Debunking Deca

20/04/2008 said:
It improves sensitivity to prolactin
Run deca only cycle (test it incase) if your prolactin goes up significantly im the biggest fraud of org and you have the right to insult my ass
I don’t post studies cause its retarded if you want some pm me cause the high iq are mf that steal my work and diss me in the comments and the low iq ones suck their cock and continue harrasing me
I don’t use deca currently but would after 19-20 cause it fuck with your seretonin transmitter in the brain
But deca = best hrt protocol
Uhm for libido not optimal but your dick would still work even better if you were hypogonadol before
Click to expand...
nah nigger im honest fucking with roids is stupid, cant you just research kisspeptin 10
 
übermog said:
why did back then nobody lose his hair on winnie
Click to expand...
Cause 4 weeks exposition
And they had high estrogen cause they didn’t use ai
 
20/04/2008 said:
Cause 4 weeks exposition
And they had high estrogen cause they didn’t use ai
Click to expand...
if i do short cycles sides will be less, funny timing thats what i was researching about just now
 
Nandrolone literally converts to prolactin. Thats why some people get black milk shit out of there gyno when on deca or tren
 
IBlameSub3 said:
Nandrolone literally converts to prolactin. Thats why some people get black milk shit out of there gyno when on deca or tren
Click to expand...
no it doesn’t
It sensitizes the receptors but doesn’t increase it on bloodwork which would give you gyno if your run deca with progesteronic compound because your gonna be super sensitive to prolactin
Tren do increase prolactin
 
meathead said:
ratio is useless

all studies are with fat free mass and not very useful
Click to expand...
true but still in studies deca mogs tf out of test without estrogen :lul::lul::lul:
 
20/04/2008 said:
true but still in studies deca mogs tf out of test without estrogen :lul::lul::lul:
Click to expand...
yea but u can just u 3x the dosages get the same amount of muscle with less side effects
 
meathead said:
yea but u can just u 3x the dosages get the same amount of muscle with less side effects
Click to expand...
no yes i dont know like wtf did yo just i dont know how to respond to this
did you read the study where they used a g of primo on women and they got 0 sides
well run 150 mg of test with 1g of primo
 
20/04/2008 said:
no yes i dont know like wtf did yo just i dont know how to respond to this
did you read the study where they used a g of primo on women and they got 0 sides
well run 150 mg of test with 1g of primo
Click to expand...
i meant with test

yea primo mogs
 
20/04/2008 said:
why is a deca base cycle better than testosterone base? Well, for one it brings an alternative to a hormone replacement base in a steroid cycle. As it has been used for androgen deficiency studies in males. And has been used as such solo without testosterone in HIV aids males for this very purpose. Why is deca used over test? Well because simply it provided better benefits, muscle growth, fewer side effects and reports of better quality of life.

(Remember every drug that came after test was meant to have less side effects and more anabolic effects exept some exeptions fluoxymesterone was made before testosterone and equipose and trenbolone were made for animal not humans, and superdrol and trestolone dhb are new drugs so they don’t count)

Majority of guys fear anabolics due to the side effects such as hair loss, gynecomastia, water retention, acne, acne scars and even the emotional sides. So they search for safer alternatives a lot of the times which usually doesn’t end up bringing the results either.

Deca, simply put from real-world results such as from bodybuilders from the 60s to late 80s, Mike menzter, Robby Robinson, Danny padilla and countless more many great names, As well from studies shows us how little the sides from it truly are in regards to the aforementioned sides above. Hair loss, Gynecomastia, Acne you just did not see it back then.

Hair loss? Science wise near impossible unless very high doses. Real-world results wise? I have seen guys regrow hair on reedit after switching from test to deca .



Gynecomastia? Science-wise gynecomastia is due to an off androgen to estrogen ratio. And deca science wise simply put is always in a very favorable ratio. Real-world results wise? I’ve never seen it happened even with guys that were prone to gyno off less than 100mg of testosterone yet could use again multiple grams of deca with ZERO estrogenic symptoms. The only times I have seen this happened was with guys using shady sources where I got them to test their product and lab work to reveal they had testosterone not deca in their product. Which surprisingly happens i guess so disclaimer if you can afford it always test your shit especially drugs that are expensive.



Acne? Real-world results and science wise we just do not see it happen. Nothing more to be said here.

