Accutane Is Overrated, HERE'S WHY. (SKINCELS GTFIH)

[Kojo]

Accutane SERIOUSLY is overrated.

"Now why are you saying this Kojo, aren't you THE Accutane enthusiast??"

YES, I am, but it's so misused and coped about because of retards filling this forum and social media with tiktok info from a jester named CLAVICULAR.

Spoiler: My Reasoning.

This idea that you should just "microdose accutane" for skin maintenance is so retarded and is a pseudoscience Clav has pushed out arbitrarily. Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin, which is literally what we all see and feel on our face. This alone is already why topical retinoids are better.

Studies also have shown that Topical retinoids like fucking tretinoin already beat out low dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Spoiler: Studies!

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study - PubMed

Despite being safe and effective, low-dose ISO was not superior to 0.05% RA for advanced photoaging treatment.

pubmed.ncbi.nlm.nih.gov

Spoiler: Additional Reasoning (A bit Pseudoscientific but Reasonable)

Topical retinoids being applied directly onto the skin give it the advantage of changing the SURFACE of the skin. Accutanes main mechanism of action is the atrophy of Sebaceous glands (Located in the dermal layer), but being a retinoid it also does the other things the other retinoids do at a systemic level.

This is why it's also less effective for the skin because it's a spread out effect that comes from deep within the skins layers contrary to being localised onto the skin surface.

This is also why accutane can't get rid of Post-Inflammatory-Hyperpigmentation or Post-Inflammatory-Erythema, I like to think of Accutane simply as the ACNE compound not a skin compound all in all.

Skin cell turnover rate is another factor that matters but follows the prior principle of it being systemic vs topical. It sounds like an echo chamber but it matters a lot, the retinoids practically all have the same functions with accutane being a systemic version that affects the skin more deeper. But the localised action of topicals beat accutane out for skin APPERANCE.

So Kojo, if this is all true, what do you recommend I do for my skin?

Honestly I won't really overcomplicate it, You just need to attack your skin failos. Assess and diagnose the problem, look for what fixes it.

Spoiler: Methods!

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Skin Texture/Glow/Collagen - Are mainly stimulated by skin cell turnover rate and exfoliation (removing dead skin cells from the skin) in which Topical Retinoids do for you and directly on your skin, alongside chemical exfoliants.

Pairing this with something like glycolic acid can help chemically exfoliate your face, I'd only do this once a week though to avoid over-exfoliation. But imo topical retinoids and a full accutane course will mostly do the job for glowing skin and a good skin texture. (I'm seeing results in 3 days on tazarotene 0.05%)

HOW WE WILL MAINTAIN OUR RESULTS.

Spoiler: Skin Maintenance.

Tazarotene/Tretinoin - Every single Night
Cleanser/Moisturiser - Every morning and Night (Water)
Chemical Exfoliants - Once a week (preferably glycolic acid after skin gets used to retinoid)
Sunscreen - For photoaging, Use whenever going out, especially on a sunny day

Just be hygienic in general, Drink a lot of water and change bed sheets weekly. Wash your hair too.

Keep. It. Simple.

Ngl this originally was supposed to a small discussion on why I think accutane is overrated for skin and how some people misuse it but I guess it turned into a guide-esc post..

You guys can still give some feedback and disagreements though and we can CORDIALLY talk about it under this post.

Love you guys!!

Spoiler: (Some tags)

@nwed @ICL @hate @Final Fantasy @appealisLAW @ecstazy @134applesauce456 @LEFORT17 @eyezen @iqletandrew73

 

[Escanor1]

L thread dnr accutane is the best softmaxx u can do

 

[Aloof]

 

[norwoodingmanlet]

Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin,

 

[Final Fantasy]

Ill read rn but think you can't tag more than 5 people in a post otherwise warning/ban

 

[norwoodingmanlet]

Accutane SERIOUSLY is overrated.

"Now why are you saying this Kojo, aren't you THE Accutane enthusiast??"

YES, I am, but it's so misused and coped about because of retards filling this forum and social media with tiktok info from a jester named CLAVICULAR.

Spoiler: My Reasoning.

This idea that you should just "microdose accutane" for skin maintenance is so retarded and is a pseudoscience Clav has pushed out arbitrarily. Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin, which is literally what we all see and feel on our face. This alone is already why topical retinoids are better.

Studies also have shown that Topical retinoids like fucking tretinoin already beat out low dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Spoiler: Studies!

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study - PubMed

Despite being safe and effective, low-dose ISO was not superior to 0.05% RA for advanced photoaging treatment.

pubmed.ncbi.nlm.nih.gov

Spoiler: Additional Reasoning (A bit Pseudoscientific but Reasonable)

Topical retinoids being applied directly onto the skin give it the advantage of changing the SURFACE of the skin. Accutanes main mechanism of action is the atrophy of Sebaceous glands (Located in the dermal layer), but being a retinoid it also does the other things the other retinoids do at a systemic level.

This is why it's also less effective for the skin because it's a spread out effect that comes from deep within the skins layers contrary to being localised onto the skin surface.

This is also why accutane can't get rid of Post-Inflammatory-Hyperpigmentation or Post-Inflammatory-Erythema, I like to think of Accutane simply as the ACNE compound not a skin compound all in all.

