Will 12 IUs of Human Growth Hormone cause Acromegaly? Extensive Study.

[stupid ugly loser]

So ur basically saying staying natural is equivalent to 12iu of hgh?

Why even bother injecting then

 

[Genio]

So ur basically saying staying natural is equivalent to 12iu of hgh?

Why even bother injecting then

No, When adjusting for Bio-availability; 12 IUs is ideal, since youll be 3 IUs over endogenous Production. Endogenous Production is equivalent to 9 IUs via pinning.

 

[stupid ugly loser]

No, When adjusting for Bio-availability; 12 IUs is ideal, since youll be 3 IUs over endogenous Production. Endogenous Production is equivalent to 9 IUs via pinning.

K I'm gonna up my dose to 12 IU

I'll give updates

 

[stupid ugly loser]

No, When adjusting for Bio-availability; 12 IUs is ideal, since youll be 3 IUs over endogenous Production. Endogenous Production is equivalent to 9 IUs via pinning.

Wait so basically that means ghrp mog hgh because you are already working with a baseline of 9iu if hgh and instead of shutting it down it's better to just enhance it via peptides?

 

[Genio]

Wait so basically that means ghrp mog hgh because you are already working with a baseline of 9iu if hgh and instead of shutting it down it's better to just enhance it via peptides?

You arent working with a baseline of 9 IU's, youre working with 6 IUs endogenously. 9 IUs is equivalent endogenously when pinning because a certain percentage of it isnt taken in (Depending of where u pin, Subq or IM)

Think of it like this, Youre Tanner IV producing 6 IUs naturally, If you were to hop on HGH, then 30 Percent of it for example wouldnt be taken in so u up it to 9 IUs to be around Endogenous Level. This is what we are discussing now, 12 IUs is recommended because its 3 IUs above Endogenous Production when accounting for Bio-availability via pinning.

 

[bddcoper]

my least favorite grey

top 1 iqlet on this forum

 

[Genio]

my least favorite grey

top 1 iqlet on this forum

no plzs bhai im sorry plz im vomiitinff all over za floor should i OD DNP and vommit cope everywehere and kill myeself because an iqlet cannot deduct basic dosaging

 

[scapular]

Will 12 IUs of Human Growth Hormone cause Acromegaly?

Multiple manlets on this Website will tell u that a Dosage like 10 to 15 IUs of HGH will cause Acromegaly, Few Examples pertain to;
acromegaly speedrun
Develop acromegaly
For tards that think HGH is a superpower

Now there are multiple Factors that come into play here when developing Acromegaly from Exogenous GH usage.

(If you do not wish to read all this, Then U can skip to reading only 3 Sections.)
1. Dosage of HGH
2. Elevated vs Pinning
3. Conclusion

#1. The Cycle's Duration
In multiple recorded Acromegaly cases, Acromegaly was caused through hightened GH Exposure for Years to Decades, And it mainly comes from Pituitary Adenoma's (Pituitary Gland Tumors). This is what we see in multiple Guinness World Record holder's for Height, They mainly have Pituitary Tumours causing Excessive Growth Hormone at an elevated rate, not in spikes (like what we see in Injections), And we particularly see in Patients with Acromegaly that this causes facial changes over the duration of Years to a Decade (and a Half in some cases). You would need to be pinning for years on end to even start having the facial aesthetics of Acromegaly.

View attachment 4501010View attachment 4501016

Sources that I used to deduce this:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12428067
https://pmc.ncbi.nlm.nih.gov/articles/PMC2563724
https://link.springer.com/article/10.1186/1472-6823-14-97
https://pubmed.ncbi.nlm.nih.gov/19884662

#2. The Dosage of HGH
Now this is the factor that most of these people focus on, The amount of HGH being pinned during your cycle. Now if youre like the first dude that was mentioned above, youll basically be called a retard because your disregarding the Timing of the Injection, How long the Cycle will be, and at what age the Pinning is; and will just act like 12 IUs will make u True Ogre while disregarding Science because the person informing u has under 50 posts lul

- What should be the Dosage taken at Tanner IV?
There are multiple arguments on what dosage fits Adolescents in Pubertal Stage Tanner IV, However, The People arguing for a lower dosage being Endogenous Production are conflating many thing's into one. Adolescents produce around 1.9 to 2.2 Milligrams of HGH per day, meaning 5.7 IUS to 6.6 IUs Daily. Now if we were to inject Human Growth Hormone, BIoavailability would be a big marker in deciding wether we grow or not. Assuming Injections will be Intra-Musculature, The Bio-Availability is really weak around that area (Measured around 63%), meaning if u were producing 6 IUs endogenously, youd need 9.6 IUs just to MATCH your Endogenous Production, and around 12 IUs to actually be having a benefit. Sub-Q has Better Bio-Availability, Ranging for 75 to 82%. Overall, you would need to be injecting over 9 IUs to actually make a difference in comparison to Endogenous (Natural) Production.
Studies I used to deduce this dosage:
https://pubmed.ncbi.nlm.nih.gov/14964431
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019640s104lbl.pdf
https://pubmed.ncbi.nlm.nih.gov/1730812