Water retention? A study showed there was no fluid increase on this drug and bodybuilders in the 60s to late 80s used this drug as a contest prep drug as well, and so have my followers and clients. It is a very lean drug and many would compare it to a weaker tren. Dr. Robert Kerr who treated many bodybuilders in 70s 80s also reports this to be a dry drug with no water retention and is a great contest prep drug.

Deca shuts your testosterone down? Of course it does, all steroids do. What matters is we replace this drug with an androgen that can support our male functions. Dianabol, Deca (nandrolone), Equipoise all fit that bill. The big reason being here is they are all androgens that also convert to estrogen. Which is needed for androgens to even work on the androgen receptor period. This is why DHT drugs will not work as a base. Studies show without estrogen DHT drugs solo can make animals very timid and loss of sex drive, gain body fat and insulin resistance and even digestion goes down the drain due to estrogen being needed for pancreatic function on enzymes for digestion.

Prolactin? Well, zero studies have ever shown deca to ever raise prolactin, not a single one ever. And the only study showing us this shows it lowered prolactin compared to testosterone raising it. So deca lowers prolactin.

Libido loss? Never been heard of by any old pro bodybuilder when this was a staple as a base without testosterone, nor has a single report ever been recorded by the world health organization either unlike testosterone. The issue here is when testosterone use became popular and added to the mix. Deca simply put will make the side effect galore drug testosterone even worse. Helping aromatization of testosterone to estrogen and receptor sensitivity. Making testosterone an even worse drug leading to more sides such as libido loss. Again not a single study on deca used solo has ever reported it causing any sort of libido loss. And it has been used many times solo.

Conclusion. Why use testosterone, why when so many get sides off even 100mg of testosterone. Gynecomastia, bloating, acne, hair loss, for what? It isn’t needed to replace male function, seminal vessel health, prostate health, etc. Deca can do this and better at it for what we are doing here. We are not using anabolics for just a replacement effect. And if you are, then this topic isn’t for you and no need to consider anything but your TRT. When a bodybuilder or someone looking for an anabolic effect we are looking at using something that is above normal ranges for a purpose. And that purpose mainly is anabolism. Go and run 500mg of testosterone and your estrogen goes x5 the normal range. And prolactin all also goes up. Leading to all of our lovely sides that we now need to run Anti Aromatize drugs at high doses, which worsen heart, bone health and cause hair loss by themselves. Yet when we go and run 500mg of an anabolic drug like deca, we now have the effect we want, a high dose of anabolism. Yet our secondary hormone profiles are at a normal dose range similar to that using a TRT dose base of testosterone.

Can one run a test base say 100mg with an anabolic like deca as your main drug, such as 100mg testosterone with 500mg plus of deca? Sure. But I am sure many of you have read online and have experienced for yourself, countless users get side effects off even just 100mg of testosterone. Then this might not be the option for you when deca can replace all of your needs without the side effects.

simply put there is no need for testosterone or testosterone at high doses.

Tags : @Clavicular
@Dyorotic
@MA_ascender
@Jonas2k7
@Sapieeen
@NZb6Air
@ConfusedBolivian
@androgenic
Click to expand...
Wtf ? You must be joking
Deca is the worst of all
Libido loss , gyno , deca dick , water retention , feeling depressed and shit , shutdown forever if you use nandrolone then be prepared to blast and cruise as pct is useless in such cases
No one today in the modern bodybuilding world uses deca and if they do that's cuz they have lost their last braincels on it as researches have proven that nandrolones degrade your iq far far worse than test.
Pls stay away from deca , tren and such shit I'll say that even tren is better than deca it's really shit .
 
5.5psl said:
Wtf ? You must be joking
Deca is the worst of all
Libido loss , gyno , deca dick , water retention , feeling depressed and shit , shutdown forever if you use nandrolone then be prepared to blast and cruise as pct is useless in such cases
No one today in the modern bodybuilding world uses deca and if they do that's cuz they have lost their last braincels on it as researches have proven that nandrolones degrade your iq far far worse than test.
Pls stay away from deca , tren and such shit I'll say that even tren is better than deca it's really shit .
Click to expand...
currently on 700 npp with 300 eq 0 sides
i had gyno before from my natty hormones
i could get gyno from 100 test
yet im on 700 npp 0 gyno
my libido is not as high as when i was on test but i could perform 4x no probs
i feel less fluid on deca than test
the only downside is i dont feel as hyped ups when i wason tes like i lost that drive but other thab that deca mogs
nigg i tried other steroids i can tell deca as hrt mogs
 
20/04/2008 said:
why is a deca base cycle better than testosterone base? Well, for one it brings an alternative to a hormone replacement base in a steroid cycle. As it has been used for androgen deficiency studies in males. And has been used as such solo without testosterone in HIV aids males for this very purpose. Why is deca used over test? Well because simply it provided better benefits, muscle growth, fewer side effects and reports of better quality of life.