Skin cell turnover rate is another factor that matters but follows the prior principle of it being systemic vs topical. It sounds like an echo chamber but it matters a lot, the retinoids practically all have the same functions with accutane being a systemic version that affects the skin more deeper. But the localised action of topicals beat accutane out for skin APPERANCE.

So Kojo, if this is all true, what do you recommend I do for my skin?

Honestly I won't really overcomplicate it, You just need to attack your skin failos. Asses and diagnose the problem, look for what fixes it.

Spoiler: Methods!

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Skin Texture/Glow/Collagen - Are mainly stimulated by skin cell turnover rate and exfoliation (removing dead skin cells from the skin) in which Topical Retinoids do for you and directly on your skin, alongside chemical exfoliants.

Pairing this with something like glycolic acid can help chemically exfoliate your face, I'd only do this once a week though to avoid over-exfoliation. But imo topical retinoids and a full accutane course will mostly do the job for glowing skin and a good skin texture. (I'm seeing results in 3 days on tazarotene 0.05%)

HOW WE WILL MAINTAIN OUR RESULTS.

Spoiler: Skin Maintenance.

Tazarotene/Tretinoin - Every single Night
Cleanser/Moisturiser - Every morning and Night (Water)
Chemical Exfoliants - Once a week (preferably glycolic acid after skin gets used to retinoid)
Sunscreen - For photoaging, Use whenever going out, especially on a sunny day

Just be hygienic in general, Drink a lot of water and change bed sheets weekly. Wash your hair too.

Keep. It. Simple.

Ngl this originally was supposed to a small discussion on why I think accutane is overrated for skin and how some people misuse it but I guess it turned into a guide-esc post..

You guys can still give some feedback and disagreements though and we can CORDIALLY talk about it under this post.

Love you guys!!

Spoiler: (Some tags)

@nwed @ICL @hate @Final Fantasy @appealisLAW @ecstazy @134applesauce456 @LEFORT17 @eyezen @iqletandrew72

retarded thread
it alters liver enzymes, makes u sensitive to sun, chap, can cause joint pain, = adjust dose to what works for you and use support and take for 1-2 years or 6-8 on higher dosages you can microdose if you want

 

[nwed]

Accutane SERIOUSLY is overrated.

"Now why are you saying this Kojo, aren't you THE Accutane enthusiast??"

YES, I am, but it's so misused and coped about because of retards filling this forum and social media with tiktok info from a jester named CLAVICULAR.

Spoiler: My Reasoning.

This idea that you should just "microdose accutane" for skin maintenance is so retarded and is a pseudoscience Clav has pushed out arbitrarily. Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin, which is literally what we all see and feel on our face. This alone is already why topical retinoids are better.

Studies also have shown that Topical retinoids like fucking tretinoin already beat out low dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Spoiler: Studies!

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study - PubMed

Despite being safe and effective, low-dose ISO was not superior to 0.05% RA for advanced photoaging treatment.

pubmed.ncbi.nlm.nih.gov

Spoiler: Additional Reasoning (A bit Pseudoscientific but Reasonable)

Topical retinoids being applied directly onto the skin give it the advantage of changing the SURFACE of the skin. Accutanes main mechanism of action is the atrophy of Sebaceous glands (Located in the dermal layer), but being a retinoid it also does the other things the other retinoids do at a systemic level.

This is why it's also less effective for the skin because it's a spread out effect that comes from deep within the skins layers contrary to being localised onto the skin surface.

This is also why accutane can't get rid of Post-Inflammatory-Hyperpigmentation or Post-Inflammatory-Erythema, I like to think of Accutane simply as the ACNE compound not a skin compound all in all.

Skin cell turnover rate is another factor that matters but follows the prior principle of it being systemic vs topical. It sounds like an echo chamber but it matters a lot, the retinoids practically all have the same functions with accutane being a systemic version that affects the skin more deeper. But the localised action of topicals beat accutane out for skin APPERANCE.

So Kojo, if this is all true, what do you recommend I do for my skin?

Honestly I won't really overcomplicate it, You just need to attack your skin failos. Asses and diagnose the problem, look for what fixes it.

Spoiler: Methods!

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Skin Texture/Glow/Collagen - Are mainly stimulated by skin cell turnover rate and exfoliation (removing dead skin cells from the skin) in which Topical Retinoids do for you and directly on your skin, alongside chemical exfoliants.

Pairing this with something like glycolic acid can help chemically exfoliate your face, I'd only do this once a week though to avoid over-exfoliation. But imo topical retinoids and a full accutane course will mostly do the job for glowing skin and a good skin texture. (I'm seeing results in 3 days on tazarotene 0.05%)

HOW WE WILL MAINTAIN OUR RESULTS.

Spoiler: Skin Maintenance.

Tazarotene/Tretinoin - Every single Night
Cleanser/Moisturiser - Every morning and Night (Water)
Chemical Exfoliants - Once a week (preferably glycolic acid after skin gets used to retinoid)
Sunscreen - For photoaging, Use whenever going out, especially on a sunny day

Just be hygienic in general, Drink a lot of water and change bed sheets weekly. Wash your hair too.

Keep. It. Simple.

Ngl this originally was supposed to a small discussion on why I think accutane is overrated for skin and how some people misuse it but I guess it turned into a guide-esc post..

