aromatose inhibators+ hgh

[Kevla]

what is the best aromatase inhibitors with hgh

 

[Zagro]

Also I want to add more onto this.

Exemestane is irreversible, it binds permanently to the Aromatase enzymes. So if he ever wanted to go back to normal estrogen production, it would be impossible. This is dangerous misinformation that could harm the quality of his sperm, since estradiol does help prevent sperm death.

https://academic.oup.com/jcem/article-abstract/85/5/2057/2660648

Nigga doesn't know that your body produces the enzymes back

 

[LTLightskin]

I already stated that the nuance was not implied, not that your implications were hard to infer; your implications did not exist.
Regardless, you can continue trying to argue with me all you like, but you're an idiot that I won't consider debating because you will shift the goal posts every time I prove you wrong.
Your initial comments were wrong, and I said that... later you can add all the nuance you want, I'll just continue to disregard it.

>Yeah I'm wrong so instead of admitting it, I'm going to claim my opponent is "shifting the goal posts" even though the same premises were kept.

Also still no counter source to my study that aromasin could potentially have a brief estrogen rebound due to the increased endogenous testosterone from aromasin being aromatized. And shame on you for being a sophist, knowing that 99% of the people here aren't autistic enough to know basic pharmacology to refute your BS. Taking advantage of the ignorance so many people here have.

 

[Zagro]

>Yeah I'm wrong so instead of admitting it, I'm going to claim my opponent is "shifting the goal posts" even though the same premises were kept.

Also still no counter source to my study that aromasin could potentially have a brief estrogen rebound due to the increased endogenous testosterone from aromasin being aromatized. And shame on you for being a sophist, knowing that 99% of the people here aren't autistic enough to know basic pharmacology to refute your BS. Taking advantage of the ignorance so many people here have.

The increase in testosterone is temporary is just your lh exceeding the normal work rate, and even if that wasn't the case a short estrogen rebound by your increased endogenous test will be negligible and wont cause any premature ossification to the epiphyses

 

[LTLightskin]

Nigga doesn't know that your body produces the enzymes back

Nigga doesn't know enzyme synthesis has feedback loops and can be downregulated after long durations of needing to compensate for the lack of said enzyme.

 

[LTLightskin]

The increase in testosterone is temporary is just your lh exceeding the normal work rate, and even if that wasn't the case a short estrogen rebound by your increased endogenous test will be negligible and wont cause any premature ossification to the epiphyses

I know, I fully agree with you and earlier I said the rebound only lasts for about a day. It's pretty insignificant since it's only about 10% E2 rebound.

But this fucking retard said aromasin has NO rebound which is bullshit.

 

[Zagro]

Nigga doesn't know enzyme synthesis has feedback loops and can be downregulated after long durations of needing to compensate for the lack of said enzyme.

Yeah ngl i do not know that

 

[LTLightskin]

Yeah ngl i do not know that

It's kinda like how gnrh agonists work.

At first glance, lurpon for example should be increasing GNRH and therefore increasing endogenous hormones and the gonadtropins. But ultimately it overexhuasts the pituitary due to the overly large amounts of GNRH so instead it just shuts down the receptors and downregulates. Stopping all endogenous hormone production.

The same would theoretically happen with the aromatase enzymes, but I didn't find any articles on the long term usage of aromasin in men. But it seems likely this is the case.

But this is protein synthesis, so it's far more complex. I might go ask my med student friend to help me find some studies to come to a more robust explanation and conclusion.

 

[Bitchwhipper2]

That's misinformation.

Exemestane only has a mean inhibition rate of 97.9%.

In vivo inhibition of aromatization by exemestane, a novel irreversible aromatase inhibitor, in postmenopausal breast cancer patients - PubMed

The effect of exemestane (6-methylenandrosta-1,4-diene-3,17-dione) 25 mg p.o. once daily on in vivo aromatization was studied in 10 postmenopausal women with advanced breast cancer. Aromatization was determined before treatment and after 6-8 weeks on therapy by administering a bolus injection of...

pubmed.ncbi.nlm.nih.gov

Like it even matters after 98%

 

[aids]

It's kinda like how gnrh agonists work.

At first glance, lurpon for example should be increasing GNRH and therefore increasing endogenous hormones and the gonadtropins. But ultimately it overexhuasts the pituitary due to the overly large amounts of GNRH so instead it just shuts down the receptors and downregulates. Stopping all endogenous hormone production.

The same would theoretically happen with the aromatase enzymes, but I didn't find any articles on the long term usage of aromasin in men. But it seems likely this is the case.

But this is protein synthesis, so it's far more complex. I might go ask my med student friend to help me find some studies to come to a more robust explanation and conclusion.

Wow, I'm caging.