(Remember every drug that came after test was meant to have less side effects and more anabolic effects exept some exeptions fluoxymesterone was made before testosterone and equipose and trenbolone were made for animal not humans, and superdrol and trestolone dhb are new drugs so they don’t count)

Majority of guys fear anabolics due to the side effects such as hair loss, gynecomastia, water retention, acne, acne scars and even the emotional sides. So they search for safer alternatives a lot of the times which usually doesn’t end up bringing the results either.

Deca, simply put from real-world results such as from bodybuilders from the 60s to late 80s, Mike menzter, Robby Robinson, Danny padilla and countless more many great names, As well from studies shows us how little the sides from it truly are in regards to the aforementioned sides above. Hair loss, Gynecomastia, Acne you just did not see it back then.

Hair loss? Science wise near impossible unless very high doses. Real-world results wise? I have seen guys regrow hair on reedit after switching from test to deca .



Gynecomastia? Science-wise gynecomastia is due to an off androgen to estrogen ratio. And deca science wise simply put is always in a very favorable ratio. Real-world results wise? I’ve never seen it happened even with guys that were prone to gyno off less than 100mg of testosterone yet could use again multiple grams of deca with ZERO estrogenic symptoms. The only times I have seen this happened was with guys using shady sources where I got them to test their product and lab work to reveal they had testosterone not deca in their product. Which surprisingly happens i guess so disclaimer if you can afford it always test your shit especially drugs that are expensive.



Acne? Real-world results and science wise we just do not see it happen. Nothing more to be said here.

Water retention? A study showed there was no fluid increase on this drug and bodybuilders in the 60s to late 80s used this drug as a contest prep drug as well, and so have my followers and clients. It is a very lean drug and many would compare it to a weaker tren. Dr. Robert Kerr who treated many bodybuilders in 70s 80s also reports this to be a dry drug with no water retention and is a great contest prep drug.

Deca shuts your testosterone down? Of course it does, all steroids do. What matters is we replace this drug with an androgen that can support our male functions. Dianabol, Deca (nandrolone), Equipoise all fit that bill. The big reason being here is they are all androgens that also convert to estrogen. Which is needed for androgens to even work on the androgen receptor period. This is why DHT drugs will not work as a base. Studies show without estrogen DHT drugs solo can make animals very timid and loss of sex drive, gain body fat and insulin resistance and even digestion goes down the drain due to estrogen being needed for pancreatic function on enzymes for digestion.

Prolactin? Well, zero studies have ever shown deca to ever raise prolactin, not a single one ever. And the only study showing us this shows it lowered prolactin compared to testosterone raising it. So deca lowers prolactin.

Libido loss? Never been heard of by any old pro bodybuilder when this was a staple as a base without testosterone, nor has a single report ever been recorded by the world health organization either unlike testosterone. The issue here is when testosterone use became popular and added to the mix. Deca simply put will make the side effect galore drug testosterone even worse. Helping aromatization of testosterone to estrogen and receptor sensitivity. Making testosterone an even worse drug leading to more sides such as libido loss. Again not a single study on deca used solo has ever reported it causing any sort of libido loss. And it has been used many times solo.

Conclusion. Why use testosterone, why when so many get sides off even 100mg of testosterone. Gynecomastia, bloating, acne, hair loss, for what? It isn’t needed to replace male function, seminal vessel health, prostate health, etc. Deca can do this and better at it for what we are doing here. We are not using anabolics for just a replacement effect. And if you are, then this topic isn’t for you and no need to consider anything but your TRT. When a bodybuilder or someone looking for an anabolic effect we are looking at using something that is above normal ranges for a purpose. And that purpose mainly is anabolism. Go and run 500mg of testosterone and your estrogen goes x5 the normal range. And prolactin all also goes up. Leading to all of our lovely sides that we now need to run Anti Aromatize drugs at high doses, which worsen heart, bone health and cause hair loss by themselves. Yet when we go and run 500mg of an anabolic drug like deca, we now have the effect we want, a high dose of anabolism. Yet our secondary hormone profiles are at a normal dose range similar to that using a TRT dose base of testosterone.