You guys can still give some feedback and disagreements though and we can CORDIALLY talk about it under this post.

Love you guys!!

Spoiler: (Some tags)

@nwed @ICL @hate @Final Fantasy @appealisLAW @ecstazy @134applesauce456 @LEFORT17 @eyezen @iqletandrew72

true

lowdose accutane is more practical tho

 

[Kojo]

L thread dnr accutane is the best softmaxx u can do

Retard alert

 

[Kojo]

Ill read rn but think you can't tag more than 5 people in a post otherwise warning/ban

Oh I see, thanks

MB MODS

 

[Kojo]

View attachment 5143289

What are you attempting to say, unless there's a comprehension issue on my end. I'm pretty tired

 

[Kojo]

retarded thread
it alters liver enzymes, makes u sensitive to sun, chap, can cause joint pain, = adjust dose to what works for you and use support and take for 1-2 years or 6-8 on higher dosages you can microdose if you want

???? You're pretty much agreeing with me lol how is the thread retarded

 

[norwoodingmanlet]

What are you attempting to say, unless there's a comprehension issue on my end. I'm pretty tired

im saying it DOES penetrate the layers you said it doesnt.

the pic shows it hardly penetrates via topical (not alot)

 

[Kojo]

true

lowdose accutane is more practical tho

Why would you say that, simply out of popping a pill?

I've never gotten any skin benefits on accutane. It made my skin a little smooth but that's it.

 

[Kojo]

View attachment 5143355
im saying it DOES penetrate the layers you said it doesnt.

the pic shows it hardly penetrates via topical (not alot)

Source?

 

[Kojo]

View attachment 5143355
im saying it DOES penetrate the layers you said it doesnt.

the pic shows it hardly penetrates via topical (not alot)

And does it do this with the same efficacy as topicals

 

[Kojo]

View attachment 5143355
im saying it DOES penetrate the layers you said it doesnt.

the pic shows it hardly penetrates via topical (not alot)

And how can topicals hardless penetrate the Stratum Corneum if it's directly applied there? lmfao

 

[norwoodingmanlet]

???? You're pretty much agreeing with me lol how is the thread retarded

LOL

you are making a thread starting over with shunning microdosing and are using 40 mg

If my points are right, why are you using a higher dosage? 40 mg? bros gonna be like "to get it over with"

joint pain = BPC + TB, and sleep an extra hour to help with joint fluid increase
chapped lips = aquaphor as well as a animal fat as needed
liver enzymes: injectable L-glutathione, IM coq10, tudca, NAC, and DNR every panel after that because it will be fine

There are fixes for every issue i listed therefore a oil nuker THE ONLY, oil nuker to go in every layer is not overrated and can be used as needed.

it is the only drug that makes miracles in skin and will always be NUMBER ONE next to prp.

 

[norwoodingmanlet]

And how can topicals hardless penetrate the Stratum Corneum if it's directly applied there? lmfao

because topical ISOtretnoin is ineffective.


???????

 

[Kojo]

LOL

you are making a thread starting over with shunning microdosing and are using 40 mg

If my points are right, why are you using a higher dosage? 40 mg? bros gonna be like "to get it over with"

joint pain = BPC + TB, and sleep an extra hour to help with joint fluid increase
chapped lips = aquaphor as well as a animal fat as needed
liver enzymes: injectable L-glutathione, IM coq10, tudca, NAC, and DNR every panel after that because it will be fine

There are fixes for every issue i listed therefore a oil nuker THE ONLY, oil nuker to go in every layer is not overrated and can be used as needed.

it is the only drug that makes miracles in skin and will always be NUMBER ONE next to prp.

You clearly don't know the point of the post, and this is why retards need to stop dnring things.

The point of the post is to say accutane alone does not get your skin from inflamed looking with hyperpigmentation and bad texture, to glass glossy and smooth on it owns. More appliances are needed.

When I said microdosing accutane sucks I'm talking about for getting good glossy skin. Your comprehension levels genuinely suck

 

[norwoodingmanlet]

You clearly don't know the point of the post, and this is why retards need to stop dnring things.

The point of the post is to say accutane alone does not get your skin from inflamed looking with hyperpigmentation and bad texture, to glass glossy and smooth on it owns. More appliances are needed.

When I said microdosing accutane sucks I'm talking about for getting good glossy skin. Your comprehension levels genuinely suck

because i dnred you off your first passage because its wrong and ur post to rep ratio is shit

how about i read it and fry u more

stand by retard

 

[Kojo]

because topical ISOtretnoin is ineffective.


???????

Getting mixed info

 

[Kojo]

because i dnred you off your first passage because its wrong and ur post to rep ratio is shit

how about i read it and fry u more

stand by retard

You're low iq, but go ahead

 

[Kojo]

because topical ISOtretnoin is ineffective.


???????

Source

 

[Niebvll]

Interesting read

 

[milkshake_addict]

 

[norwoodingmanlet]

Accutane SERIOUSLY is overrated.

"Now why are you saying this Kojo, aren't you THE Accutane enthusiast??"

YES, I am, but it's so misused and coped about because of retards filling this forum and social media with tiktok info from a jester named CLAVICULAR.

Spoiler: My Reasoning.

This idea that you should just "microdose accutane" for skin maintenance is so retarded and is a pseudoscience Clav has pushed out arbitrarily. Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin, which is literally what we all see and feel on our face. This alone is already why topical retinoids are better.

