Cope methods and compounds. (High effort)

johndoe_

johndoe_

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This is a thread about the various cope methods and the lengths people go through to not get any results.


Today I‘ll be going in depth about the numerous amount of cope methods that go around to this day.

Segments:
  • Pharmaceuticals
  • Orthodontics
  • Social Media born Copes
Each segment will have their own copes and what they are used for. As an example, HGH for height growth in the pharmaceuticals segement.

Starting off with pharmaceuticals, there is a very large range of compounds wich I won‘t be going over with today, since it‘s too much for a single segment. I‘ll be going over the main copes that are most known.

HGH for height growth

HGH for height growth is one of the biggest copes in this forum. The main issue with HGH is that the main issue is that growth plates have finite proliferative capacity, meaning the main source of growth stimulus caused by HGH cannot be driven infinitely. Growth plate
chondrocytes divide and enlargen (hypertrophy), the surrounding matrix then calcifies and is replaced by bone.
What does this mean for you?
You have a finite amount of said proliferative capacity. When it is exhausted, your growth plates stop being able to make enough new chondrocytes, so linear growth slows down and eventually stops.

That being said, there are a few nuances in the HGH cope. Age of use, amount, duration and genetics. If your body dosen’t produce enough chondrocytes you will not grow, and that‘s just genetic. Things like Aromatase Inhibitors are used for lengthening the lifespan of growth plates and how long they stay open. This isn‘t very smart though as estrogen is important for brain developement and also muscle at that.
If all your using is HGH and you don‘t have an abundance of estrogen, you will quite literally make yourself retarded long term.

HGH can make you taller depending on a lot of circumstances, it‘s just not worth it for most people / there is a genetic limit to how much growth can be achieved by using it.


The functions were kept quite simple. I‘ll also link all the studies used to make this thread below.

GHKCU for acne
Most people in this forum are aware that GHKCU isn‘t a compound used for things like hormonal acne. Although it‘s still a widespread belief by many uneducated people.

GHKCU is a copper peptide wich is mainly known for its collagen signaling and increasing properties.

Why does it not work for acne?

Acne is not mainly caused by having not enough collagen.
The main acne drivers are
  • Excess sebum production
  • Inflammation around the (hair) follicle
  • Follicular hyperkeratinization (dead skin cells cloggint pores)
  • Cutibacterium acnes activity (Bacterial acne)
GHK Cu does not target any of the said main drivers through its function of increasing collagen.

It does not significantly reduce sebum or sebum production, it does not help with follicular shedding, it‘s not a strong anti cutibacterium acnes treatment (and no, „balancing bacteria“ does not mean anything)
Its anti inflammatory effect is too non specific.



There is alot more to cover than just these 2. they are the ones I see being tossed around the most.
If you want another thread on a specific compound let me know.

I‘ll also only be going over 2 parts of orthodontics as it‘s also a huge field with a large variety of methodology and treatment plans.

Palatal expanders
Palatal expanders are some of the most popular orthognatic devices right now. I‘ll be going over why they can be a looksmin and also the use of headgear with palatal expanders.

There are many different types of palatal expanders, for this thread I‘ll reference implant supported expanders (screwed into the maxilla, i.e marpe, sarpe etc.)

Before I get into the explanation, I want to mention that palatal expanders can be benificial in alot of use cases, especially depending on age and goals.

Firstly, we need to establish the most common use cases of a MARPE device.

The main uses of implant supported expanders are
  • Posterior crossbite
  • Narrow maxillary palate
  • Sometimes nasal airway restrictions related to a narrow nasal floor
The mentioned points also include the consequences of said point. For example, a narrow smile due to a posterior crossbite.

Why a palatal expander isn‘t a good idea if you don‘t fit the main uses

Getting a palatal expander when you don‘t have any related bite issues will almost always result in a misaligned bite. Your orthodontist will not be able to give you the results you want without making your bite worse, because expansion over the mandible can cause dental tipping or something like a posterior scissor bite.

