Why HGH is cope and will NOT work for you!!!! (HGH USERS GTFIH!!!)

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

 

[tomacōck]

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

1if U = mg, then 1mg/kg/week is a good dose, but n=8 and the study is 32yo, JFL

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

0.5IU/kg/week. That's 4IU/dsy for a 60kg boy. Tanner 3-4 children have natural production ~= 5.4IU/day.

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

Same study as 1

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed

Again 0.5IU/kg/week, low dose

 

[tomacōck]

Mate, the dosages were perfectly fine
40-50kg person= 6-8iu in one study, 3-4 iu in the other
80kg person= 12-16iu and 6-8iu

Only in 1 super old study with n<10

I have no clue wtf GSS means the only GSS ik is Gerstmann-Sträussler-Scheinker syndrome

Genetic Short Stature

 

[dkolebp]

Mate, the dosages were perfectly fine
40-50kg person= 6-8iu in one study, 3-4 iu in the other
80kg person= 12-16iu and 6-8iu


I have no clue wtf GSS means the only GSS ik is Gerstmann-Sträussler-Scheinker syndrome






, no evidence=not a valid claim

yea im glad we both can argueee you're reetarded also 8ius is still kinda low

 

[dkolebp]

yea im glad we both can argueee you're reetarded also 8ius is still kinda low

agree**

 

[tomacōck]

Dosage in studies is too low.
Go check GSS studies

As well as those kids were far prepubertal so it'd be improper to evaluate upon those

 

[Ahmed88]

1if U = mg, then 1mg/kg/week is a good dose, but n=8 and the study is 32yo, JFL

No clue what you're talking about n=8 what?

The dose was fine, i don't understand what you're talking about

One might even argue a dose of 1iu/kg might even be too high, jfl

0.5IU/kg/week. That's 4IU/dsy for a 60kg boy. Tanner 3-4 children have natural production ~= 5.4IU/day.

Right, one study out of the two listed
HGH is dose dependent, i thought thats basic knowledge?

Also where are you getting 5.4 iu from?


Even then Endogenous HGH can NOT be compared to exogenous HGH, what?

Again 0.5IU/kg/week, low dose

No

Only in 1 super old study with n<10

WTF DOES N MEAN MATE

Genetic Short Stature

I found no studies showing increase in FAH

 

[tomacōck]

No clue what you're talking about n=8 what?

The dose was fine, i don't understand what you're talking about

One might even argue a dose of 1iu/kg might even be too high, jfl

Right, one study out of the two listed
HGH is dose dependent, i thought thats basic knowledge?

Also where are you getting 5.4 iu from?


Even then Endogenous HGH can NOT be compared to exogenous HGH, what?

No

WTF DOES N MEAN MATE

I found no studies showing increase in FAH

How can you not know what N is and claim you can read studies
and the kids are <10yo as well in the only proper dose study

 

[Ahmed88]

How can you not know what N is and claim you can read studies

I'm not asking, what N means, im asking what YOU mean by N:

N has different meanings.
People
Samples
Responders
Experimental runs
Blood pressure
In equations, n is just a variable meaning total count

kids are <10 in the only proper dose study

Right, again is this supposed to be a bad thing? This is an optimal age, lmao

Also study age here has no impact on the evidence/conclusion of the study


You're just throwing around nonsense

 

[tomacōck]

Right, again is this supposed to be a bad thing? This is an optimal age, lmao

Also study age here has no impact on the evidence/conclusion of the study


You're just throwing around nonsense

You're stupid I'm not willing to debate you because of this if you don't see the difference between a 4-10 yo and a 14+ yo

 

[olofin]

So how do i increase my height bro

you don't

 

[160cmcurry]

water

 

[Ahmed88]

water

This would be obvious information, if the average iq in here was above 90, sadly it isn't tho

 

[shitgoeswrong]

 

[crn]

yes and thats why kids with gigantism grow to 7 feet and people with aromatase deficiencies grow to 200cm

 

[Ahmed88]

yes and thats why kids with gigantism grow to 7 feet and people with aromatase deficiencies grow to 200cm

Muh gigantism saar

How are you verified and this retarded

 

[crn]

Muh gigantism saar

How are you verified and this retarded

instead of just adding muh and sarr can you actually explain why in otherwise healthy kids who have gigantism grow so tall?