#3. Elevated Levels vs Pinning
Patients of Acromegaly and Cardiomegaly always have Elevated Levels of Human Growth Hormone and IGF1, Meaning no matter what, The HGH in their blood is always at a constant level, and higher than the Healthy Adult; This means that even IF their body wanted to lower the dosage, its efforts would be in vain. However, People who inject rHGH do not have continuously elevated GH levels in their bloodstream. After injection, The HGH will circulate around the blood, it peaks approximately 2–4 hours post-administration and is cleared from the blood within a few hours due to its short plasma half-life. The longer-lasting effects are mediated indirectly through IGF-1, which remains elevated well after circulating GH has declined; The only way u can get "acromegaly" via Exogenous HGH is by through Hightened IGF1 Levels which can cause mild acromegaloid features (not like the Ogre Features youre already informed about).
https://pubmed.ncbi.nlm.nih.gov/8949572

#4. Figures who are known to have injected large amounts of Growth Hormone
-Richi Piana 20 IUs ED of Serostim (Pharma) Human Growth Hormone.
Richi Piana has previously talked in multiple interviews about his previous cycles involving Growth Hormone, where he has started off with 8 IU's, and went up to 20 Ius daily, presumably for a few years. And he does not have a large jaw, he doesnt have a prominent nose, and he does not have Acromegaly.

-Ronnie Coleman; 9 IUs ED of Serostim.
Ronnie Coleman has talked about his experience with anabolics, while denying the use of Trenbolone, Synthol, and Insulin, admitted to using Testosterone and Human Growth Hormone under the supervision of a Doctor.

Conclusion:
No, Youre not gonna get Acromegaly if u pin HGH over 3 IUs, Your heart is not gonna buss when u decide to hop on a 3 week cycle of 6 IUs, and you aren't cutting your life span by 20 years if you go over 8 IU's. If you want to pin under 12 IUs then go for it, your money, not mine. But the entire propoganda behind "Over 10 IUs = Acromegaly, Heart attack, Cancer, and your family dying in a car crash" is frankly retarded.

Acromegaly is simply Elevated HGH Circulating in your blood for Years on end, Nobody here is going to be injecting 30 IUs of HGH for a decade. Hence Acromegaly isn't an issue to be concerned with when cycling/stacking Human Growth Hormone.

dr bookmarked

 

[Zagro]

stop making posts like this, these kids are afraid of a nonexistent side effect, let natural selection take its course. lower competition ts. also 2-3ius gh is the average amount, you sound like a retard.

No bro you get big organs and acromegaly on rhGH you’re just suicidal and crazy cause 2-3 units is too high 1-2 units 3 weeks on 6 weeks off

 

[Zagro]

You arent working with a baseline of 9 IU's, youre working with 6 IUs endogenously. 9 IUs is equivalent endogenously when pinning because a certain percentage of it isnt taken in (Depending of where u pin, Subq or IM)

Think of it like this, Youre Tanner IV producing 6 IUs naturally, If you were to hop on HGH, then 30 Percent of it for example wouldnt be taken in so u up it to 9 IUs to be around Endogenous Level. This is what we are discussing now, 12 IUs is recommended because its 3 IUs above Endogenous Production when accounting for Bio-availability via pinning.

6 ius pulsatile vs. 6 ius continuous hm

 

[lueymogs]

Will 12 IUs of Human Growth Hormone cause Acromegaly?

Multiple manlets on this Website will tell u that a Dosage like 10 to 15 IUs of HGH will cause Acromegaly, Few Examples pertain to;
acromegaly speedrun
Develop acromegaly
For tards that think HGH is a superpower

Now there are multiple Factors that come into play here when developing Acromegaly from Exogenous GH usage.

(If you do not wish to read all this, Then U can skip to reading only 3 Sections.)
1. Dosage of HGH
2. Elevated vs Pinning
3. Conclusion

#1. The Cycle's Duration
In multiple recorded Acromegaly cases, Acromegaly was caused through hightened GH Exposure for Years to Decades, And it mainly comes from Pituitary Adenoma's (Pituitary Gland Tumors). This is what we see in multiple Guinness World Record holder's for Height, They mainly have Pituitary Tumours causing Excessive Growth Hormone at an elevated rate, not in spikes (like what we see in Injections), And we particularly see in Patients with Acromegaly that this causes facial changes over the duration of Years to a Decade (and a Half in some cases). You would need to be pinning for years on end to even start having the facial aesthetics of Acromegaly.