Studies also have shown that Topical retinoids like fucking tretinoin already beat out low dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Spoiler: Studies!

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study - PubMed

Despite being safe and effective, low-dose ISO was not superior to 0.05% RA for advanced photoaging treatment.

pubmed.ncbi.nlm.nih.gov

Spoiler: Additional Reasoning (A bit Pseudoscientific but Reasonable)

Topical retinoids being applied directly onto the skin give it the advantage of changing the SURFACE of the skin. Accutanes main mechanism of action is the atrophy of Sebaceous glands (Located in the dermal layer), but being a retinoid it also does the other things the other retinoids do at a systemic level.

This is why it's also less effective for the skin because it's a spread out effect that comes from deep within the skins layers contrary to being localised onto the skin surface.

This is also why accutane can't get rid of Post-Inflammatory-Hyperpigmentation or Post-Inflammatory-Erythema, I like to think of Accutane simply as the ACNE compound not a skin compound all in all.

Skin cell turnover rate is another factor that matters but follows the prior principle of it being systemic vs topical. It sounds like an echo chamber but it matters a lot, the retinoids practically all have the same functions with accutane being a systemic version that affects the skin more deeper. But the localised action of topicals beat accutane out for skin APPERANCE.

So Kojo, if this is all true, what do you recommend I do for my skin?

Honestly I won't really overcomplicate it, You just need to attack your skin failos. Assess and diagnose the problem, look for what fixes it.

Spoiler: Methods!

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Skin Texture/Glow/Collagen - Are mainly stimulated by skin cell turnover rate and exfoliation (removing dead skin cells from the skin) in which Topical Retinoids do for you and directly on your skin, alongside chemical exfoliants.

Pairing this with something like glycolic acid can help chemically exfoliate your face, I'd only do this once a week though to avoid over-exfoliation. But imo topical retinoids and a full accutane course will mostly do the job for glowing skin and a good skin texture. (I'm seeing results in 3 days on tazarotene 0.05%)

HOW WE WILL MAINTAIN OUR RESULTS.

Spoiler: Skin Maintenance.

Tazarotene/Tretinoin - Every single Night
Cleanser/Moisturiser - Every morning and Night (Water)
Chemical Exfoliants - Once a week (preferably glycolic acid after skin gets used to retinoid)
Sunscreen - For photoaging, Use whenever going out, especially on a sunny day

Just be hygienic in general, Drink a lot of water and change bed sheets weekly. Wash your hair too.

Keep. It. Simple.

Ngl this originally was supposed to a small discussion on why I think accutane is overrated for skin and how some people misuse it but I guess it turned into a guide-esc post..

You guys can still give some feedback and disagreements though and we can CORDIALLY talk about it under this post.

Love you guys!!

Spoiler: (Some tags)

@nwed @ICL @hate @Final Fantasy @appealisLAW @ecstazy @134applesauce456 @LEFORT17 @eyezen @iqletandrew73

Studies have also shown that topical retinoids like fucking tretinoin already beat out low-dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Point is retarded. Taz, tret, adapalene, and retinol are all good but have a key flaw (dosing frequency) you can only dose them so much till your barrier fades away and needs a break; hence, isotretinoin is better "but bro just let your skin get used to it!" nope LOL shit logic. "It typically takes 2 to 4 months. to get used to topical tretnoin retard by that time at the 3-month mark at high dose isotretnoin youl be near 45% done with your accutane course and youll still be at 0.5 tret. hince why u use reinoids after accutane because accutane is the only possible way to get rid of acne long term

Azelaic Acid

Do I need to go further? you are retarded if you think the average person can tolerate TAZ as well as a chemical exfoliant, azelic acid, hydro, gtfo of here and even if they do takes months and accutane will already be far past that finish line by then JFLLLL

your points suck and get outshined by simple accutane+microneedling+low dose tret after your pores actually shrink


slaughtered retard

 

[norwoodingmanlet]

Source

source? if it was effective why is there one single pubmed study when we have had the idea since iso released when you search pubmed topical isotetnoin studies

gets destoryed by other reinoids and is also made to be better tolerated hince it hardly penetrating enough like we talked over?

 

[Kojo]

Studies have also shown that topical retinoids like fucking tretinoin already beat out low-dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Point is retarded. Taz, tret, adapalene, and retinol are all good but have a key flaw (dosing frequency) you can only dose them so much till your barrier fades away and needs a break; hence, isotretinoin is better "but bro just let your skin get used to it!" nope LOL shit logic. "It typically takes 2 to 4 months. to get used to topical tretnoin retard by that time at the 3-month mark at high dose isotretnoin youl be near 45% done with your accutane course and youll still be at 0.5 tret. hince why u use reinoids after accutane because accutane is the only possible way to get rid of acne long term

Azelaic Acid

Do I need to go further? you are retarded if you think the average person can tolerate TAZ as well as a chemical exfoliant, azelic acid, hydro, gtfo of here and even if they do takes months and accutane will already be far past that finish line by then JFLLLL

your points suck and get outshined by simple accutane+microneedling+low dose tret after your pores actually shrink


slaughtered retard

?????? You didn't even slaughter anything LOL, arguing 2 different things here, try comprehension.

