Acrutane (tret)

[Deleted member 11370]

So i bought acrutane it says 0.25 tret so i assumes its tret and bought it

now am 17 my collagen levels are not that great ill make sure not to use in under eye and upper eye but the question is will tret make my skin too thin??
Can i use it now or wait till 21

tagging high iqcels @Mongrelcel @RecessedPrettyboy @sandcelmuttcel @EverythingMattersCel

 

[Deleted member 11748]

 

[Htobrother]

So i bought acrutane it says 0.25 tret so i assumes its tret and bought it

now am 17 my collagen levels are not that great ill make sure not to use in under eye and upper eye but the question is will tret make my skin too thin??
Can i use it now or wait till 21

tagging high iqcels @Mongrelcel @RecessedPrettyboy @sandcelmuttcel @EverythingMattersCel

Accutane pills or Tretinoin which you apply on skin?

 

[Deleted member 11370]

Accutane pills or Tretinoin which you apply on skin?

No it literally says Acrutane (0.25 w/w)

 

[Htobrother]

No it literally says Acrutane (0.25 w/w)

It’s called accutane show pic

 

[Deleted member 11370]

It’s called accutane show pic

Mb “acretin”

 

[Htobrother]

Mb “acretin”

Acretin 0,025 is Tretinoin I guess
Why not buy from curry Pharma

 

[Deleted member 11370]

It’s called accutane show pic

 

[Deleted member 11370]

Acretin 0,025 is Tretinoin I guess
Why not buy from curry Pharma View attachment 1131549

Can i use it at 17 or will it thin my skin too much also am in saudi arabia this what we have am not curry

 

[Htobrother]

Can i use it at 17 or will it thin my skin too much also am in saudi arabia this what we have am not curry

Mashalla
Do you have acne ?

 

[Deleted member 11370]

Mashalla
Do you have acne ?

A bit but the skin is not smooth and glowing so i figured tret will help

 

[Htobrother]

A bit but the skin is not smooth and glowing so i figured tret will help

Satori

 

[wagbox]

This is not accutane
Accutane is isotretinoin and this is tretinoin
Very different drugs

 

[ProAcktiv]

no it won't thin your skin. Now go apply it

 

[sandcelmuttcel]

no it won't thin your skin. Now go apply it

it will shrink ur fat pads

Retin-A Causes Loss of Subcutaneous Fat

TLDR: Transretinoic acid impairs the PPAR-gamma transcription factors that control lipogenesis. The bulk of those who experience this effect are relatively young and thus have not dealt with the UV-induced fat loss common in older people, so that is likely why the fat loss is more pronounced and...

looksmax.org

 

[Mongrelcel]

I heard that while retina makes your skin thinner, it makes it thinner by compressing it.

 

[ProAcktiv]

it will shrink ur fat pads

Retin-A Causes Loss of Subcutaneous Fat

TLDR: Transretinoic acid impairs the PPAR-gamma transcription factors that control lipogenesis. The bulk of those who experience this effect are relatively young and thus have not dealt with the UV-induced fat loss common in older people, so that is likely why the fat loss is more pronounced and...

looksmax.org

No, it wont

The studies are in vitro, from what I've seen. They're checking very high concentrations of retinoic acid mixed with strong solvents on cell cultures. This is not what happens when we apply retin A. We apply a low concentration cream on our skin with many more barriers.

The best test is always to see what happens in practice. 99% of users don't experience any sort of "fat pad loss" (if the user is being objective)

Here's 2 studies that say retinoic acid promotes adipogenesis (at lower concentrations). Guess I'll apply retin a to my upper eyelids now so I can get hunter eyes .

Supplementation of All-Trans-Retinoic Acid Below Cytotoxic Levels Promotes Adipogenesis in 3T3-L1 Cells - PubMed

Vitamin A, referred to as retinol, is an essential nutrient that affects the cell growth and differentiation including adipogenesis. Although previous studies using supraphysiological doses (over 1 μM) of all-trans-retinoic acid (atRA) demonstrated antiadipogenic activity, effects of atRA at...

pubmed.ncbi.nlm.nih.gov

"Although previous studies using supraphysiological doses (over 1 μM) of all-trans-retinoic acid (atRA) demonstrated antiadipogenic activity, effects of atRA at various levels on differentiation of 3T3-L1 preadipocytes have not been extensively investigated. Our study showed that the amount of cellular triacylglycerol (TAG) and intensities of Oil-Red-O staining were decreased by supplementing atRA (1 and 10 μM) but increased by low concentrations of atRA (0.01 to 100 nM)"

Research Note: All-trans retinoic acids induce adipogenic differentiation of chicken embryonic fibroblasts and preadipocytes - PubMed

Adipocytes store excess energy in the form of lipids, whereas fat accretion contributes to feed efficiency, meat quality, and female reproduction in poultry. As a metabolite of vitamin A, all-trans retinoic acid (atRA) has been shown to have influence over metabolic functions such as lipid and...

pubmed.ncbi.nlm.nih.gov

Tret is literally one of the oldest drugs bro. If you're scared of tret, it's over.

 

[Deleted member 11370]

Alright just put it on i dont feel redness just like very very small tighter skin ig

its not that annoying like people say am i doing something wrong

 

[Deleted member 11370]

Alright just put it on i dont feel redness just like very very small tighter skin ig

its not that annoying like people say am i doing something wrong

Help

 

[ProAcktiv]

Alright just put it on i dont feel redness just like very very small tighter skin ig

its not that annoying like people say am i doing something wrong

Apply a moisturizer 20 minutes after.... I use vaseline, which works great (salludon does the same thing). But if it's too greasy/thick for you, u can use a regular moisturizer, but it may not do as good a job

 

[Deleted member 11370]

Apply a moisturizer 20 minutes after.... I use vaseline, which works great (salludon does the same thing). But if it's too greasy/thick for you, u can use a regular moisturizer, but it may not do as good a job

Appreciate the great tipbrocel

so tret at morning and night

vaseline after

wash your face twice a say

1k mg vitc sounds good?