Some of the main issues even if you have the dental/palatal need for an expanding device:
  • Nose/Alar base widening
  • Enhancing pre-existing asymmemtries
  • Bad bizygo to bigonial ratio
The mandible does not get structurally wider like the maxilla does. Meaning if your bigonial wasnt the widest before, it‘d be worse after.

The best case scenario for someone with a normal bite looking into a palatal expander is mildly expanding your palate while maintaining a stable bite for little or no difference in appearance. Alongside that, if your maxilla isn‘t projected forwards, expanding your palate can make your face look even flatter.

Subtopic: Headgear with a palatal expander

Another big trend in the looksmax community right now is getting headgear with a palatal expander as an adult for forward growth.

This topic is quite simple.

The first issue is that a MARPE or SARPE device targets the midpalatal suture that targets width, not the circummaxillary suture wich targets length.

The second one is that your circummaxillary suture fuses relatively early on. Studies show a range of 16-18 as the average.

The conlusion is that your circummaxillary suture is still fused and will not move significantly. Yes it can adjust to your midpaltal suture and zygomaticomaxillary suture changes, that dosen‘t mean the suture is open and gives reliable growth.

The misconseption stems from the combination being used in children, where it is in fact helpful. A majority of the anecdotal evidence shown by people are soft tissue and inner dental changes, not actual maxillary forward growth.

Again, there are many nuances in both of these topics, but for most it‘s quite useless and not worth the ROI. The time and money for a potential looksmin or no changes isn‘t worth it.

Many new types of cope have been created with the popularisation of looksmaxxing. These „methods“ may have existed before although they werent nearly as mainstream as they are now.

This is quite the retarded segment, but unfortunately I do have to get into these topics as you see multiple people asking if they work daily on this forum.

Thumb pulling
Thumb pulling is the idea of pulling your maxilla to increase width and or forward growth. People who believe this works claim that the effects are similar to that of a palatal expander, because the function is „similar“.

1. The force required for maxillary movement are nowhere near orthopedic expansion

RME devices can output up to 30 lbs of force on the maxilla 24/7. Your thumbs won‘t. Alongside that you can‘t be doing it 24/7. Including sleep, work/school thats a major amount of time with no pressure on your maxilla.

To summarize:
  • You cannot apply enough force consistently
  • You cannot maintain the force long enough
  • The force is inconsistent
  • You don‘t have symmetrical force output on your maxilla
2. Temporary soft tissue changes

The roof of your mouth is covered by soft tissue. This tissue can get „compressed“ or inflamed and will look and maybe even feel different. You might feel like you have more space for your tounge because of bone changes, when in reality only the palatal soft tissue changed.


That‘s basically all I‘ll be mentioning for thumbpulling, as it‘s quite braindead anyways.

Note: This also heavily contradicts orthodontic treatment. I‘ll be linking midpalatal and circummaxillary suture fusion studies wich tie into the orthognatic segment.


What am I trying to say with this thread?
The goal is just to point out the huge amount of methods that don‘t work. I don‘t think anyone should be investing their time or money on things that wouldn‘t benifit them, especially with a possibly limited amount of time.

Do whatever you can to ascend. That‘s what matters.

If anything I said is untrue or not accurate, please let me know and cite the study so I can change or remove it.

All sources are pretty much in order. From the hgh part down to the thumbpulling part.

 
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Reactions: youriblamegenetics
NZK after calling HGH cope
only the case for retards who run it on its own
 
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Reactions: nsabi67
Read the entire segment jfl
im not talking about ai eithers
sure they can help for a few extra cm when used with gh but theres much better shit and ais have very limited effects on local aromatization
 
Mirin, read it all brah
 
  • +1
Reactions: youriblamegenetics and johndoe_
This is a thread about the various cope methods and the lengths people go through to not get any results.


Today I‘ll be going in depth about the numerous amount of cope methods that go around to this day.

Segments:
  • Pharmaceuticals
  • Orthodontics
  • Social Media born Copes
Each segment will have their own copes and what they are used for. As an example, HGH for height growth in the pharmaceuticals segement.