Reread it.

 

[Kojo]

Bruh Isotretinoin is Accutane not tretinoin.

You're not getting the point, he's saying topicals don't permeate the stratum corneum whilst isotretinoin does. He has not provided the source.

 

[Deleted member 337609]

Accutane SERIOUSLY is overrated.

"Now why are you saying this Kojo, aren't you THE Accutane enthusiast??"

YES, I am, but it's so misused and coped about because of retards filling this forum and social media with tiktok info from a jester named CLAVICULAR.

Spoiler: My Reasoning.

This idea that you should just "microdose accutane" for skin maintenance is so retarded and is a pseudoscience Clav has pushed out arbitrarily. Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin, which is literally what we all see and feel on our face. This alone is already why topical retinoids are better.

Studies also have shown that Topical retinoids like fucking tretinoin already beat out low dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Spoiler: Studies!

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study - PubMed

Despite being safe and effective, low-dose ISO was not superior to 0.05% RA for advanced photoaging treatment.

pubmed.ncbi.nlm.nih.gov

Spoiler: Additional Reasoning (A bit Pseudoscientific but Reasonable)

Topical retinoids being applied directly onto the skin give it the advantage of changing the SURFACE of the skin. Accutanes main mechanism of action is the atrophy of Sebaceous glands (Located in the dermal layer), but being a retinoid it also does the other things the other retinoids do at a systemic level.

This is why it's also less effective for the skin because it's a spread out effect that comes from deep within the skins layers contrary to being localised onto the skin surface.

This is also why accutane can't get rid of Post-Inflammatory-Hyperpigmentation or Post-Inflammatory-Erythema, I like to think of Accutane simply as the ACNE compound not a skin compound all in all.

Skin cell turnover rate is another factor that matters but follows the prior principle of it being systemic vs topical. It sounds like an echo chamber but it matters a lot, the retinoids practically all have the same functions with accutane being a systemic version that affects the skin more deeper. But the localised action of topicals beat accutane out for skin APPERANCE.

So Kojo, if this is all true, what do you recommend I do for my skin?

Honestly I won't really overcomplicate it, You just need to attack your skin failos. Assess and diagnose the problem, look for what fixes it.

Spoiler: Methods!

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Skin Texture/Glow/Collagen - Are mainly stimulated by skin cell turnover rate and exfoliation (removing dead skin cells from the skin) in which Topical Retinoids do for you and directly on your skin, alongside chemical exfoliants.

Pairing this with something like glycolic acid can help chemically exfoliate your face, I'd only do this once a week though to avoid over-exfoliation. But imo topical retinoids and a full accutane course will mostly do the job for glowing skin and a good skin texture. (I'm seeing results in 3 days on tazarotene 0.05%)

HOW WE WILL MAINTAIN OUR RESULTS.

Spoiler: Skin Maintenance.

Tazarotene/Tretinoin - Every single Night
Cleanser/Moisturiser - Every morning and Night (Water)
Chemical Exfoliants - Once a week (preferably glycolic acid after skin gets used to retinoid)
Sunscreen - For photoaging, Use whenever going out, especially on a sunny day

Just be hygienic in general, Drink a lot of water and change bed sheets weekly. Wash your hair too.

Keep. It. Simple.

Ngl this originally was supposed to a small discussion on why I think accutane is overrated for skin and how some people misuse it but I guess it turned into a guide-esc post..

You guys can still give some feedback and disagreements though and we can CORDIALLY talk about it under this post.

Love you guys!!

Spoiler: (Some tags)

@nwed @ICL @hate @Final Fantasy @appealisLAW @ecstazy @134applesauce456 @LEFORT17 @eyezen @iqletandrew73

mirin

 

[Matrix88]

thanks for this post, very useful.

I got a question, if I use Taz every night and eventually I start a course of Accutane, can I still use Taz every night since they are doing different things?

 

[Kojo]

View attachment 5143724

He clearly said topical Isotretnoin is ineffect. Thus it does not permeate it.

I thought he was referring to tretinoin as a lot of retards mean tretinoin when they say "topical isotretinoin" So that's just a misunderstanding. I didn't see the relevance of bringing up a discontinued compound when they aren't identical to the others being spoken about.

View attachment 5143803
You clearly reply to him with a unrelated tretinoin repose. This would only be relevant if you though Isotretinoin was also tretinoin.

Before you go but his prior post. Permeation and penetration are not the same thing.

Permeation for topical tretinoin is the drug delivery method. In his prior response he was talking about random left over oral isotretinoin residual being excreted, not a delivery method.

Then he still wouldn't really be making a sound point if its just "left out" residue of the drug being excreted and not actually interacting with the stratum corneum? or are you implying otherwise.

Also, him showing topical iso not making it is a false equivalence as topical iso's purpose is to act similarly to how oral iso works which is to deeply affect the skin still.

 

[Kojo]

thanks for this post, very useful.

Thank you bhai, some pseudo intellectuals here who act like they're intelligent couldn't even comprehend what the aim of this post was jfl

I got a question, if I use Taz every night and eventually I start a course of Accutane, can I still use Taz every night since they are doing different things?

Yes you can, your face will just be really really dry and peeling. But you can use both, I'm currently doing it lol just be prepared for intense burning for like 10 seconds after applying moisturiser.