 

[Ahmed88]

instead of just adding muh and sarr can you actually explain why in otherwise healthy kids who have gigantism grow so tall?

Okay let me get this right?
You want me to explain why someone with a tumor in their brain that releases HIGH DOSES OF HGH 24/7, bypasses their hypothalamic-pituitary feedback loop, is barely researched, and comes alongside other endocrine abnormalities, is the same as a normal kid injecting HGH?

Really?

@Master why are you verifying niggas like this

 

[boneridden]

A lot of People continue to believe that healthy children who lack growth hormone deficiency will experience height increases through HGH injections.

It won’t.

Why?

Let’s get into this


1. How Growth Hormone Actually Works

Spoiler: How Growth Hormone Actually Works

Human growth hormone (HGH), also called somatotropin, is a hormone that the pituitary gland, which is about the size of a pea and found at the base of your brain, makes and releases

Its main job?

Human growth hormone triggers growth in almost every tissue and organ in your body. It’s mostly known for its growth-promoting effect on cartilage and bone, especially in puberty. Cells in cartilage called chondrocytes and cells in bones called osteoblasts, receive signals from HGH to increase replication and thus allow for growth in size.

2. What the Studies ACTUALLY Show

Spoiler: What the studies ACTUALLY show

People often cite studies claiming “HGH increases height.” Let’s clarify what these studies actually studied.

Most research involves children who are GH-deficient children who cannot produce normal levels of GH due to medical conditions. Examples:

• Short and Long-Term Effects of Growth Hormone in Children and Adolescents With GH Deficiency
• Use of growth hormone in children with GHD
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• National Cooperative Growth Study: 25 Years of Growth Hormone Data, Insights, and Lessons for Future Registries
• Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort
• Effect of different doses of recombinant human growth hormone therapy on children with growth hormone deficiency: a retrospective observational study
• Long-term Response to Recombinant Human Growth Hormone Therapy in Indian Children with Growth Hormone Deficiency

VERY Important: These studies are on children who are medically short due to GH deficiency, and do NOT produce enough HGH not normal kids. The effect is correcting a deficiency, not surpassing genetic potential.



Some other studies explore ISS (Idiopathic Short Stature):

• Long-term results of growth hormone therapy in children with idiopathic short stature, subnormal growth rate and normal growth hormone response to secretagogues. Dutch Growth Hormone Working Group
• THE IMPACT OF DOSAGE ON THE EFFECT OF GROWTH HORMONE THERAPY IN CHILDREN WITH IDIOPATHIC SHORT STATURE
• Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
• Effect of growth hormone treatment on children with idiopathic short stature (ISS), idiopathic growth hormone deficiency (IGHD), small for gestational age (SGA) and Turner syndrome (TS) in a tertiary care center

B-B-But ISS Children Grew Taller why can’t i?

Let’s clarify: ISS children are not short simply because of genetics. ISS is defined as short stature without a known cause, that INCLUDES GENETICS and many children diagnosed as having ISS have partial GH insensitivity (Evidence: Idiopathic short stature)

Bottom line: if you are within normal growth ranges and are not diagnosed as ISS, these studies do NOT apply to you.

3. Why HGH does NOT work for healthy normal children with PROOF

Spoiler: Why HGH does NOT work for healthy normal children

For children with normal growth hormone (GH) levels, exogenous GH administration cannot increase final adult height. Here’s why:

• GH does not create new growth potential.
  The growth plates in long bones experience linear growth through their epiphyseal plates. The genetic code determines both number and proliferative capacity of chondrocytes present at these growth plates. GH promotes the growth of chondrocytes and their development into mature cells, yet it cannot boost these cells' genetic-based growth capacity beyond their existing limits.
• GH cannot override genetic determinants of stature.
  Height is a polygenic trait which multiple genetic loci control its development. The treatment of GH-sufficient children with GH therapy does not affect their gene expression or the genetic skeletal structure which their genome contains.
• Endocrine feedback loops limit excessive growth signaling.
  The GH–IGF-1 axis is tightly regulated:
  • Elevated serum IGF-1 inhibits hypothalamic GHRH secretion and stimulates somatostatin release, reducing endogenous GH production.
  • Peripheral tissues exhibit receptor-mediated resistance to supra-physiologic GH and IGF-1 concentrations, limiting further cellular proliferation.
• Physiologic ceiling effect.
  In GH-sufficient children, endogenous GH already saturates IGF-1 production and downstream growth plate signaling. Exogenous GH cannot enhance this process; the system is operating at maximal physiological capacity. Clinical evidence and studies supports these claims: children with normal GH levels do not achieve increased adult height despite high-dose GH administration