View attachment 4501010View attachment 4501016

Sources that I used to deduce this:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12428067
https://pmc.ncbi.nlm.nih.gov/articles/PMC2563724
https://link.springer.com/article/10.1186/1472-6823-14-97
https://pubmed.ncbi.nlm.nih.gov/19884662

#2. The Dosage of HGH
Now this is the factor that most of these people focus on, The amount of HGH being pinned during your cycle. Now if youre like the first dude that was mentioned above, youll basically be called a retard because your disregarding the Timing of the Injection, How long the Cycle will be, and at what age the Pinning is; and will just act like 12 IUs will make u True Ogre while disregarding Science because the person informing u has under 50 posts lul

- What should be the Dosage taken at Tanner IV?
There are multiple arguments on what dosage fits Adolescents in Pubertal Stage Tanner IV, However, The People arguing for a lower dosage being Endogenous Production are conflating many thing's into one. Adolescents produce around 1.9 to 2.2 Milligrams of HGH per day, meaning 5.7 IUS to 6.6 IUs Daily. Now if we were to inject Human Growth Hormone, BIoavailability would be a big marker in deciding wether we grow or not. Assuming Injections will be Intra-Musculature, The Bio-Availability is really weak around that area (Measured around 63%), meaning if u were producing 6 IUs endogenously, youd need 9.6 IUs just to MATCH your Endogenous Production, and around 12 IUs to actually be having a benefit. Sub-Q has Better Bio-Availability, Ranging for 75 to 82%. Overall, you would need to be injecting over 9 IUs to actually make a difference in comparison to Endogenous (Natural) Production.
Studies I used to deduce this dosage:
https://pubmed.ncbi.nlm.nih.gov/14964431
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019640s104lbl.pdf
https://pubmed.ncbi.nlm.nih.gov/1730812

#3. Elevated Levels vs Pinning
Patients of Acromegaly and Cardiomegaly always have Elevated Levels of Human Growth Hormone and IGF1, Meaning no matter what, The HGH in their blood is always at a constant level, and higher than the Healthy Adult; This means that even IF their body wanted to lower the dosage, its efforts would be in vain. However, People who inject rHGH do not have continuously elevated GH levels in their bloodstream. After injection, The HGH will circulate around the blood, it peaks approximately 2–4 hours post-administration and is cleared from the blood within a few hours due to its short plasma half-life. The longer-lasting effects are mediated indirectly through IGF-1, which remains elevated well after circulating GH has declined; The only way u can get "acromegaly" via Exogenous HGH is by through Hightened IGF1 Levels which can cause mild acromegaloid features (not like the Ogre Features youre already informed about).
https://pubmed.ncbi.nlm.nih.gov/8949572

#4. Figures who are known to have injected large amounts of Growth Hormone
-Richi Piana 20 IUs ED of Serostim (Pharma) Human Growth Hormone.
Richi Piana has previously talked in multiple interviews about his previous cycles involving Growth Hormone, where he has started off with 8 IU's, and went up to 20 Ius daily, presumably for a few years. And he does not have a large jaw, he doesnt have a prominent nose, and he does not have Acromegaly.

-Ronnie Coleman; 9 IUs ED of Serostim.
Ronnie Coleman has talked about his experience with anabolics, while denying the use of Trenbolone, Synthol, and Insulin, admitted to using Testosterone and Human Growth Hormone under the supervision of a Doctor.

Conclusion:
No, Youre not gonna get Acromegaly if u pin HGH over 3 IUs, Your heart is not gonna buss when u decide to hop on a 3 week cycle of 6 IUs, and you aren't cutting your life span by 20 years if you go over 8 IU's. If you want to pin under 12 IUs then go for it, your money, not mine. But the entire propoganda behind "Over 10 IUs = Acromegaly, Heart attack, Cancer, and your family dying in a car crash" is frankly retarded.

Acromegaly is simply Elevated HGH Circulating in your blood for Years on end, Nobody here is going to be injecting 30 IUs of HGH for a decade. Hence Acromegaly isn't an issue to be concerned with when cycling/stacking Human Growth Hormone.

Idk

 

[introvertedextrover]

dnr attention span cooked

 

[fazehamster]

Will 12 IUs of Human Growth Hormone cause Acromegaly?

