atleast pass it with aromatase inhibitors even if u say hgh wont work
giganticism is different because during development most of this high hgh and igf 1 is gonna go towards longitudinal bone growth and with acromegaly it will enlarge and thicken everything. but anyways sure im aware that exogenous gh is not the same as tumour cause secretion is different

Still, injecting exogenous hgh is still somewhat bypassing body mechanisms because it bypasses the negative feedback loop and somatostatin because ur directly injecting it, also the same way a tumour secretes 24 hours a day, on always, and how thats different to normal hgh release, which is intravenous and half life is 20-30 minutes, exogenous of course isnt on all the time, but the secretion is still different to endogenous gh as it gets released into bloodstream for a few hours which means the igf 1 is gonna be more sustained and it keeps it high for longer even if not "chronically" and again i think we do know how the tumour works enough to make an educated assumption on how it does increase height, as i said in my last reply, both lead to supraphysiological levels therefore taller stature

 

[Ahmed88]

well u can atleast pass it with aromatase inhibitors

You need to nuke your e2 to achieve what ur saying, also Estrogen is important for brain, bones and height

Still, injecting exogenous hgh is still somewhat bypassing body mechanisms because it bypasses the negative feedback loop and somatostatin because ur directly injecting it

Partially true but overstated
Your body still responds downstream

also the same way a tumour secretes 24 hours a day, on always, and how thats different to normal hgh release, which is intravenous and half life is 20-30 minutes, exogenous of course isnt on all the time, but the secretion is still different to endogenous gh as it gets released into bloodstream for a few hours which means the igf 1 is gonna be more sustained and it keeps it high for longer even if not "chronically"

Partially true again
They don’t recreate continuous exposure, which is what drives pathological overgrowth in gigantism and acromegaly

That's a huge difference

again i think we do know how the tumour works enough to make an educated assumption on how it does increase height, as i said in my last reply, both lead to supraphysiological levels therefore taller stature

We do know how tumors work to some extent, but we don't know all of it

Again, ur comparing 6iu-12iu of HGH to Acromegaly

Alot of people here do NOT want to develop acromegaly, the ,,evidence and assumptions" u showed, just prove what happens when ur body is broken and has a disease ridden tumor

But if you want to be the guinea pig go ahead and give urself acromegaly with exogenous HGH

 

[LGG]

You need to nuke your e2 to achieve what ur saying, also Estrogen is important for brain, bones and height


Partially true but overstated
Your body still responds downstream

Partially true again
They don’t recreate continuous exposure, which is what drives pathological overgrowth in gigantism and acromegaly

That's a huge difference



We do know how tumors work to some extent, but we don't know all of it

Again, ur comparing 6iu-12iu of HGH to Acromegaly

Alot of people here do NOT want to develop acromegaly, the ,,evidence and assumptions" u showed, just prove what happens when ur body is broken and has a disease ridden tumor

But if you want to be the guinea pig go ahead and give urself acromegaly with exogenous HGH

welp theres no data on non deficient kids so obviously we arent really gonna come to a conclusion, but yeah last things id say is probably not realistic or possible to give urself acromegaly with hgh and on regards to aromatase inhibitors sure we dont have any follow up studies on brain development after clinical trials on kids using anastrazole or whatever for height, but it seemed like it wasnt clinically significant enough for them to stop any studies cause of concerns on brain development, and also most arent very potent at crossing blood brain barrier and the local estrogen in brain is gonna be the main thing for brain development so it atleast doesnt touch the local e2 that much, and cause again blood testes barrier we will always have some e2 it wont really get "nuked" unless ur a women tbh.

 

[fractual]

What do you consider a "real cycle" when money isnt a problem

Limb lengthening maxillary downgraft gonion, mandible and zygo implants, genioplasty (projection), canthopexy, rhino, orbital implants

 

[narrowmouthcel]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

@iblamethebulk

 

[iblamethebulk]

@iblamethebulk

Shut up

 

[seal_1]

so what does work?

 

[Ahmed88]

so what does work?

Surgery
Nice pfp

 

[seal_1]

Surgery
Nice pfp
View attachment 4878599

thanks man but doesnt aromatase stop plate closure or Halotestin?

 

[narrowmouthcel]

Shut up

get off hgh and order tren

 

[percslikemolly]

thanks man but doesnt aromatase stop plate closure or Halotestin?

nah if you sean o pry them open they cant close

 

[Ahmed88]

thanks man but doesnt aromatase stop plate closure or Halotestin?

Not unless you nuke your e2 down to the fucking ground

Also, e2 is important for libido, bones and brain (and sometimes height)

 

[seal_1]

nah if you sean o pry them open they cant close

nice insult mitch, got me there

 

[percslikemolly]

nice insult mitch, got me there

posted at 3:33am

 

[seal_1]

posted at 3:33am

Welcome to ORG son, we dont sleep here.