EVIDENCE AND STUDIES ON NORMAL KIDS:

Final height after growth hormone therapy in non-growth-hormone-deficient children with short stature - PubMed

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PMC

https://www.sciencedirect.com/science/article/abs/pii/S002234769470192X

No Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment - PubMed



Analogy (for conceptual clarity): Imagine a plant with genetically fixed maximum height. Adequate water and nutrients allow it to reach its potential. Adding more water beyond what it can physiologically use does not make it grow taller; it may even disrupt normal growth processes.

Summary: GH in healthy, non-deficient children simply optimizes a process that is already at capacity. There is no latent or “hidden” height to unlock the endocrine system and growth plates are already functioning at their maximum biological limits.

4. Why people think it works!!!!!!

Spoiler: Why most people think it works!!!!!!

This is where most people get fooled and start to think it’s working.

HGH can TEMPORARILY increase growth rate (as seen in the studies). You grow faster for a period, but it does NOT increase final adult height. Your genetic height ceiling remains THE SAME. In the end you will grow the same without HGH.

5. What you actually get and are paying for: Side Effects

Spoiler: What you actually get and are paying for: Side Effects

Injecting ratpiss HGH from Chinese labs is retarded and will NOT work all you are paying for are potential risks including:

• Insulin resistance
• Increased risk of type 2 diabetes
• Fluid retention and edema
• Joint pain
• Carpal tunnel syndrome
• Hip growth plate injury
• Benign intracranial hypertension (severe headaches and vision changes)
• Abnormal IGF‑1 elevations
• Theoretical increased cancer risk due to chronic IGF‑1 stimulation

​

6. Summary

Spoiler: Summary

HGH only works in:

• Documented GH deficiency
• Select ISS cases

HGH does NOT:

• Make normal kids taller than their genetics allow
• Extend growth plates
• Increase final adult height
• Create height out of nowhere

If you do not have a diagnosed condition, you will not gain any adult height you will only get side effects.

The truth?: There is no hack around genetics. Injecting Chinese ratpiss HGH is expensive, unnecessary, and retarded.



Biology does not care about your retarded cope.

amazing post

 

[crn]

Okay let me get this right?
You want me to explain why someone with a tumor in their brain that releases HIGH DOSES OF HGH 24/7, bypasses their hypothalamic-pituitary feedback loop, is barely researched, and comes alongside other endocrine abnormalities, is the same as a normal kid injecting HGH?

Really?

@Master why are you verifying niggas like this

im not saying a healthy kid has a brain tumor, im saying the result of that tumor proves the 'senescence limit' isn't a hard biological ceiling.

if cellular senescence or genetic limits were absolute, the body would stop growing regardless of HGH levels. gigantism proves that if you saturate the receptors and keep IGF-1 high enough while plates are open, the body must continue to respond.

the feedback loop being bypassed is exactly the point exogenous HGH at high doses essentially bypasses that same loop manually. we aren't looking for 8 feet of height, we’re looking for the 1–2 inches of growth from natural final adult height.

 

[Ahmed88]

im not saying a healthy kid has a brain tumor, im saying the result of that tumor proves the 'senescence limit' isn't a hard biological ceiling.

if cellular senescence or genetic limits were absolute, the body would stop growing regardless of HGH levels. gigantism proves that if you saturate the receptors and keep IGF-1 high enough while plates are open, the body must continue to respond.

the feedback loop being bypassed is exactly the point exogenous HGH at high doses essentially bypasses that same loop manually. we aren't looking for 8 feet of height, we’re looking for the 1–2 inches of growth from natural final adult height.