Multiple manlets on this Website will tell u that a Dosage like 10 to 15 IUs of HGH will cause Acromegaly, Few Examples pertain to;
acromegaly speedrun
Develop acromegaly
For tards that think HGH is a superpower

Now there are multiple Factors that come into play here when developing Acromegaly from Exogenous GH usage.

(If you do not wish to read all this, Then U can skip to reading only 3 Sections.)
1. Dosage of HGH
2. Elevated vs Pinning
3. Conclusion

#1. The Cycle's Duration
In multiple recorded Acromegaly cases, Acromegaly was caused through hightened GH Exposure for Years to Decades, And it mainly comes from Pituitary Adenoma's (Pituitary Gland Tumors). This is what we see in multiple Guinness World Record holder's for Height, They mainly have Pituitary Tumours causing Excessive Growth Hormone at an elevated rate, not in spikes (like what we see in Injections), And we particularly see in Patients with Acromegaly that this causes facial changes over the duration of Years to a Decade (and a Half in some cases). You would need to be pinning for years on end to even start having the facial aesthetics of Acromegaly.

View attachment 4501010View attachment 4501016

Sources that I used to deduce this:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12428067
https://pmc.ncbi.nlm.nih.gov/articles/PMC2563724
https://link.springer.com/article/10.1186/1472-6823-14-97
https://pubmed.ncbi.nlm.nih.gov/19884662

#2. The Dosage of HGH
Now this is the factor that most of these people focus on, The amount of HGH being pinned during your cycle. Now if youre like the first dude that was mentioned above, youll basically be called a retard because your disregarding the Timing of the Injection, How long the Cycle will be, and at what age the Pinning is; and will just act like 12 IUs will make u True Ogre while disregarding Science because the person informing u has under 50 posts lul

- What should be the Dosage taken at Tanner IV?
There are multiple arguments on what dosage fits Adolescents in Pubertal Stage Tanner IV, However, The People arguing for a lower dosage being Endogenous Production are conflating many thing's into one. Adolescents produce around 1.9 to 2.2 Milligrams of HGH per day, meaning 5.7 IUS to 6.6 IUs Daily. Now if we were to inject Human Growth Hormone, BIoavailability would be a big marker in deciding wether we grow or not. Assuming Injections will be Intra-Musculature, The Bio-Availability is really weak around that area (Measured around 63%), meaning if u were producing 6 IUs endogenously, youd need 9.6 IUs just to MATCH your Endogenous Production, and around 12 IUs to actually be having a benefit. Sub-Q has Better Bio-Availability, Ranging for 75 to 82%. Overall, you would need to be injecting over 9 IUs to actually make a difference in comparison to Endogenous (Natural) Production.
Studies I used to deduce this dosage:
https://pubmed.ncbi.nlm.nih.gov/14964431
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019640s104lbl.pdf
https://pubmed.ncbi.nlm.nih.gov/1730812

#3. Elevated Levels vs Pinning
Patients of Acromegaly and Cardiomegaly always have Elevated Levels of Human Growth Hormone and IGF1, Meaning no matter what, The HGH in their blood is always at a constant level, and higher than the Healthy Adult; This means that even IF their body wanted to lower the dosage, its efforts would be in vain. However, People who inject rHGH do not have continuously elevated GH levels in their bloodstream. After injection, The HGH will circulate around the blood, it peaks approximately 2–4 hours post-administration and is cleared from the blood within a few hours due to its short plasma half-life. The longer-lasting effects are mediated indirectly through IGF-1, which remains elevated well after circulating GH has declined; The only way u can get "acromegaly" via Exogenous HGH is by through Hightened IGF1 Levels which can cause mild acromegaloid features (not like the Ogre Features youre already informed about).
https://pubmed.ncbi.nlm.nih.gov/8949572

#4. Figures who are known to have injected large amounts of Growth Hormone
-Richi Piana 20 IUs ED of Serostim (Pharma) Human Growth Hormone.
Richi Piana has previously talked in multiple interviews about his previous cycles involving Growth Hormone, where he has started off with 8 IU's, and went up to 20 Ius daily, presumably for a few years. And he does not have a large jaw, he doesnt have a prominent nose, and he does not have Acromegaly.

-Ronnie Coleman; 9 IUs ED of Serostim.
Ronnie Coleman has talked about his experience with anabolics, while denying the use of Trenbolone, Synthol, and Insulin, admitted to using Testosterone and Human Growth Hormone under the supervision of a Doctor.

Conclusion:
No, Youre not gonna get Acromegaly if u pin HGH over 3 IUs, Your heart is not gonna buss when u decide to hop on a 3 week cycle of 6 IUs, and you aren't cutting your life span by 20 years if you go over 8 IU's. If you want to pin under 12 IUs then go for it, your money, not mine. But the entire propoganda behind "Over 10 IUs = Acromegaly, Heart attack, Cancer, and your family dying in a car crash" is frankly retarded.