 

[sandcelmuttcel]

No, it wont

The studies are in vitro, from what I've seen. They're checking very high concentrations of retinoic acid mixed with strong solvents on cell cultures. This is not what happens when we apply retin A. We apply a low concentration cream on our skin with many more barriers.

The best test is always to see what happens in practice. 99% of users don't experience any sort of "fat pad loss" (if the user is being objective)

Here's 2 studies that say retinoic acid promotes adipogenesis (at lower concentrations). Guess I'll apply retin a to my upper eyelids now so I can get hunter eyes .

Supplementation of All-Trans-Retinoic Acid Below Cytotoxic Levels Promotes Adipogenesis in 3T3-L1 Cells - PubMed

Vitamin A, referred to as retinol, is an essential nutrient that affects the cell growth and differentiation including adipogenesis. Although previous studies using supraphysiological doses (over 1 μM) of all-trans-retinoic acid (atRA) demonstrated antiadipogenic activity, effects of atRA at...

pubmed.ncbi.nlm.nih.gov

"Although previous studies using supraphysiological doses (over 1 μM) of all-trans-retinoic acid (atRA) demonstrated antiadipogenic activity, effects of atRA at various levels on differentiation of 3T3-L1 preadipocytes have not been extensively investigated. Our study showed that the amount of cellular triacylglycerol (TAG) and intensities of Oil-Red-O staining were decreased by supplementing atRA (1 and 10 μM) but increased by low concentrations of atRA (0.01 to 100 nM)"

Research Note: All-trans retinoic acids induce adipogenic differentiation of chicken embryonic fibroblasts and preadipocytes - PubMed

Adipocytes store excess energy in the form of lipids, whereas fat accretion contributes to feed efficiency, meat quality, and female reproduction in poultry. As a metabolite of vitamin A, all-trans retinoic acid (atRA) has been shown to have influence over metabolic functions such as lipid and...

pubmed.ncbi.nlm.nih.gov

Tret is literally one of the oldest drugs bro. If you're scared of tret, it's over.

you know what, there's isn't a clear conclusion yet and all the studies you and the other guy cited are from oral supplementation by the way.

 

[ProAcktiv]

Appreciate the great tipbrocel

so tret at morning and night

vaseline after

wash your face twice a say

1k mg vitc sounds good?

only use tret at night bro. And I've never taken vitamin c orally for skin, so idk tbh. The dosage is fine, I just don't know how effective it is.

Night
1. Cleanse
2. Tret
3. Moisturize with vaseline

Morning
1. Cleanse
2. Apply any active if you're using one. e.g. - vitamin c serum
2. Moisturize (with a regular moisturizer)
4. Sunscreen

 

[Deleted member 11370]

only use tret at night bro. And I've never taken vitamin c orally for skin, so idk tbh. The dosage is fine, I just don't know how effective it is.

Night
1. Cleanse
2. Tret
3. Moisturize with vaseline

Morning
1. Cleanse
2. Apply any active if you're using one. e.g. - vitamin c serum
2. Moisturize (with a regular moisturizer)
4. Sunscreen

Why not just use vaseline as a United moisturizer instead of wasting money and buying 2 different moisturizers

 

[ratiorichard]

might get alopecia i wouldnt risk it man.

 

[Deleted member 11370]

might get alopecia i wouldnt risk it man.

Native got alopecia from accutane not 0.25 tret jfl

 

[ratiorichard]

Native got alopecia from accutane not 0.25 tret jfl

isnt oral and topical absorbed the same.

 

[Deleted member 11370]

isnt oral and topical absorbed the same.

The dosages are not the same its like saying 10000% vit a caused alopecia 0.25 wont cause it even if they are absorbed the same the dosage is too low

 

[ProAcktiv]

isnt oral and topical absorbed the same.

they're not tho

 

[ProAcktiv]

Why not just use vaseline as a United moisturizer instead of wasting money and buying 2 different moisturizers

i guess. but i'm not trynna have a shiny vaseline face when im out. Plus using vaseline too often might work against you. Cuz its thick and greasy and may make your face more oily than it needs to be. Only reason I advised using vaseline is to counteract the drying effect of tret. Otherwise, I would use a regular moisturizer. It doesn't have to be an expensive one.

 

[Deleted member 11370]

i guess. but i'm not trynna have a shiny vaseline face when im out. Plus using vaseline too often might work against you. Cuz its thick and greasy and may make your face more oily than it needs to be. Only reason I advised using vaseline is to counteract the drying effect of tret. Otherwise, I would use a regular moisturizer. It doesn't have to be an expensive one.

 

[ProAcktiv]

View attachment 1132602View attachment 1132602View attachment 1132602

surprised that her acne went away using only vaseline. she's a rare case. But anyway doesn't it say she's using it at night?

 

[Deleted member 11370]

surprised that her acne went away using only vaseline. she's a rare case. But anyway doesn't it say she's using it at night?

These are small results i found on google when searching vaseline on face overnight

 

[Deleted member 11370]

Alright first day documentation no redness and the way of vaseline or tret made my face brighter which kinda sucks since i have sleep related eye bags not bone and it made them more apperant

2- i sweat way more way way more face like face feels hot but from inside not pain its just there like your sweating