You provide incorrect blanket statements, try to add nuance to justify as to why you are right in hindsight (disregarding the fact the issue I took was with your blanket statements, not what you might've meant but that is your own fault due to the inability to imply/explicitly state context), then you admit yourself that you are just theorising and there is nothing that actually supports your claims.

This is the type of people I have to argue with? JFL

 

[LTLightskin]

Wow, I'm caging.

You provide incorrect blanket statements, try to add nuance to justify as to why you are right in hindsight (disregarding the fact the issue I took was with your blanket statements, not what you might've meant but that is your own fault due to the inability to imply/explicitly state context), then you admit yourself that you are just theorising and there is nothing that actually supports your claims.

This is the type of people I have to argue with? JFL

Are you genuinely malding over not getting the full reasoning the first time I wrote my paragraph? Maybe you're more autistic than me but how discussions usually work is that there is back and forth. You typically won't get the entire information the first time, which is why you ask questions.

Now I already explained myself...

Then after I explained myself, I repeatedly asked you multiple times to send sources as to why I am or why I might be wrong. You entirely failed at this job. You also lied and said aromasin doesn't have rebound, when even your friend agreed it does.

@Zagro also admitted he didn't know enough about protein synthesis pathways to comment, I'm assuming you're the same. The difference is that you don't want to admit it.

This is genuinely impressive, I've found way more high degree autistics here than on my small Discord servers.

 

[Zagro]

Are you genuinely malding over not getting the full reasoning the first time I wrote my paragraph? Maybe you're more autistic than me but how discussions usually work is that there is back and forth. You typically won't get the entire information the first time, which is why you ask questions.

Now I already explained myself...

Then after I explained myself, I repeatedly asked you multiple times to send sources as to why I am or why I might be wrong. You entirely failed at this job. You also lied and said aromasin doesn't have rebound, when even your friend agreed it does.

@Zagro also admitted he didn't know enough about protein synthesis pathways to comment, I'm assuming you're the same. The difference is that you don't want to admit it.

This is genuinely impressive, I've found way more high degree autistics here than on my small Discord servers.

I barely even talk to him nor do i have enough knowledge regarding this topic or overall knowledge as much as he does. Don’t bring me up to make a point bro

its all indirect, temporary and caused by your endogenous testosterone, as you’ve said yourself aswell its barely anything, so it shouldn’t even be worth pointing out

 

[aids]

Are you genuinely malding over not getting the full reasoning the first time I wrote my paragraph? Maybe you're more autistic than me but how discussions usually work is that there is back and forth. You typically won't get the entire information the first time, which is why you ask questions.

I'm not mad. I'm pointing fun at the fact you made a blanket statement that was blatantly wrong, and then added nuance to try and clarify why you were right in hindsight, after I told you said blanket statement was wrong. I already iterated this but you elect to ignore me saying this because you are of lesser intelligence.

Now I already explained myself...

Then after I explained myself, I repeatedly asked you multiple times to send sources as to why I am or why I might be wrong. You entirely failed at this job. You also lied and said aromasin doesn't have rebound, when even your friend agreed it does.

The burden of proof is on you, you made the claim that sustained steroidal AI use would lead to less aromatase, or lower E2, or whatever the fuck. It is upon you to prove that, not me. All of your 'proof' was theory that you admitted was entirely speculation, you even said you would instead ask a friend because you don't know shit.
I don't know or care for any of the users in this thread, don't associate them with me, they are not necessarily my "friend" just because they interact with me; I don't care what they might say, they are also wrong.
Are there people I like on this forum? Sure, what a stupid fucking assumption to make just because I've interacted with said users.

@Zagro also admitted he didn't know enough about protein synthesis pathways to comment, I'm assuming you're the same. The difference is that you don't want to admit it.

Good for you, don't care. You made a false claim, I told you your claim was false, and you added nuance and are extrapolating from the mechanisms of completely different pharmaceuticals to try and disprove me when in reality, you do not even have evidence, let alone proof, to back up your claims.

This is genuinely impressive, I've found way more high degree autistics here than on my small Discord servers.

Let's take a look at your posts to see if you're projecting...

How to fix narrow mandible 15M?

15M struggilinh with narrow mandible any tips on How to improve

looksmax.org

Retard feigning intellectualism as indicated by his take on AAS for mandibular growth, etc.

Lynch everyone who recommends eroids?

I am tired of seeing a bunch of retarded grey apes recommend that horrible fucking website. It's full of scammers, shills and overpriced roids. Which you better fucking pray they are what they say they are because 8/10 it's underdosed. Yes, this is grey on grey hate. Yes, I am autistic and rage...

looksmax.org

Brutal, fucked up life? Sucks to be you!