Can one run a test base say 100mg with an anabolic like deca as your main drug, such as 100mg testosterone with 500mg plus of deca? Sure. But I am sure many of you have read online and have experienced for yourself, countless users get side effects off even just 100mg of testosterone. Then this might not be the option for you when deca can replace all of your needs without the side effects.

simply put there is no need for testosterone or testosterone at high doses.

Tags : @Clavicular
@Dyorotic
@MA_ascender
@Jonas2k7
@Sapieeen
@NZb6Air
@ConfusedBolivian
@androgenic
Click to expand...
@jordy4382
 
20/04/2008 said:
why is a deca base cycle better than testosterone base? Well, for one it brings an alternative to a hormone replacement base in a steroid cycle. As it has been used for androgen deficiency studies in males. And has been used as such solo without testosterone in HIV aids males for this very purpose. Why is deca used over test? Well because simply it provided better benefits, muscle growth, fewer side effects and reports of better quality of life.

(Remember every drug that came after test was meant to have less side effects and more anabolic effects exept some exeptions fluoxymesterone was made before testosterone and equipose and trenbolone were made for animal not humans, and superdrol and trestolone dhb are new drugs so they don’t count)

Majority of guys fear anabolics due to the side effects such as hair loss, gynecomastia, water retention, acne, acne scars and even the emotional sides. So they search for safer alternatives a lot of the times which usually doesn’t end up bringing the results either.

Deca, simply put from real-world results such as from bodybuilders from the 60s to late 80s, Mike menzter, Robby Robinson, Danny padilla and countless more many great names, As well from studies shows us how little the sides from it truly are in regards to the aforementioned sides above. Hair loss, Gynecomastia, Acne you just did not see it back then.

Hair loss? Science wise near impossible unless very high doses. Real-world results wise? I have seen guys regrow hair on reedit after switching from test to deca .



Gynecomastia? Science-wise gynecomastia is due to an off androgen to estrogen ratio. And deca science wise simply put is always in a very favorable ratio. Real-world results wise? I’ve never seen it happened even with guys that were prone to gyno off less than 100mg of testosterone yet could use again multiple grams of deca with ZERO estrogenic symptoms. The only times I have seen this happened was with guys using shady sources where I got them to test their product and lab work to reveal they had testosterone not deca in their product. Which surprisingly happens i guess so disclaimer if you can afford it always test your shit especially drugs that are expensive.



Acne? Real-world results and science wise we just do not see it happen. Nothing more to be said here.

Water retention? A study showed there was no fluid increase on this drug and bodybuilders in the 60s to late 80s used this drug as a contest prep drug as well, and so have my followers and clients. It is a very lean drug and many would compare it to a weaker tren. Dr. Robert Kerr who treated many bodybuilders in 70s 80s also reports this to be a dry drug with no water retention and is a great contest prep drug.

Deca shuts your testosterone down? Of course it does, all steroids do. What matters is we replace this drug with an androgen that can support our male functions. Dianabol, Deca (nandrolone), Equipoise all fit that bill. The big reason being here is they are all androgens that also convert to estrogen. Which is needed for androgens to even work on the androgen receptor period. This is why DHT drugs will not work as a base. Studies show without estrogen DHT drugs solo can make animals very timid and loss of sex drive, gain body fat and insulin resistance and even digestion goes down the drain due to estrogen being needed for pancreatic function on enzymes for digestion.

Prolactin? Well, zero studies have ever shown deca to ever raise prolactin, not a single one ever. And the only study showing us this shows it lowered prolactin compared to testosterone raising it. So deca lowers prolactin.

Libido loss? Never been heard of by any old pro bodybuilder when this was a staple as a base without testosterone, nor has a single report ever been recorded by the world health organization either unlike testosterone. The issue here is when testosterone use became popular and added to the mix. Deca simply put will make the side effect galore drug testosterone even worse. Helping aromatization of testosterone to estrogen and receptor sensitivity. Making testosterone an even worse drug leading to more sides such as libido loss. Again not a single study on deca used solo has ever reported it causing any sort of libido loss. And it has been used many times solo.