Skin will get super dry throughout the day too just keep moisturising

 

[Matrix88]

Thank you bhai, some pseudo intellectuals here who act like they're intelligent couldn't even comprehend what the aim of this post was jfl

Yes you can, your face will just be really really dry and peeling. But you can use both, I'm currently doing it lol just be prepared for intense burning for like 10 seconds after applying moisturiser.

Skin will get super dry throughout the day too just keep moisturising

Ok perfect. You helped me bro, I considered switching to micro doses of accutane for my acne and I thought it would do the same as topical retinoids lol

And what do u think about the hair loss side effects of accutane? Will they affect me if I'm on dutasteride + minox?

 

[Kojo]

Ok perfect. You helped me bro, I considered switching to micro doses of accutane for my acne and I thought it would do the same as topical retinoids lol

And what do u think about the hair loss side effects of accutane? Will they affect me if I'm on dutasteride + minox?

I believe accutane gives temporary telogen effluvium through drying out the hair a lot. I think keeping your hair moisturised will help it, your minoxidil will likely help it a lot too.

Also if you have acne, use accutane. I hope the point of my thread isn't being too miscontrued by people.

The point I wanted to make is accutane is pretty much only good for solving the acne problem, it does nothing else good like Skin MAINTENANCE or fixing issues like pie/pih/bad skin texture or apperance. So if you do have persistent acne, just use the isotret brother.

But for achieving and maintaining model tier skin in general "microdosing accutane" isn't the way to go is pretty much the point in a nutshell

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Just to quote myself^

 

[Matrix88]

I hope the point of my thread isn't being too miscontrued by people.

yea yea I got your point, thanks bro

 

[Matrix88]

I believe accutane gives temporary telogen effluvium through drying out the hair a lot. I think keeping your hair moisturised will help it, your minoxidil will likely help it a lot too.

it isn't permanent right? TwT

 

[Kojo]

it isn't permanent right? TwT

lol no, telogen effluvium is just when the hairs get pushed into the resting phase faster than usual. (Because of the drying), it is completely temporary, you're fine.

Minoxidil should actually combat this as it pushes more hairs into the growth phase

 

[Matrix88]

lol no, telogen effluvium is just when the hairs get pushed into the resting phase faster than usual. (Because of the drying), it is completely temporary, you're fine.

Minoxidil should actually combat this as it pushes more hairs into the growth phase

Perfect, I read that it could be permanent due to Accutane shrinking permanently hair follicles

 

[LANCEPRETTYBOY]

Accutane SERIOUSLY is overrated.

"Now why are you saying this Kojo, aren't you THE Accutane enthusiast??"

YES, I am, but it's so misused and coped about because of retards filling this forum and social media with tiktok info from a jester named CLAVICULAR.

Spoiler: My Reasoning.

This idea that you should just "microdose accutane" for skin maintenance is so retarded and is a pseudoscience Clav has pushed out arbitrarily. Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin, which is literally what we all see and feel on our face. This alone is already why topical retinoids are better.

Studies also have shown that Topical retinoids like fucking tretinoin already beat out low dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Spoiler: Studies!

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study - PubMed

Despite being safe and effective, low-dose ISO was not superior to 0.05% RA for advanced photoaging treatment.

pubmed.ncbi.nlm.nih.gov

Spoiler: Additional Reasoning (A bit Pseudoscientific but Reasonable)

Topical retinoids being applied directly onto the skin give it the advantage of changing the SURFACE of the skin. Accutanes main mechanism of action is the atrophy of Sebaceous glands (Located in the dermal layer), but being a retinoid it also does the other things the other retinoids do at a systemic level.

This is why it's also less effective for the skin because it's a spread out effect that comes from deep within the skins layers contrary to being localised onto the skin surface.

This is also why accutane can't get rid of Post-Inflammatory-Hyperpigmentation or Post-Inflammatory-Erythema, I like to think of Accutane simply as the ACNE compound not a skin compound all in all.

Skin cell turnover rate is another factor that matters but follows the prior principle of it being systemic vs topical. It sounds like an echo chamber but it matters a lot, the retinoids practically all have the same functions with accutane being a systemic version that affects the skin more deeper. But the localised action of topicals beat accutane out for skin APPERANCE.

So Kojo, if this is all true, what do you recommend I do for my skin?

Honestly I won't really overcomplicate it, You just need to attack your skin failos. Assess and diagnose the problem, look for what fixes it.

Spoiler: Methods!

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Skin Texture/Glow/Collagen - Are mainly stimulated by skin cell turnover rate and exfoliation (removing dead skin cells from the skin) in which Topical Retinoids do for you and directly on your skin, alongside chemical exfoliants.

Pairing this with something like glycolic acid can help chemically exfoliate your face, I'd only do this once a week though to avoid over-exfoliation. But imo topical retinoids and a full accutane course will mostly do the job for glowing skin and a good skin texture. (I'm seeing results in 3 days on tazarotene 0.05%)

HOW WE WILL MAINTAIN OUR RESULTS.

Spoiler: Skin Maintenance.

Tazarotene/Tretinoin - Every single Night
Cleanser/Moisturiser - Every morning and Night (Water)
Chemical Exfoliants - Once a week (preferably glycolic acid after skin gets used to retinoid)
Sunscreen - For photoaging, Use whenever going out, especially on a sunny day

Just be hygienic in general, Drink a lot of water and change bed sheets weekly. Wash your hair too.

