Will test with an AI close growth plates at 16?

[Pasha33]

Just some extra points.
I hit puberty pretty late, about 15 and i’m 16 now. I’m pretty sure my plates are still open.
Thinking of running 300mg test with an aromatase inhibitor, however will this close my plates. Is there anything better i could do?

 

[KellSS]

It's up to 16-19 years old, why are you worrying?

 

[Pasha33]

It's up to 16-19 years old, why are you worrying?

You mean plates are open til 19 max? I’m worrying because i dont want to destroy my development. I’m still pretty small so if i can grow more then i would want to

 

[Pasha33]

Just some extra points.
I hit puberty pretty late, about 15 and i’m 16 now. I’m pretty sure my plates are still open.
Thinking of running 300mg test with an aromatase inhibitor, however will this close my plates. Is there anything better i could do?

Bump

 

[David186]

As long as your blocking estrogen, you'll be fine since estrogen is what mainly causes growth plate fusion but test can also speed up bone maturity through androgen receptors but androgens play like 20-30% in growth plate closure

 

[Jesus_ist_König]

ai will keep them open for longer????

 

[Pasha33]

As long as your blocking estrogen, you'll be fine since estrogen is what mainly causes growth plate fusion but test can also speed up bone maturity through androgen receptors but androgens play like 20-30% in growth plate closure

So if i use an AI i’ll be good?

 

[Pasha33]

ai will keep them open for longer????

Yes, but if i’m using testosterone too it can do the opposite

 

[King.epstein]

Just some extra points.
I hit puberty pretty late, about 15 and i’m 16 now. I’m pretty sure my plates are still open.
Thinking of running 300mg test with an aromatase inhibitor, however will this close my plates. Is there anything better i could do?

dont use an AI, test alone doesnt close the growth plates

 

[Pasha33]

dont use an AI, test alone doesnt close the growth plates

Aromatisation from testosterone does though

 

[hardstucklmtn]

Just use aromatise inhibitor

Just some extra points.
I hit puberty pretty late, about 15 and i’m 16 now. I’m pretty sure my plates are still open.
Thinking of running 300mg test with an aromatase inhibitor, however will this close my plates. Is there anything better i could do?

 

[dragomog]

be careful with AI's if u fuck up your estrogen that's bad too

 

[Pasha33]

Just use aromatise inhibitor

did you read the post

 

[Pasha33]

be careful with AI's if u fuck up your estrogen that's bad too

How can i avoid messing up estrogen.

 

[hardstucklmtn]

Fuck my bad

did you read the post

 

[dragomog]

How can i avoid messing up estrogen.

haven't figured out yet, imma hop on 300 test too and tryna find out more about how to use ai correctly or if not to use it at all

 

[Pasha33]

haven't figured out yet, imma hop on 300 test too and tryna find out more about how to use ai correctly or if not to use it at all

bro the only reason i’m worried about closing plates is cause im 5’8 and kinda wanna grow lol

 

[Micrognathic]

TLDR: NO

Any androgenic compound will accelerate closure, though to a relatively lesser extent to that of E2.

it ages bones via the local AR signalling basically chondrocytes go from the proliferative state to the hypertrophic state quicker meaning instead of more bone growth you would get via the proliferation you mature the chondrocytes quicker and they just wait for a surge in estrogen to go in apoptosis, this is why estrogen is the main driver of epiphyseal plate ossification as it does the final strike to fully kill the chondrocytes meaning the possible bone growth, AR signalling just pushes it closer to closure but never actually closes the plates. Take a non-steroidal aromatase inhibitor if you want to minimise the androgenic load

 

[tokaeyyer]

TLDR: NO

Any androgenic compound will accelerate closure, though to a relatively lesser extent to that of E2.

it ages bones via the local AR signalling basically chondrocytes go from the proliferative state to the hypertrophic state quicker meaning instead of more bone growth you would get via the proliferation you mature the chondrocytes quicker and they just wait for a surge in estrogen to go in apoptosis, this is why estrogen is the main driver of epiphyseal plate ossification as it does the final strike to fully kill the chondrocytes meaning the possible bone growth, AR signalling just pushes it closer to closure but never actually closes the plates. Take a non-steroidal aromatase inhibitor if you want to minimise the androgenic load

what ai do you recommend?

 

[Micrognathic]

what ai do you recommend?

Any non-steroidal i.e., anastrazole or letrozole.

 

[Pasha33]

TLDR: NO

Any androgenic compound will accelerate closure, though to a relatively lesser extent to that of E2.

it ages bones via the local AR signalling basically chondrocytes go from the proliferative state to the hypertrophic state quicker meaning instead of more bone growth you would get via the proliferation you mature the chondrocytes quicker and they just wait for a surge in estrogen to go in apoptosis, this is why estrogen is the main driver of epiphyseal plate ossification as it does the final strike to fully kill the chondrocytes meaning the possible bone growth, AR signalling just pushes it closer to closure but never actually closes the plates. Take a non-steroidal aromatase inhibitor if you want to minimise the androgenic load

Any non-steroidal i.e., anastrazole or letrozole.

what about arimidex

 

[Micrognathic]

what about arimidex

Any non-steroidal i.e., anastrazole or letrozole.

 

[thuuk]

Just some extra points.
I hit puberty pretty late, about 15 and i’m 16 now. I’m pretty sure my plates are still open.
Thinking of running 300mg test with an aromatase inhibitor, however will this close my plates. Is there anything better i could do?

I mean if you monitor your e2 and not get into single digits because youre taking a way too high / way too low dose of your ai, you should be fine. Look into things like FOXO4-DRI or fgfr3 inhibitors like infi or fexa and maybe take those if youre really scared of them closing. But why not add hgh into your stack? Great combination with your test