Conclusion. Why use testosterone, why when so many get sides off even 100mg of testosterone. Gynecomastia, bloating, acne, hair loss, for what? It isn’t needed to replace male function, seminal vessel health, prostate health, etc. Deca can do this and better at it for what we are doing here. We are not using anabolics for just a replacement effect. And if you are, then this topic isn’t for you and no need to consider anything but your TRT. When a bodybuilder or someone looking for an anabolic effect we are looking at using something that is above normal ranges for a purpose. And that purpose mainly is anabolism. Go and run 500mg of testosterone and your estrogen goes x5 the normal range. And prolactin all also goes up. Leading to all of our lovely sides that we now need to run Anti Aromatize drugs at high doses, which worsen heart, bone health and cause hair loss by themselves. Yet when we go and run 500mg of an anabolic drug like deca, we now have the effect we want, a high dose of anabolism. Yet our secondary hormone profiles are at a normal dose range similar to that using a TRT dose base of testosterone.

Can one run a test base say 100mg with an anabolic like deca as your main drug, such as 100mg testosterone with 500mg plus of deca? Sure. But I am sure many of you have read online and have experienced for yourself, countless users get side effects off even just 100mg of testosterone. Then this might not be the option for you when deca can replace all of your needs without the side effects.

simply put there is no need for testosterone or testosterone at high doses.

Tags : @Clavicular
@Dyorotic
@MA_ascender
@Jonas2k7
@Sapieeen
@NZb6Air
@ConfusedBolivian
@androgenic
Click to expand...
@1xc6
 
meathead said:
even besides the studies so many people reported a worsening of their mental health, lack of motivation

recommending deca or test is stupid
Click to expand...
Why test?
 
Test is best fuck other roids
 
halloweed said:
Test is best fuck other roids
Click to expand...
Deca is superior in every way imaginable

The only downsides is it doesn’t give you the drive and aggression test gives you

Deca would be used for someone that wanna get the most results while having perfects bloods

While test would for someone to be the Most Nt as possible
 
20/04/2008 said:
Deca is superior in every way imaginable

The only downsides is it doesn’t give you the drive and aggression test gives you

Deca would be used for someone that wanna get the most results while having perfects bloods

While test would for someone to be the Most Nt as possible
Click to expand...

17β-trenbolone, an anabolic–androgenic steroid as well as an environmental hormone, contributes to neurodegeneration (Journal Article) | OSTI.GOV

Both genetic and environmental factors contribute to neurodegenerative disorders. In a large number of neurodegenerative diseases (for example, Alzheimer's disease (AD)), patients do not carry the mutant genes. Other risk factors, for example the environmental factors, should be evaluated...
www.osti.gov www.osti.gov
pubmed.ncbi.nlm.nih.gov

Nandrolone decanoate induces genetic damage in multiple organs of rats - PubMed

To evaluate the impact potential of nandrolone decanoate on DNA damage in multiple organs of Wistar rats by means of single-cell gel (comet) assay and micronucleus test. A total of 15 animals were distributed into three groups of five animals each as follows: control group = animal not exposed...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
www.academia.edu

Chronic nandrolone administration induces dysfunction of the reward pathway in rats

Data in animal models and surveys in humans have revealed psychiatric complications of long-term anabolic androgenic steroid abuse. However, the neurobiochemical mechanisms behind the observed behavioral changes are poorly understood.
www.academia.edu

The Impact of Nandrolone Decanoate on the Central Nervous System - PMC

Nandrolone is included in the class II of anabolic androgenic steroids (AAS) which is composed of 19-nor-testosterone-derivates. In general, AAS is a broad and rapidly increasing group of synthetic androgens used both clinically and illicitly. AAS ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
www.academia.edu

Voluntary exercise does not ameliorate spatial learning and memory deficits induced by chronic administration of nandrolone decanoate in rats

Anabolic androgenic steroids Nandrolone decanoate Morris water maze Learning Memory Voluntary exercise BDNF Rat Chronic exposure to the anabolic androgenic steroids (AAS) nandrolone decanoate (ND) in supra-physiological doses is associated with
www.academia.edu
 
halloweed said:

17β-trenbolone, an anabolic–androgenic steroid as well as an environmental hormone, contributes to neurodegeneration (Journal Article) | OSTI.GOV

Both genetic and environmental factors contribute to neurodegenerative disorders. In a large number of neurodegenerative diseases (for example, Alzheimer's disease (AD)), patients do not carry the mutant genes. Other risk factors, for example the environmental factors, should be evaluated...
www.osti.gov www.osti.gov
pubmed.ncbi.nlm.nih.gov