Acromegaly is simply Elevated HGH Circulating in your blood for Years on end, Nobody here is going to be injecting 30 IUs of HGH for a decade. Hence Acromegaly isn't an issue to be concerned with when cycling/stacking Human Growth Hormone.

High iq thread

 

[Genio]

High iq thread

Have a few other threads otw, I just need to focus on my Studies first then ill get to writing them, thanks for the rep pookielooks

 

[fazehamster]

Have a few other threads otw, I just need to focus on my Studies first then ill get to writing them, thanks for the rep pookielooks

No bhai I’ll always rep u

 

[observador]

Whats your hgh source?

are you retarded? i said 2-3ius is the average amount for gh therapy because thats the natural average amount for kids in puberty. thats why its called gh replacement not supraphysiologic gh therapy. also my 20ius from gh and secretagogues barely costs me $150 a month. i spend more on salmon monthly. you sound like a retard whos trying to sound like he has an ounce of a unique opinion/discovery

 

[chot]

Whats your hgh source?

I gotchu for $20

 

[justheretohelppl]

Not yet, but soon I will be. Just need my stack to stop getting hoarded at customs like the past 3 times

curious on how it will go.
is low dosing better than nothing?

 

[Genio]

curious on how it will go.
is low dosing better than nothing?

imo not really, Stronger effect than endogenous, sure, but its not the same amount as endogenous, essentially just missing out on height purposefully.

 

[justheretohelppl]

imo not really, Stronger effect than endogenous, sure, but its not the same amount as endogenous, essentially just missing out on height purposefully.

right, but if someone's choice is between not pinning, and low dosing (basically anybody who gets gh from doctors only has these options), you'd say low dosing would be better than nothing correct?

 

[Genio]

right, but if someone's choice is between not pinning, and low dosing (basically anybody who gets gh from doctors only has these options), you'd say low dosing would be better than nothing correct?

Well if u got GH from the doctors, then your GH deficient, obviously it would be a better choice, and the 12 IUs system wouldnt apply to u. This post is for those with healthy Endogenous Production interested in exceeding it exogenously.

 

[raffersimmonsr]

I’d be homeless if I bought enough to pin 12iu ed

 

[infrainfra]

Will 12 IUs of Human Growth Hormone cause Acromegaly?

Multiple manlets on this Website will tell u that a Dosage like 10 to 15 IUs of HGH will cause Acromegaly, Few Examples pertain to;
acromegaly speedrun
Develop acromegaly
For tards that think HGH is a superpower

Now there are multiple Factors that come into play here when developing Acromegaly from Exogenous GH usage.

(If you do not wish to read all this, Then U can skip to reading only 3 Sections.)
1. Dosage of HGH
2. Elevated vs Pinning
3. Conclusion

#1. The Cycle's Duration
In multiple recorded Acromegaly cases, Acromegaly was caused through hightened GH Exposure for Years to Decades, And it mainly comes from Pituitary Adenoma's (Pituitary Gland Tumors). This is what we see in multiple Guinness World Record holder's for Height, They mainly have Pituitary Tumours causing Excessive Growth Hormone at an elevated rate, not in spikes (like what we see in Injections), And we particularly see in Patients with Acromegaly that this causes facial changes over the duration of Years to a Decade (and a Half in some cases). You would need to be pinning for years on end to even start having the facial aesthetics of Acromegaly.

View attachment 4501010View attachment 4501016

Sources that I used to deduce this:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12428067
https://pmc.ncbi.nlm.nih.gov/articles/PMC2563724
https://link.springer.com/article/10.1186/1472-6823-14-97
https://pubmed.ncbi.nlm.nih.gov/19884662

#2. The Dosage of HGH
Now this is the factor that most of these people focus on, The amount of HGH being pinned during your cycle. Now if youre like the first dude that was mentioned above, youll basically be called a retard because your disregarding the Timing of the Injection, How long the Cycle will be, and at what age the Pinning is; and will just act like 12 IUs will make u True Ogre while disregarding Science because the person informing u has under 50 posts lul