Starting off with pharmaceuticals, there is a very large range of compounds wich I won‘t be going over with today, since it‘s too much for a single segment. I‘ll be going over the main copes that are most known.

HGH for height growth

HGH for height growth is one of the biggest copes in this forum. The main issue with HGH is that the main issue is that growth plates have finite proliferative capacity, meaning the main source of growth stimulus caused by HGH cannot be driven infinitely. Growth plate
chondrocytes divide and enlargen (hypertrophy), the surrounding matrix then calcifies and is replaced by bone.
What does this mean for you?
You have a finite amount of said proliferative capacity. When it is exhausted, your growth plates stop being able to make enough new chondrocytes, so linear growth slows down and eventually stops.

That being said, there are a few nuances in the HGH cope. Age of use, amount, duration and genetics. If your body dosen’t produce enough chondrocytes you will not grow, and that‘s just genetic. Things like Aromatase Inhibitors are used for lengthening the lifespan of growth plates and how long they stay open. This isn‘t very smart though as estrogen is important for brain developement and also muscle at that.
If all your using is HGH and you don‘t have an abundance of estrogen, you will quite literally make yourself retarded long term.

HGH can make you taller depending on a lot of circumstances, it‘s just not worth it for most people / there is a genetic limit to how much growth can be achieved by using it.


The functions were kept quite simple. I‘ll also link all the studies used to make this thread below.

GHKCU for acne
Most people in this forum are aware that GHKCU isn‘t a compound used for things like hormonal acne. Although it‘s still a widespread belief by many uneducated people.

GHKCU is a copper peptide wich is mainly known for its collagen signaling and increasing properties.

Why does it not work for acne?

Acne is not mainly caused by having not enough collagen.
The main acne drivers are
  • Excess sebum production
  • Inflammation around the (hair) follicle
  • Follicular hyperkeratinization (dead skin cells cloggint pores)
  • Cutibacterium acnes activity (Bacterial acne)
GHK Cu does not target any of the said main drivers through its function of increasing collagen.

It does not significantly reduce sebum or sebum production, it does not help with follicular shedding, it‘s not a strong anti cutibacterium acnes treatment (and no, „balancing bacteria“ does not mean anything)
Its anti inflammatory effect is too non specific.



There is alot more to cover than just these 2. they are the ones I see being tossed around the most.
If you want another thread on a specific compound let me know.

I‘ll also only be going over 2 parts of orthodontics as it‘s also a huge field with a large variety of methodology and treatment plans.

Palatal expanders
Palatal expanders are some of the most popular orthognatic devices right now. I‘ll be going over why they can be a looksmin and also the use of headgear with palatal expanders.

There are many different types of palatal expanders, for this thread I‘ll reference implant supported expanders (screwed into the maxilla, i.e marpe, sarpe etc.)

Before I get into the explanation, I want to mention that palatal expanders can be benificial in alot of use cases, especially depending on age and goals.

Firstly, we need to establish the most common use cases of a MARPE device.

The main uses of implant supported expanders are
  • Posterior crossbite
  • Narrow maxillary palate
  • Sometimes nasal airway restrictions related to a narrow nasal floor
The mentioned points also include the consequences of said point. For example, a narrow smile due to a posterior crossbite.

Why a palatal expander isn‘t a good idea if you don‘t fit the main uses

Getting a palatal expander when you don‘t have any related bite issues will almost always result in a misaligned bite. Your orthodontist will not be able to give you the results you want without making your bite worse, because expansion over the mandible can cause dental tipping or something like a posterior scissor bite.

Some of the main issues even if you have the dental/palatal need for an expanding device:
  • Nose/Alar base widening
  • Enhancing pre-existing asymmemtries
  • Bad bizygo to bigonial ratio
The mandible does not get structurally wider like the maxilla does. Meaning if your bigonial wasnt the widest before, it‘d be worse after.