Nandrolone decanoate induces genetic damage in multiple organs of rats - PubMed

To evaluate the impact potential of nandrolone decanoate on DNA damage in multiple organs of Wistar rats by means of single-cell gel (comet) assay and micronucleus test. A total of 15 animals were distributed into three groups of five animals each as follows: control group = animal not exposed...
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
www.academia.edu

Chronic nandrolone administration induces dysfunction of the reward pathway in rats

Data in animal models and surveys in humans have revealed psychiatric complications of long-term anabolic androgenic steroid abuse. However, the neurobiochemical mechanisms behind the observed behavioral changes are poorly understood.
www.academia.edu

The Impact of Nandrolone Decanoate on the Central Nervous System - PMC

Nandrolone is included in the class II of anabolic androgenic steroids (AAS) which is composed of 19-nor-testosterone-derivates. In general, AAS is a broad and rapidly increasing group of synthetic androgens used both clinically and illicitly. AAS ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
www.academia.edu

Voluntary exercise does not ameliorate spatial learning and memory deficits induced by chronic administration of nandrolone decanoate in rats

Anabolic androgenic steroids Nandrolone decanoate Morris water maze Learning Memory Voluntary exercise BDNF Rat Chronic exposure to the anabolic androgenic steroids (AAS) nandrolone decanoate (ND) in supra-physiological doses is associated with
www.academia.edu
Click to expand...
Nigga i can find a study that shows that test is more neurotoxic then deca

If deca is so neurotoxic is because of Low estrogen cause that shit don’t aromatize you can make deca 11x safer by just using smth like dbol or topical estrogen
 
20/04/2008 said:
  1. Introduction
  1. Using rat tests, 4-week treatment with nandrolone was shown to produce an anxious phenotype in rodents[1].
  2. But several studies have confirmed a depressive phenotype from deca that is dissimilar from testosterone.
  1. Chronic (4-week) nandrolone treatment has been shown to induce a reduction in sweet-taste (sucralose) preference, which is an indicator of anhedonia[2].
  1. Note that SSRIs increase sucralose preference in rats.
  2. Serotonin, noradrenaline, and dopamine levels in the nucleus acumens (which transmits dopamine while the animal eats sucralose) were all reduced.
  1. 6 week nandrolone treatment decreased NPY neuron availability in the hippocampus and decrease NPY blood levels, which are thought to associate well with pituitary NPY levels[3].
  1. NPY expression is lower in the depressed.
  1. 4-week treatment with nandrolone produced a depressive and anhedonic state associated with increased activating of the kynurenine pathway, an alternate metabolism for tryptophan[4].
  1. Tryptophan is mainly catabolized by the kynurenine pathway which yields neuroactive compounds including kynurenine.
  2. An alternate metabolism for tryptophan is towards serotonin, which has consistently been lowered in deca users.
  1. Study Design[5]
  1. 18 rats were divided into control, deca, and test.
  2. Deca and test given injections every 3rd day for 18 days.
  3. Blood levels, behavior, and brain matter were analysed.
  1. Results:
  1. The majority of alterations were region specific to the hypothalamus:
  2. Nandrolone more than testosterone upregulates mRNA transcription of the oxytocin receptor gene.
  3. Oxytocin regulates food intake and sexual behavior.
  4. In this study on rats, nandrolone decanoate rats experienced less body weight gain than control or testosterone undecanoate rats.
  1. It forms a complex with dopaminergic neurons.
  1. The effect of oxytocin injection on behavioral changes in rats is inhibited by the dopamine antagonist haloperidol and partially abolished by the MOR antagonist naloxone[6].
  1. Oxytocin transmission occurs after stressful events.
  2. Oxytocin receptors, neurons, and levels are found to be increased in the depressed.
  1. Nandrolone and testosterone also upregulated the neuropeptide Y 1 and 5 receptor expression in the hypothalamus, and NPY is also thought to regulate food intake.
  1. Nandrolone upregulated the 1R less and 5R more.
  1. The authors predict that this effect is AR dependent, as it occurs more in deca than test groups but occurs in both and deca has a higher affinity for the androgen receptor.
  1. Deca only produces less effect on pubic and scalp AR due to being transformed by 5AR into a weaker androgen.
  2. Previously, oxytocin genes were shown to be regulated by AR expression in the hypothalamus.
  1. Stress hormone levels:
  1. Adrenocorticotropic hormone was reduced more in the deca group than the test group, but both lower than control.
  2. Corticosterone was reduced in the testosterone group but increased from control in the deca group.
  3. This is the rat equivalent of cortisol. Deca increases cortisol from baseline.
  1. Behavior:
  1. Deca group gained less bodyweight.
  2. Deca group moved less, overall.
  3. It was previously shown that testosterone could increase movement, where deca decreased it[7].
  1. Takeaways
  1. Deca consistently produces a depressive phenotype in rats, though it inconsistently produces an anxious phenotype.
  2. Anhedonic people tend to complain, while anxious people tend to switch the subject a lot.
  3. Alterations in the oxytocin, neuropeptide y, and monoamine pathways may explain these changes.