- What should be the Dosage taken at Tanner IV?
There are multiple arguments on what dosage fits Adolescents in Pubertal Stage Tanner IV, However, The People arguing for a lower dosage being Endogenous Production are conflating many thing's into one. Adolescents produce around 1.9 to 2.2 Milligrams of HGH per day, meaning 5.7 IUS to 6.6 IUs Daily. Now if we were to inject Human Growth Hormone, BIoavailability would be a big marker in deciding wether we grow or not. Assuming Injections will be Intra-Musculature, The Bio-Availability is really weak around that area (Measured around 63%), meaning if u were producing 6 IUs endogenously, youd need 9.6 IUs just to MATCH your Endogenous Production, and around 12 IUs to actually be having a benefit. Sub-Q has Better Bio-Availability, Ranging for 75 to 82%. Overall, you would need to be injecting over 9 IUs to actually make a difference in comparison to Endogenous (Natural) Production.
Studies I used to deduce this dosage:
https://pubmed.ncbi.nlm.nih.gov/14964431
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019640s104lbl.pdf
https://pubmed.ncbi.nlm.nih.gov/1730812

#3. Elevated Levels vs Pinning
Patients of Acromegaly and Cardiomegaly always have Elevated Levels of Human Growth Hormone and IGF1, Meaning no matter what, The HGH in their blood is always at a constant level, and higher than the Healthy Adult; This means that even IF their body wanted to lower the dosage, its efforts would be in vain. However, People who inject rHGH do not have continuously elevated GH levels in their bloodstream. After injection, The HGH will circulate around the blood, it peaks approximately 2–4 hours post-administration and is cleared from the blood within a few hours due to its short plasma half-life. The longer-lasting effects are mediated indirectly through IGF-1, which remains elevated well after circulating GH has declined; The only way u can get "acromegaly" via Exogenous HGH is by through Hightened IGF1 Levels which can cause mild acromegaloid features (not like the Ogre Features youre already informed about).
https://pubmed.ncbi.nlm.nih.gov/8949572

#4. Figures who are known to have injected large amounts of Growth Hormone
-Richi Piana 20 IUs ED of Serostim (Pharma) Human Growth Hormone.
Richi Piana has previously talked in multiple interviews about his previous cycles involving Growth Hormone, where he has started off with 8 IU's, and went up to 20 Ius daily, presumably for a few years. And he does not have a large jaw, he doesnt have a prominent nose, and he does not have Acromegaly.

-Ronnie Coleman; 9 IUs ED of Serostim.
Ronnie Coleman has talked about his experience with anabolics, while denying the use of Trenbolone, Synthol, and Insulin, admitted to using Testosterone and Human Growth Hormone under the supervision of a Doctor.

Conclusion:
No, Youre not gonna get Acromegaly if u pin HGH over 3 IUs, Your heart is not gonna buss when u decide to hop on a 3 week cycle of 6 IUs, and you aren't cutting your life span by 20 years if you go over 8 IU's. If you want to pin under 12 IUs then go for it, your money, not mine. But the entire propoganda behind "Over 10 IUs = Acromegaly, Heart attack, Cancer, and your family dying in a car crash" is frankly retarded.

Acromegaly is simply Elevated HGH Circulating in your blood for Years on end, Nobody here is going to be injecting 30 IUs of HGH for a decade. Hence Acromegaly isn't an issue to be concerned with when cycling/stacking Human Growth Hormone.

so whats optimal dose for 65kg? for instance

 

[zurrity]

Will 12 IUs of Human Growth Hormone cause Acromegaly?

Multiple manlets on this Website will tell u that a Dosage like 10 to 15 IUs of HGH will cause Acromegaly, Few Examples pertain to;
acromegaly speedrun
Develop acromegaly
For tards that think HGH is a superpower

Now there are multiple Factors that come into play here when developing Acromegaly from Exogenous GH usage.

(If you do not wish to read all this, Then U can skip to reading only 3 Sections.)
1. Dosage of HGH
2. Elevated vs Pinning
3. Conclusion

#1. The Cycle's Duration
In multiple recorded Acromegaly cases, Acromegaly was caused through hightened GH Exposure for Years to Decades, And it mainly comes from Pituitary Adenoma's (Pituitary Gland Tumors). This is what we see in multiple Guinness World Record holder's for Height, They mainly have Pituitary Tumours causing Excessive Growth Hormone at an elevated rate, not in spikes (like what we see in Injections), And we particularly see in Patients with Acromegaly that this causes facial changes over the duration of Years to a Decade (and a Half in some cases). You would need to be pinning for years on end to even start having the facial aesthetics of Acromegaly.