Keep. It. Simple.

Ngl this originally was supposed to a small discussion on why I think accutane is overrated for skin and how some people misuse it but I guess it turned into a guide-esc post..

You guys can still give some feedback and disagreements though and we can CORDIALLY talk about it under this post.

Love you guys!!

Spoiler: (Some tags)

@nwed @ICL @hate @Final Fantasy @appealisLAW @ecstazy @134applesauce456 @LEFORT17 @eyezen @iqletandrew73

do i need to exfoliate if i already use tret? can tret alone improve my texture

 

[SfPBP]

So I should stop taking low dose Accutane and just use tretinoin

 

[ayko]

Accutane SERIOUSLY is overrated.

"Now why are you saying this Kojo, aren't you THE Accutane enthusiast??"

YES, I am, but it's so misused and coped about because of retards filling this forum and social media with tiktok info from a jester named CLAVICULAR.

Spoiler: My Reasoning.

This idea that you should just "microdose accutane" for skin maintenance is so retarded and is a pseudoscience Clav has pushed out arbitrarily. Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin, which is literally what we all see and feel on our face. This alone is already why topical retinoids are better.

Studies also have shown that Topical retinoids like fucking tretinoin already beat out low dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Spoiler: Studies!

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study - PubMed

Despite being safe and effective, low-dose ISO was not superior to 0.05% RA for advanced photoaging treatment.

pubmed.ncbi.nlm.nih.gov

Spoiler: Additional Reasoning (A bit Pseudoscientific but Reasonable)

Topical retinoids being applied directly onto the skin give it the advantage of changing the SURFACE of the skin. Accutanes main mechanism of action is the atrophy of Sebaceous glands (Located in the dermal layer), but being a retinoid it also does the other things the other retinoids do at a systemic level.

This is why it's also less effective for the skin because it's a spread out effect that comes from deep within the skins layers contrary to being localised onto the skin surface.

This is also why accutane can't get rid of Post-Inflammatory-Hyperpigmentation or Post-Inflammatory-Erythema, I like to think of Accutane simply as the ACNE compound not a skin compound all in all.

Skin cell turnover rate is another factor that matters but follows the prior principle of it being systemic vs topical. It sounds like an echo chamber but it matters a lot, the retinoids practically all have the same functions with accutane being a systemic version that affects the skin more deeper. But the localised action of topicals beat accutane out for skin APPERANCE.

So Kojo, if this is all true, what do you recommend I do for my skin?

Honestly I won't really overcomplicate it, You just need to attack your skin failos. Assess and diagnose the problem, look for what fixes it.

Spoiler: Methods!

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Skin Texture/Glow/Collagen - Are mainly stimulated by skin cell turnover rate and exfoliation (removing dead skin cells from the skin) in which Topical Retinoids do for you and directly on your skin, alongside chemical exfoliants.

Pairing this with something like glycolic acid can help chemically exfoliate your face, I'd only do this once a week though to avoid over-exfoliation. But imo topical retinoids and a full accutane course will mostly do the job for glowing skin and a good skin texture. (I'm seeing results in 3 days on tazarotene 0.05%)

HOW WE WILL MAINTAIN OUR RESULTS.

Spoiler: Skin Maintenance.

Tazarotene/Tretinoin - Every single Night
Cleanser/Moisturiser - Every morning and Night (Water)
Chemical Exfoliants - Once a week (preferably glycolic acid after skin gets used to retinoid)
Sunscreen - For photoaging, Use whenever going out, especially on a sunny day

Just be hygienic in general, Drink a lot of water and change bed sheets weekly. Wash your hair too.

Keep. It. Simple.

Ngl this originally was supposed to a small discussion on why I think accutane is overrated for skin and how some people misuse it but I guess it turned into a guide-esc post..

You guys can still give some feedback and disagreements though and we can CORDIALLY talk about it under this post.

Love you guys!!

Spoiler: (Some tags)

@nwed @ICL @hate @Final Fantasy @appealisLAW @ecstazy @134applesauce456 @LEFORT17 @eyezen @iqletandrew73

Accutane also causes various problems for your health , including hairloss and other looksmin factors also
Id say just fix diet

 

[ICL]

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

What if I use tyrosinase inhibitors to bleach my skin

Accutane SERIOUSLY is overrated.

"Now why are you saying this Kojo, aren't you THE Accutane enthusiast??"

YES, I am, but it's so misused and coped about because of retards filling this forum and social media with tiktok info from a jester named CLAVICULAR.

Spoiler: My Reasoning.

This idea that you should just "microdose accutane" for skin maintenance is so retarded and is a pseudoscience Clav has pushed out arbitrarily. Accutane does not penetrate the epidermal or Stratum Corneum layers of the skin, which is literally what we all see and feel on our face. This alone is already why topical retinoids are better.

Studies also have shown that Topical retinoids like fucking tretinoin already beat out low dose accutane in photoaging, wrinkles and pigmented skin. Which is what matters for maintaining how good your skin looks mainly. (With some other factors I will address)

Spoiler: Studies!