Deca Worsens Blood Sugar Control​

  1. Introduction
  2. It is known that GH worsens insulin sensitivity and produces full-fledged diabetes in acromegalics.
  3. Physiologic testosterone improves lipolysis and insulin sensitivity.
  4. What about supraphysiologic amounts of steroids? Historical studies have exhibited worsened glucose metabolism.
  5. In this study, we examine the effects of supraphysiologic doses on the metabolisms of rats.
  1. Design
  1. Rats in a control, low dose deca, and high dose deca group.
  1. Results
  1. Body composition:
  2. Deca treatment increased muscle mass and water content.
  3. Deca treatment decreased total fat mass but not visceral fat (only IM and SubQ).
  1. Insulin resistance in muscle:
  1. OGTT tests were the same, but reduced skeletal muscle uptake in response to insulin was found with deca.
  2. Specific muscle insulin insensitivity (metformin?).
  1. Serum levels:
  1. Serum glucose levels are lower in the deca group.
  2. However, serum insulin levels are higher, implying a potential role for deca directly at the pancreas.
  1. Glucose production while fasting:
  1. Glucose can be produced by glycolysis of glycerol from fat tissue or from gluconeogenesis.
  2. Deca treatment increases glycerol, potentially due to triglyceride breakdown or impaired gluconeogenesis.
  3. High dose deca impaired gluconeogenesis (from glycerol, lactate, or amino acids).
  1. Insulin resistance at the liver:
  1. Liver glycogen levels are also lower.
  2. Liver glucokinase also decreased.
  1. It is unclear how these changes occur, suggestions made:
  1. Reduced glucocorticoid activity.
  2. Reduced thyroid activity.


[1] Rosic, G., Joksimovic, J., Selakovic, D., Milovanovic, D., & Jakovljevic, V. (2014). Anxiogenic effects of chronic exposure to nandrolone decanoate (ND) at supraphysiological dose in rats: a brief report. Neuroendocrinol Lett, 35(703), 10.
[2] Zotti, M., Tucci, P., Colaianna, M., Morgese, M. G., Mhillaj, E., Schiavone, S., ... & Trabace, L. (2014). Chronic nandrolone administration induces dysfunction of the reward pathway in rats. Steroids, 79, 7-13.
[3] Joksimovic, J., Selakovic, D., Matovic, M., Zaletel, I., Puskas, N., & Rosic, G. (2017). The role of neuropeptide-Y in nandrolone decanoate-induced attenuation of antidepressant effect of exercise. PLoS One, 12(6), e0178922.
[4] Souza, L. C., de Brito, M. L. O., Jesse, C. R., Boeira, S. P., de Gomes, M. G., Goes, A. T. R., ... & Nogueira, C. W. (2020). Involvement of kynurenine pathway in depressive-like behaviour induced by nandrolone decanoate in mice. Steroids, 164, 108727.
[5] Zelleroth, S., Nylander, E., Kjellgren, E., Grönbladh, A., & Hallberg, M. (2022). Nandrolone decanoate and testosterone undecanoate differently affect stress hormones, neurotransmitter systems, and general activity in the male rat. Behavioural Brain Research, 432, 113971.
[6] Drago, F., Pedersen, C. A., Caldwell, J. D., & Prange Jr, A. J. (1986). Oxytocin potently enhances novelty-induced grooming behavior in the rat. Brain research, 368(2), 287-295.
[7] McGinnis, M. Y., Lumia, A. R., Tetel, M. J., Molenda-Figueira, H. A., & Possidente, B. (2007). Effects of anabolic androgenic steroids on the development and expression of running wheel activity and circadian rhythms in male rats. Physiology & behavior, 92(5), 1010-1018.