View attachment 4501010View attachment 4501016

Sources that I used to deduce this:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12428067
https://pmc.ncbi.nlm.nih.gov/articles/PMC2563724
https://link.springer.com/article/10.1186/1472-6823-14-97
https://pubmed.ncbi.nlm.nih.gov/19884662

#2. The Dosage of HGH
Now this is the factor that most of these people focus on, The amount of HGH being pinned during your cycle. Now if youre like the first dude that was mentioned above, youll basically be called a retard because your disregarding the Timing of the Injection, How long the Cycle will be, and at what age the Pinning is; and will just act like 12 IUs will make u True Ogre while disregarding Science because the person informing u has under 50 posts lul

- What should be the Dosage taken at Tanner IV?
There are multiple arguments on what dosage fits Adolescents in Pubertal Stage Tanner IV, However, The People arguing for a lower dosage being Endogenous Production are conflating many thing's into one. Adolescents produce around 1.9 to 2.2 Milligrams of HGH per day, meaning 5.7 IUS to 6.6 IUs Daily. Now if we were to inject Human Growth Hormone, BIoavailability would be a big marker in deciding wether we grow or not. Assuming Injections will be Intra-Musculature, The Bio-Availability is really weak around that area (Measured around 63%), meaning if u were producing 6 IUs endogenously, youd need 9.6 IUs just to MATCH your Endogenous Production, and around 12 IUs to actually be having a benefit. Sub-Q has Better Bio-Availability, Ranging for 75 to 82%. Overall, you would need to be injecting over 9 IUs to actually make a difference in comparison to Endogenous (Natural) Production.
Studies I used to deduce this dosage:
https://pubmed.ncbi.nlm.nih.gov/14964431
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019640s104lbl.pdf
https://pubmed.ncbi.nlm.nih.gov/1730812

#3. Elevated Levels vs Pinning
Patients of Acromegaly and Cardiomegaly always have Elevated Levels of Human Growth Hormone and IGF1, Meaning no matter what, The HGH in their blood is always at a constant level, and higher than the Healthy Adult; This means that even IF their body wanted to lower the dosage, its efforts would be in vain. However, People who inject rHGH do not have continuously elevated GH levels in their bloodstream. After injection, The HGH will circulate around the blood, it peaks approximately 2–4 hours post-administration and is cleared from the blood within a few hours due to its short plasma half-life. The longer-lasting effects are mediated indirectly through IGF-1, which remains elevated well after circulating GH has declined; The only way u can get "acromegaly" via Exogenous HGH is by through Hightened IGF1 Levels which can cause mild acromegaloid features (not like the Ogre Features youre already informed about).
https://pubmed.ncbi.nlm.nih.gov/8949572

#4. Figures who are known to have injected large amounts of Growth Hormone
-Richi Piana 20 IUs ED of Serostim (Pharma) Human Growth Hormone.
Richi Piana has previously talked in multiple interviews about his previous cycles involving Growth Hormone, where he has started off with 8 IU's, and went up to 20 Ius daily, presumably for a few years. And he does not have a large jaw, he doesnt have a prominent nose, and he does not have Acromegaly.

-Ronnie Coleman; 9 IUs ED of Serostim.
Ronnie Coleman has talked about his experience with anabolics, while denying the use of Trenbolone, Synthol, and Insulin, admitted to using Testosterone and Human Growth Hormone under the supervision of a Doctor.

Conclusion:
No, Youre not gonna get Acromegaly if u pin HGH over 3 IUs, Your heart is not gonna buss when u decide to hop on a 3 week cycle of 6 IUs, and you aren't cutting your life span by 20 years if you go over 8 IU's. If you want to pin under 12 IUs then go for it, your money, not mine. But the entire propoganda behind "Over 10 IUs = Acromegaly, Heart attack, Cancer, and your family dying in a car crash" is frankly retarded.

Acromegaly is simply Elevated HGH Circulating in your blood for Years on end, Nobody here is going to be injecting 30 IUs of HGH for a decade. Hence Acromegaly isn't an issue to be concerned with when cycling/stacking Human Growth Hormone.

Will 12 IUs of Human Growth Hormone cause Acromegaly?

Multiple manlets on this Website will tell u that a Dosage like 10 to 15 IUs of HGH will cause Acromegaly, Few Examples pertain to;
acromegaly speedrun
Develop acromegaly
For tards that think HGH is a superpower

Now there are multiple Factors that come into play here when developing Acromegaly from Exogenous GH usage.

(If you do not wish to read all this, Then U can skip to reading only 3 Sections.)
1. Dosage of HGH
2. Elevated vs Pinning
3. Conclusion

#1. The Cycle's Duration
In multiple recorded Acromegaly cases, Acromegaly was caused through hightened GH Exposure for Years to Decades, And it mainly comes from Pituitary Adenoma's (Pituitary Gland Tumors). This is what we see in multiple Guinness World Record holder's for Height, They mainly have Pituitary Tumours causing Excessive Growth Hormone at an elevated rate, not in spikes (like what we see in Injections), And we particularly see in Patients with Acromegaly that this causes facial changes over the duration of Years to a Decade (and a Half in some cases). You would need to be pinning for years on end to even start having the facial aesthetics of Acromegaly.