Right that's the thing tho, Acromegaly a tumor state bypasses your genetic limit, you can't bypass your limit with normal HGH UNLESS YOU GIVE YOURSELF ACROMEGALY which is not possible

 

[crn]

Right that's the thing tho, Acromegaly a tumor state bypasses your genetic limit, you can't bypass your limit with normal HGH UNLESS YOU GIVE YOURSELF ACROMEGALY which is not possible

you just conceded the entire argument. by admitting that a 'tumor state' bypasses the genetic limit, you’re admitting the limit isn't a hard biological wall, it’s a hormonal threshold.

you're acting like 'acromegaly' is some magical, separate biological process. it’s not. it is literally just the physiological result of supraphysiological GH/IGF-1 levels. the bone doesn't care if the GH comes from a pituitary tumor or a needle, the receptors react to the molecule, not the source.

if you inject enough HGH to reach those same serum levels while your plates are open, you are (by definition) inducing the same growth signaling found in gigantism.

 

[Ahmed88]

it is literally just the physiological result of supraphysiological GH/IGF-1 levels

you can't bypass your limit with normal HGH UNLESS YOU GIVE YOURSELF ACROMEGALY which is not possible

Debunked yourself there mate, maybe stop using AI faggot

 

[crn]

Debunked yourself there mate, maybe stop using AI faggot

sure

you admit that the high IGF-1 from gigantism is the reason why they exceed their genetic limit, which can theoretically be replicated with high doses of HGH,


now, you wont grow to 8 feet tall (like children with gigantism) but it wouldn't be illogical to say that you wouldn't grow atleast another 1-2 inches in FAH from your baseline without exogenous HGH. (due to the high IGF-1, similar to that seen in kids with gigantism who exceeded their genetic limit)

 

[tomacōck]

Right that's the thing tho, Acromegaly a tumor state bypasses your genetic limit, you can't bypass your limit with normal HGH UNLESS YOU GIVE YOURSELF ACROMEGALY which is not possible

oh mein Gott you're so fucken stupid
@foidletslayer come JFL with me

 

[Ahmed88]

you admit that the high IGF-1 from gigantism is the reason why they exceed their genetic limit,

No, no i didn't

which can theoretically be replicated with high doses of HGH,

Acromegaly? No

but it wouldn't be illogical to say that you wouldn't grow atleast another 1-2 inches in FAH from your baseline without exogenous HGH.

It would

due to the high IGF-1

That's one of the many millions of factors yes, in acromegaly, which can not be replicated with HGH

oh mein Gott you're so fucken stupid

Why do you just leave and come back suddenly with a stupid shitty ass reply, i thought you didn't wanna debate

 

[crn]

That's one of the many millions of factors yes, in acromegaly, which can not be replicated with HGH

i don't understand your point, is it?
1) the growth plates are physically incapable of further division (even though gigantism proves they are)?
2) or that exogenous GH somehow lacks a 'secret ingredient' that tumor-driven GH has?

 

[stigmaboy]

@Ahmed88 just say no to hgh lmao cope harder bro. it won't work for u or anyone else not deficient in gh. your genetic max is ur genetic max and that's final. quit trying to make excuses for wasting money on something that will do absolutely nothing except potentially cause some weird side effects at best

 

[Ahmed88]

i don't understand your point, is it?
1) the growth plates are physically incapable of further division (even though gigantism proves they are)?
2) or that exogenous GH somehow lacks a 'secret ingredient' that tumor-driven GH has?

Neither. Gigantism is not proof that exogenous HGH injecions will increase final adult height in healthy children. It is a disease state showing what happens under chronic GH excess not a controlled/normalizable model of pharmacologic HGH use.

My original point isn’t ,,does gigantism affect growth?” but “can exogennous GH meaningfully override genetically/ developementally regulated adult height in normal physiology (without giving yourself gigantism)?” Gigantism does not answer that because it is fundamentally. different in timing duration and in a biological context. It involves continous endogenous GH hypersecretion from early development, abnormal pituitary feedback regulation, broader pituitary dysfunction etc. HGH injections are intermitent and controlled and operate within an otherwise intach endocrine system.



HGH injections also do not replicate the amounts, continuty, or features seen in gigantism. etc.



Even if you somehow managed to perfectly replicate gigantism and inject the same supraphysiologial ammounts of HGH it wouldn’t count as “normal HGH injections” but as gigantism. If you think giving yourself a couple cm for gigantism is fine then you’re welcome to try and give it to yourself. But you're going to look like a ogre before any height increse happens, because pathological features appear before linear growth effects and the condition causes severe systemic harm including insulin resistance organ enlargment joint degeneraton lifelong 24/7 pain and reduced life expectancy. It is a disease of dysregulated overgrowth not an optilized height increasing state.



So using gigantism as an argument for HGH is an category error.