Here is some more i read all of the deca is shit studies and i still think its good
You know what they share in common all of them have atleast 1 big failo
Aslong your above 21 i would still reccomend deca over testosterone
Click to expand...
@halloweed
 
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Reactions: halloweed
20/04/2008 said:
I know about that study
That why i choose 11 jfl
Click to expand...
Yeahh I was wondering that number is so specific
But there is probably no way to reduce it other than excessive vasodilation which comes with risks
 
halloweed said:
Yeahh I was wondering that number is so specific
But there is probably no way to reduce it other than excessive vasodilation which comes with risks
Click to expand...
Vitamin D3 and igf-1 helps with that

All roids do the same thing bro its just depends of the strength of the compound
 
meathead said:

⚠️ Nandrolone and Trenbolone​

🟠 Manifold Health Risks​

  • Nandrolone is 11 times more damaging to blood vessels than Testosterone, causes longstanding changes in the brain reward system, adversely impacts learning and memory, and induces genetic damage across multiple organ systems.

🟡 Long-term suppression​

  • 19-nor compounds Trenbolone and Nandrolone—excluding Trestolone (MENT), which has a half-life of forty minutes and is twice as fast to recover from as Testosterone itself—are highly suppressive for up to 12–18 months. No one should take Nandrolone or other 19-nor compounds unless they're already on blast and cruise (BnC), because full recovery from PCT will be rendered largely ineffective.
  • Trenbolone metabolizes into 17α-Trenbolone, 17β-Trenbolone and Trendione. Each of these compounds are able to convert into one another, which substantially prolongs the elimination time.
  • Long term perturbation of HPTA axis, endocrine and cholesterol levels after discontinuing AAS

🔴 Neurodegeneration​

🔴 Genetic damage​

🔴 Cardiovascular system​

🔴 Reward system dysfunction​

🔴 Cognitive deficits​

Click to expand...
High iq
 
20/04/2008 said:
Cause its more anabolic
280 Npp = 450 test E
Click to expand...
Is that cope

500 test
400 tren
1.25mg letro eod+1mg of fin 3x weekly
0.25mg cabro 2x per week

This cycle for 14 months
Tren is for 10 weeks only
Chatgbt cope only right
Bone age 16/5'8
 

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halloweed said:
Send
Click to expand...
1) AT, and Aldosterone Receptors Blockade Prevents the Chronic Effect of Nandrolone on the Exercise-Induced Cardioprotection in Perfused rat Heart Subjected to Ischemia and Reperfusion


Silvio Rodrigues Marques-Neto • Emanuelle Baptista Ferraz• Deivid Carvalho Rodrigues • Brian Njaine • Edson Rondinelli - Antônio Carlos Campos de Carvalho • Jose Hamilton Matheus Nascimento

2)
OrgaNext Research: Addition of Vitamin D improves Safety Profile of Nandrolone


48 25. 30722 00.41 88 02


HOUSTON -DRINESS WIRE) - A recent in vitro study by the Dutch company Orgalert Research demoratrates that addition of vitamin D to nandrolone not only synergistically stimulates the proliferation of skeletal muscle stem cells, but also improves the salety prefle of nandrolone.

3)
GH improves spatial memory and reverses certain anabolic androgenic steroid-induced effects in intact rats


AJIN#d Grönbladh, Jenny Johanson, Anabala Nbuti, Fred Nyberg and


Mathias Hallberg


Му РФ Вак St, 8-297.24

4)
latrogenic dependence of anabolic-androgenic steroid in an Indian non-athletic woman


Adarsh Tripathi, ' Bheemsain Tekkalaki,' Shashwat Saxena, ' Himanshu Dandu?
 
mattmogstomumbai said:
Is that cope

500 test
400 tren
1.25mg letro eod+1mg of fin 3x weekly
0.25mg cabro 2x per week

This cycle for 14 months
Tren is for 10 weeks only
Chatgbt cope only right
Bone age 16/5'8
Click to expand...
400 tren jfl
 
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Reactions: mattmogstomumbai
i thought u were talking about that after school club
 
Really considering deca if and when I graduate from sarms
 
meathead said:
ratio is useless

all studies are with fat free mass and not very useful
Click to expand...
Well deca is dryer than test
And yet caused higher Fat free mass increase
While also the participants suffered from Crushed E2 which isn’t good if you wanna put on soze and yet they gained more ffm than the test group
 
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