The best case scenario for someone with a normal bite looking into a palatal expander is mildly expanding your palate while maintaining a stable bite for little or no difference in appearance. Alongside that, if your maxilla isn‘t projected forwards, expanding your palate can make your face look even flatter.

Subtopic: Headgear with a palatal expander

Another big trend in the looksmax community right now is getting headgear with a palatal expander as an adult for forward growth.

This topic is quite simple.

The first issue is that a MARPE or SARPE device targets the midpalatal suture that targets width, not the circummaxillary suture wich targets length.

The second one is that your circummaxillary suture fuses relatively early on. Studies show a range of 16-18 as the average.

The conlusion is that your circummaxillary suture is still fused and will not move significantly. Yes it can adjust to your midpaltal suture and zygomaticomaxillary suture changes, that dosen‘t mean the suture is open and gives reliable growth.

The misconseption stems from the combination being used in children, where it is in fact helpful. A majority of the anecdotal evidence shown by people are soft tissue and inner dental changes, not actual maxillary forward growth.

Again, there are many nuances in both of these topics, but for most it‘s quite useless and not worth the ROI. The time and money for a potential looksmin or no changes isn‘t worth it.

Many new types of cope have been created with the popularisation of looksmaxxing. These „methods“ may have existed before although they werent nearly as mainstream as they are now.

This is quite the retarded segment, but unfortunately I do have to get into these topics as you see multiple people asking if they work daily on this forum.

Thumb pulling
Thumb pulling is the idea of pulling your maxilla to increase width and or forward growth. People who believe this works claim that the effects are similar to that of a palatal expander, because the function is „similar“.

1. The force required for maxillary movement are nowhere near orthopedic expansion

RME devices can output up to 30 lbs of force on the maxilla 24/7. Your thumbs won‘t. Alongside that you can‘t be doing it 24/7. Including sleep, work/school thats a major amount of time with no pressure on your maxilla.

To summarize:
  • You cannot apply enough force consistently
  • You cannot maintain the force long enough
  • The force is inconsistent
  • You don‘t have symmetrical force output on your maxilla
2. Temporary soft tissue changes

The roof of your mouth is covered by soft tissue. This tissue can get „compressed“ or inflamed and will look and maybe even feel different. You might feel like you have more space for your tounge because of bone changes, when in reality only the palatal soft tissue changed.


That‘s basically all I‘ll be mentioning for thumbpulling, as it‘s quite braindead anyways.

Note: This also heavily contradicts orthodontic treatment. I‘ll be linking midpalatal and circummaxillary suture fusion studies wich tie into the orthognatic segment.


What am I trying to say with this thread?
The goal is just to point out the huge amount of methods that don‘t work. I don‘t think anyone should be investing their time or money on things that wouldn‘t benifit them, especially with a possibly limited amount of time.

Do whatever you can to ascend. That‘s what matters.

If anything I said is untrue or not accurate, please let me know and cite the study so I can change or remove it.

All sources are pretty much in order. From the hgh part down to the thumbpulling part.

Can agree but this is mostly tiktokcel's cope. In reality, most people on this forum should be able to fish out copes when obvious
 
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hgh for height is cope?
are you forgetting doctors perscribe it to children with with idiopathic short stature
suicide of your credibility as a user
 
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Can agree but this is mostly tiktokcel's cope. In reality, most people on this forum should be able to fish out copes when obvious
Yeah, that‘s true. I didn‘t go too in depth about most things because people with high enough IQ to understand either way. This is mostly a thread for people entirely new to the forum.
 
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Yeah, that‘s true. I didn‘t go too in depth about most things because people with high enough IQ to understand either way. This is mostly a thread for people entirely new to the forum.
Good principle
 
hgh for height is cope?
are you forgetting doctors perscribe it to children with with short stature
suicide of your credibility as a user
Lol Idiopathic short stature just means they don‘t know the cause. Could be an IGF-1 sensitivity issue, a GH deficiency issue, they just don‘t know. Key word in your comment is „children“ though. Also the average height expectancy for children with ISS is rougly 1-2 inches taller then their predicted height without HGH.
 