View attachment 4501010View attachment 4501016

Sources that I used to deduce this:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12428067
https://pmc.ncbi.nlm.nih.gov/articles/PMC2563724
https://link.springer.com/article/10.1186/1472-6823-14-97
https://pubmed.ncbi.nlm.nih.gov/19884662

#2. The Dosage of HGH
Now this is the factor that most of these people focus on, The amount of HGH being pinned during your cycle. Now if youre like the first dude that was mentioned above, youll basically be called a retard because your disregarding the Timing of the Injection, How long the Cycle will be, and at what age the Pinning is; and will just act like 12 IUs will make u True Ogre while disregarding Science because the person informing u has under 50 posts lul

- What should be the Dosage taken at Tanner IV?
There are multiple arguments on what dosage fits Adolescents in Pubertal Stage Tanner IV, However, The People arguing for a lower dosage being Endogenous Production are conflating many thing's into one. Adolescents produce around 1.9 to 2.2 Milligrams of HGH per day, meaning 5.7 IUS to 6.6 IUs Daily. Now if we were to inject Human Growth Hormone, BIoavailability would be a big marker in deciding wether we grow or not. Assuming Injections will be Intra-Musculature, The Bio-Availability is really weak around that area (Measured around 63%), meaning if u were producing 6 IUs endogenously, youd need 9.6 IUs just to MATCH your Endogenous Production, and around 12 IUs to actually be having a benefit. Sub-Q has Better Bio-Availability, Ranging for 75 to 82%. Overall, you would need to be injecting over 9 IUs to actually make a difference in comparison to Endogenous (Natural) Production.
Studies I used to deduce this dosage:
https://pubmed.ncbi.nlm.nih.gov/14964431
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019640s104lbl.pdf
https://pubmed.ncbi.nlm.nih.gov/1730812

#3. Elevated Levels vs Pinning
Patients of Acromegaly and Cardiomegaly always have Elevated Levels of Human Growth Hormone and IGF1, Meaning no matter what, The HGH in their blood is always at a constant level, and higher than the Healthy Adult; This means that even IF their body wanted to lower the dosage, its efforts would be in vain. However, People who inject rHGH do not have continuously elevated GH levels in their bloodstream. After injection, The HGH will circulate around the blood, it peaks approximately 2–4 hours post-administration and is cleared from the blood within a few hours due to its short plasma half-life. The longer-lasting effects are mediated indirectly through IGF-1, which remains elevated well after circulating GH has declined; The only way u can get "acromegaly" via Exogenous HGH is by through Hightened IGF1 Levels which can cause mild acromegaloid features (not like the Ogre Features youre already informed about).
https://pubmed.ncbi.nlm.nih.gov/8949572

#4. Figures who are known to have injected large amounts of Growth Hormone
-Richi Piana 20 IUs ED of Serostim (Pharma) Human Growth Hormone.
Richi Piana has previously talked in multiple interviews about his previous cycles involving Growth Hormone, where he has started off with 8 IU's, and went up to 20 Ius daily, presumably for a few years. And he does not have a large jaw, he doesnt have a prominent nose, and he does not have Acromegaly.

-Ronnie Coleman; 9 IUs ED of Serostim.
Ronnie Coleman has talked about his experience with anabolics, while denying the use of Trenbolone, Synthol, and Insulin, admitted to using Testosterone and Human Growth Hormone under the supervision of a Doctor.

Conclusion:
No, Youre not gonna get Acromegaly if u pin HGH over 3 IUs, Your heart is not gonna buss when u decide to hop on a 3 week cycle of 6 IUs, and you aren't cutting your life span by 20 years if you go over 8 IU's. If you want to pin under 12 IUs then go for it, your money, not mine. But the entire propoganda behind "Over 10 IUs = Acromegaly, Heart attack, Cancer, and your family dying in a car crash" is frankly retarded.

Acromegaly is simply Elevated HGH Circulating in your blood for Years on end, Nobody here is going to be injecting 30 IUs of HGH for a decade. Hence Acromegaly isn't an issue to be concerned with when cycling/stacking Human Growth Hormone.

Why would i need 9ius just to match my production. Why do i need to match my production. Are you saying I have to inject more than I produce instead of letting it stack together? (if that makes sense)

 

[HubertSkeletrix]

well, when trying to grow new bones with GH
what are you causing to grow them?

 

[Genio]

Why would i need 9ius just to match my production. Why do i need to match my production. Are you saying I have to inject more than I produce instead of letting it stack together? (if that makes sense)

It doesnt stack together, Exogenous Hormones shut down natural production via negative feedback causing your production to be zero.

you need to match production so that u dont stunt your growth more than it already is.