Low-dose oral isotretinoin versus topical retinoic acid for photoaging: a randomized, comparative study - PubMed

Despite being safe and effective, low-dose ISO was not superior to 0.05% RA for advanced photoaging treatment.

pubmed.ncbi.nlm.nih.gov

Spoiler: Additional Reasoning (A bit Pseudoscientific but Reasonable)

Topical retinoids being applied directly onto the skin give it the advantage of changing the SURFACE of the skin. Accutanes main mechanism of action is the atrophy of Sebaceous glands (Located in the dermal layer), but being a retinoid it also does the other things the other retinoids do at a systemic level.

This is why it's also less effective for the skin because it's a spread out effect that comes from deep within the skins layers contrary to being localised onto the skin surface.

This is also why accutane can't get rid of Post-Inflammatory-Hyperpigmentation or Post-Inflammatory-Erythema, I like to think of Accutane simply as the ACNE compound not a skin compound all in all.

Skin cell turnover rate is another factor that matters but follows the prior principle of it being systemic vs topical. It sounds like an echo chamber but it matters a lot, the retinoids practically all have the same functions with accutane being a systemic version that affects the skin more deeper. But the localised action of topicals beat accutane out for skin APPERANCE.

So Kojo, if this is all true, what do you recommend I do for my skin?

Honestly I won't really overcomplicate it, You just need to attack your skin failos. Assess and diagnose the problem, look for what fixes it.

Spoiler: Methods!

PIH/PIE - Hydroquinone for 3 months, cycle off into Azelaic Acid to maintain your skin from the pigmentation. (for pie use azelaic acid too) Use a retinoid to actually permanently shed that outer layer of your skin that's pigmented.

Azelaic Acid and Hydroquinone are tyrosinase inhibitors so they aren't permanent they just inhibit the melanin on your skin whilst your retinoid will actually shed the skin permanently. It should be permanently fixed within 3-6 months depending on severity.

Acne - Full accutane course, meet a cumulative dose of 150mg * your bodyweight in kg. You will typically get rid of pih/pie after doing this course but if you're giga low inhib you can do it whilst on the course like me. it's burning the shit out of my skin but who cares.

Skin Texture/Glow/Collagen - Are mainly stimulated by skin cell turnover rate and exfoliation (removing dead skin cells from the skin) in which Topical Retinoids do for you and directly on your skin, alongside chemical exfoliants.

Pairing this with something like glycolic acid can help chemically exfoliate your face, I'd only do this once a week though to avoid over-exfoliation. But imo topical retinoids and a full accutane course will mostly do the job for glowing skin and a good skin texture. (I'm seeing results in 3 days on tazarotene 0.05%)

HOW WE WILL MAINTAIN OUR RESULTS.

Spoiler: Skin Maintenance.

Tazarotene/Tretinoin - Every single Night
Cleanser/Moisturiser - Every morning and Night (Water)
Chemical Exfoliants - Once a week (preferably glycolic acid after skin gets used to retinoid)
Sunscreen - For photoaging, Use whenever going out, especially on a sunny day

Just be hygienic in general, Drink a lot of water and change bed sheets weekly. Wash your hair too.

Keep. It. Simple.

Ngl this originally was supposed to a small discussion on why I think accutane is overrated for skin and how some people misuse it but I guess it turned into a guide-esc post..

You guys can still give some feedback and disagreements though and we can CORDIALLY talk about it under this post.

Love you guys!!

Spoiler: (Some tags)

@nwed @ICL @hate @Final Fantasy @appealisLAW @ecstazy @134applesauce456 @LEFORT17 @eyezen @iqletandrew73

Good thread good routine, I was able to read everything. Beware though, don't tag everyone at once, you can only tag 5 people in 1 post before that tag stops notifying the others. Just tag 5 people, then tag 5 the next reply.

 

[ICL]

it alters liver enzymes, makes u sensitive to sun, chap, can cause joint pain, = adjust dose to what works for you and use support and take for 1-2 years or 6-8 on higher dosages you can microdose if you want

All of these side effects are mitigatable. Don't just list the side effects knowing all of them are manegable

 

[tomacōck]

@norwoodingmanlet is a retard, learn to read

 

[appealisLAW]

tretioin is for maintaining the results after isotret course, nothing helped me more than 20mg isotret for clearing the most annoying pimples that kept popping up even while i was applying tretinoin eod. That said i used to have that tretinoin + AA glow when i was on it and skin did look fuller and healthier than on isotret, but not clearer. I would say finish yout isotret course as fast as you can tolerate (only microdose if you must) then tretinoin + azelaic acid for life.

 

[Kojo]

Perfect, I read that it could be permanent due to Accutane shrinking permanently hair follicles

Yeah not sure where that info comes from lol

 

[Kojo]

do i need to exfoliate if i already use tret? can tret alone improve my texture

Yes, tret alone will improve your skin texture by accelerating skin cell turnover rate.

Edit: Exfoliation is just sort of like an extra addition you could add every now and then.

 

[Kojo]

So I should stop taking low dose Accutane and just use tretinoin

For maintaining your skin? absolutely. Accutane is superior for acne though

 

[Kojo]

Accutane also causes various problems for your health , including hairloss and other looksmin factors also
Id say just fix diet

This is cope, everyone hears the "Fix your diet!!" copes and it doesn't work. I did whole foods keto for 6 months straight not a molecule changed and I felt like shit.