Lol Idiopathic short stature just means they don‘t know the cause. Could be an IGF-1 sensitivity issue, a GH deficiency issue, they just don‘t know. Key word in your comment is „children“ though. Also the average height expectancy for children with ISS is rougly 1-2 inches taller then their predicted height without HGH.
The 1-2 inch average includes late starters and poor compliance so optimised early protocols show significantly better outcomes also ur wrong about IGF-1 sensitivity since that supports a more targeted protocol not writing off GH entirely
 
The 1-2 inch average includes late starters and poor compliance so optimised early protocols show significantly better outcomes also ur wrong about IGF-1 sensitivity since that supports a more targeted protocol not writing off GH entirely
That‘s fair but it undermines the children starting HGH at early ages and good complianfe. Overall it avrages out.


This is a study on children with ISS and finding causes. Basically, it‘s irrelevant. I think we can both agree most 13-15 year olds aren‘t capable of buying hgh and or won‘t inject anything. The biggest amount of people looking into HGH for growth are 16-21 year olds. That dosen‘t come close to the recommended age of starting HGH therapy for ISS at 4-13.
 
im not talking about ai eithers
sure they can help for a few extra cm when used with gh but theres much better shit and ais have very limited effects on local aromatization
Like what? I don‘t know of any such compounds. Are you talking about FGFR3 inhibitors? CNP analogs?
 
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Like what? I don‘t know of any such compounds. Are you talking about FGFR3 inhibitors? CNP analogs?
That sort of things theres also cheap shit just to boost velocity like ct and much other stuff dyor
 
That sort of things theres also cheap shit just to boost velocity like ct and much other stuff dyor
I did do my own research. CNP analogs and FGFR3 are the only reliable things that could stimulate chondrocytes realistically. But also realistically your not getting your hands on them. They are hard to source and cost alot (if they are real). FGFR3 inhibitors are less promising in regular people without achondroplasia. I‘ll look into your claim though.

Keeping it realistic, most teenagers 15+ on this forum looking to grow taller with HGH and other compounds won‘t be able to. My point still stands.

If I do come across a compound wich can help get you through your genetic cap I‘ll follow up.
 
That sort of things theres also cheap shit just to boost velocity like ct and much other stuff dyor
Also, boosting growth velocity is irrelevant. Yes there could be compounds that increase height velocity (like hgh) but they don‘t bypass your actual genetic height cap. This is heavily dependant on growth velocity + open growth plate time left. Growth plate senescense and remaining chondrocyte capacity are still a huge factor.

That being said there is no research in regular non deficient children using FGFR3 inhibitors or CNP analogs. We have no real clinical data and even the compounds I mentioned are still developing to some degree.

If you don‘t have anything else, it‘s still just cope to me.
 
what about Isotrerinoin?
 
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Also, boosting growth velocity is irrelevant. Yes there could be compounds that increase height velocity (like hgh) but they don‘t bypass your actual genetic height cap. This is heavily dependant on growth velocity + open growth plate time left. Growth plate senescense and remaining chondrocyte capacity are still a huge factor.
You are so retarded lmao
Increased epSSCs proliferation increases "genetic limit" but you have to make sure actualy chondrocyte hyperthropy happens

That being said there is no research in regular non deficient children using FGFR3 inhibitors or CNP analogs.
There is research in mice and there even are FDA approved FGFR inhibs, just afaik no selective one
Theres still clinical trials (phase 2) on humans for Dabo which is selective
compounds I mentioned are still developing to some degree.
So what?
Just say youre either a retard who cant handle correctly taking those or youre a pussy and scared of the possible sides

Muh no human research does not make them any less valuable
If you don‘t have anything else, it‘s still just cope to me.
Solutions are cope sure:lul::lul:
Ky19382, Indirubin, navep, increlex, leucine, romos all cope

Gtfo with you "jewpt tell me 3 reasond why xyz is cope" slop:lul:
 
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Dudes after their mom said no to getting prescribed hgh or approved for marpe. :ROFLMAO:
 
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